MyMedR

Displaying publications 1 - 20 of 151 in total

Abstract:

Sort:

Fulltext Prosocial motives underlie scientific censorship by scientists: A perspective and research agenda

Clark CJ, Jussim L, Frey K, Stevens ST, Al-Gharbi M, Aquino K, et al.

Proc Natl Acad Sci U S A, 2023 Nov 28;120(48):e2301642120.
PMID: 37983511 DOI: 10.1073/pnas.2301642120

Science is among humanity's greatest achievements, yet scientific censorship is rarely studied empirically. We explore the social, psychological, and institutional causes and consequences of scientific censorship (defined as actions aimed at obstructing particular scientific ideas from reaching an audience for reasons other than low scientific quality). Popular narratives suggest that scientific censorship is driven by authoritarian officials with dark motives, such as dogmatism and intolerance. Our analysis suggests that scientific censorship is often driven by scientists, who are primarily motivated by self-protection, benevolence toward peer scholars, and prosocial concerns for the well-being of human social groups. This perspective helps explain both recent findings on scientific censorship and recent changes to scientific institutions, such as the use of harm-based criteria to evaluate research. We discuss unknowns surrounding the consequences of censorship and provide recommendations for improving transparency and accountability in scientific decision-making to enable the exploration of these unknowns. The benefits of censorship may sometimes outweigh costs. However, until costs and benefits are examined empirically, scholars on opposing sides of ongoing debates are left to quarrel based on competing values, assumptions, and intuitions.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Transformer incipient fault identification using depolarisation current ratio index analysis technique

Mohd Aizam Talib, Nor Asiah Muhamad, Zulkurnain Abdul Malek

Pertanika Journal of Science & Technology, 2017;25(102):267-274.
MyJurnal

Preventive tests and diagnosis of in-service power transformer are important for early fault prediction and increased reliability of electricity supply. However, some existing diagnostic techniques require transformer outage before the measurement can be performed and need expert knowledge and experiences to interpret the measurement results. Other measurement techniques such as chemical analyses of insulating oil may cause significant variance to measurement results due to different practices in oil sampling, storage, handling and transportation of oil. A cost-effective measuring technique, which is simple, providing fast and an accurate measurement results, is therefore highly required. The extended application of Polarisation and Depolarisation (PDC) measurement for characterisation of different faults conditions in-service power transformer has been presented in this paper. Earlier studies on polarisation and depolarisation current of oil samples from in-service power transformer shows that depolarisation has provided significant information about the change of material properties due to faults in power transformer. In this paper, a new approach based on Depolarisation Current Ratio Index (DRI) was developed for identifying and classifying different transformer fault conditions. The DRI at time interval of 4s to 100s was analysed and the results show that DRI of depolarisation current between 5/100s and 10/100s provides higher correlation on the incipient faults in power transformer.

Matched MeSH terms: Costs and Cost Analysis
Structural Change of Palm Oil Price Data

Lalang Buana, Ahmad Mahir Razali, Zainodin Haji Jubok

Sains Malaysiana, 1997;26.

The changes on the vegetables oil trading environment might change the foundation of palm oil pricing and induce a structural change to the price model. Failing to take it account the structural change in a data series might lead to misspecification of the actual model. This study, however, showed that structural change was not present in the monthly, January 1983 to July 1995, palm oil price, but it was present on the unconditional variance. The underlying model of this series was ARIMA (3, 1, 0) with ARCH (1). The critical change of the unconditional variance took place in April 1989.
Perubahan dalam suasana perdagangan minyak sayuran boleh mengubah asas harga minyak kelapa sawit. Seterusnya ia merangsang perubahan dalam struktur model harga minyak tersebut. Kegagalan untuk mengambil kira perubahan struktur dalam siri data menjadikan model itu tidak menepati spesifikasi daripada model sebenar. Kajian ini mendapati bahawa perubahan struktur tidak berlaku bagi data harga minyak sawit dari Januari 1983 hingga Julai 1995. Tetapi perubahan berlaku pada varians tidak bersyaratnya. Model asas bagi siri ini adalah ARIMA (3,1,0) dengan ARCH(1). Didapati juga bahawa perubahan yang kritikal bagi varians tidak bersyarat berlaku pada bulan April 1989.

