MyMedR

Fulltext Lymphangioma: Is intralesional bleomycin sclerotherapy effective?

Rozman Z, Thambidorai RR, Zaleha AM, Zakaria Z, Zulfiqar MA

Biomed Imaging Interv J, 2011 Jul-Sep;7(3):e18.

PMID: 22279495 MyJurnal DOI: 10.2349/biij.7.3.e18

This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of lymphangioma in children and to determine the incidence of complications in the treatment.

Fulltext Echocontrast cystosonography versus micturating cystourethrography in the detection of vesicoureteric reflux

Faizah M, Kanaheswari Y, Thambidorai C, Zulfiqar M

Biomed Imaging Interv J, 2011 Jan-Mar;7(1):e7.

PMID: 21655116 MyJurnal DOI: 10.2349/biij.7.1.e7

To compare echocontrast cystosonography (ECS) using in-vivo agitated saline with fluoroscopic micturating cystourethrography (MCU) in the detection and grading of vesicoureteric reflux (VUR).

Fulltext Precocious puberty in children: A review of imaging findings

Faizah M, Zuhanis A, Rahmah R, Raja A, Wu L, Dayang A, et al.

Biomed Imaging Interv J, 2012 Jan;8(1):e6.

PMID: 22970062 MyJurnal DOI: 10.2349/biij.8.1.e6

This review was aimed at determining the imaging findings in patients with precocious puberty.

Fulltext Musculoskeletal MRI protocol

Tan S, Suraya A, Sa'don S, Ruzi A, Zahiah M

Biomed Imaging Interv J, 2010 Apr-Jun;6(2):e16.

PMID: 21611037 MyJurnal DOI: 10.2349/biij.6.2.e16

The authors propose a musculoskeletal (MSK) magnetic resonance imaging (MRI) protocol using selected sequences for common orthopaedic indications. Selected sequences allow optimal visualisation of the indicated pathology while screening for other common conditions. The authors emphasise the need for standard positioning of the patient and standard orientation of scan planes to facilitate comparison with follow-up scans.

Fulltext Magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment for uterine fibroids

Abdullah B, Subramaniam R, Omar S, Wragg P, Ramli N, Wui A, et al.

Biomed Imaging Interv J, 2010 Apr-Jun;6(2):e15.

PMID: 21611036 MyJurnal DOI: 10.2349/biij.6.2.e15

Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as compared to myomectomy and hysterectomy. MRgFUS can be offered to a majority of patients suffering from symptomatic uterine fibroids. It has been suggested that the use of broader inclusion criteria as well as the mitigation techniques makes it possible to offer MRgFUS to a much larger subset of patients than previously believed. This paper will describe how MRgFUS treatment for uterine fibroids is performed at the University of Malaya Medical Centre, Kuala Lumpur, Malaysia.

Fulltext Phytobezoar: an unusual cause of intestinal obstruction

Teng H, Nawawi O, Ng K, Yik Y

Biomed Imaging Interv J, 2005 Jul;1(1):e4.

PMID: 21625276 MyJurnal DOI: 10.2349/biij.1.1.e4

Small bowel phytobezoars are rare and almost always obstructive. There have been previously reported cases of phytobezoars in the literature, however there are few reports on radiological findings for small bowel bezoars. Barium studies characteristically show an intraluminal filling defect of variable size that is not fixed to the bowel wall with barium filling the interstices giving a mottled appearance. On CT scan, the presence of a round or ovoid intraluminal mass with a 'mottled gas' pattern is believed to be pathognomonic. Since features on CT scans are characteristics and physical findings are of little assistance in the diagnosis of bezoar, the diagnostic value of CT needs to be emphasised.

Fulltext The South East Asian Federation of Organizations for Medical Physics (SEAFOMP): Its history and role in the ASEAN countries

Ng Kh, Wong J

Biomed Imaging Interv J, 2008 Apr;4(2):e21.

