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  1. Yong HY, Shariff ZM, Mohd Yusof BN, Rejali Z, Bindels J, Tee YYS, et al.
    Nutr Res Pract, 2019 Jun;13(3):230-239.
    PMID: 31214291 DOI: 10.4162/nrp.2019.13.3.230
    BACKGROUND/OBJECTIVES: Little is known about the dietary patterns (DPs) of women during pregnancy. The present study aimed to identify the DPs of pregnant Malaysian women and their associations with socio-demographic, obstetric, and anthropometric characteristics.
    SUBJECTS AND METHODS: This prospective cohort study included 737 participants enrolled in Seremban Cohort Study between 2013 and 2015. Food consumption was assessed using a validated 126-food item semi-quantitative food frequency questionnaire (SFFQ) at four time-points, namely, pre-pregnancy and at each trimester (first, second, and third). Principal component analysis (PCA) was used to identify DPs.
    RESULTS: Three DPs were identified at each time point and designated DP 1-3 (pre-pregnancy), DP 4-6 (first trimester), DP 7-9 (second trimester) and DP 10-12 (third trimester). DP 1, 4, and 7 appeared to be more prudent diets, characterized by higher intakes of nuts, seeds & legumes, green leafy vegetables, other vegetables, eggs, fruits, and milk & dairy products. DP 2, 5, 8, and 11 had greater loadings of condiments & spices, sugar, spreads & creamer, though DP 2 had additional sweet foods, DP 5 and 8 had additional oils & fats, and DP 11 had additional tea & coffee, respectively. DP 3 and 6 were characterized by high protein (poultry, meat, processed, dairy, eggs, and fish), sugars (mainly as beverages and sweet foods), and energy (bread, cereal & cereal products, rice, noodles & pasta) intakes. DP 9 had additional fruits. However, DP 12 had greater loadings of energy foods (bread, cereal & cereal products, rice, noodles & pasta), sugars (mainly as beverages, and sweet foods), and good protein sources (eggs, nuts, seeds & legumes). Malays were more likely to have lower adherence (LA) for DP 1 and 10 than non-Malays. DP 2, 8, and 11 were more prevalent among Malays than non-Malays. Women with a higher education were more likely to have LA for DP 10, and women with a greater waist circumference at first prenatal visit were more likely to show LA for DP 11.
    CONCLUSIONS: DPs observed in the present study were substantially different from those reported in Western populations. Information concerning associations between ethnicity, waist circumference and education with specific DPs before and throughout pregnancy could facilitate efforts to promote healthy dietary behavior and the overall health and well-being of pregnant women.
    Study name: Seremban Cohort Study (SECOST)
    Matched MeSH terms: Demography
  2. Yusof K, Zulkifli SN
    Malays J Reprod Health, 1985;3(1):31-45.
    PMID: 12268887
    Matched MeSH terms: Demography*
  3. Al-Khateeb A, Al-Talib H, Mohamed MS, Yusof Z, Zilfalil BA
    Adv Clin Exp Med, 2013 Jan-Feb;22(1):57-67.
    PMID: 23468263
    BACKGROUND: Familial hypercholesterolemia and familial defective apo lipoprotein B are genetic disorders caused by defects in the low-density lipoprotein receptor gene and apo lipoprotein B 100 genes, respectively. The clinical phenotype of both diseases is characterized by increased plasma levels of total cholesterol and low density lipoprotein cholesterol, tendinous xanthomata, and premature coronary heart disease.
    OBJECTIVES: The aim of this study is to perform an association study between different gene sequence variants in low-density lipoprotein and apo lipoprotein B 100 genes to the clinical finding and lipid profile parameters of the study subjects.
    MATERIAL AND METHODS: A group of 164 familial hypercholesterolemic patients were recruited. The promoter region, exon 2-15 of the low density lipoprotein gene and parts of exon 26 and 29 of apo lipoprotein B 100 gene were screened by Denaturating Gradient High Performance Liquid Chromatography.
