Displaying publications 1 - 20 of 55 in total

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  1. Che Mohamed SK, Abd Aziz A
    Malays J Med Sci, 2009 Oct;16(4):69-72.
    PMID: 22135515 MyJurnal
    When performing a radiological assessment for a trauma case with associated head injury, a fragment of dense tissue detected near the craniovertebral junction would rapidly be assessed as a fractured bone fragment. However, if further imaging and evaluation of the cervical spine with computerised tomography (CT) did not demonstrate an obvious fracture, then the possibility of ligament calcification would be considered. We present a case involving a previously healthy 44-yearold man who was admitted following a severe head injury from a road traffic accident. CT scans of the head showed multiple intracranial haemorrhages, while scans of the cervical spine revealed a small, well-defined, ovoid calcification in the right alar ligament. This was initially thought to be a fracture fragment. Although such calcification is uncommon, accident and emergency physicians and radiologists may find this useful as a differential diagnosis in patients presenting with neck pain or traumatic head injury.
    Matched MeSH terms: Calcinosis
  2. Cheen Hoe AK, Hamzah F, Abdul Khader MA
    Malays J Med Sci, 2014 Sep-Oct;21(5):75-7.
    PMID: 25977638 MyJurnal
    The detection rate of thyroid incidentalomas is increasing; in fact, as many as 2.3% of patients undergoing FDG PET-CT for other indications have been found to have thyroid incidentalomas. The risk of malignancy in these thyroid incidentalomas can be as high as 47%. The increased uptake and the focal uptake pattern of F-18 fluorodeoxyglucose (FDG) in the thyroid during positron emission tomography (PET)-computed tomography (CT), and the calcification of the thyroid incidentaloma, are associated with even higher risk of malignancy. We report a case of a lady undergoing FDG PET-CT for breast cancer staging but noted to have a calcified thyroid incidentaloma, which was proven to be follicular thyroid carcinoma.
    Matched MeSH terms: Calcinosis
  3. Ong, Wu Zhuan, Jamalia Rahmat, Ramasamy, Sunder, Amir Samsudin
    MyJurnal
    Retinoblastoma is a rare intraocular malignant tumour more commonly seen in children below five years of age. We presented a rare case of retinoblastoma in an older child. A nine-year-old girl noticed that she had loss of vision OS following a fall at home. Her vision was 6/6 OD and only light perception OS. Examination of the left eye revealed an extensive exudative retinal detachment. Her right eye examination was unremarkable. CT scan showed a left eye intraocular mass with calcification. EUA revealed a mixed endophytic and exophytic mass with extensive exudative retinal detachment. Family members consented to left eye enucleation and histopathological report confirmed the diagnosis of retinoblastoma. Post enucleation, patient is doing well with a prosthetic eye. In conclusion, any unexplained visual loss in children regardless of age warrants a full ophthalmological examination as the possibility of retinoblastoma cannot be ruled out.
    Matched MeSH terms: Calcinosis
  4. Arumugasamy N
    Med J Malaya, 1966 Dec;21(2):140-8.
    PMID: 4227385
    Matched MeSH terms: Calcinosis/radiography*
  5. Arumugasamy N
    Med J Malaya, 1966 Dec;21(2):149-60.
    PMID: 4227386
    Matched MeSH terms: Calcinosis/pathology*
  6. Whittaker DK, Bakri MM
    Arch Oral Biol, 1996 Jan;41(1):15-9.
    PMID: 8833585
    One hundred and ninety-eight single-rooted teeth from individuals aged 21-90 yr of Caucasian, Malay, Chinese Malay and Indian Malay origin were studied. Single or serial longitudinal sections of extracted teeth were cut following dye imbibition of patent dentinal tubules. The extent of sclerosis of apical dentinal tubules was assessed and correlated with the age of the individual. Correlation with age was higher in the Caucasian than the Malay races and within the Malaysian racial groups correlation with age was highest in the Malays and lowest in the Chinese. It is concluded that factors other than age may be important in the formation of sclerotic apical dentine in teeth of different racial origin. The effect of racial origin should be considered when using sclerosis as a means of age determination in forensic cases.
    Matched MeSH terms: Calcinosis/pathology
  7. Kobayashi K, Asakura T, Kawada I, Hasegawa H, Chubachi S, Ohara K, et al.
    Medicine (Baltimore), 2019 Apr;98(17):e15264.
    PMID: 31027078 DOI: 10.1097/MD.0000000000015264
    RATIONALE: Histoplasmosis occurs most commonly in Northern and Central America and Southeast Asia. Increased international travel in Japan has led to a few annual reports of imported histoplasmosis. Healed sites of histoplasmosis lung infection may remain as nodules and are often accompanied by calcification. Previous studies in endemic areas supported the hypothesis that new infection/reinfection, rather than reactivation, is the main etiology of symptomatic histoplasmosis. No previous reports have presented clinical evidence of reactivation.

