Displaying publications 1 - 20 of 115 in total

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  1. Li Y, Wang Y, Liu Z, Zainal Abidin IM, Chen Z
    Sensors (Basel), 2019 Sep 23;19(19).
    PMID: 31547499 DOI: 10.3390/s19194102
    The cladded conductor is broadly utilized in engineering fields, such as aerospace, energy, and petrochemical; however, it is vulnerable to thickness loss occurring in the clad layer and nonconductive protection coating due to abrasive and corrosive environments. Such a flaw severely undermines the integrity and safety of the mechanical structures. Therefore, evaluating the thickness loss hidden inside cladded conductors via reliable nondestructive evaluation techniques is imperative. This paper intensively investigates the pulse-modulation eddy current technique (PMEC) for the assessment of thickness loss in a cladded conductor. An analytical model of the ferrite-cored probe is established for analyzing PMEC signals and characteristics of lift-off intersection (LOI) in testing signals. Experiments are conducted for evaluation of the thickness loss in cladded conductors. An inverse scheme based on LOI for estimation of the thickness-loss depth is proposed and further verified. Through simulations and experiments, it is found that the influences of the thickness loss in the clad layer and protective coating on the PMEC signals can be decoupled in virtue of the LOI characteristics. Based on LOI, the hidden thickness loss can be efficiently evaluated without much of a reduction in accuracy by using the PMEC probe for dedicated inspection of the cladded conductor.
  2. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Jul 12;123(2):022001.
    PMID: 31386524 DOI: 10.1103/PhysRevLett.123.022001
    The transverse momentum spectra of D^{0} mesons from b hadron decays are measured at midrapidity (|y|<1) in pp and Pb-Pb collisions at a nucleon-nucleon center of mass energy of 5.02 TeV with the CMS detector at the LHC. The D^{0} mesons from b hadron decays are distinguished from prompt D^{0} mesons by their decay topologies. In Pb-Pb collisions, the B→D^{0} yield is found to be suppressed in the measured p_{T} range from 2 to 100  GeV/c as compared to pp collisions. The suppression is weaker than that of prompt D^{0} mesons and charged hadrons for p_{T} around 10  GeV/c. While theoretical calculations incorporating partonic energy loss in the quark-gluon plasma can successfully describe the measured B→D^{0} suppression at higher p_{T}, the data show an indication of larger suppression than the model predictions in the range of 2
  3. Lin C, Chen Z, Zhang L, Wei Z, Cheng KK, Liu Y, et al.
    Parasit Vectors, 2019 Jun 13;12(1):300.
    PMID: 31196218 DOI: 10.1186/s13071-019-3554-0
    BACKGROUND: Hepatic alveolar echinococcosis (HAE) is caused by the growth of Echinococcus multilocularis larvae in the liver. It is a chronic and potentially lethal parasitic disease. Early stage diagnosis for this disease is currently not available due to its long asymptomatic incubation period. In this study, a proton nuclear magnetic resonance (1H NMR)-based metabolomics approach was applied in conjunction with multivariate statistical analysis to investigate the altered metabolic profiles in blood serum and urine samples obtained from HAE patients. The aim of the study was to identify the metabolic signatures associated with HAE.

    RESULTS: A total of 21 distinct metabolic differences between HAE patients and healthy individuals were identified, and they are associated with perturbations in amino acid metabolism, energy metabolism, glyoxylate and dicarboxylate metabolism. Furthermore, the present results showed that the Fischer ratio, which is the molar ratio of branched-chain amino acids to aromatic amino acids, was significantly lower (P 