Matched MeSH terms: Costs and Cost Analysis
Development of Low-Cost Microcontroller-Based Interface for Data Acquisition and Control of Microbioreactor Operation

Husain AR, Hadad Y, Zainal Alam MN

J Lab Autom, 2016 Oct;21(5):660-70.
PMID: 26185253 DOI: 10.1177/2211068215594770

This article presents the development of a low-cost microcontroller-based interface for a microbioreactor operation. An Arduino MEGA 2560 board with 54 digital input/outputs, including 15 pulse-width-modulation outputs, has been chosen to perform the acquisition and control of the microbioreactor. The microbioreactor (volume = 800 µL) was made of poly(dimethylsiloxane) and poly(methylmethacrylate) polymers. The reactor was built to be equipped with sensors and actuators for the control of reactor temperature and the mixing speed. The article discusses the circuit of the microcontroller-based platform, describes the signal conditioning steps, and evaluates the capacity of the proposed low-cost microcontroller-based interface in terms of control accuracy and system responses. It is demonstrated that the proposed microcontroller-based platform is able to operate parallel microbioreactor operation with satisfactory performances. Control accuracy at a deviation less than 5% of the set-point values and responses in the range of few seconds have been recorded.

Matched MeSH terms: Costs and Cost Analysis*
Winner's curse, size effect and bandwagon effect in explaining the under-pricing phenomenon of Malaysian IPOs

Yong, Othman

CREAM : Current Research in Malaysia (Penyelidikan Terkini di Malaysia), 2013;2(1):101-120.
MyJurnal

This study examines the issues of winner's curse, size effect and bandwagon effect in explaining the under-pricing phenomenon of Malaysian IPOs, for the period from January 2001 to December 2008. The average initial return for the Malaysian private placement IPOs (a proxy for informed investors) is significantly lower than that of the non-private placement IPOs (a proxy for uninformed investors), which gives support to the winner's curse hypothesis, where uninformed investors demand a higher initial return in the absence of informed investors. Using listing board as proxy for size of companies, we find that the smaller the company, the higher the average initial return, thus giving support to size effect, where investors usually demand higher initial return for smaller companies due to their higher perceived risk. The study also finds that the presence of a large number of informed investors as compared to uninformed investors in an IPO exercise will result in an increase in demand for that particular stock in the secondary market, which gives support to the bandwagon effect.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Budget impact analysis of biphasic insulin Aspart in the treatment of type 2 diabetes mellitus In Malaysia: a public payer perspective. [Abstract]

Tan SC, Matzen P, Yeo LN

Value Health, 2014 Nov;17(7):A743.
PMID: 27202679 DOI: 10.1016/j.jval.2014.08.151

Objectives
Budget impact analysis (BIA) is a useful tool for reimbursement decision-makers in health technology assessments by authorities across different countries. This study aimed to evaluate the financial impact from the Ministry of Health (MOH) perspective of different adoption rates of Biphasic Insulin Aspart (BIAsp) versus Biphasic Human Insulin (BHI) in treating type 2 diabetes mellitus.
Methods
An Excel basfed 5-year budget impact model was built to estimate insulin treated patients by public providers using local prevalence data. The published demographic, efficacy and adverse event data for ASEAN subgroup analyses of A1chieve study was applied. Both insulin acquisition costs and other medical costs for complications e.g. major hypoglycaemia, myocardial infarction, stroke, end-stage renal disease, blindness and amputation were included at a discount rate of 3%. The incidence rates of these complications were derived from the established UKPDS equations. The adoption rates were assumed and projected from the 2013 utilisation volume data of BIAsp and BHI by public providers. Sensitivity analyses were conducted.
Results
The adoption rates of BIAsp were assumed to increase from 1.8% in 2013 to 4.5% or 6.9% in 2018 for base case and upside scenario, respectively. Compared to the base case, upside scenario of wider BIAsp adoption was associated with an increased insulin cost up to RM 8.2M which was offset by avoided complication costs resulting in an overall net budget saving of approximately RM 5.5M over 5 years, primarily driven by estimated reduction in major hypoglycaemia events for patients treated with BIAsp.
Conclusions
The higher and wider adoption of BIAsp would likely be associated with cost savings in Malaysia from the MOH perspective attributed to its superiority in H1Ac reduction and lower major hypoglycemia risk in comparison to BHI. More cost saving would be concluded if productivity loss is included from a societal perspective.

