MyMedR

The influence of sintering temperature on the porosity and strength of porous hydroxyapatite ceramics

Rusnah M, Andanastuti M, Idris B

Med J Malaysia, 2004 May;59 Suppl B:158-9.

The present paper reports on the influence of sintering temperature on the porosity and strength of porous hydroxyapatite (HA). HA powder was first prepared by the sol-gel precipitation method using calcium hydroxide and ortho-phosporic acid. The fine HA powder, measuring <50 microm was then mixed into a slurry with the addition of binder agent, being a mixture of sago and PVA. A small amount of sodium dodecyl sulphate was also used as a foaming agent. Porous HA samples were then prepared via slip casting technique. The surface morphology of the sintered samples was observed under scanning electron microscopy at 20 kV and the compositions were determined via SEM-EDX. A universal testing machine was used to determine the compaction strength of the sintered samples.

Hydroxapatite and tricalcium phosphate prepared by precipitation method

Cik Rohaida CH, Idris B, Mohd Reusmaazran Y, Rusnah M, Fadzley Izwan AM

Med J Malaysia, 2004 May;59 Suppl B:156-7.

PMID: 15468865

A mixture with different compositions of HA and TCP were synthesize in this work by precipitation method using Ca(NO3)2 4H2 and (NH4)2HPO4 as the starting materials. A mixture with HA and TCP phases in different ratios were produced. The powders were sintered from 1000 degrees C to 1250 degrees C. The phase compositions of the mixtures were then studied via XRD. This work shows that the pH value determines the different phase compositions of the HA-TCP mixture. Chemical analyses were carried out by FTIR. The microstructure was observed under SEM.

An endeavour from porous to 3D constructs bioceramics

Idris B, Rusnah M, Reusmaazran YM, Rohaida CH

Med J Malaysia, 2004 May;59 Suppl B:67-8.

PMID: 15468822

HAp physical investigation--the effect of sintering temperature

Azran YM, Idris B, Rusnah M, Rohaida CH

Med J Malaysia, 2004 May;59 Suppl B:79-80.

PMID: 15468828

The paper presents the effect of sintering temperature on the physical properties of porous hydroxyapatite (HAp In this study, the HAp was prepared using polymeric sponge techniques with different binder concentrations. The sintering process was carried out in air for temperature ranging from 1200 degrees C to 1600 degrees C. Different physical properties namely density and porosity were observed at different sintering temperatures. The HAp prepared with higher PVP binder showed a slightly decreased in apparent density with increasing sintering temperature, while those HAp prepared with lower PVP showed a slightly increase in apparent density with increasing sintering temperature. The total porosity was found to be approximately constant in the whole sintering temperature range. However, closed porosity decreases with increasing sintering temperature for HAp prepared by lower binder concentration. On the other hand, the HAp prepared by higher binder concentrations showed increasing closed porosity with increasing sintering temperature. Other features such as the influence of sintering temperatures on grain and strut would also be presented in this paper.

Microstructure and strength of extruded porous HA ceramics

Rusnah M, Andanastuti M, Idris B

Med J Malaysia, 2004 May;59 Suppl B:83-4.

PMID: 15468830

The paper discusses the influence of sintering temperature on the microstructure and strength of hydroxyapatite ceramics prepared using the extrusion process. The average pore diameters observed were in the range of approximately 150mm to 300mm whereas the compaction strength was found to be around 120-160 MPa.

History of neurosciences at the School of Medical Sciences, Universiti Sains Malaysia

Idris B, Sayuti S, Abdullah JM

J Clin Neurosci, 2007 Feb;14(2):148-52.

PMID: 17161289

Universiti Sains Malaysia is the only institution in Malaysia which incorporates all fields of the neurosciences under one roof. The integration of basic and clinical neurosciences has made it possible for this institution to become an excellent academic and research centre. This article describes the history, academic contributions and scientific progress of neurosciences at Universiti Sains Malaysia.

Fulltext Effects of sintering time on the physical and compositional properties of porous biphasic calcium phosphate foam

Cik Rohaida, C.H., Idris, B., Rusnah, M., Mohd Reusmaazran, Y., Narimah, A.B.

Journal of Nuclear and Related Technologies, 2009;2009(1):206-216.

MyJurnal

Phase composition of calcium phosphate ceramic is a characteristic directly related to the biological response of implants due to the differences in mechanical and biochemical properties of these compounds. The biodegradation rate of biphasic calcium phosphate (BCP) can be controlled by altering the HA to β-TCP ratios. In this study the crystalline phase evolution of BCP synthesized via precipitation from aqueous solution of (NH4)2PO4 titrated into heated solution of Ca (NO3)2 was evaluated. The resulting powder was fabricated into porous scaffold using polyurethane foam method. Bulk powders were sintered from 700 - 1400°C to determine the most significant sintering temperature to obtain a stable and well crystallize BCP phases. The porous scaffolds were then sintered at selected temperature and the effects of various sintering times from 5,7,9,11,13 and 15 h were investigated. Bulk powders were characterized by dilatometer, IR analysis and XRD and porous scaffolds were analyzed by XRD and SEMEdx. RIR method was performed to show that the HA to β-TCP ratios were increased with increasing of sintering time and reached the maximum HA value at 11h. It is found that, the possibilities to manipulate the HA to β-TCP ratios in BCP porous scaffold by just controlling the sintering time of the scaffold without controlling the starting powder characteristics.