    RESULTS: For the apo lipoprotein B 100 gene, those with apo lipoprotein B 100 gene mutation have a significantly higher frequency of cardiovascular disease (P = 0.045), higher low density lipoprotein cholesterol and total cholesterol: high density lipoprotein cholesterol ratio than those without mutation (P = 0.03 and 0.02, respectively). For the low density lipoprotein gene defect those with frame shift mutation group showed the worst clinical presentation in terms of low density lipoprotein cholesterol level and cardiovascular frequency.
    CONCLUSIONS: There was a statistically significant association between mutations of low density lipoprotein gene and apo lipoprotein B 100 genes and history of cardiovascular disease, younger age of presentation, family history of hyperlipidemia, tendon xanthoma and low density lipoprotein cholesterol level.
    Study site: Cardiology Clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia
    Matched MeSH terms: Demography
  4. Dickinson L, Noble H, Gardner E, Puad ASA, Zakaria WNFW, Zerega NJC
    PeerJ, 2020;8:e9897.
    PMID: 33005490 DOI: 10.7717/peerj.9897
    Limestone karsts of Southeast Asia can harbor high levels of endemism, but are highly fragmented, increasingly threatened, and their biodiversity is often poorly studied. This is true of the Padawan Limestone Area of Sarawak, Malaysia, home to the endemic Artocarpus annulatus, the closest known wild relative of two important and underutilized fruit tree crops, jackfruit (A. heterophyllus) and cempedak (A. integer). Identifying and conserving crop wild relatives is critical for the conservation of crop genetic diversity and breeding. In 2016 and 2017, five A. annulatus populations were located, and leaf material, locality information, and demographic data were collected. Microsatellite markers were used to assess genetic diversity and structure among populations, and to compare levels of genetic diversity to closely related congeneric species. Results indicate no evidence of inbreeding in A. annulatus, and there is no genetic structure among the five populations. However, diversity measures trended lower in seedlings compared to mature trees, suggesting allelic diversity may be under threat in the youngest generation of plants. Also, genetic diversity is lower in A. annulatus compared to closely related congeners. The present study provides a baseline estimate of A. annulatus genetic diversity that can be used for comparison in future studies and to other species in the unique limestone karst ecosystems. Considerations for in situ and ex situ conservation approaches are discussed.
    Matched MeSH terms: Demography
  5. Zarei M, Msl H, Mohd Taib MN, Zarei F
    Glob J Health Sci, 2014 Nov;6(6):185-97.
    PMID: 25363094 DOI: 10.5539/gjhs.v6n6p185
    The aim or this study was to determine factors associated with body weight status among Iranian adolescents in the two Secondary Schools run by the Embassy in Kuala Lumpur.
    Matched MeSH terms: Demography
  6. Villabona-Arenas CJ, Zanotto PM
    Infect Genet Evol, 2011 Jul;11(5):878-85.
    PMID: 21335103 DOI: 10.1016/j.meegid.2011.02.007
    Dengue virus type 4 (DENV-4) circulates in tropical and subtropical countries from Asia and the Americas. Despite the importance of dengue virus distribution, little is known about the worldwide viral spread. Following a Bayesian phylogenetic approach we inferred the evolutionary history of 310 isolates sampled from 37 countries during the time period 1956-2008 and the spreading dynamics for genotypes I and II. The region (tropical rainforest biome) comprised by Malaysia-Thailand was the most likely ancestral area from which the serotype has originated and spread. Interestingly, cross-correlation analysis on demographic time series with the Asian sequences showed a statistically significant negative correlation that could be suggestive of competition among genotypes within the same serotype.
    Matched MeSH terms: Demography
  7. Rafi Mahmoud Alnjadat, Aasim Adnan, Zalina Ismail
    MyJurnal
    Aim: The objective of the present study was to assess the validity and reliability of Malay version of the QOLLTI-F questionnaire.
    Methods: A total of 80 Malay caregivers of cancer patients in an outpatient oncology clinic were enrolled in this study. A translated QOLLTI-F questionnaire of 16 items was used in order to assess their quality of life. Demographic characteristics were recorded. Both face and content validity of the translated version were carried out by professionals and the construct validity of the questionnaire was assessed by exploratory factor analysis.