Matched MeSH terms: Costs and Cost Analysis*
Molecular simulation on the stability and adsorption properties of choline-based ionic liquids/IRMOF-1 hybrid composite for selective H2S/CO2 capture

Ishak MAI, Jumbri K, Daud S, Abdul Rahman MB, Abdul Wahab R, Yamagishi H, et al.

J Hazard Mater, 2020 11 15;399:123008.
PMID: 32502857 DOI: 10.1016/j.jhazmat.2020.123008

The compatibility and performance of an Isoreticular Metal-Organic Frameworks (IRMOF-1) impregnated with choline-based ionic liquids (ILs) for selective adsorption of H2S/CO2, were studied by molecular dynamics (MD) simulation. Cholinium alanate ([Chl][Ala]) was nominated as the suitable IL for impregnation into IRMOF-1, consistent with the low RMSD values (0.546 nm, 0.670 nm, 0.776 nm) at three IL/IRMOF-1 w/w ratios (WIL/IRMOF-1 = 0.4, 0.8, and 1.2). The [Chl]+ and [Ala]- ion pair was located preferentially around the carboxylate group within the IRMOF-1 framework, with the latter interacting strongly with the host than the [Chl]+. Results of radius of gyration (Rg) and root mean square displacement (RMSD) revealed that a ratio of 0.4 w/w of IL/IRMOF-1 (Rg = 1.405 nm; RMSD = 0.546 nm) gave the best conformation to afford an exceptionally stable IL/IRMOF-1 composite. It was discovered that the IL/IRMOF-1 composite was more effective in capturing H2S and CO2 compared to pristine IRMOF-1. The gases adsorbed in higher quantities in the IL/IRMOF-1 composite phase compared to the bulk phase, with a preferential adsorption for H2S, as shown by the uppermost values of adsorption ( [Formula: see text] = 17.954 mol L-1 bar-1) and an adsorption selectivity ( [Formula: see text] = 43.159) at 35 IL loading.

Matched MeSH terms: Costs and Cost Analysis
Physicians' experiences with HPV vaccine delivery: evidence from developing country with multiethnic populations

Wong LP

Vaccine, 2009 Mar 4;27(10):1622-7.
PMID: 19100803 DOI: 10.1016/j.vaccine.2008.11.107

Physicians' experiences in providing human papillomavirus (HPV) immunization were assessed by mailed questionnaire. Response rate of 41.4% was achieved. Malay Muslim physicians were more likely to agree that cultural sensitivity is an issue when recommending HPV vaccines. Pediatricians and family physicians were more likely to agree that acceptance is better if vaccines were recommended to prevent cervical cancer than to prevent a sexually transmitted disease. Near 70% rated success of HPV vaccines recommendation in their practice as very poor with the majority patients preferred to postpone immunization. Physicians reported cultural disparities in vaccine uptake and perceived high vaccination cost limits its use.

Matched MeSH terms: Costs and Cost Analysis
Development of a semidefined growth medium for Pedobacter cryoconitis BG5 using statistical experimental design

Ong M, Ongkudon CM, Wong CM

Prep Biochem Biotechnol, 2016 Oct 02;46(7):657-65.
PMID: 26759918 DOI: 10.1080/10826068.2015.1135447