    PATIENT CONCERNS: An 83-year-old Japanese man was hospitalized with general fatigue and high fever. He had been treated with prednisolone at 13 mg/d for 7 years because of an eczematous skin disease. He had a history of travel to Los Angeles, Egypt, and Malaysia 10 to 15 years prior to admission. Five years earlier, computed tomography (CT) identified a solitary calcified nodule in the left lingual lung segment. The nodule size remained unchanged throughout a 5-year observation period. Upon admission, his respiratory condition remained stable while breathing room air. CT revealed small, randomly distributed nodular shadows in the bilateral lungs, in addition to the solitary nodule.

    DIAGNOSIS: Disseminated histoplasmosis, based on fungal staining and cultures of autopsy specimens.

    INTERVENTIONS: The patient's fever continued despite several days of treatment with meropenem, minocycline, and micafungin. Although he refused bone marrow aspiration, isoniazid, rifampicin, ethambutol, and prednisolone were administered for a tentative diagnosis of miliary tuberculosis.

    OUTCOMES: His fever persisted, and a laboratory examination indicated severe thrombocytopenia with disseminated intravascular coagulation. He died on day 43 postadmission. During autopsy, the fungal burden was noted to be higher in the calcified nodule than in the disseminated nodules of the lung, suggesting a pathogenesis involving endogenous reactivation of the nodule and subsequent hematogenous and lymphatic spread.

    LESSONS: Physicians should consider histoplasmosis in patients with calcified nodules because the infection may reactivate during long-term corticosteroid therapy.