    Results: Exploratory factor analysis led to the extraction of seven factors and this was consistent with the English version. Cronbach Alpha coefficient showed good consistency of the questions within the sub-scales (Cronbach's alpha > 0.7).
    Conclusion: This study was confined to a Malay population, and the analyses were potentially limited by a small sample size .Nevertheless, the translated questionnaire demonstrated valid and reliable psychometric properties when administered to Malay caregivers. Future studies are needed to see if this instrument can fit other samples in different settings and populations.
    Study site: Oncology clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia
    Matched MeSH terms: Demography
  8. Al-Naggar, Redhwan Ahmed, Al-Jashamy, Karim, Ramli Musa, Zaleha Mohd Isa
    ASEAN Journal of Psychiatry, 2010;11(1):6-12.
    MyJurnal
    Objective: To determine the knowledge, attitude and practice (KAP) of sleep among medical students of IIUM towards and to determine the impact of socio-demographic data on the knowledge, attitude and practice. Methods: A cross-sectional study was carried out among 106 students from first, second and third year medical students of IIUM. Verbal consent was taken from the students who were willing to take part in this study. Student knowledge about sleep was studied using a questionnaire. Results: A total of 106 medical
    students completed the survey, there were 54 female and 52 male. The mean age of the students was 20 ± 0.56 and ranged from 18 to 22 years. In terms of their sleep knowledge, the mean ± SD knowledge, attitude and practice scores were 81.8 ± 16.8, 65.9 ±15.3 and 176 ± 26.3 respectively. In univariate analysis, there was a significant difference between parents’ marital status regarding knowledge of the students (p = 0.03). There was a significant difference between gender regarding attitude of the students (p=0.05). In
    multivariate analysis, gender and smoking status were significantly affected the overall KAP. Conclusion: This study showed that sleep medicine knowledge was generally low among medical students. Therefore, educational strategies to improve knowledge regarding sleep-related problems and the development of proper sleep practices among medical students are needed.
    Matched MeSH terms: Demography
  9. Alina, T.I., Norbanee, T.H., Hashim, M.H., Zaki, N.M.S.
    MyJurnal
    A cross»sectional study was conducted to determine the knowledge on family planning among Malay women who delivered at Hospital Universiti Sains Malaysia (H USM), Kelantan and their husbands. Three hundred and fifty five women were selected by systematic random sampling. An interview-guided questionnaire that included infomation on socio-demographic, obstetric and knowledge on family planning was conducted to the women and self-administered questionnaire was given to their husbands. There were 15 questions on knowledge which were validated prior to the study. More than half of the women (53.5%) and the husbands (57.7%) had poor knowledge score (less than 75%) on family planning. A majority (86.8%) of the women and 87.9% of the husbands knew the optimal age of a woman to be pregnant, but very few (3.4%) of the women and Ss 1% of the husbands could answer correctly all the questions on the effects of poor spacing. The level of knowledge on family planning among Malay women who delivered at H USM and their husbands were poor. Therefore, new and improved health education materiab and programmes are needed, to target both the women and their husbands.
    Matched MeSH terms: Demography
  10. Thanigasalam T, Reddy SC, Zaki RA
    J Ophthalmic Vis Res, 2016 4 7;10(4):375-84.
    PMID: 27051481 DOI: 10.4103/2008-322X.158892
    PURPOSE: Cataract surgery is the most common intraocular surgery performed all over the world and has advanced technically in recent years. As in all surgeries, complications are unavoidable. Herein we report factors associated with complications and visual outcomes of cataract surgery.