  4. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Apr 19;122(15):152001.
    PMID: 31050516 DOI: 10.1103/PhysRevLett.122.152001
    The modification of jet shapes in Pb-Pb collisions, relative to those in pp collisions, is studied for jets associated with an isolated photon. The data were collected with the CMS detector at the LHC at a nucleon-nucleon center-of-mass energy of 5.02 TeV. Jet shapes are constructed from charged particles with track transverse momenta (p_{T}) above 1  GeV/c in annuli around the axes of jets with p_{T}^{jet}>30  GeV/c associated with an isolated photon with p_{T}^{γ}>60  GeV/c. The jet shape distributions are consistent between peripheral Pb-Pb and pp collisions, but are modified for more central Pb-Pb collisions. In these central Pb-Pb events, a larger fraction of the jet momentum is observed at larger distances from the jet axis compared to pp, reflecting the interaction between the partonic medium created in heavy ion collisions and the traversing partons.
  5. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Apr 19;122(15):151802.
    PMID: 31050519 DOI: 10.1103/PhysRevLett.122.151802
    For the first time, a search for the rare decay of the W boson to three charged pions has been performed. Proton-proton collision data recorded by the CMS experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 77.3  fb^{-1}, have been analyzed. No significant excess is observed above the background expectation. An upper limit of 1.01×10^{-6} is set at 95% confidence level on the branching fraction of the W boson to three charged pions. This provides a strong motivation for theoretical calculations of this branching fraction.
  6. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Apr 05;122(13):132003.
    PMID: 31012605 DOI: 10.1103/PhysRevLett.122.132003
    The observation of single top quark production in association with a Z boson and a quark (tZq) is reported. Events from proton-proton collisions at a center-of-mass energy of 13 TeV containing three charged leptons (either electrons or muons) and at least two jets are analyzed. The data were collected with the CMS detector in 2016 and 2017 and correspond to an integrated luminosity of 77.4fb^{-1}. The increased integrated luminosity, a multivariate lepton identification, and a redesigned analysis strategy improve significantly the sensitivity of the analysis compared to previous searches for tZq production. The tZq signal is observed with a significance well over 5 standard deviations. The measured tZq production cross section is σ(pp→tZq→tℓ^{+}ℓ^{-}q)=111±13(stat)_{-9}^{+11}(syst)  fb, for dilepton invariant masses above 30 GeV, in agreement with the standard model expectation.
  7. Guo G, Zhang W, Dang M, Yan M, Chen Z
    J. Biochem. Mol. Toxicol., 2019 Apr;33(4):e22268.
    PMID: 30431692 DOI: 10.1002/jbt.22268
    Overexpression of human epidermal growth factor receptor 2 (HER2) is observed in breast cancer. The major snag faced by the human population is the development of chemoresistance to HER2 inhibitors by advanced stage breast cancer cells. Moreover, recent researchers focussed on fisetin as an antiproliferative and chemotherapeutic agent. Therefore, this study was intended to analyze the effects of fisetin on HER2/neu-overexpressing breast cancer cell lines. Our results depicted that fisetin induced apoptosis of these cells by various mechanisms, such as inactivation of the receptor, induction of proteasomal degradation, decreasing its half-life, decreasing enolase phosphorylation, and alteration of phosphatidylinositol 3-kinase/Akt signaling.
  8. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Mar 29;122(12):121803.
    PMID: 30978057 DOI: 10.1103/PhysRevLett.122.121803
    This Letter describes a search for Higgs boson pair production using the combined results from four final states: bbγγ, bbττ, bbbb, and bbVV, where V represents a W or Z boson. The search is performed using data collected in 2016 by the CMS experiment from LHC proton-proton collisions at sqrt[s]=13  TeV, corresponding to an integrated luminosity of 35.9  fb^{-1}. Limits are set on the Higgs boson pair production cross section. A 95% confidence level observed (expected) upper limit on the nonresonant production cross section is set at 22.2 (12.8) times the standard model value. A search for narrow resonances decaying to Higgs boson pairs is also performed in the mass range 250-3000 GeV. No evidence for a signal is observed, and upper limits are set on the resonance production cross section.
  9. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Mar 01;122(8):081804.
    PMID: 30932612 DOI: 10.1103/PhysRevLett.122.081804
    A search for heavy, narrow resonances decaying to a Higgs boson and a photon (Hγ) has been performed in proton-proton collision data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9  fb^{-1} collected with the CMS detector at the LHC in 2016. Events containing a photon and a Lorentz-boosted hadronically decaying Higgs boson reconstructed as a single, large-radius jet are considered, and the γ+jet invariant mass spectrum is analyzed for the presence of narrow resonances. To increase the sensitivity of the search, events are categorized depending on whether or not the large-radius jet can be identified as a result of the merging of two jets originating from b quarks. Results in both categories are found to agree with the predictions of the standard model. Upper limits on the production rate of Hγ resonances are set as a function of their mass in the range of 720-3250 GeV, representing the most stringent constraints to date.
  10. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Jan 18;122(2):021801.
    PMID: 30720313 DOI: 10.1103/PhysRevLett.122.021801
    A search for the Higgs boson decaying to two oppositely charged muons is presented using data recorded by the CMS experiment at the CERN LHC in 2016 at a center-of-mass energy sqrt[s]=13  TeV, corresponding to an integrated luminosity of 35.9  fb^{-1}. Data are found to be compatible with the predicted background. For a Higgs boson with a mass of 125.09 GeV, the 95% confidence level observed (background-only expected) upper limit on the production cross section times the branching fraction to a pair of muons is found to be 3.0 (2.5) times the standard model expectation. In combination with data recorded at center-of-mass energies sqrt[s]=7 and 8 TeV, the background-only expected upper limit improves to 2.2 times the standard model value with a standard model expected significance of 1.0 standard deviation. The corresponding observed upper limit is 2.9 with an observed significance of 0.9 standard deviation. This corresponds to an observed upper limit on the standard model Higgs boson branching fraction to muons of 6.4×10^{-4} and to an observed signal strength of 1.0±1.0(stat)±0.1(syst).
  11. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Phys. Rev. Lett., 2019 Jan 11;122(1):011803.
    PMID: 31012697 DOI: 10.1103/PhysRevLett.122.011803
    A search is performed for dark matter particles produced in association with a top quark pair in proton-proton collisions at sqrt[s]=13  TeV. The data correspond to an integrated luminosity of 35.9  fb^{-1} recorded by the CMS detector at the LHC. No significant excess over the standard model expectation is observed. The results are interpreted using simplified models of dark matter production via spin-0 mediators that couple to dark matter particles and to standard model quarks, providing constraints on the coupling strength between the mediator and the quarks. These are the most stringent collider limits to date for scalar mediators, and the most stringent for pseudoscalar mediators at low masses.
  12. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(2):90.
    PMID: 30814908 DOI: 10.1140/epjc/s10052-019-6556-3
    A search is presented for the single production of vector-like quarks in proton-proton collisions at