Fulltext Role of high augmentation index in spontaneous intracerebral haemorrhage

Lee HK, Ghani AR, Awang MS, Sayuthi S, Idris B, Abdullah JM

Asian J Surg, 2010 Jan;33(1):42-50.

PMID: 20497882 DOI: 10.1016/S1015-9584(10)60008-5

Intracerebral haemorrhage (ICH) is the most disabling and least treatable form of stroke. Its risk factors include old age, hypertension, diabetes mellitus, hypercholesterolaemia, smoking and high alcohol intake, which are also associated with arterial stiffness. The aim of the present study was to determine the prognostic value of high augmentation index (AI), which is a surrogate marker of arterial stiffness, in patients with spontaneous ICH.

Fulltext Factors affecting the outcomes in children post-myelomeningocoele repair in northeastern peninsular malaysia

Idris B

Malays J Med Sci, 2011 Jan;18(1):52-9.

PMID: 22135574 MyJurnal

The present study aimed to evaluate the impact of multiple factors and outcomes (ambulatory function and sphincter function) on children with myelomeningocoele (MMC) following surgical repair.

Neuronavigation-guided endoscopic management of a pineal region tumour with obscured floor of the third ventricle: case report

Idris Z, Ghani AR, Idris B, Muzaimi M, Awang S, Pal HK, et al.

Minim Invasive Neurosurg, 2011 Jun;54(3):125-7.

PMID: 21863520 DOI: 10.1055/s-0031-1277198

Shunt surgery is frequently chosen to manage periventricular metastasis of pineal region tumours which obscured the floor of the third ventricle. However, this procedure falls short due to distant metastasis. Neuronavigation-guided endoscopic surgery offers a viable alternative.

The role of a high augmentation index in spontaneous intracerebral hemorrhage to prognosticate mortality

Keong LH, Ghani AR, Awang MS, Sayuthi S, Idris B, Abdullah JM

Acta Neurochir. Suppl., 2011;111:375-9.

PMID: 21725785 DOI: 10.1007/978-3-7091-0693-8_63

The aim of the study was to determine the prognostic value of a high augmentation index, which was a surrogate marker of arterial stiffness in patients with spontaneous intracerebral hemorrhage. The outcome was divided into two groups in which the following data were collected in a computer running SphygmoCor CvMS software version 8.2. Logistic regression analysis was carried out among significant variables to identify an independent predictor of 6-month outcome and mortality. Sixty patients were recruited into the study. Admission Glasgow Coma Scale score (OR, 0.7; 95% CI, 0.450-0.971; P=0.035), total white cell count (OR, 1.2; 95% CI, 1.028-1.453; P=0.023) and hematoma volume (OR, 1.1; 95% CI, 1.024-1.204; P=0.011) were found to be statistically significant for identifying poor 6-month outcome in multivariate analysis. Factors independently associated with mortality were a high augmentation index (OR, 8.6; 95% CI, 1.794-40.940; P=0.007) and midline shift (OR, 7.5; 95% CI, 1.809-31.004; P=0.005). Admission Glasgow Coma Scale score, total white cell count and hematoma volume were significant predictors for poor 6-month outcome, and a high augmentation index and midline shift were predictors for 6-month mortality in this study.

Fulltext Case report: a rare case of pediatric conus medularis glioblastoma multiforme

Gee TS, Ghani ARI, Idris B, Awang MS

Med J Malaysia, 2012 Aug;67(4):438-41.

PMID: 23082462 MyJurnal

Intraoperative Cerebrospinal Fluid Sample from First Ventriculoperitoneal Shunt Operation: Is it Indicated?

Zakaria Z, Idris B

Malays J Med Sci, 2013 Jul;20(4):102-3.

PMID: 24044006

Fulltext Neuronavigation-guided endoscopic and hodotopic approach to an arachnoid cyst

Idris Z, Nandrajog P, Abdullah JM, Ghani RI, Idris B

Surg Neurol Int, 2013;4:120.

PMID: 24083055 DOI: 10.4103/2152-7806.118492

BACKGROUND: Arachnoid cysts are intraarachnoid benign cystic lesions filled with cerebrospinal fluid and should be treated without incurring further morbidity to the patients.