    Matched MeSH terms: Calcinosis
  8. Ng KH, Looi LM, Bradley DA
    Br J Radiol, 1996 Apr;69(820):326-34.
    PMID: 8665132
    X-ray microradiography of surgically excised breast specimens offers the possibility of morphological characterization of calcifications. When combined with digital imaging techniques there exists added potential for obtaining valuable basic quantitative morphometric information regarding differences between microcalcifications in tissues exhibiting evidence of fibrocystic change, benign and malignant tumours. A total of 157 excised breast specimens from 84 patients were microradiographed using a Softex Super Soft X-ray unit and Kodak AA high resolution industrial film. A Quantimet 570C image analysis system was used to digitize and analyse the microradiographs. Of the 157 microradiographs, 51 (from 30 patients) revealed microcalcification clusters. The existence of significant differences between the three identified categories of tissue were indicated by clustering parameters. These included the number of particles per cluster, area of clusters, maximum distance to nearest neighbour, and geometric mean distance to nearest neighbour. The distribution pattern index (DPI), another of the clustering parameters used in this study, has been observed to be a particularly powerful discriminator. The value for fibrocystic change was found to be significantly smaller (0.514) than that for benign tumour (0.796) whilst that for benign tumour was observed to be significantly larger than that for malignant tumour (0.604) at a p-value of less than 0.05 (Kruskal-Wallis one-way analysis of variance).
    Matched MeSH terms: Calcinosis/etiology; Calcinosis/radiography*
  9. Kwan MK, Abdelhai AM, Saw LB, Chan CY
    Spine (Phila Pa 1976), 2012 Dec 15;37(26):E1676-9.
    PMID: 23044619 DOI: 10.1097/BRS.0b013e318276b48c
    Case report.
    Matched MeSH terms: Calcinosis/drug therapy*; Calcinosis/pathology; Calcinosis/radiography
  10. Lim CH, Lin CT, Chen YH
    Int J Rheum Dis, 2017 Dec;20(12):2249-2252.
    PMID: 28036155 DOI: 10.1111/1756-185X.12969
    Matched MeSH terms: Calcinosis/diagnosis; Calcinosis/etiology*; Calcinosis/therapy; Chondrocalcinosis/complications*; Chondrocalcinosis/diagnosis; Chondrocalcinosis/therapy
  11. Chai WL, Phang YH, Chong HC
    MyJurnal
    Tumoral calcinosis is an uncommon condition which has been described to exist in primary and secondary forms. A lack of awareness of this entity can lead to unnecessary procedures and incorrect management. We report a case of a patient on peritoneal dialysis who presented with multiple painful joint swellings to the orthopaedic department. An initial diagnosis of septic arthritis was made, then revised to chronic tophaceous gout and referred to the rheumatology unit.
    Matched MeSH terms: Calcinosis; Calcinosis/pathology
  12. Zain RB, Fei YJ
    Oral Surg. Oral Med. Oral Pathol., 1990 Oct;70(4):466-70.
    PMID: 2120653
    Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, 79.5% were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7%) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.
    Matched MeSH terms: Calcinosis/pathology
  13. Zain RB, Fei YJ
    Odontostomatol Trop, 1990 Sep;13(3):94-6.
    PMID: 2075149
    Peripheral fibroma/fibrous epulis accounts for the great majority of localised gingival swellings as was substantiated by various reports in the literature. A study was undertaken to investigate the clinical features of a series of 204 localised fibrous gingival swellings received by the Histopathology Laboratory, Department of Oral Surgery, National University of Singapore. The female patients were more affected than the male patients and the lesions occurred predominantly among the Chinese. The lesions were mainly pedunculated and most commonly occurred in anterior maxilla. The recurrence rate was about 10.3%. In conclusion the results obtained in this study were overall in agreement with those of other authors.
    Matched MeSH terms: Calcinosis
  14. Arasaratnam S, Abdullah BJJ, Fernandez V
    Med J Malaysia, 1998 Sep;53(3):290-2.
    PMID: 10968170
    We present a case of rare pitfall in the diagnosis of an oesophageal foreign body due to the calcified vertical plate of the cricoid to highlight the need to be aware of this entity to avoid unnecessary morbidity.
    Matched MeSH terms: Calcinosis/diagnosis*; Calcinosis/pathology; Calcinosis/radiography; Calcinosis/surgery
  15. Narverud SF, Ramli NB, Chandran H, Ganesan D
    Eur Spine J, 2013 May;22 Suppl 3:S443-9.
    PMID: 23233216 DOI: 10.1007/s00586-012-2610-7
    In this article, we review the English literature of calcified pseudomeningoceles in the lumbar region.
    Matched MeSH terms: Calcinosis/pathology*
  16. Burns-Cox CJ, Prathap K, Clark E, Gillman R
    Trans R Soc Trop Med Hyg, 1969;63(3):409-11.
    PMID: 5815876
    Matched MeSH terms: Calcinosis
  17. Harrower G
    Matched MeSH terms: Calcinosis
  18. Zaimi MA, Mamat AZ, Ghazali MZ, Zakaria AD, Sahid NA, Hayati F
    Oxf Med Case Reports, 2020 Oct;2020(10):omaa083.
    PMID: 33133617 DOI: 10.1093/omcr/omaa083
    Constrictive pericarditis is a disabling disease of the heart, which causes cardiac diastolic dysfunction. We present a case of a 44-year-old gentleman with a history of blunt chest trauma who presented with constrictive pericarditis with right-sided heart failure. Imaging studies revealed a calcified pericardium. He underwent an uneventful pericardiectomy. Calcification is common yet rare if it involves the pericardium. It normally occurs following fibrosis and adhesion which are associated with the chronicity of the disease, hence creating more challenge to the operating surgeon in the pericardiectomy procedure.
    Matched MeSH terms: Calcinosis
  19. Imisairi AH, Hisham AN
    ANZ J Surg, 2009 Jun;79(6):488-9.
    PMID: 19566876 DOI: 10.1111/j.1445-2197.2009.04953.x
    Matched MeSH terms: Calcinosis/radiography*
  20. Ch'ng LS, Bux SI, Liam CK, Rahman NA, Ho CY
    Korean J Radiol, 2013 Sep-Oct;14(5):859-62.
    PMID: 24043987 DOI: 10.3348/kjr.2013.14.5.859
    Pulmonary alveolar microlithiasis (PAM) is a rare chronic disease with paucity of symptoms in contrast to the imaging findings. We present a case of a 24-year-old Malay man having an incidental abnormal pre-employment chest radiograph of dense micronodular opacities giving the classical "sandstorm" appearance. High-resolution computed tomography of the lungs showed microcalcifications with subpleural cystic changes. Open lung biopsy showed calcospherites within the alveolar spaces. The radiological and histopathological findings were characteristic of PAM.
    Matched MeSH terms: Calcinosis/diagnosis*; Calcinosis/surgery
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