    s

    =
    13

    TeV

    . The data, corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    , were recorded with the CMS experiment at the LHC. The analysis focuses on the vector-like quark decay into a top quark and a
    W
    boson, with one muon or electron in the final state. The mass of the vector-like quark candidate is reconstructed from hadronic jets, the lepton, and the missing transverse momentum. Methods for the identification of
    b
    quarks and of highly Lorentz boosted hadronically decaying top quarks and
    W
    bosons are exploited in this search. No significant deviation from the standard model background expectation is observed. Exclusion limits at 95% confidence level are set on the product of the production cross section and branching fraction as a function of the vector-like quark mass, which range from 0.3 to 0.03


    pb

    for vector-like quark masses of 700 to 2000


    GeV

    . Mass exclusion limits up to 1660


    GeV

    are obtained, depending on the vector-like quark type, coupling, and decay width. These represent the most stringent exclusion limits for the single production of vector-like quarks in this channel.
  13. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(4):313.
    PMID: 31031568 DOI: 10.1140/epjc/s10052-019-6788-2
    A top quark mass measurement is performed using

    35.9



    fb

    -
    1




    of LHC proton-proton collision data collected with the CMS detector at


    s

    =
    13

    TeV

    . The measurement uses the

    t

    t
    ¯


    all-jets final state. A kinematic fit is performed to reconstruct the decay of the

    t

    t
    ¯


     system and suppress the multijet background. Using the ideogram method, the top quark mass (

    m
    t

    ) is determined, simultaneously constraining an additional jet energy scale factor (
    JSF
    ). The resulting value of


    m
    t

    =
    172.34
    ±
    0.20

    (stat+JSF)
    ±
    0.70

    (syst)