Pedobacter cryoconitis BG5 are psychrophiles isolated from the cold environment and capable of proliferating and growing well at low temperature regime. Their cellular products have found a broad spectrum of applications, including in food, medicine, and bioremediation. Therefore, it is imperative to develop a high-cell density cultivation strategy coupled with optimized growth medium for P. cryoconitis BG5. To date, there has been no published report on the design and optimization of growth medium for P. cryoconitis, hence the objective of this research project. A preliminary screening of four commercially available media, namely tryptic soy broth, R2A, Luria Bertani broth, and nutrient broth, was conducted to formulate the basal medium. Based on the preliminary screening, tryptone, glucose, NaCl, and K2HPO4 along with three additional nutrients (yeast extract, MgSO4, and NH4Cl) were identified to form the basal medium which was further analyzed by Plackett-Burman experimental design. Central composite experimental design using response surface methodology was adopted to optimize tryptone, yeast extract, and NH4Cl concentrations in the formulated growth medium. Statistical data analysis showed a high regression factor of 0.84 with a predicted optimum optical (600 nm) cell density of 7.5 using 23.7 g/L of tryptone, 8.8 g/L of yeast extract, and 0.7 g/L of NH4Cl. The optimized medium for P. cryoconitis BG5 was tested, and the observed optical density was 7.8. The cost-effectiveness of the optimized medium was determined as 6.25 unit prices per gram of cell produced in a 250-ml Erlenmeyer flask.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Estimating direct medical costs of type 2 diabetes mellitus in the Philippines: a protocol

Ng JYS, Clement IJ, Jimeno C, Sy RA, Mirasol R, De La Pena P, et al.

BMJ Open, 2020 07 28;10(7):e025696.
PMID: 32723733 DOI: 10.1136/bmjopen-2018-025696

INTRODUCTION: Diabetes and its complications are a major cause of morbidity and mortality in the Philippines. The prevalence of diabetes in the Philippines has increased from 3.4 million in 2010 to 3.7 million in 2017. The government has formulated strategies to control this increase, for example, through its non-communicable disease prevention and control plan. However, there is scarce research on the financial burden of diabetes. Filling this gap may further help policymakers to make informed decisions while developing and implementing resource planning for relevant interventions. The primary objective of the current study is to estimate the direct medical costs associated with type 2 diabetes mellitus (T2DM).
METHODS AND ANALYSIS: This is a 1-year retrospective cohort study of patients with T2DM in 2016. Data will be collected from: (1) hospital databases from public institutions to estimate the cost of diabetes treatment and (2) physician interviews to estimate the cost of management of diabetes in outpatient care. We will perform descriptive and comparative analyses on direct medical costs and healthcare resource utilisation, stratified by the presence of diabetes-associated complications.
ETHICS AND DISSEMINATION: Research ethics board approval has been obtained from the Department of Health Single Joint Research Ethics Board and Cardinal Santos Medical Center Research Ethics Review Committee. Findings from the study will be reported in peer-reviewed scientific journals and local researcher meetings.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Cost analysis of measles in refugees arriving at Los Angeles International Airport from Malaysia

Coleman MS, Burke HM, Welstead BL, Mitchell T, Taylor EM, Shapovalov D, et al.

Hum Vaccin Immunother, 2017 05 04;13(5):1084-1090.
PMID: 28068211 DOI: 10.1080/21645515.2016.1271518

Background On August 24, 2011, 31 US-bound refugees from Kuala Lumpur, Malaysia (KL) arrived in Los Angeles. One of them was diagnosed with measles post-arrival. He exposed others during a flight, and persons in the community while disembarking and seeking medical care. As a result, 9 cases of measles were identified. Methods We estimated costs of response to this outbreak and conducted a comparative cost analysis examining what might have happened had all US-bound refugees been vaccinated before leaving Malaysia. Results State-by-state costs differed and variously included vaccination, hospitalization, medical visits, and contact tracing with costs ranging from $621 to $35,115. The total of domestic and IOM Malaysia reported costs for US-bound refugees were $137,505 [range: $134,531 - $142,777 from a sensitivity analysis]. Had all US-bound refugees been vaccinated while in Malaysia, it would have cost approximately $19,646 and could have prevented 8 measles cases. Conclusion A vaccination program for US-bound refugees, supporting a complete vaccination for US-bound refugees, could improve refugees' health, reduce importations of vaccine-preventable diseases in the United States, and avert measles response activities and costs.