PMID: 21614324 DOI: 10.2349/biij.4.2.21

Informal discussion started in 1996 and the South East Asian Federation of Organizations for Medical Physics (SEAFOMP) was officially accepted as a regional chapter of the IOMP at the Chicago World Congress in 2000 with five member countries, namely Indonesia, Malaysia, Philippines, Singapore and Thailand. Professor Kwan-Hoong Ng served as the founding president until 2006. Brunei (2002) and Vietnam (2005) joined subsequently. We are very grateful to the founding members of SEAFOMP: Anchali Krisanachinda, Kwan-Hoong Ng, Agnette Peralta, Ratana Pirabul, Djarwani S Soejoko and Toh-Jui Wong.The objectives of SEAFOMP are to promote (i) co-operation and communication between medical physics organizations in the region; (ii) medical physics and related activities in the region; (iii) the advancement in status and standard of practice of the medical physics profession; (iv) to organize and/or sponsor international and regional conferences, meetings or courses; (v) to collaborate or affiliate with other scientific organizations.SEAFOMP has been organizing a series of congresses to promote scientific exchange and mutual support. The South East Asian Congress of Medical Physics (SEACOMP) series was held respectively in Kuala Lumpur (2001), Bangkok (2003), Kuala Lumpur (2004) and Jakarta (2006). The respective congress themes indicated the emphasis and status of development. The number of participants (countries in parentheses) was encouraging: 110 (17), 150 (16), 220 (23) and 126 (7).In honour of the late Professor John Cameron, an eponymous lecture was established. The inaugural John Cameron Lecture was delivered by Professor Willi Kalender in 2004. His lecture was titled "Recent Developments in Volume CT Scanning".

Fulltext Glioblastoma multiforme: a rare manifestation of extensive liver and bone metastases

Robert M, Wastie M

Biomed Imaging Interv J, 2008 Jan;4(1):e3.

PMID: 21614314 MyJurnal DOI: 10.2349/biij.4.1.e3

Glioblastoma multiforme (GBM) is the most aggressive form of primary brain tumours known collectively as gliomas. Gliomas are graded by their microscopic appearance. As a rule, their behaviour can be predicted from histology: Grade I (pilocytic astrocytomas) and Grade II (benign astrocytomas) tumours are of low grade and grow slowly over many years. Grade IV tumours (GBM) are the most aggressive and, unfortunately, also the most common in humans, growing rapidly, invading and altering brain function. These tumours arise from the supporting glial cells of the brain during childhood and in adulthood.These growths do not spread throughout the body like other forms of cancer, but cause symptoms by invading the brain. Untreated GBMs are rapidly lethal. Most patients with GBM die of their disease in less than a year and none have long term survival.Extracranial metastases from GBM are extremely rare, with a reported frequency of only 0.44% because of the absence of lymphatics in the brain and the difficulty of tumours to penetrate blood vessels. A case of glioblastoma multiforme with the rare features of extensive liver and bone metastases is presented in this paper.

Fulltext Imaging features of fungal infection in immuno-suppressed patients in a local ward outbreak

Ahmad Sarji S, Wan Abdullah W, Wastie M

Biomed Imaging Interv J, 2006 Apr;2(2):e21.

PMID: 21614228 DOI: 10.2349/biij.2.2.e21

To examine the role of imaging in diagnosing and assessing fungal infections in paediatric patients undergoing chemotherapy in a facility, which had high fungal air contamination due to adjacent building construction work.

Fulltext Gartner duct cyst in pregnancy presenting as a prolapsing pelvic mass

Arumugam A, Kumar G, Si L, Vijayananthan A

Biomed Imaging Interv J, 2007 Oct;3(4):e46.

PMID: 21614298 MyJurnal DOI: 10.2349/biij.3.4.e46

Gartner duct cysts are the remnants of the Wolffian duct and they are rarely seen in adulthood. We present a case of a pregnant patient with a prolapsing vaginal mass. A diagnosis of Gartner duct cyst was made after MRI was performed. The Gartner duct cyst was drained when the patient went into labour allowing vaginal delivery to be performed.

Fulltext Optimal slice thickness for cone-beam CT with on-board imager

Seet K, Barghi A, Yartsev S, Van Dyk J

Biomed Imaging Interv J, 2010 07 01;6(3):e31.

PMID: 21611047 DOI: 10.2349/biij.6.3.e31

PURPOSE: To find the optimal slice thickness (Δτ) setting for patient registration with kilovoltage cone-beam CT (kVCBCT) on the Varian On Board Imager (OBI) system by investigating the relationship of slice thickness to automatic registration accuracy and contrast-to-noise ratio.

MATERIALS AND METHOD: Automatic registration was performed on kVCBCT studies of the head and pelvis of a RANDO anthropomorphic phantom. Images were reconstructed with 1.0 ≤ Δτ (mm) ≤ 5.0 at 1.0 mm increments. The phantoms were offset by a known amount, and the suggested shifts were compared to the known shifts by calculating the residual error. A uniform cylindrical phantom with cylindrical inserts of various known CT numbers was scanned with kVCBCT at 1.0 ≤ Δτ (mm) ≤ 5.0 at increments of 0.5 mm. The contrast-to-noise ratios for the inserts were measured at each Δτ.

