MyMedR

Calcinosis of hand and axilla in polymyositis/dermatomyositis

Zulkifli A

Med J Malaysia, 1979 Jun;33(4):362-4.

PMID: 522752

Matched MeSH terms: Calcinosis/drug therapy; Calcinosis/etiology*

Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases

Zain RB, Fei YJ

Oral Surg. Oral Med. Oral Pathol., 1990 Oct;70(4):466-70.

PMID: 2120653

Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, 79.5% were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7%) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.

Matched MeSH terms: Calcinosis/pathology

Peripheral fibroma/fibrous epulis with and without calcifications. A clinical evaluation of 204 cases in Singapore

Zain RB, Fei YJ

Odontostomatol Trop, 1990 Sep;13(3):94-6.

PMID: 2075149

Peripheral fibroma/fibrous epulis accounts for the great majority of localised gingival swellings as was substantiated by various reports in the literature. A study was undertaken to investigate the clinical features of a series of 204 localised fibrous gingival swellings received by the Histopathology Laboratory, Department of Oral Surgery, National University of Singapore. The female patients were more affected than the male patients and the lesions occurred predominantly among the Chinese. The lesions were mainly pedunculated and most commonly occurred in anterior maxilla. The recurrence rate was about 10.3%. In conclusion the results obtained in this study were overall in agreement with those of other authors.

Matched MeSH terms: Calcinosis

Fulltext Trapped heart in heavily calcified pericardium

Zaimi MA, Mamat AZ, Ghazali MZ, Zakaria AD, Sahid NA, Hayati F

Oxf Med Case Reports, 2020 Oct;2020(10):omaa083.

PMID: 33133617 DOI: 10.1093/omcr/omaa083

Constrictive pericarditis is a disabling disease of the heart, which causes cardiac diastolic dysfunction. We present a case of a 44-year-old gentleman with a history of blunt chest trauma who presented with constrictive pericarditis with right-sided heart failure. Imaging studies revealed a calcified pericardium. He underwent an uneventful pericardiectomy. Calcification is common yet rare if it involves the pericardium. It normally occurs following fibrosis and adhesion which are associated with the chronicity of the disease, hence creating more challenge to the operating surgeon in the pericardiectomy procedure.

Matched MeSH terms: Calcinosis

A TAXONOMIC STUDY OF THE GENUS PADINA (DICTYOTALES, PHAEOPHYCEAE) INCLUDING THE DESCRIPTIONS OF FOUR NEW SPECIES FROM JAPAN, HAWAII, AND THE ANDAMAN SEA(1)

Win NN, Hanyuda T, Arai S, Uchimura M, Prathep A, Draisma SG, et al.

J Phycol, 2011 Oct;47(5):1193-209.

PMID: 27028247 DOI: 10.1111/j.1529-8817.2011.01054.x

A taxonomic study of the genus Padina from Japan, Southeast Asia, and Hawaii based on morphology and gene sequence data (rbcL and cox3) resulted in the recognition of four new species, that is, Padina macrophylla and Padina ishigakiensis from Ryukyu Islands, Japan; Padina maroensis from Hawaii; and Padina usoehtunii from Myanmar and Thailand. All species are bistratose and morphologically different from one another as well as from any known taxa by a combination of characters relating to degree of calcification; the structure, position, and arrangement of hairlines (HLs) and reproductive sori; and the presence or absence of rhizoid-like groups of hairs and an indusium. Molecular phylogenetic analyses demonstrated a close relationship between P. ishigakiensis, P. macrophylla, P. maroensis, and Padina australis Hauck. The position of P. usoehtunii, however, was not fully resolved, being either sister to a clade comprising the other three new species and P. australis in the rbcL tree or more closely related to a clade comprising several other recently described species in the cox3 tree. The finding of the four new species demonstrates high species diversity particularly in southern Japan. The following characters were first recognized here to be useful for species delimitation: the presence or absence of small rhizoid-like groups of hairs on the thallus surface, structure and arrangement of HLs on both surfaces either alternate or irregular, and arrangement of the alternating HLs between both surfaces in equal or unequal distance. The evolutionary trajectory of these and six other morphological characters used in species delineation was traced on the phylogenetic tree.