Matched MeSH terms: Costs and Cost Analysis
Applicability of fluidized bed reactor in recalcitrant compound degradation through advanced oxidation processes: a review

Tisa F, Abdul Raman AA, Wan Daud WMA

J Environ Manage, 2014 Dec 15;146:260-275.
PMID: 25190594 DOI: 10.1016/j.jenvman.2014.07.032

Treatment of industrial waste water (e.g. textile waste water, phenol waste water, pharmaceutical etc) faces limitation in conventional treatment procedures. Advanced oxidation processes (AOPs) do not suffer from the limits of conventional treatment processes and consequently degrade toxic pollutants more efficiently. Complexity is faced in eradicating the restrictions of AOPs such as sludge formation, toxic intermediates formation and high requirement for oxidants. Increased mass-transfer in AOPs is an alternate solution to this problem. AOPs combined with Fluidized bed reactor (FBR) can be a potential choice compared to fixed bed or moving bed reactor, as AOP catalysts life-span last for only maximum of 5-10 cycles. Hence, FBR-AOPs require lesser operational and maintenance cost by reducing material resources. The time required for AOP can be minimized using FBR and also treatable working volume can be increased. FBR-AOP can process from 1 to 10 L of volume which is 10 times more than simple batch reaction. The mass transfer is higher thus the reaction time is lesser. For having increased mass transfer sludge production can be successfully avoided. The review study suggests that, optimum particle size, catalyst to reactor volume ratio, catalyst diameter and liquid or gas velocity is required for efficient FBR-AOP systems. However, FBR-AOPs are still under lab-scale investigation and for industrial application cost study is needed. Cost of FBR-AOPs highly depends on energy density needed and the mechanism of degradation of the pollutant. The cost of waste water treatment containing azo dyes was found to be US$ 50 to US$ 500 per 1000 gallons where, the cost for treating phenol water was US$ 50 to US$ 800 per 1000 gallons. The analysis for FBR-AOP costs has been found to depend on the targeted pollutant, degradation mechanism (zero order, 1st order and 2nd order) and energy consumptions by the AOPs.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Tobacco Use in Southeast Asia: Key Evidences for Policy Development

Efroymson D, Velasco MG

Citation: Efroymson D, Velasco MG. Tobacco Use in Southeast Asia: Key Evidences for Policy Development. Bangkok, Thailand: Southeast Asia Tobacco Control Alliance; 2007

TABLE OF CONTENTS
Acknowledgement 3
Introduction to SEATCA Research on Tobacco 4
Tobacco and Poverty: Lessons from Cambodia and Vietnam 6
Demand Analysis and Tobacco Taxes in Vietnam and Malaysia 9
ASEAN Free Trade Area and Tobacco: A Regional Summary 12
Health Costs of Tobacco 14
Socio-demographic and Psychological Trends of Youth Smoking 17
Knowledge, Attitudes, and Practice: Tobacco Use among Health Professionals, Medical Students and Monks 20
Analysis of Smoking Behavior in Cambodia 23
Women and Tobacco: Smoke_]free Homes in Cambodia, Malaysia and Vietnam 26
Women and Tobacco: Reasons for Use, and Prevention Strategies in Cambodia, Malaysia and Thailand 29

Matched MeSH terms: Costs and Cost Analysis
Fulltext Economic-statistical design of synthetic np chart with estimated process parameter

Lee MH, Khoo MBC, Chew X, Then PHH

PLoS One, 2020;15(4):e0230994.
PMID: 32267874 DOI: 10.1371/journal.pone.0230994

The economic-statistical design of the synthetic np chart with estimated process parameter is presented in this study. The effect of process parameter estimation on the expected cost of the synthetic np chart is investigated with the imposed statistical constraints. The minimum number of preliminary subgroups is determined where an almost similar expected cost to the known process parameter case is desired for the given cost model parameters. However, the available number of preliminary subgroups in practice is usually limited, especially when the number of preliminary subgroups is large. Consequently, the optimal chart parameters of the synthetic np chart are computed by considering the practical number of preliminary subgroups in which the cost function is minimized. This leads to a lower expected cost compared to that of adopting the optimal chart parameter corresponding to the known process parameter case.

Matched MeSH terms: Costs and Cost Analysis
Asian Pacific cooperative study of allogeneic bone marrow transplantation

Masaoka T, Hiraoka A, Okamoto S, Kodera Y, Cao LX, Lu DP, et al.

