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  1. Chua, Philip Yi Shean, Lee, Sue Laine, Tow, Zhen Jiang, Mantok, Richmund, Muhamad Khairul Hawari Muhamad Nor, Dorairaja, Lavena, et al.
    Int J Public Health Res, 2013;3(1):223-231.
    MyJurnal
    Rapid Rural Appraisal (RRA) is a systematic, semi-structured activity carried out in the field by a multidisciplinary team that is designed to obtain new information and hypotheses about rural life. This article reports the results of an RRA conducted in Kampung Paris 1 (KGP1), Kinabatangan, Sabah under the Annual Health Promotion Program of the School of Medicine, Universiti Malaysia Sabah. A systematic random sampling was used to recruit the villagers and data was obtained through compilation of pre-existing data, field observation, structured interviews with key informants and villagers. Cardiorespiratory diseases were prevalent in KGP1. Common water sources such as rain water collected in dug wells in KGP1 were unhygienic. Dangerous toxic fumes were produced by the burning of municipal wastes nearby village houses. The villagers of KGP1 were exposed to various farm animals, which may harbor zoonoses. Health care services are limited in KGP1. Villagers who were not poor (>RM897) represented 48% of the population, followed by the poor (RM503-897), 20% and the hardcore poor (1.00 person per bedroom. Poor water hygiene, polluted air from open burning, exposure to farm animals, poverty, poor education, overcrowding and inadequate health care services were among the few possible factors affecting the health of villagers in KGP1. Formal rigorous research should be conducted in the future to facilitate specific health interventions in areas of need such as KGP1.
  2. Fateh Addin Nejm Addin Al-Emad, Zaleha Md. Isa
    Int J Public Health Res, 2017;7(1):783-790.
    MyJurnal
    BACKGROUND: The aim of the study was to assess the knowledge and attitude of secondary school students in Sana'a Yemen related to exposure to second-hand smoking.
    METHODS: A cross-sectional study was conducted in Sana'a city. The total sample size was 336 students in which 63 were males and 273 were females. These students were stratified random sampling . Data were collected by using Questionnaire comprising of 3 parts: Part 1- consists of socio-demographic data. Part 2- consists of the knowledge regarding smoking and second-hand smoking and Part 3-consists of adolescents' attitude in relation to second-hand smoking.
    RESULTS: Out of 336 students, majority were between 14-18 years old (75.9%), males (81.2%) , (55.7%)of them was fathers' occupation private employee and low educated mother was (86.3%).The students who do not have smoking habit were (94.3%),and those who do not have friends with the habit of smoking was (57.4%). (57.10) having some one else at home who smokes beside them .The reaction of non printed mass media for SHS warning was (83.3%) . The exposed to smoke out door was (60.1%) . In this study, the majority of students had inadequate knowledge about the second-hand smoke was (52.7%). A higher percentage of students who had unfavorable attitudes toward secondhand smoke was(86.6%).
    CONCLUSION: We concluded that The level of knowledge and attitude about the second-hand smoke is relatively low among the secondary school student in Sana'a Yemen .The finding of this study emphasized the need of effective awareness programs to increase level of consciousness and knowledge regarding SHS. Keywords: Second-hand Smoking, Secondary School, Adolescent, Sana'a .
  3. Mohammed Ali Mohammed Al-Wesabi, Zaleha Md Isa
    Int J Public Health Res, 2015;5(1):560-568.
    MyJurnal
    Introduction There is a strong and increased worldwide interest on the aspects of
    prevention of oral disease and oral health promotion in dental education.
    However, some studies imply that dental students are not knowledgeable
    enough in this issue. This study aimed to evaluate the knowledge of, attitude
    towards and practice on preventive dentistry among senior dental students in
    Yemen.

    Methods Self-administered questionnaires were distributed among senior dental
    students in six dental schools in Yemen. The questionnaire obtained personal
    information, and questions about knowledge on preventive dental care,
    attitudes towards and practice on preventive dentistry.