RESULTS: For the planning CT slice thickness used in this study, there was no significant difference in residual error below a threshold equal to the planning CT slice thickness. For Δτ > 3.0 mm, residual error increased for both the head and pelvis phantom studies. The contrast-to-noise ratio is proportional to slice thickness until Δτ = 2.5 mm. Beyond this point, the contrast-to-noise ratio was not affected by Δτ.

CONCLUSION: Automatic registration accuracy is greatest when 1.0 ≤ Δτ (mm) ≤ 3.0 is used. Contrast-to-noise ratio is optimal for the 2.5 ≤ Δτ (mm) ≤ 5.0 range. Therefore 2.5 ≤ Δτ (mm) ≤ 3.0 is recommended for kVCBCT patient registration where the planning CT is 3.0 mm.

Fulltext Malignant ovarian mixed germ cell tumour: a rare combination

Koshy M, Vijayananthan A, Vadiveloo V

Biomed Imaging Interv J, 2005 Oct;1(2):e10.

PMID: 21625278 MyJurnal DOI: 10.2349/biij.1.2.e10

Ovarian germ cell tumours are very rare and affect mainly young girls and women. Due to this, the conservation of reproductive potential is of great concern. One of the most remarkable advances in oncology is in the treatment of malignant ovarian germ cell tumours. Two histological groups are distinguished: dygerminomas, equivalent to testicular seminomas, and non-dysgerminomatous tumours. We report a case of a 30-year-old nulliparous woman who presented with persistent per vaginal bleeding and was found to have a malignant mixed germ cell tumour comprising of both embryonal carcinoma and choriocarcinoma.

Fulltext From ultrasound images to block based region motion estimation

Ranjit S, Sim K, Besar R, Tso C

Biomed Imaging Interv J, 2009 Jul;5(3):e32.

PMID: 21611059 MyJurnal DOI: 10.2349/biij.5.3.e32

By applying a hexagon-diamond search (HDS) method to an ultrasound image, the path of an object is able to be monitored by extracting images into macro-blocks, thereby achieving image redundancy is reduced from one frame to another, and also ascertaining the motion vector within the parameters searched. The HDS algorithm uses six search points to form the six sides of the hexagon pattern, a centre point, and a further four search points to create diamond pattern within the hexagon that clarifies the focus of the subject area.

Fulltext Radiofrequency ablation of a misdiagnosed Brodie's abscess

Chan R, Abdullah B, Aik S, Tok Ch

Biomed Imaging Interv J, 2011 Apr;7(2):e17.

PMID: 22291860 DOI: 10.2349/biij.7.2.e17

Radiofrequency ablation (RFA) therapy is recognised as a safe and effective treatment option for osteoid osteoma. This case report describes a 27-year-old man who underwent computed tomography (CT)-guided percutaneous RFA for a femoral osteoid osteoma, which was diagnosed based on his clinical presentation and CT findings. The patient developed worsening symptoms complicated by osteomyelitis after the procedure. His clinical progression and subsequent MRI findings had led to a revised diagnosis of a Brodie's abscess, which was further supported by the eventual resolution of his symptoms following a combination of antibiotics treatment and surgical irrigations. This case report illustrates the unusual MRI features of osteomyelitis mimicking soft tissue tumours following RFA of a misdiagnosed Brodie's abscess and highlights the importance of a confirmatory histopathological diagnosis for an osteoid osteoma prior to treatment.

Fulltext Increasing the speed of medical image processing in MatLab

Bister M, Yap C, Ng Kh, Tok Ch

Biomed Imaging Interv J, 2007 Jan;3(1):e9.

PMID: 21614269 DOI: 10.2349/biij.3.1.e9

MatLab(®) has often been considered an excellent environment for fast algorithm development but is generally perceived as slow and hence not fit for routine medical image processing, where large data sets are now available e.g., high-resolution CT image sets with typically hundreds of 512x512 slices. Yet, with proper programming practices - vectorization, pre-allocation and specialization - applications in MatLab(®) can run as fast as in C language. In this article, this point is illustrated with fast implementations of bilinear interpolation, watershed segmentation and volume rendering.

Fulltext Pelvic aneurysmal bone cyst

Sharifah M, Nurhazla H, Suraya A, Tan S

Biomed Imaging Interv J, 2011 Oct;7(4):e24.

PMID: 22279501 MyJurnal DOI: 10.2349/biij.7.4.24

This paper describes an extremely rare case of a huge aneurysmal bone cyst (ABC) in the pelvis, occurring in the patient's 5(th) decade of life. The patient presented with a history of painless huge pelvic mass for 10 years. Plain radiograph and computed tomography showed huge expansile lytic lesion arising from the right iliac bone. A biopsy was performed and histology confirmed diagnosis of aneurysmal bone cyst. Unfortunately, the patient succumbed to profuse bleeding from the tumour.