    GeV

    is in good agreement with previous measurements. In addition, a combined measurement that uses the

    t

    t
    ¯


    lepton+jets and all-jets final states is presented, using the same mass extraction method, and provides an

    m
    t

    measurement of

    172.26
    ±
    0.07

    (stat+JSF)
    ±
    0.61

    (syst)

    GeV

    . This is the first combined

    m
    t

    extraction from the lepton+jets and all-jets channels through a single likelihood function.
  14. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(2):123.
    PMID: 30863200 DOI: 10.1140/epjc/s10052-019-6620-z
    Measurements of normalized differential cross sections as functions of the multiplicity and kinematic variables of charged-particle tracks from the underlying event in top quark and antiquark pair production are presented. The measurements are performed in proton-proton collisions at a center-of-mass energy of 13



    Te



    , and are based on data collected by the CMS experiment at the LHC in 2016 corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    . Events containing one electron, one muon, and two jets from the hadronization and fragmentation of
    b
    quarks are used. These measurements characterize, for the first time, properties of the underlying event in top quark pair production and show no deviation from the universality hypothesis at energy scales typically above twice the top quark mass.
  15. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(3):269.
    PMID: 30971865 DOI: 10.1140/epjc/s10052-019-6752-1
    Measurements are presented of associated production of a
    W
    boson and a charm quark (

    W
    +
    c

    ) in proton-proton collisions at a center-of-mass energy of 13



    Te



    . The data correspond to an integrated luminosity of 35.7



    fb

    -
    1



    collected by the CMS experiment at the CERN LHC. The
    W
    bosons are identified by their decay into a muon and a neutrino. The charm quarks are tagged via the full reconstruction of



    D








    (
    2010
    )

    ±


    mesons that decay via




    D








    (
    2010
    )

    ±





    D

    0

    +

    π
    ±




    K



    +

    π
    ±

    +

    π
    ±


    . A cross section is measured in the fiducial region defined by the muon transverse momentum


    p

    T

    μ

    >
    26


    Ge



    , muon pseudorapidity


    |


    η
    μ


    |
    <
    2.4


    , and charm quark transverse momentum


    p

    T

    c

    >
    5


    Ge



    . The inclusive cross section for this kinematic range is

    σ

    (
    W
    +
    c
    )

    =
    1026
    ±
    31

    (stat)





    +
    76







    -
    72






    (syst) pb

    . The cross section is also measured differentially as a function of the pseudorapidity of the muon from the
    W
    boson decay. These measurements are compared with theoretical predictions and are used to probe the strange quark content of the proton.
  16. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(3):280.
    PMID: 31007587 DOI: 10.1140/epjc/s10052-019-6730-7
    A search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks is performed in proton-proton collisions at a center-of-mass energy of 13



    Te



    collected with the CMS detector at the LHC. The analyzed data sample corresponds to an integrated luminosity of 35.9



    fb

    -
    1



    . The signal is characterized by a large missing transverse momentum recoiling against a bottom quark-antiquark system that has a large Lorentz boost. The number of events observed in the data is consistent with the standard model background prediction. Results are interpreted in terms of limits both on parameters of the type-2 two-Higgs doublet model extended by an additional light pseudoscalar boson
    a
    (2HDM+
    a
    ) and on parameters of a baryonic


    Z

    '

    simplified model. The 2HDM+
    a
    model is tested experimentally for the first time. For the baryonic


    Z

    '

    model, the presented results constitute the most stringent constraints to date.
  17. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(4):305.
    PMID: 31007588 DOI: 10.1140/epjc/s10052-019-6800-x
    A search is presented for resonant production of second-generation sleptons (