    Results Among 346 students who filled the questionnaire, a total of 91.6% has good
    knowledge about fissure sealant effectiveness, only 34.7% knows about the
    importance of fluoride toothpaste compared to brushing technique in
    preventing caries, with significant gender difference (p=0.005). Odds of good
    knowledge among non-Qat chewers was 1.9 (95%CI: 1.26-4.42).
    Multivariable regression analysis indicated that female gender was associated
    with higher positive attitudes (OR: 2.03, 95%CI:1.21-3.36,p=0.007).
    Attitudes were significantly associated with Qat chewing (OR = 1.95,
    95%CI: 1.04-3.66, p=0.03), type of university (OR = 0.59, 95%CI: 0.36-0.94,
    p=0.02), and mothers' level of education (OR = 1.91, 95%CI: 1.05-3.47,
    p=0.03). There was a high percentage of competency in practicing preventive
    measures among students (80.9%).

    Conclusions Dental education should emphasize the overall aspects of preventive dentistry
    with early exposure of preventive dental training in order to improve
    students' knowledge and attitudes and consequently practice on preventive
    care.
  4. Yuhanif Yusof, Anisah Che Ngah, Zaki Morad Mohamad Zaher
    Int J Public Health Res, 2014;4(1):384-390.
    MyJurnal
    Introduction The aim of this study was to examine the aspect of information disclosure by doctor-investigator during the process of obtaining informed consent in clinical trials.
    Methods This research employed a mixed-method data collection that is library research and interview. A qualitative methodology and analysis were used in an open-ended, face-to-face interviews with 17 patient-subjects. The interview questions were based on information that needed to be disclosed to patient-subjects during the process of obtaining informed consent. Each interview took place in Kajang Hospital and National Heart Institute and lasted 25-30 minutes. Interviews were conducted in Bahasa Melayu and English. The interviews were tape-recorded, and the main points from the interviews were jotted down to ensure that all information was adequately gathered. Interviewed occurred in Kajang Hospital and National Heart Institute. The participants were patients who had been referred to the Kajang Hospital and National Heart Institute. They were recruited (8 from Kajang Hospital and 9 from National Heart Institute) by their own doctors to participate in a study to evaluate the safety and effectiveness of the investigational stent after been diagnosed with coronary artery disease and also in a study to investigate drug for antidepressant. respectively.
    Results The study revealed that doctor-investigators fail to disclose full information to patient-subjects. Instead, doctor-investigators only disclosed information which they thought were necessary for the patient-subjects to know. The study also showed that there were doctor-investigators who did not disclose information at all to the patient-subjects.
    Conclusions This study implies that the aspect of information disclosure in the process of obtaining informed consent in clinical trials is rather poor and did not fulfill the criterion of good medical practice. A random monitoring task to be conducted by the research ethics commitees during the informed consent process is suggested.
  5. Ling, W.W., Ling, L.P., Chin, Z.H., Wong, I.T., Wong, A.Y., Nasef, A., et al.
    Int J Public Health Res, 2011;1(2):152-162.
    MyJurnal
    Intake and Output (I/O) records in hospitals were often found to be incomplete and illegible. The form used to record I/O is not user-friendly - i.e., they feature miniscule boxes, 'total' lines that do not correspond with shift changes and lack of instructions. Complaints often received from Specialists & Doctors regarding calculation errors or no totalling of I/O. Moreover, Nursing Sisters objective rounds often saw incompleteness of I/O chart. This study aims to identify the types of mistakes in recording the existing I/O chart. The second aim is to find out whether shift totalling of I/O chart helps in reducing mistakes. We try to determine whether the identified mistakes were repeated in the new I/O Chart. This study was conducted from October till December 2010 in 9 selected wards in Sibu Hospital. Data collection was divided into 3 phases. A pre-implementation audit using a checklist was carried out. The compliance rate of completeness of documentation of I/O Chart was 63%. A one month trial of new I/O chart was being done in the selected 9 wards. Post implementation audit showed a significant improvement of compliance rate (88%). Feedback from health care workers (N=110) showed that, 89% of doctors (n=17) and 60% of nurses (n=93) in the sample prefer to use the new format as more practical and relevant to the changing shift of nurses and doctors' ward round. It is suggested to implement the new format to increase compliance rate of documentation of I/O charting. Briefing should be given to nurses periodically and the new format should be introduced to nursing students in nursing colleges.