Matched MeSH terms: Calcinosis

Racial variations in the extent of tooth root translucency in ageing individuals

Whittaker DK, Bakri MM

Arch Oral Biol, 1996 Jan;41(1):15-9.

PMID: 8833585

One hundred and ninety-eight single-rooted teeth from individuals aged 21-90 yr of Caucasian, Malay, Chinese Malay and Indian Malay origin were studied. Single or serial longitudinal sections of extracted teeth were cut following dye imbibition of patent dentinal tubules. The extent of sclerosis of apical dentinal tubules was assessed and correlated with the age of the individual. Correlation with age was higher in the Caucasian than the Malay races and within the Malaysian racial groups correlation with age was highest in the Malays and lowest in the Chinese. It is concluded that factors other than age may be important in the formation of sclerotic apical dentine in teeth of different racial origin. The effect of racial origin should be considered when using sclerosis as a means of age determination in forensic cases.

Matched MeSH terms: Calcinosis/pathology

Calcareous deposits in the subdeltoid bursa

Tan KC

Journal of the Malaya Branch of the British Medical Association, 1941;5:60-1.

Matched MeSH terms: Calcinosis

Fulltext Tropical calcific pancreatitis

Tan CT, Kannan P, Sng KH

Med J Malaysia, 1980 Dec;35(2):150-4.

PMID: 7266409

Matched MeSH terms: Calcinosis/diagnosis*

Calcifying fibroblastic granuloma. A case report

Taiyeb Ali TB, Siar CH

J N Z Soc Periodontol, 1997.

PMID: 9522721

Matched MeSH terms: Calcinosis/pathology*

Fulltext 3D-Printed Coronary Plaques to Simulate High Calcification in the Coronary Arteries for Investigation of Blooming Artifacts

Sun Z, Ng CKC, Wong YH, Yeong CH

Biomolecules, 2021 09 03;11(9).

PMID: 34572520 DOI: 10.3390/biom11091307

The diagnostic value of coronary computed tomography angiography (CCTA) is significantly affected by high calcification in the coronary arteries owing to blooming artifacts limiting its accuracy in assessing the calcified plaques. This study aimed to simulate highly calcified plaques in 3D-printed coronary models. A combination of silicone + 32.8% calcium carbonate was found to produce 800 HU, representing extensive calcification. Six patient-specific coronary artery models were printed using the photosensitive polyurethane resin and a total of 22 calcified plaques with diameters ranging from 1 to 4 mm were inserted into different segments of these 3D-printed coronary models. The coronary models were scanned on a 192-slice CT scanner with 70 kV, pitch of 1.4, and slice thickness of 1 mm. Plaque attenuation was measured between 1100 and 1400 HU. Both maximum-intensity projection (MIP) and volume rendering (VR) images (wide and narrow window widths) were generated for measuring the diameters of these calcified plaques. An overestimation of plaque diameters was noticed on both MIP and VR images, with measurements on the MIP images close to those of the actual plaque sizes (<10% deviation), and a large measurement discrepancy observed on the VR images (up to 50% overestimation). This study proves the feasibility of simulating extensive calcification in coronary arteries using a 3D printing technique to develop calcified plaques and generate 3D-printed coronary models.

Matched MeSH terms: Calcinosis/pathology*

The combined epithelial odontogenic tumour in Malaysians

Siar CH, Ng KH

Br J Oral Maxillofac Surg, 1991 Apr;29(2):106-9.

PMID: 2049349

The combined epithelial odontogenic tumour represents a hybrid lesion comprising primarily areas of adenomatoid odontogenic tumour intermixed with foci of calcifying epithelial odontogenic tumour. Five such cases retrieved from the files of the Division of Stomatology, Institute for Medical Research, Kuala Lumpur, and four others from the existing literature were analysed. A mean age of 18.8 years, a female preponderance (66.7%) with a male to female ratio of 1:2 and predilection for the mandible (55.6%) were observed. All cases were treated by conservative surgery and the lack of recurrence confirmed the innocuous nature of this lesion.

Matched MeSH terms: Calcinosis/pathology

Calcifying and keratinizing ameloblastoma of the maxilla

Siar CH, Ng KH

J Laryngol Otol, 1991 Nov;105(11):971-2.

PMID: 1722237

A case is described of ameloblastoma of maxilla presenting with numerous calcified keratin pearls. The significance of cellular variation in relation to the behavioural potential of the ameloblastoma in general is briefly discussed.