Int J Hematol, 1999 Oct;70(3):190-2.
PMID: 10561913

The first cooperative study of the Asian Pacific bone marrow transplantation group included 75 patients with early leukemia who received human leukocyte antigen-matched sibling bone marrow transplants and were randomized into granulocyte colony-stimulating factor and control groups. The selected patients were registered from 10 centers in six countries and areas within Asia (Beijing, Taipei, Hong Kong, Japan, Korea, and Malaysia). The incidence of grades II-IV acute graft-vs.-host disease was 22.2%, and the 2-year survival rate was 62.7%. The period of protective isolation (27.1-66.7 days), period of hospitalization (38.6-130.5 days), and medical costs for 4 months (US $10,300-US $80,803) varied considerably. Good cooperation, i.e., low rate of protocol violation or rapid and precise presentation of case reports, was obtained.

Matched MeSH terms: Costs and Cost Analysis
Affordability of newer antiseizure medications in Asian resource-limited countries

Fong SL, Thuy Le MA, Lim KS, Khosama H, Ohnmar O, Savath S, et al.

Epilepsia, 2023 Aug;64(8):2116-2125.
PMID: 37243851 DOI: 10.1111/epi.17668

OBJECTIVE: One of the objectives of the Intersectoral Global Action Plan on epilepsy and other neurological disorders for 2022 to 2031 is to ensure at least 80% of people with epilepsy (PWE) will have access to appropriate, affordable, and safe antiseizure medications (ASMs) by 2031. However, ASM affordability is a significant issue in low- and middle-income countries, preventing PWE from accessing optimal treatment. This study aimed to determine the affordability of the newer (second and third generation) ASMs in resource-limited countries in Asia.
METHODS: We conducted a cross-sectional survey by contacting country representatives in lower-middle-income countries (LMICs) in Asia, including Indonesia, Lao People's Democratic Republic (PDR), Myanmar, Philippines, Vietnam, India, Bangladesh, and Pakistan, and the upper-middle-income country Malaysia, from March 2022 to April 2022. The affordability of each ASM was calculated by dividing the 30-day ASM cost by the daily wage of the lowest paid unskilled laborers. Treatment costing 1 day's wage or less for a 30-day supply of chronic disease is considered affordable.
RESULTS: Eight LMICs and one upper-middle-income country were included in this study. Lao PDR had no newer ASM, and Vietnam had only three newer ASMs. The most frequently available ASMs were levetiracetam, topiramate, and lamotrigine, and the least frequently available was lacosamide. The majority of the newer ASMs were unaffordable, with the median number of days' wages for a 30-day supply ranging from 5.6 to 14.8 days.
SIGNIFICANCE: All new generation ASMs, whether original or generic brands, were unaffordable in most Asian LMICs.

Matched MeSH terms: Costs and Cost Analysis
Removal of boron from ceramic industry wastewater by adsorption-flocculation mechanism using palm oil mill boiler (POMB) bottom ash and polymer

Chong MF, Lee KP, Chieng HJ, Syazwani Binti Ramli II

Water Res, 2009 Jul;43(13):3326-34.
PMID: 19487007 DOI: 10.1016/j.watres.2009.04.044

Boron is extensively used in the ceramic industry for enhancing mechanical strength of the tiles. The discharge of boron containing wastewater to the environment causes severe pollution problems. Boron is also dangerous for human consumption and causes organisms' reproductive impediments if the safe intake level is exceeded. Current methods to remove boron include ion-exchange, membrane filtration, precipitation-coagulation, biological and chemical treatment. These methods are costly to remove boron from the wastewater and hence infeasible for industrial wastewater treatment. In the present research, adsorption-flocculation mechanism is proposed for boron removal from ceramic wastewater by using Palm Oil Mill Boiler (POMB) bottom ash and long chain polymer or flocculant. Ceramic wastewater is turbid and milky in color which contains 15 mg/L of boron and 2000 mg/L of suspended solids. The optimum operating conditions for boron adsorption on POMB bottom ash and flocculation using polymer were investigated in the present research. Adsorption isotherm of boron on bottom ash was also investigated to evaluate the adsorption capacity. Adsorption isotherm modeling was conducted based on Langmuir and Freundlich isotherms. The results show that coarse POMB bottom ash with particle size larger than 2 mm is a suitable adsorbent where boron is removed up to 80% under the optimum conditions (pH=8.0, dosage=40 g bottom ash/300 ml wastewater, residence time=1h). The results also show that KP 1200 B cationic polymer is effective in flocculating the suspended solids while AP 120 C anionic polymer is effective in flocculating the bottom ash. The combined cationic and anionic polymers are able to clarify the ceramic wastewater under the optimum conditions (dosage of KP 1200 B cationic polymer=100 mg/L, dosage of AP 120 C anionic polymer=50 mg/L, mixing speed=200 rpm). Under the optimum operating conditions, the boron and suspended solids concentration of the treated wastewater were reduced to 3 mg/L and 5 mg/L respectively, satisfying the discharge requirement by Malaysia Department of Environment (DOE). The modeling study shows that the adsorption isotherm of boron onto POMB bottom ash conformed to the Freundlich Isotherm. The proposed method is suitable for boron removal in ceramic wastewater especially in regions where POMB bottom ash is abundant.