  6. Rozita Hod, Hidayatulfathi Othman, Nurul Azimah Jemain, Mazrura Sahani, Kamarulismail Udin, Zainudin Mohd Ali, et al.
    Int J Public Health Res, 2013;3(2):347-352.
    MyJurnal
    Dengue is a disease propagated by vectors namely Aedes spp. mosquitoes. One of the effective approaches to control dengue is through integrated vector management and intervention programs. COMBI or Communication for Behavioral Impact is a strategic approach to control the Aedes population as well as dengue cases. This study was conducted at Taman Desa Kolej, Nilai, Negeri Sembilan, an suburban residential area to determine the effectiveness of COMBI, by using questionnaire and entomological survey as well as implementation of an intervention program. We carried out activities such as the establishment of COMBI promoter team, clean up events, talk shows with the residential community and distributed pamphlets containing information about dengue. Results indicated significant difference (p
  7. Hasnor Hadi Asim, Normawati Ahmad, Abu Bakar Rahman, Nik Mansor Ibrahim, Mohd Nasir Abdullah, Md Sabtuah Royali, et al.
    Int J Public Health Res, 2017;7(2):807-813.
    MyJurnal
    Introduction Tong Nibong is a Bidayuh village located at Sarawak Kalimantan border.
    Since the year 2004 to 2009, a total of 537 cases of malaria were recorded in
    Serian District of which 14 cases were reported from Kampung Tong
    Nibong. Community empowerment programme for malaria infection
    prevention showed tremendous improvement in implementation. This
    intervention study aims to gauge the effectiveness of community
    empowerment approach in malaria elimination programme in Kampung Tong
    Nibong Serian.
    Methods An intervention study was conducted with pre and post data collection. Data
    was collected using validated questionnaire by face to face interview.
    Universal sampling method was used to select respondents from head of
    household and post data was collected after intervention activities were
    carried out within a year of study period.
    Results The study showed significant difference on level of knowledge of
    respondents on vector of malaria between pre and post data with a P < 0.05.
    There was significant difference between pre and post data on practices on
    control and prevention of malaria with a P < 0.05. The same goes to level of
    positive attitude of respondents towards malaria control.
    Conclusions In conclusion, the study can be considered successful because there is
    significant difference in knowledge, attitude and practice among the
    respondents between pre and post data. This indicates that community
    empowerment (voluntary participation) measures can be implemented in high
    risk or endemic areas where malaria is a persistent problem to the community
    and health institutions faces many limiting factors.
  8. Yong, Kang Cheah
    Int J Public Health Res, 2014;4(1):391-398.
    MyJurnal
    Introduction. In light of the important role of health-promoting expenditure in health, the objective of this study was to investigate the socio-demographic determinants of health-promoting expenditure such as purchase of medical equipment and services, food supplements and health education services and products among Malaysian adults.
    Methods Third National Health and Morbidity Survey (NHMS III) consisting of 28771 observations was used for analysis. It was the latest nationally representative cross-sectional population-based survey conducted by the Ministry of Health Malaysia from April 2006 to January 2007. A censored regression model
    (Tobit) was applied to examine the factors affecting health-promoting expenditure.
    Results The results showed that age, income, gender, ethnicity, education, marital status, employment status and location of residence were able to affect health promoting expenditure. In particular, individuals who were younger, poor, males, Indian/others, less educated, unmarried, unemployed and residing in rural areas tended to spend less money on health promotion compared to others.