    METHODS: This retrospective cohort study included data of 1,632 cataract surgeries performed from 2007 to 2010 which was obtained from the cataract registry of the Malaysian National Eye Database. Demographic features, ocular and systemic comorbidites, grade of surgeon expertise and duration of surgery, type of anesthesia, intraoperative and postoperative complications, and the type of intraocular lens were recorded. Best corrected visual acuities were compared before and after the operation.

    RESULTS: Mean patient age was 66.9 years with equal gender distribution. The majority of subjects had age related cataracts. Phacoemulsification was done faster than other surgeries, especially by specialist surgeons. History of prior ocular surgery and operations performed under general anesthesia were associated with greater complications. Phacoemulsification was associated with less complications and better visual outcomes. The age and etiology of cataract did not affect complications. Malays, absence of ocular comorbidities, left eyes and eyes operated under local anesthesia were more likely to experience more visual improvement. Gender, age, cause of cataract, systemic comorbidities and surgeon expertise as well as intra-and postoperative complications did not affect the visual outcomes.

    CONCLUSION: Phacoemulsification had good visual outcomes in cataract surgery. Duration of surgery, expertise of the surgeon and complications did not affect the visual outcomes.

    Matched MeSH terms: Demography
  11. Ng, C.G., Nurasikin, M.S., Loh, H.S., Yee, Anne H.A., Zainal, N.Z.
    MyJurnal
    Introduction: There is increasing awareness of the contribution of perceived social support (PSS) to emotional and physical well-being. Numerous scales measuring PSS have been developed, including the widely used Multidimensional Scale of Perceived Social Support (MSPSS). The psychometric properties of the MSPSS have been demonstrated in diverse samples, however mostly are conducted in English. Malay is the official languange in Malaysia, and this study was conducted to provide evidence of the validity and reliability of a Malay version MSPSS (MSPSS-M) suited for our population.
    Methods: This is a cross sectional study. The socio-demographic and clinical information of the selected patients from psychiatric outpatient clinic over a 3-month period, were obtained via pre-designed questionnaire, interviews and medical records. Assessment of psychiatric symptoms and social support were measured by various instruments including the Brief Psychiatric Rating Scale (BPRS-E), Depressive, Anxiety and Stress Scale (DASS) and MSPSS-M.
    Results: Data were reported for 228 psychiatric outpatients with the mean age of 40.3 years old. The 3-factor structure of the MSPSS-M (significant others, family, and friends) fitted the data well. The MSPSS-M showed good internal consistency (Cronbach α of 0.89) and validity. The scores of the total subscales for MSPSS-M were negatively correlated with the depression subscale in DASS (P < 0.05). BPRS was negatively correlated with significant others (P < 0.01) compared to the other two subscales in MSPSS-M.
    Conclusions: The Malay version MSPSS (MSPSS-M) is a psychometrically valid instrument with high internal consistency, which is useful in assessing perceived social support in Malaysian population.

