Displaying publications 1 - 20 of 34 in total

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  1. Moissinac K, To BC, Gul YA, Liew NC
    Trop Doct, 2001 Oct;31(4):217.
    PMID: 11676058
  2. Shriwas SR, Reddy TN
    Trop Doct, 1993 Oct;23(4):168-9.
    PMID: 8273161
  3. Shriwas SR
    Trop Doct, 1993 Jul;23(3):140.
    PMID: 8356755
  4. Doi SA, Tan CT, Liam CK, Naganathan K
    Trop Doct, 1998 Jan;28(1):34-9.
    PMID: 9481195
    We review our experience with 27 cases of pulmonary and meningeal cryptococcosis at the University Hospital, (Kuala Lumpar, Malaysia) where this is the most common cause of adult meningitis in patients without debilitating illnesses. Of the 27 cases analysed, six presented primarily with pulmonary symptomatology which usually were mainly cough, chest pain and low grade fever. The rest presented with primarily central nervous system (CNS) symptomatology of which headaches and fever were the most consistent symptoms although a third of these patients also had pulmonary lesions noted on chest radiographs. Treatment in all cases was with amphotericin B and 5-fluorocytosine and usually till a total cumulative dose of 1.5 g of amphotericin had been reached (an average of 10 weeks). Primary pulmonary presentations, if symptomatic, were treated as per CNS cryptococcosis due to the high likelihood of CNS dissemination. Incidental pulmonary cryptococcoma found on routine chest radiographs were confirmed by biopsy under ultrasound or fluoroscopy guidance and booked for surgical resection. Death usually occurred early in patients who presented late. Once patients responded to therapy, mortality was usually avoided. The only cause of morbidity in survivors was visual impairment or blindness, and this was attributed mainly to intracranial hypertension with residual deficits determined by the measures taken to lower intracranial pressures. Our experience suggests that: (i) symptomatic patients should have combination therapy with 5-fluorocytosine and amphotericin B till at least a cumulative dose of 1.5 g amphotericin B is reached irrespective of whether they have primary CNS or pulmonary symptomatology; (ii) non-symptomatic pulmonary cryptococcoma could be treated primarily by surgical resection; (iii) visual failure or papilloedema should be treated aggressively; and (iv) prognosis is good with adequate therapy and early presentation.
  5. Matlani M, Chakravarti A, Rawal A, Kashyap B, Gurtoo A
    Trop Doct, 2009 Apr;39(2):115-6.
    PMID: 19299303 DOI: 10.1258/td.2008.080257
    As well as dengue fever (DF) and dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS), other atypical manifestations of dengue virus infection have also been reported. The frequency of CNS involvement in dengue remains unknown, although isolated cases with neurological manifestations have been reported in Southeast Asia, Malaysia, Burma, Puerto Rico and India. We present two cases of encephalitis associated with DF and DHF from New Delhi, India.
  6. Wen LY, Mohamad NF, Ramli NM
    Trop Doct, 2023 Jan;53(1):97-99.
    PMID: 36380613 DOI: 10.1177/00494755221137628
    We report a clinical case of orbital lymphoma masquerading as orbital cellulitis. Orbital lymphoma and lymphoma of the orbital adnexa are relatively rare types of lymphoma. They represent the malignant end of a spectrum of lymphoproliferative lesions that occur in the orbit, conjunctiva and eyelid. Diffuse large B-cell lymphomas (DLBCL) with variable clinical presentations have a relatively poor prognosis with rapid visual loss. Therefore, thorough evaluation and assessment with a multi-specialty effort are warranted for earlier diagnosis and initiation of treatment to save life and prevent sight loss.
  7. Riaz R M, Kotian CM, Devaramane V, Umakanth S
    Trop Doct, 2023 Jan;53(1):164-166.
    PMID: 35876405 DOI: 10.1177/00494755221105632
    We report the case of a 23-year-old man without any significant premorbid conditions initially presenting to a psychiatrist with suspected depression but later referred to our hospital owing to the possibility of systemic disease and subsequently diagnosed as having disseminated tuberculosis.
  8. Razali SM
    Trop Doct, 2008 Apr;38(2):109-10.
    PMID: 18453507 DOI: 10.1258/td.2007.070001
    The prevalence of HIV/AIDS among drug addicts in Malaysia is high, especially among intravenous drug users. The present treatment and rehabilitation of drug addiction is considered as a failure. The government finally decided to start on Drug Substitution Therapy in early 2005 as an effort to prevent the spread of HIV/AIDS in the country.
  9. Arumainathan U, Kumar M, Raman R
    Trop Doct, 2003 Jan;33(1):31.
    PMID: 12568517
  10. Taba AH
    Trop Doct, 1980 Jan;10(1):21-3.
    PMID: 7368301
  11. Chen PC
    Trop Doct, 1971 Oct;1(4):183-6.
    PMID: 5152672
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