    Conclusions This study reached a conclusion that socio-demographic factors were significantly associated with individual’s preferences for health promotion. Therefore, the government should devote its attention to these factors when
    formulating nationwide health policies.
    Study name: National Health and Morbidity Survey III (NHMS-2006)
  9. William Cairns Steward Smith
    Int J Public Health Res, 2014;4(1):425-430.
    MyJurnal
    Introduction Cardiovascular diseases are a major component of non-communicable
    diseases and include coronary heart disease, stroke and peripheral vascular
    disease. Public health strategies to address cardiovascular disease require
    three elements: surveillance, health promotion, and individual health care.

    Methods Surveillance includes monitoring of mortality and morbidity as well as
    surveys to monitor risk factors levels in the community. Data on mortality
    from cardiovascular diseases are readily available and analysed by age and
    sex specific rates looking are secular trends, geographical and ethnical group
    variations and international comparisons. However many deaths from
    cardiovascular disease occur suddenly and the cause of death may be
    registered without autopsy or any other validation. Cardiovascular morbidity
    information is more difficult to collate and interpret as it is closely related to
    availability and access to health care. Periodic surveys of cardiovascular risk
    factors are essential in monitoring the underlying trends in blood pressure,
    smoking, cholesterol, obesity, and diabetes as they predict future trends, and
    support planning for prevention and healthcare.

    Results Prevention and health promotion activities are informed by the levels and
    trends in cardiovascular disease and its risk factors. There has been debate
    about population health promotion and individual health care strategies, but
    both are necessary. Cigarette smoking, nutrition and physical exercise are the
    main behaviours to be addressed but these are complex and require
    multifaceted approaches. Education alone is insufficient to change health
    behaviours and health promotion needs to look to changing attitudes.
    Legislation, taxation and other fiscal interventions have been shown to be
    effective however these can be difficult for legislators as there are other
    competing interests, particularly in the area of nutrition and tobacco. Creating
    health promoting environments that make healthy behaviour choices easier
    can be beneficial.

    Conclusions Health care interventions are also effective in reducing the burden of
    cardiovascular disease. A balanced approach of health promotion and
    individual health care is recommended in the development of a strategy for
    cardiovascular disease.
  10. Norfazillah Ab Manan, Rozita Hod, Hanizah Mohd Yusoff, Mazrura Sahani, Rosnah Ismail, Wan Rozita Wan Mahiyuddin
    Int J Public Health Res, 2016;6(1):707-712.
    MyJurnal
    Air pollution has been widely known to have an influence on health of the general population.
    Air pollution can result from natural causes, human activities and transboundary air pollution.
    Weather and climate play crucial role in determining the pattern of air quality. In recent years,
    air pollution and recurrent episodes of haze has become a major concern in Malaysia.
    Surveillance data on concentrations of main air pollutants such as carbon dioxide, (CO2),
    Nitrogen Dioxide (NO2), Ozone (O3), sulphur dioxide (SO2) and particulate matter (PM10)
    were found to be higher during the haze days and this may have an impact on health of the
    community as reflected by an increase in hospital admissions particularly the respiratory and
    cardiovascular diseases.
  11. Anuar Ithnin, Kong, Dinnee, Venkataraman, Saraswathy
    Int J Public Health Res, 2012;2(2):137-143.