    Study site: psychiatric clinic, University Malaya
    Medical Center (UMMC)
    Matched MeSH terms: Demography
  12. Zain SM, Mohamed Z, Jalaludin MY, Fauzi F, Hamidi A, Zaharan NL
    Pharmacogenet Genomics, 2015 Oct;25(10):501-10.
    PMID: 26240981 DOI: 10.1097/FPC.0000000000000164
    Orexigenic actions mediated by neuropeptide-Y (NPY) promote body weight regulation. Genetic variations in the NPY gene could therefore influence susceptibility to obesity, but results have been conflicting. We have carried out, for the first time, a case-control study to examine the effect of NPY rs16147 and rs5574 variants with the risk of obesity in Asians and also a meta-analysis to summarize the effect of these variants including that of the widely studied rs16139.
    Matched MeSH terms: Demography
  13. Hafizah I, Tengku Alina TI, Suhaily MH, Zaharah S
    MyJurnal
    This community-based, cross-sectional study aimed to identify the factors associated with
    postpartum family planning use among a cohort of women with recent caesarean delivery in a state with the
    lowest contraceptive use in Malaysia. Materials and Methods: A total of 281 women aged between 18-49
    years old who had caesarean delivery in government tertiary centres in Kelantan from January until April
    2017 were enrolled in this study. The study was conducted from January until April 2018. Women were
    selected through stratified random sampling with probability proportional to size. Data were collected
    through a validated structured questionnaire. The main outcome was binary (postpartum family planning use
    or non-use). The factors included socio-demographic details, reproductive history, previous contraceptive
    use, contraceptive health education received, knowledge, and social support. Simple and multiple logistic
    regression were conducted to identify significant determinants of postpartum family planning use. Results:
    The factors associated with postpartum family planning use included a secondary and below education level
    of women (AOR= 2.37, 95% CI (1.05, 5.34)), previous contraceptive use (AOR= 9.82, 95% CI (4.81, 20.06)),
    individual health education (AOR= 4.19, 95% CI (1.23, 14.30)), higher knowledge score (AOR= 1.12, 95% CI
    (1.03, 1.23)), and higher social support score (AOR= 1.09, 95% CI (1.03, 1.16)). Conclusions: here remains a
    need to enhance personalised contraceptive counselling in the primary care setting as well as to promote
    longer acting reversible contraceptive methods.
    Matched MeSH terms: Demography
  14. Raza Kazmi SM, Iqbal Z, Muneer MU, Riaz S, Zafar MS
    Eur J Dent, 2018 8 28;12(3):375-379.
    PMID: 30147402 DOI: 10.4103/ejd.ejd_232_18
    Objective: The current study aimed to assess the knowledge and practice of pontic design selection by the general dental practitioners (GDPs) in the light of contemporary guidelines.

    Materials and Methods: This cross-sectional study was conducted among the GDPs of Karachi. A questionnaire was designed to collect data from 100 GDPs. The questionnaire included general/demographic information (practitioner's education, experience, and place of practice) and an average number of fixed prosthesis constructed by the GDP. The questionnaire was further categorized to evaluate the knowledge/practice of pontic design selection and latest recommendations.

    Results: For the maxillary anterior segment, the ridge lap pontic was the most common (32%) followed by the modified ridge lap (28%). In the maxillary posterior segment, the ridge lap pontic was the most common (37%) followed by sanitary design (34%). For the mandibular anterior segment, the modified ridge lap (50%) was the most common followed by ridge lap pontic (17%). In case of the mandibular posterior segment, the sanitary design (34%) was the most common followed by ridge lap pontic (30%).

    Conclusions: The pontic design selection for the fixed prosthesis is a neglected domain. The contemporary guidelines are not followed with full spirit by the GDPs leading to wide variations in the pontic design selection.

    Matched MeSH terms: Demography
  15. He YZ, Yusop FD
    Data Brief, 2020 Apr;29:105230.
    PMID: 32123703 DOI: 10.1016/j.dib.2020.105230
    This dataset contains demographic information of 355 respondents and a validated 32-items Stages of Concerns Questionnaire (SoCQ). The SoCQ questionnaire was developed based on the Concerns-Based Adoption Model (CBAM) which measures seven stages of concerns as the variables. They are unconcerned, informational, personal, management, consequence, collaboration and refocusing. The data was firstly tested with normality, followed by validity checking using confirmatory factor analysis (CFA). It is useful for policy makers and stakeholders to have a thorough understanding about teachers' concerns on the use of the e-learning platform and thus, design suitable interventions to smoothen the adoption process of using the technology. This set of data could be used in a multi-racial developing country for more complex analyses.
    Matched MeSH terms: Demography
  16. Yudin ZM, Yaacob LH, Hassan NB, Ismail SB, Draman N, Yusoff SSM
    Malays J Med Sci, 2017 May;24(3):44-50.
    PMID: 28814932 MyJurnal DOI: 10.21315/mjms2016.24.3.6
    BACKGROUND: Statins are a class of potent drugs that can be used to reduce cholesterol, especially low-density lipoprotein cholesterol (LDL-C). However, their effectiveness is limited if adherence to treatment is poor. The objectives of the study are to estimate the proportion of diabetic patient who has achieved LDL-C goal and to determine the association of LDL-C achievement with socio demographic factors and statin therapy adherence.

