MATERIALS AND METHODS: A systematic search of the literature was conducted on electronic databases of PubMed/MEDLINE, EBSCO, Cochrane library, Google, and Google Scholar from January 2011 to April 2021 to determine studies that reported warfarin adherence on patients with atrial fibrillation.

RESULTS: Out of 1429 titles and abstracts were retrieved, 12 studies fulfilled and met the inclusion criteria. From the included studies, two were carried out in Brazil and one from the following nations: Libya, Jordan, Iran, KSA, Canada, Malaysia, Bahrain, UAE, Singapore, and the USA. The study designs identified were cross-section, retrospective, and prospective studies. Warfarin adherence was influenced by multiple causes, including pharmaceutical services, the number of medications, and warfarin knowledge regarding anticoagulation control. Warfarin adherence illustrates its positive association with TTR and INR as a measure of anticoagulation control.

MATERIALS AND METHODS: Data were gathered through open-ended interviews among nine participants. And to complement the data, particularly about the public's opinions toward the transgender, a focus group discussion (FGD) was held among four participants.

RESULTS: The findings indicate that the transgender community often faces social discrimination due to the social stigma towards them. Thus, the treatment should be more on psychological therapies, family education, community awareness, and social activism that are needed to realign the transgender to the right track.

MATERIALS AND METHODS: This review has been compiled using relevant keywords and a thorough web search utilising PubMed, ScienceDirect, GoogleScholar, Scopus, MEDLINE, and SpringerLink.

RESULTS: Conventional medicines that target various biological processes have a significant negative impact on normal cells. As a result, targeted therapies are required, which include the use of small-molecule inhibitors and monoclonal antibodies to target cancer cell surface receptors, growth factors, and other proteins involved in disease progression. In this review, we summarize the known targeted PaCa therapies, which include inhibitors of the KRAS, mTOR, and PI3K/AKT signaling pathways, as well as PARP, hedgehog, EGFR/ErbB, and TGF-β signaling pathways, along with inhibitors of the neurotrophic tropomyosin receptor kinase (NTRK).

MATERIALS AND METHODS: We investigated Google Trends® for popular search relating to medication errors, risk management and shift work. Relative search volumes (RSVs) were evaluated from 2008 to 2018. A comparison between RSV curves related to medication errors, risk management and shift work was carried out. Then, we compared the world to Italian search.

RESULTS: RSVs were persistently higher for risk management than for medication errors (mean RSVs 069 vs. 48%) and RSVs were stably higher for medication errors than shift work (mean RSVs 48 vs. 22%). In Italy, RSVs were much lower compared to the rest of the world, and RSVs for medication errors during the study period were negligible. Mean RSVs for risk management and shift work were 3 and 25%, respectively. RSVs related to medication errors and clinical risk management were correlated (r=0.520, p<0.0001).