CASE DESCRIPTION: The authors present a case of a 68-year-old elderly female with a large right fronto-parieto-temporal arachnoid cyst who has been suffering from mild left hemiparesis for the past 4 years and presented with sudden onset of seizures. The 3 Tesla MR system with diffusion tensor imaging (DTI) and MR tractography of the brain showed a large right fronto-parieto-temporal cystic lesion measuring 7 × 5 × 5 cm with a midline shift of 1 cm, suggestive of an arachnoid cyst with surrounding ipsilateral white matter projection pathways and inferior occipito-frontal fasciculus or inferior longitudinal white matter tracts. The cyst was successfully treated with neuronavigation-guided endoscopic and hodotopical approach to fenestrate the arachnoid cyst into the sylvian cistern, avoiding inadvertent injury to major white matter tracts portrayed by DTI. Postoperatively, a repeated computed tomography (CT) scan of the brain revealed a smaller arachnoid cyst with correction of the midline shift. The patient was weaned off from the ventilator and her hemiplegia improved gradually.

CONCLUSION: This case report emphasizes the value of neuronavigation-guided endoscopic and hodotopic approach to fenestrate the intra-axial arachnoid cyst.

Fulltext Pleomorphic xanthoastrocytoma in a case of tuberous sclerosis

Martin AG, Singh MS, Idris B, Abdullah JM

J Neurosci Rural Pract, 2014 Jul;5(3):258-60.

PMID: 25002765 DOI: 10.4103/0976-3147.133580

Tuberous sclerosis is a known phakomatosis and the associated finding of a subependymal giant cell astrocytoma is common with this disorder. A case of tuberous sclerosis with a finding not previously reported, i.e. that of a pleomorphic xanthoastrocytoma, is presented here.

Intraoperative fluorescence angiography for cerebrovascular neurosurgery in universiti sains malaysia

Kandasamy R, Idris Z, Idris B, Chin TY, Ghani AR, Abdullah JM

Malays J Med Sci, 2014 Jul;21(4):69-70.

PMID: 25977627

Fulltext Autonomy in refusing life saving interventions: religious and cultural misconceptions

van Rostenberghe H, Yong A, Mohd Zin F, Fuad MDF, Idris B, Tahir NA, et al.

Education in Medicine Journal, 2014;6(1):70-73.

MyJurnal

Autonomy is widely accepted to be the third pillar of medical ethics. However, if it comes to refusal of life saving treatments, some extra considerations are necessary, especially if decisions are made by surrogate decision makers. Four cases of problematic decision making are presented here, followed by a discussion about the cultural and religious misconceptions about the rights of surrogate decision makers.

Fulltext Deep Brain Stimulation (DBS) for Movement Disorders: An Experience in Hospital Universiti Sains Malaysia (HUSM) Involving 12 Patients

Hooi LL, Fitzrol DN, Rajapathy SK, Chin TY, Halim SA, Kandasamy R, et al.

Malays J Med Sci, 2017 Mar;24(2):87-93.

PMID: 28894408 MyJurnal DOI: 10.21315/mjms2017.24.2.11

Deep brain stimulation (DBS) was first introduced in 1987 to the developed world. As a developing country Malaysia begun its movement disorder program by doing ablation therapy using the Radionics system. Hospital Universiti Sains Malaysia a rural based teaching hospital had to take into consideration both health economics and outcomes in the area that it was providing neurosurgical care for when it initiated its Deep Brain Stimulation program. Most of the patients were from the low to medium social economic groups and could not afford payment for a DBS implant. We concentrated our DBS services to Parkinson's disease, Tourette's Syndrome and dystonia patients who had exhausted medical therapy. The case series of these patients and their follow-up are presented in this brief communication.

Fulltext Autologous Cranioplasty Post-Operative Surgical Site Infection: Does It Matter if the Bone Flaps were Stored and Handled Differently?

Cheah PP, Rosman AK, Cheang CK, Idris B

Malays J Med Sci, 2017 Dec;24(6):68-74.

PMID: 29379388 DOI: 10.21315/mjms2017.24.6.8

Fulltext Epilepsy Surgery in Hospital Universiti Sains Malaysia: Our Experiences since 2004

Yee AS, Tharakan J, Idris Z, Bhaskar S, Halim SA, Razak SA, et al.

Malays J Med Sci, 2017 Dec;24(6):97-102.

PMID: 29379392 DOI: 10.21315/mjms2017.24.6.12

Epilepsy surgery has been performed by a few centres in Malaysia, including Hospital Universiti Sains Malaysia (HUSM). To date, a total of 15 patients have undergone epilepsy surgery in HUSM. The epilepsy surgery included anterior temporal lobectomy (ATL) with amygdalohippocampectomy (AH) and Vagal nerve stimulation (VNS). The surgical outcomes of the patients were assessed using the International League Against Epilepsy (ILAE) outcome scale. The ILAE scores for patients who underwent ATL with AH were comparatively better than those who underwent VNS. One of the patient who underwent ATL with AH and frontal lesionectomy was found to have psychosis during follow up. Epilepsy surgery has proven to be an important treatment for medically resistant epilepsy. Thus it is important to raise public awareness regarding epilepsy and its treatment.

Displaying publications 1 - 20 of 23 in total