Matched MeSH terms: Costs and Cost Analysis
Integrated models for shipping a vendor’s final production batch to a single buyer under linearly decreasing demand for consignment policy

Omar M, Supadi S

Sains Malaysiana, 2012;41:367-370.

This paper considers the problem of a vendor or manufacturer supplying a final production batch to a single buyer under linearly decreasing demand for a finite time horizon. The vendor manufactures the product at a finite rate and ships the output to the buyer. In this model we considered the case where the holding cost at the vendor is greater than the buyer and propose a consignment model. The objective was to minimize the total cost of stock transfer from vendor to buyer and stock holding at the vendor and the buyer. We derived the structure of the optimal solution and illustrate the proposed models with numerical examples.

Matched MeSH terms: Costs and Cost Analysis
Fulltext Economic burden of managing Type 2 diabetes mellitus: Analysis from a Teaching Hospital in Malaysia

Ismail A, Suddin LS, Sulong S, Ahmed Z, Kamaruddin NA, Sukor N

Indian J Public Health, 2017 12 9;61(4):243-247.
PMID: 29219128 DOI: 10.4103/ijph.IJPH_24_16

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease that consumes a large amount of health-care resources. It is essential to estimate the cost of managing T2DM to the society, especially in developing countries. Economic studies of T2DM as a primary diagnosis would assist efficient health-care resource allocation for disease management.
OBJECTIVE: This study aims to measure the economic burden of T2DM as the primary diagnosis for hospitalization from provider's perspective.
METHODS: A retrospective prevalence-based costing study was conducted in a teaching hospital. Financial administrative data and inpatient medical records of patients with primary diagnosis (International Classification Disease-10 coding) E11 in the year 2013 were included in costing analysis. Average cost per episode of care and average cost per outpatient visit were calculated using gross direct costing allocation approach.
RESULTS: Total admissions for T2DM as primary diagnosis in 2013 were 217 with total outpatient visits of 3214. Average cost per episode of care was RM 901.51 (US$ 286.20) and the average cost per outpatient visit was RM 641.02 (US$ 203.50) from provider's perspective. The annual economic burden of T2DM for hospitalized patients was RM 195,627.67 (US$ 62,104) and RM 2,061,520.32 (US$ 654,450) for those being treated in the outpatient setting.
CONCLUSIONS: Economic burden to provide T2DM care was higher in the outpatient setting due to the higher utilization of the health-care service in this setting. Thus, more focus toward improving T2DM outpatient service could mitigate further increase in health-care cost from this chronic disease.

Matched MeSH terms: Costs and Cost Analysis
Cost-Effectiveness Analysis of Fondaparinux vs Enoxaparin in Non-ST Elevation Acute Coronary Syndrome in Thailand

Permsuwan U, Chaiyakunapruk N, Nathisuwan S, Sukonthasarn A

Heart Lung Circ, 2015 Sep;24(9):860-8.
PMID: 25837019 DOI: 10.1016/j.hlc.2015.02.018

Non-ST elevation acute coronary syndrome (NSTE-ACS) imposes a significant health and economic burden on a society. Anticoagulants are recommended as standard therapy by various clinical practice guidelines. Fondaparinux was introduced and evaluated in a number of large randomised, controlled trials. This study therefore aimed to determine the cost-effectiveness of fondaparinux versus enoxaparin in the treatment of NSTE-ACS in Thailand.

Matched MeSH terms: Costs and Cost Analysis

Filters

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links