Toxoplasmosis is a parasitic and zoonotic disease caused by Toxoplasma gondii.
The disease has worldwide distribution and all people maybe under the risk of getting infected
by the parasite. The overall aim of this research was to detect the prevalence rate of antiToxoplasma
gondii IgM and IgG among diabetic patients in Makkah, Saudi Arabia. Blood
samples were collected from diabetic patients. Toxo IgM and IgG combo rapid test cassette
were used to screen the samples, and the results were confirmed by using Enzyme-Linked
Immunosorbent Assay (ELISA) to detect anti-IgM and anti- IgG antibodies on the plasma of 90
diabetic patients who attended the mobile clinic or AL Noor hospital in Makkah area. The
subject was asked to complete a structured questionnaire. The questionnaire data and
serological results were analyzed by using SPSS 20. Chi-square was used to compare different
variables. Out of 90 samples, 39 (43.3%) were positive to anti-Toxoplasma gondii IgG wherein
33 (36.6%) of them were male and 6 (6.7%) were female. The age ranged between 13–85
years with the mean of 49.9 years. The study found that there were statistical differences
between the age groups with higher prevalence in the 50-65 years age group. Detection of
IgM against T. gondii gave negative results. The results of the study indicate that latent T.
gondii in diabetic patient are relatively high especially among the 50-65 age group. There
were significant associated between direct contact with a cat and infection by T. gondii
(p