    MyJurnal
    Carpal tunnel syndrome (CTS) is a hand disorder which indicates the presence of symptoms such as pain, numbness, and muscle weakness among the patient. CTS is an occupational related disorder which can occur in any profession. However, it can be prevented and managed. The aims of the research were to determine the prevalence of acquiring CTS among nurses who worked in the wards and occupational risk factors involving the upper limbs during nursing tasks performance. The specific aims were to determine the relationship between the prevalence of acquiring CTS and individual factors (age, gender, race, educational level, duration of work and medical history), relationship between the prevalence of acquiring CTS and occupational risk factors in nursing tasks. Nurses profession was chosen as they are performing multitask involving upper limbs especially the wrist joints. Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) was used to determine the level of severity in CTS. Occupational risk factors were assessed by using the Rapid Upper Limb Assessment (RULA). This research was a cross sectional mode which was carried out at a government university medical centre from November through December 2010. Eighty nurses were involved in the research. The respondents were required to fill in the socio-demographic information sheet. Those having CTS were required to fill in the BCTQ. Assessments were performed by observing of the job activity through RULA. The results showed that the prevalence for nurses acquiring CTS is 7.5%. The RULA assessment also indicated that the risk factor was in the highest level with a score of 7. No relationship was shown between the prevalence of CTS and race, gender, educational level and medical history. Significant relationship was indicated by the prevalence of CTS and occupational risk factors. In conclusion, a significant prevalence of CTS related to age of more than 30 years old, Malay races compared to Indian, working experience of more than 10 years and respondents with right hand dominant. Occupational risk factors also indicated among the active nurses. Therefore, it is important for us to modify the work environment, work flow, work methodology and ergonomic factors in order to prevent the nurses from acquiring CTS. Furthermore, education about the condition of CTS should be implemented and reinforced especially among the higher risk nurses.
  12. Khor, Poh Yen, Norshidah Harun, Fazreenizam Ishak, Nur Aimy Iryany Mohd Anuar, Noraini Abdul Karim, Aqirah Azman, et al.
    Int J Public Health Res, 2012;2(1):80-84.
    MyJurnal
    Accepted 13 January 2012.
    Introduction The purpose of this study is to explore the reasons of Shisha smoking among teenagers in Ipoh, Perak.
    Methods Data was collected using in-depth face to face interview. Purposive convenient sampling was used to select volunteer respondents from one of the Shisha restaurant located at Ipoh. The interviews were conducted for 15-20 minutes, recorded using video tape. The data obtained was transcribed and coded for the purpose of thematic analysis.
    Results All respondents were influenced by peers in their first attempt in Shisha smoking. Other reasons attracting them to continue smoking Shisha include appealing smell and the flavoured taste of Shisha, easy to access, perceived that Shisha was not addictive and its’ cheaper price. In terms of perception on health risk, all respondents believed that Shisha was less harmful compared to cigarette smoking.
    Conclusions More educational programme, health talk about risk of Shisha should be developed and conducted to rectify the misconception about health risk of Shisha smoking. The target population should be focus on male teenagers who smoke Shisha in order to control the widespread Shisha smoking in Malaysia.
  13. Toh, Teck Hock
    Int J Public Health Res, 2011;1(2):57-65.
    MyJurnal
    Developmental disabilities in young children are common, and the prevalence is estimated as high as 0.1-1.75% in the children population for each disabilities. With increasing awareness and health expectation, more children with Developmental disabilities are presenting to health care professionals, and at earlier age. Literatures also suggested the importance of early intervention programme in determining the outcome of this group of children. Therefore, it is vital for health professionals who have direct contact with young children are competent in detecting children with possible Developmental disabilities, and have the basic knowledge about some of the common disorders in order to discuss the issues with the parents. It is also important to work with the various resources available in the local community, such as non-governmental organisations for children with special needs, schools offering special education programmes and inclusive classes, and the allied health who provide cares to this group of young children and their family. A lot of information are also available online, and may be offered to help parents gaining more understanding regarding these Developmental disabilities.
  14. Ling, Sui Hui, Chua, Soh Yian, Habsah Razak, Muhamad Rais Abdullah, Wong, See Chang, Toh, Teck Hock
    Int J Public Health Res, 2011;1(2):146-151.
    MyJurnal
    Introduction Children with cerebral palsy (CP) are often prescribed Rehabilitation and Seating Systems (RSS) to assist in daily activities, posture improvement and prevention of muscular-skeletal complications. In Sarawak, a special project to produce RSS was started under a partnership of a Japanese physiotherapist, health department and the community using local material.Aim To document the RSS project and to determine usefulness and costaffordability of these systems for cerebral palsy children and their families.