Matched MeSH terms: Calcinosis/pathology

Fulltext The role of computed tomography in the evaluation of retinoblastoma

Sherazi ZA, Jayakumar CR

Singapore Med J, 1992 Oct;33(5):496-9.

PMID: 1455277

To assess the importance of Computed Tomography(CT) in the evaluation of retinoblastoma, we reviewed thirteen cases of retinoblastoma which presented at Hospital University Sains Malaysia, Kelantan, Malaysia, from August 1986 to June 1991. High resolution computed tomography of the orbits was performed in all patients prior to therapy. Nine patients (69%) had unilateral and four (31%) had bilateral retinoblastoma. The interesting features were the remarkably high incidence in the right eye (89%) as compared to the left eye (11%) in unilateral retinoblastoma, and overall predominance of the male population (male to female ratio was 2:1). Computed tomography detected intraocular calcification in 82% of the tumourous eyes. All patients presented at late stages when tumours were of large size. The presence of calcification was not related to the size of the tumour. CT detected calcification in a suspected retinoblastoma with a high degree of accuracy. Computed tomographic evidence of intraocular calcification in children under 3 years of age is highly suggestive of retinoblastoma.

Matched MeSH terms: Calcinosis/radiography

Paracetamol: a cause for analgesic nephropathy and end-stage renal disease

Segasothy M, Suleiman AB, Puvaneswary M, Rohana A

Nephron, 1988;50(1):50-4.

PMID: 3050572

180 patients with end-stage renal disease (ESRD) on maintenance dialysis and those who had undergone renal transplantation were questioned retrospectively. 14 patients had consumed excessive quantities of analgesics (greater than 1 kg) prior to the institution of long-term dialysis or transplantation. Sonographic examination done on these patients indicated that 7 had renal papillary necrosis (RPN). The sonographic features were renal papillary calcifications surrounding the central sinus in a complete or incomplete garland pattern. In 5 of these patients RPN is attibutable to the excessive consumption of paracetamol. We have earlier reported 10 cases of RPN due to excessive consumption of paracetamol. Thus 15 cases of RPN attributable to paracetamol consumption (1.0-15.3 kg over a period ranging from 3 to 23 years) have been documented. It is concluded that paracetamol may assume an increasingly important role in the causation of analgesic nephropathy (AN) and ESRD.

Matched MeSH terms: Calcinosis/chemically induced; Calcinosis/diagnosis

Calcific pancreatitis: the Indian plague

Rupa B, Rao GV, Nageshwar R

Med J Malaysia, 2005 Jul;60 Suppl B:99-100.

PMID: 16108186

Matched MeSH terms: Calcinosis/classification; Calcinosis/diagnosis*; Calcinosis/physiopathology

Brain calcification in patients with cerebral lupus

Raymond AA, Zariah AA, Samad SA, Chin CN, Kong NC

Lupus, 1996 Apr;5(2):123-8.

PMID: 8743125 DOI: 10.1177/096120339600500207

Cerebral lupus (CL) is a common cause of morbidity and mortality in patients with SLE. The brain CTs of 27 consecutive adult patients with SLE and various neurological presentations were reviewed. The median age and duration of neurological symptoms at the time of the brain CT were 30 years (range = 14-51 years) and six days (range = 1 day-22 years), respectively. Eleven patients (41%) had normal CTs. The abnormalities in the remaining patients could be divided into six categories: (a) cerebral atrophy alone (two patients); (b) calcification alone (three patients); (c) infarct(s) alone (five patients); (d) cerebral atrophy and calcification (three patients); (e) cerebral atrophy and infarct(s) (one patient) and (f) cerebral atrophy, calcification and infarct(s) (two patients). Altogether eight patients (30%) (age range = 17-47 years) had intracerebral calcification: the globus pallidus was involved in all, putamen in two, head of the caudate nucleus in one, thalamus in one, centrum semiovale in two and cerebellum in three patients. Two patients had extensive calcifications of most of the basal ganglia, centrum semiovale and cerebellum. There was no relationship between the presence/degree of calcification and age of patients/duration or type of neurological presentation. The pathogenesis of cerebral calcification in CL is unknown. Cerebral lupus must now be included in the differential diagnosis of intracerebral calcification.