    METHODS: This is a cross-sectional study involving 234 patients with type 2 diabetes mellitus (T2DM) and dyslipidaemia attending an outpatient clinic in a hospital in Kelantan. Interviews and self-administered questionnaires were used to determine their sociodemographic and clinical characteristics. Adherence to therapy was assessed using the Medication Compliance Questionnaire (MCQ). The associations between the achievement of LDL targets and sociodemographic/clinical factors, including adherence, were analysed with simple logistic regression.

    RESULTS: About 37.6% of patients achieved their LDL-C target. The percentage of patients who adhered to statin use was 98.3%, and 20.5% of these patients reported full adherence. There was no significant association between achievement of LDL-C targets with adherence or any other sociodemographic factors, such as age, gender and educational or economic status (all P-value < 0.05).

    CONCLUSION: Despite a high level of adherence, the majority of patients failed to achieve LDL-C targets. More concerted efforts are needed to improve this.

    Study site: primary
    care clinic in Hospital Universiti Sains Malaysia,
    Matched MeSH terms: Demography
  17. Omar A, Jalil JA, Shakrin NM, Ngu LH, Yunus ZM
    Data Brief, 2019 Aug;25:104377.
    PMID: 31516928 DOI: 10.1016/j.dib.2019.104377
    This article contains information related to a recent study "Selective screening for detection of mucopolysaccharidoses (MPS) in Malaysia; A Two-year Study" Affandi et al., 2019. Any patient registered under government healthcare facilities in Malaysia and fit at least two inclusion criteria were included in this selective screening. Urine and blood from these high risk patients were obtained and analysed for glycosaminoglycans (GAGs) level before characterization using high resolution electrophoresis (HRE). Thereafter, enzyme assay for different types of MPS based on result of HRE were determined using specific substrate. Demographic data as well as laboratory findings were tabulated and analysed. The data of this study demonstrate between clinical presentation and laboratory findings among high risk patients of MPS and can be employed to improve diagnosis of MPS.
    Matched MeSH terms: Demography
  18. Martadza M, Saedon UI, Darus N, Badli TST, Ghazalan SA, Yunus WMAWM
    Malays J Med Sci, 2019 Nov;26(6):111-119.
    PMID: 31908592 MyJurnal DOI: 10.21315/mjms2019.26.6.11
    Background: This descriptive study identifies the demographic characteristics and patterns of referral to clinical psychology services, which include types of diagnosis, types of referral and source of referrals in child, adolescent, adult and geriatric cases in Malaysia.

    Methods: We utilised 2,179 referrals between January and December 2015 from six general hospitals and three mental health institutions that provide clinical psychology services.

    Results: The percentage of male referrals (60.3%) is higher than that of female referrals (39.7%). Adult cases had the highest percentage of referrals (48.2%). Children (48.8%) and adolescent (28.1%) cases were mainly referred for psychological assessment. Meanwhile, adult cases (74.8%) were mainly referred for psychological intervention. Neurodevelopmental disorders was the diagnosis with the highest percentage of referrals recorded (41.4%), followed by depressive disorders (13.3%) and anxiety disorders (12.7%), and the combination of other disorders. Psychiatrists provided the highest number of referrals (82.2%), which is unsurprising as both fields are closely related.

    Conclusion: Clinical psychology services within the Ministry of Health (MOH) Malaysia play an important role in mental health care.

    Matched MeSH terms: Demography
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