Fulltext Image file formats

Tan L

Biomed Imaging Interv J, 2006 Jan;2(1):e6.

PMID: 21614221 DOI: 10.2349/biij.2.1.e6

Fulltext CT perfusion as a useful tool in the evaluation of leuko-araiosis

Ramli N, Ho K, Nawawi O, Chong H, Tan C

Biomed Imaging Interv J, 2006 Apr;2(2):e16.

PMID: 21614226 DOI: 10.2349/biij.2.2.e16

BACKGROUND: Leuko-araiosis (LA) and dementia are common geriatric conditions but their pathogenesis and clinical significance are not completely understood. An evaluation of CT perfusion (CTP) in both these conditions can further enhance the understanding of these diseases.

METHODS: Twenty-one patients with LA and 21 age-matched controls were studied with CTP and assessed for their cognitive function. The subjects were classified into four groups: Group 1, with LA (n = 21); Group 2, without LA (n = 21); Group 3, with dementia (n = 7); Group 4, without dementia (n = 11). The mean cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) values were compared between groups 1 and 2, while mean CBF values were compared between groups 3 and 4.

RESULTS: Mean white matter CBF was considerably reduced in patients with LA in the frontal region by 42% (p = 0.000), basal ganglia by 37% (p = 0.000) and occipital region by 18% (p = 0.019). The mean white matter CBV was reduced in patients with LA in the frontal region by 36% (p = 0.000) and basal ganglia by 28% (p = 0.017). The mean white matter CBF was dramatically reduced in patients with dementia in the frontal region by 44% (p = 0.000), basal ganglia by 32% (p = 0.038) and occipital regions by 24% (p = 0.001).

CONCLUSION: The CTP showed reduced white matter CBF and CBV in patients with LA. This is consistent with chronic ischemia as the pathogenesis of LA. The CTP is also a potentially important technique in the diagnosis and management of dementia, because of its ability to reveal cerebral hypoperfusion.

Fulltext Radionuclide therapy of hepatocellular carcinoma

Sundram F

Biomed Imaging Interv J, 2006 Jul;2(3):e40.

PMID: 21614248 MyJurnal DOI: 10.2349/biij.2.3.e40

Hepatocellular carcinoma (HCC) is a malignant tumour of the hepatocyte. It is a common malignancy worldwide and causes almost half a million deaths annually. Asia is a high risk area. Although surgery (hepatectomy or liver transplantation) is the main form of curative treatment, the majority of patients are not eligible for surgery due to extent of tumour and dysfunction of liver. Radiopharmaceuticals used for transarterial treatment of HCC were Yttrium-90 microspheres, Iodine-131 lipiodol, Rhenium-188 lipiodol, and Holmium-166 Chitosan complex. Yittrium-90 microspheres are glass or resin microspheres of mean sphere diameter of 20 to 30 micrometre. The activity administered was about 4 GBq. Reported response rate was about 20%, and median survival was 54 weeks. On inoperable tumours, reported objective response of I-131 lipiodol was 40 to 70%, and median survival was six to nine months. It showed efficacy similar to TACE. In adjuvant treatment following curative resection of HCC, reported three year survival was 86% compared with 46% for the control group. The administered activity in both adjuvant and inoperable HCC was about 2 GBq (55 mCi). Rhenium-188 lipiodol is a new radioconjugate, and using it we treated 70 patients with inoperable HCC. This treatment was a part of a multi-centre trial sponsored by the International Atomic Energy Agency. Partial response was obtained in 17% of cases, while 49% had stable disease at three months, and 34% showed disease progression. In terms of survival, 19% survived one year, 60% for six months, and 90% for three months. The mean activity was about 4.6 GBq (124 mCi). This method was safe and free from adverse effects.

Fulltext Clinical use of PET/CT in thyroid cancer diagnosis and management

Sundram F

Biomed Imaging Interv J, 2006 Oct;2(4):e56.

PMID: 21614336 MyJurnal DOI: 10.2349/biij.2.4.e56

The incidence of thyroid cancer is low, but when it occurs, it is mainly of the papillary histopathological type. Although PET/CT has a limited role in the diagnosis, it plays a significant role in the overall post-surgery management of a patient with thyroid cancer. This follow-up role is important, especially in patients with elevated serum thyroglobulin, but negative radioiodine whole body scans. There is increasing evidence that PET/CT should be a part of routine care in the Tg positive Radioiodine scan negative patient.

Displaying publications 1 - 20 of 104 in total