    μ
    ~

    L

    ,


    ν
    ~

    μ

    ) via the R-parity-violating coupling

    λ
    211
    '

    to quarks, in events with two same-sign muons and at least two jets in the final state. The smuon (muon sneutrino) is expected to decay into a muon and a neutralino (chargino), which will then decay into a second muon and at least two jets. The analysis is based on the 2016 data set of proton-proton collisions at


    s

    =
    13

    TeV

    recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    . No significant deviation is observed with respect to standard model expectations. Upper limits on cross sections, ranging from 0.24 to 730


    fb

    , are derived in the context of two simplified models representing the dominant signal contributions leading to a same-sign muon pair. The cross section limits are translated into coupling limits for a modified constrained minimal supersymmetric model with

    λ
    211
    '

    as the only nonzero R-parity violating coupling. The results significantly extend restrictions of the parameter space compared with previous searches for similar models.
  18. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(2):94.
    PMID: 30872972 DOI: 10.1140/epjc/s10052-019-6562-5
    A search is presented for decays of
    Z
    and Higgs bosons to a

    J
    /
    ψ

    meson and a photon, with the subsequent decay of the

    J
    /
    ψ

    to


    μ
    +


    μ
    -


    . The analysis uses data from proton-proton collisions with an integrated luminosity of 35.9



    fb

    -
    1



    at


    s

    =
    13

    TeV

    collected with the CMS detector at the LHC. The observed limit on the

    Z


    J
    /
    ψ

    γ

    decay branching fraction, assuming that the

    J
    /
    ψ

    meson is produced unpolarized, is

    1.4
    ×

    10

    -
    6



    at 95% confidence level, which corresponds to a rate higher than expected in the standard model by a factor of 15. For extreme-polarization scenarios, the observed limit changes from

    -
    13.6

    to

    +
    8.6
    %

    with respect to the unpolarized scenario. The observed upper limit on the branching fraction for

    H


    J
    /
    ψ

    γ

    where the

    J
    /
    ψ

    meson is assumed to be transversely polarized is

    7.6
    ×

    10

    -
    4



    , a factor of 260 larger than the standard model prediction. The results for the Higgs boson are combined with previous data from proton-proton collisions at


    s

    =
    8

    TeV

    to produce an observed upper limit on the branching fraction for

    H


    J
    /
    ψ

    γ

    that is a factor of 220 larger than the standard model value.
  19. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(1):20.
    PMID: 30872964 DOI: 10.1140/epjc/s10052-018-6482-9
    Measurements of inclusive isolated-photon and photon+jet production in proton-proton collisions at


    s

    =
    13

    TeV

    are presented. The analysis uses data collected by the CMS experiment in 2015, corresponding to an integrated luminosity of 2.26



    fb

    -
    1



    . The cross section for inclusive isolated photon production is measured as a function of the photon transverse energy in a fiducial region. The cross section for photon+jet production is measured as a function of the photon transverse energy in the same fiducial region with identical photon requirements and with the highest transverse momentum jet. All measurements are in agreement with predictions from next-to-leading-order perturbative QCD.
  20. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(5):421.
    PMID: 31178657 DOI: 10.1140/epjc/s10052-019-6909-y
    Combined measurements of the production and decay rates of the Higgs boson, as well as its couplings to vector bosons and fermions, are presented. The analysis uses the LHC proton-proton collision data set recorded with the CMS detector in 2016 at


    s

    =
    13


    Te



    , corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    . The combination is based on analyses targeting the five main Higgs boson production mechanisms (gluon fusion, vector boson fusion, and associated production with a
    W
    or
    Z
    boson, or a top quark-antiquark pair) and the following decay modes:

    H

    γ
    γ

    ,

    Z
    Z

    ,

    W
    W

    ,

    τ
    τ

    ,

    b
    b

    , and

    μ
    μ

    . Searches for invisible Higgs boson decays are also considered. The best-fit ratio of the signal yield to the standard model expectation is measured to be

    μ
    =
    1.17
    ±
    0.10

    , assuming a Higgs boson mass of

    125.09


    Ge



    . Additional results are given for various assumptions on the scaling behavior of the production and decay modes, including generic parametrizations based on ratios of cross sections and branching fractions or couplings. The results are compatible with the standard model predictions in all parametrizations considered. In addition, constraints are placed on various two Higgs doublet models.
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