    Methods The details of RSS manufactured were retrieved from the clinic notes and secretary file. Parents of children who received the seating systems between July 2004 and September 2008 were invited to complete a 5-point Global Parental Perception Questionnaire (GPPQ) between December 2008 and January 2009.
    Results 277 RSS were manufactured between July 2004 and February 2011 (which included modified wheel chair, wooden chair, corner chair, buggy chair and standing frame), and used by children all over Sarawak. Parents of 73 children who used the seating systems completed the 5-points GPPQ. Ten families required full sponsorship. Children spent more time sitting up and brought outdoor more often after the systems became available. Majority of parents reported positive experience in their children with sitting ability, smiles, interaction with people, learning skills and easiness of doing physiotherapy. No change was noted with passing of motion drooling / oral secretion. Most parents agreed that the cost was affordable and worth paying.
    Conclusions A community based initiative to manufacture RSS by using locally available material and skill, at affordable price for the parents was feasible and useful for the family/children with CP.
  15. Ringga A, Ngian HU, Chin ZH, Toh TH
    Int J Public Health Res, 2011;1(2):1-3.
    MyJurnal
    Belaga District, in the heart of Borneo, is probably the most remote district in Sarawak. Although Belaga town is now accessible by land (50% are timber camp unsealed road) from Bintulu, the journey takes 5 hours and transport cost is high. Accessibility to Belaga by river is also subject to weather conditions and the town often gets cut off during the dry season and also during the wet season. All these pose immense challenges to the delivery of health care services to the people of Belaga and greatly reduce their accessibility to even basic health services. Access to specialist services is even more challenging as it is only available in Sibu and Bintulu; and visiting clinics in Belaga are infrequent due to the shortage of specialists and difficult transport. (Copied from article).
  16. Nazirah Alias, Mohd Azahadi Omar, Shubash Shander Ganapathy, Mohamad Fuad Mohamad Anuar, Chandrika Jeevananthan, Fazila Haryati Ahmad, et al.
    Int J Public Health Res, 2019;9(2):1108-1116.
    MyJurnal
    Substantial advances on the life expectancy have been achieved in Malaysia over the past few decades. It is essential that elderly lead a healthier old age which leans towards successful aging. Thus, this study describes the major causes of premature mortality among the elderly population in Malaysia, 2014.
  17. Rashidah Ambak, Balkish Mahadir Naidu, Mohd Azahadi Omar, Nor Azian Mohd Zaki, Syafinaz Mohd Sallehuddin, Tahir Aris
    Int J Public Health Res, 2014;4(2):449-456.
    MyJurnal
    Introduction Food labeling regulation has been implemented to enable consumers, including those with chronic diseases to make healthy informed choices before purchasing pre-packaged foods. The purpose of this study is to determine the prevalence of obese adults in Malaysia who practice reading food labels. It explored types of labels read and understanding of the information.
    Methods Findings presented in this study were captured from the secondary analysis of National Health and Morbidity Survey’s (NHMS, 2006) food label study which focused only on obese adults (BMI > 30 kg/m2) aged 18 and above. This nation-wide cross sectional study was conducted from April to August 2006 using an interview-based questionnaire. Complex data analysis was done using Stata version 12.0.
    Results There were 4565 obese respondents with the mean age of 33 ± 9.7 (18-60 years old). About 54.7% completed high-school and 9.9% were higher degree
    holders. Prevalence of obese adults who claimed to read label was 80.5% (95%CI: 79.3, 81.6). Findings showed significant results in reading and understanding labels among all age group categories, Malay, Indian and other Bumiputras, all education categories and married respondents. Expiry date was the highest percentage being read (74.5%), followed by fat content (15.3%), vitamin (11.8%) and carbohydrate (10.9%).
    Conclusions The obese population in Malaysia claimed to read and understand the food label but did not focus on specific macronutrients related to their health
    condition. Findings can be used to implement effective education programmes targeting the relevant groups to instill an awareness to read, understand and use the label information as one of the means in combating obesity.