Matched MeSH terms: Calcinosis/pathology*

Large-cell calcifying Sertoli cell tumour with macrocalcification in partially resected testis of young adult patient

Potić Floranović M, Ristić Petrović A, Stojnev S, Potić M, Petrović F, Janković Veličkovic L

Malays J Pathol, 2018 Dec;40(3):343-348.

PMID: 30580367

INTRODUCTION: There are less than 100 cases of Large-cell calcifying Sertoli cell tumour (LCCSCT) reported in English literature. Most of them are benign, bilateral and affect paediatric population. Malignant cases occur in older patients. LCCSCT is often associated with Carney complex or Peutz-Jaghers syndrome. We present the clinicopathological features of a young adult, with unilateral "stone-like" LCCSCT, without changes in hormonal status and no clinical characteristics of noted genetic disorders.

CASE REPORT: A 24-year-old male presented with painless hardening of the right testis. There was no gynaecomastia, and serum levels of human chorionic gonadotropin and α-fetoprotein were normal. Ultrasound depicted hyperechogenic, clearly demarcated intratesticular lesion. Partial orchiectomy was performed. Macroscopically, tumour appeared as almost entirely calcified round mass, measuring 10 mm. Histopathological evaluation showed well-circumscribed, unencapsulated tumour composed of massive calcified geographic formations, surrounded with tumour cells. Neoplastic cells were large, polygonal, with abundant eosinophilic cytoplasm, and formed irregular cords, pseudo tubular structures, and nests in a fibrous and myxoid stroma, surrounded with lymphocytes. Other forms of calcification were also present: Needle-like deposits and lamellar, mulberry-like structures. There was no necrosis, mitotic activity and nuclear pleomorphism. Immunohistochemical study was positive for inhibin α and negative for Melan A, EMA, synaptophysin, chromogranin and AFP.

DISCUSSION: LCCSCT needs to be differentiated from other, more frequent, sex cord stromal tumours. Clinical and genetical evaluation of these patients had to be performed, due to connection of LCCSCT with genetic abnormalities. In evidently benign cases, organ-sparing surgery should be considered for younger patients, followed by long term follow-up.

Matched MeSH terms: Calcinosis/pathology*; Calcinosis/surgery

The incidence of pineal calcification in the adult Singapore population

Oon CL

Med J Malaysia, 1975 Dec;30(2):149-52.

PMID: 1228381

Matched MeSH terms: Calcinosis/epidemiology*

Fulltext Retinoblastoma in an older child: a case report

Ong, Wu Zhuan, Jamalia Rahmat, Ramasamy, Sunder, Amir Samsudin

Malaysian Journal of Medicine and Health Sciences, 2018;14(2):93-96.

MyJurnal

Retinoblastoma is a rare intraocular malignant tumour more commonly seen in children below five years of age. We presented a rare case of retinoblastoma in an older child. A nine-year-old girl noticed that she had loss of vision OS following a fall at home. Her vision was 6/6 OD and only light perception OS. Examination of the left eye revealed an extensive exudative retinal detachment. Her right eye examination was unremarkable. CT scan showed a left eye intraocular mass with calcification. EUA revealed a mixed endophytic and exophytic mass with extensive exudative retinal detachment. Family members consented to left eye enucleation and histopathological report confirmed the diagnosis of retinoblastoma. Post enucleation, patient is doing well with a prosthetic eye. In conclusion, any unexplained visual loss in children regardless of age warrants a full ophthalmological examination as the possibility of retinoblastoma cannot be ruled out.

Matched MeSH terms: Calcinosis

Accuracy of 64-row multidetector computed tomography in detecting coronary artery disease in 134 symptomatic patients: influence of calcification

Ong TK, Chin SP, Liew CK, Chan WL, Seyfarth MT, Liew HB, et al.

Am Heart J, 2006 Jun;151(6):1323.e1-6.

PMID: 16781246

The new 64-row multidetector computed tomography (CT)-assisted angiography can now detect coronary artery disease with shorter breath-hold time and at faster heart rates for symptomatic patients. We aim to determine if the 64-row scanner can also overcome limitations due to mild to moderate calcification.

Matched MeSH terms: Calcinosis/complications; Calcinosis/radiography*

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