    Study name: National Health and Morbidity Survey (NHMS-2006)
  18. Lim Kuang Kuay, Hasimah Ismail, Nur Liana Ab Majid, Thamil Arasu Saminathan, Rosnah Ramly, Chan Ying Ying, et al.
    Int J Public Health Res, 2020;10(1):1166-1173.
    MyJurnal
    The Ministry of Health, Malaysia had introduced the community based action programme (KOSPEN) to improve the early detection of non-communicable diseases (NCDs) in the population. This study aims to identify factors associated with non-participation in screening activities and its barriers.
  19. Zahir Izuan Azhar, Shamsul Azhar Shah, Tan, Susan, M.K., Syed Sharizman Syed Abdul Rahim
    Int J Public Health Res, 2016;6(1):713-718.
    MyJurnal
    Introduction The risk factors associated with mental health among adolescents are usually
    described by researchers at an individual level. Neighbourhood factors and
    health have opened a new insight into the field of epidemiology. The aim of
    this study was to assess the reliability and validity of a newly developed
    Neighbourhood Factors on Mental Health Questionnaire among Malaysian
    adolescents.

    Methods A cross-sectional study was conducted in four secondary schools in Kuala
    Lumpur, Malaysia using a newly developed questionnaire which comprised
    of two main domains and seven items. Exploratory factor analysis and
    Cronbach‟s alpha were used to measure the instrument‟s construct validity
    and reliability.

    Results A total of 106 adolescents participated in this research. The majority of
    adolescents were 13 years old (40.6%), female (55.7%), Malays (68.9%),
    have parents who only studied until secondary school (66.0%) and lived in
    flats (32.1%). Bartlett‟s Test of Sphericity was significant (Chi-square =
    258.361, p
  20. Sharifa Ezat Wan Puteh, Norin Rahayu Samsuddin, Sharifah Noor Akmal Syed Hussain, Shamsul Azhar Shah, Syed Mohamed Aljunid
    Int J Public Health Res, 2011;1(1):13-22.
    MyJurnal
    Accepted 10 August 2011.
    Introduction Cervical cancer (CC) is the second most prevalent female cancer in Malaysia. Almost 70% of its’ causal factors are attributable to oncogenic human papillomavirus (HPV) types 16, 18 and other risk factors. HPV genotypes distributions are also noted to differ by geographical area.
    Methods This was cross sectional study conducted in 2007, to determine the influencing factors of HPV positivity and prevalence of HPV infections among patients with cervical cancer in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). Patients’ paraffin-embedded cervical tissues kept in the Pathology Department from 1999 to 2007 were randomly selected. A total of 81 medical records with complete information were chosen as samples and patients were contacted for consent. Tissue samples were further derived for PCR DNA for HPV genotyping. Analyses included descriptive statistics; bivariate χ2 test and correlation were used to determine relationship between factors and HPV positivity. Significance level of less than 0.05 was taken as statistically significant.
    Results Mean age of cancer diagnosis was at 52 ± 12.2 years. Women of Chinese ethnicity was the highest ethnicity to be HPV positive at 65.4% and squamous cell carcinoma was more commonly found (59.3%) compared with other types of cancers. The prevalence of HPV positivity was 92.6% with type 16 being the most common (74.1%), followed by type 33 (30.9%) and 18 (22.2%). Multiple HPV infections were a common finding at 54.3%. Factors thought to influence positivity i.e. age of intercourse, number of sexual partners, number of parity, smoking status of patients and their partners, oral contraceptive usage, presence of chronic illnesses and cancer stage were not significantly associated with HPV positivity. Increased CC severity level was not associated with increased number of HPV infections (Pearson correlation 0.58; p =0.607).
    Conclusions High HPV positivity at 92.6% was found among ICC patients. Factors thought to influence HPV positivity were not significant. The top three HPV genotypes were type 16 followed by type 33 and 18. However, local women HPV serotypes findings need to be replicated in a larger population sample.
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