Displaying publications 1 - 20 of 87 in total

Abstract:
Sort:
  1. Abdul Rahim FS, Mohamed AM, Marizan Nor M, Saub R
    Acta Odontol Scand, 2014 Nov;72(8):999-1004.
    PMID: 25029211 DOI: 10.3109/00016357.2014.936036
    The purpose of this cross-sectional study was to assess the legal representatives' perceptions on dental care access of individuals with Down syndrome (DS) compared to their non-DS siblings in Peninsular Malaysia.
    Matched MeSH terms: Eye Diseases/therapy
  2. Vannas A, Hogan MJ, Wood I
    Am J Ophthalmol, 1975 Feb;79(2):211-9.
    PMID: 46719
    Eleven corneal specimens from nine patients with Salzmann's nodular degeneration of the cornea, together with all available clinical information, were collected for this study. The specimens were examined by light and electron microscopy. An antecedent keratitis was diagnosed by history and microscopic findings in every case. The corneal epithelium showed degenerative changes, its thickness varied, and in nodular areas it often consisted of only a single layer of flattened epithelial cells by light microscopy. Bowman's membrane was missing over the nodules, and in this zone there was excessive secretion of a basement membrane-like material. Hyaline degeneration of collagen, cellular debris, and electron-dense hyaline deposits were seen in the collagen of the nodules. The number of fibrocytes in the nodules varied from many that were active to a few that were degenerating. External irritation because of poor epithelial protection was interpreted as a causative factor, although other tissue repair mechanisms may also have played a role.
    Matched MeSH terms: Eye Diseases/pathology
  3. Khalid BA, Ng ML
    Ann Acad Med Singap, 1991 Mar;20(2):273-6.
    PMID: 1883189
    Thyroid eye disease is autoimmune in nature and associated with Graves' Disease. Autoantibodies to the 64 kDa antigen in thyroid membranes cross-react to the 64 kDa proteins in human eye muscle membranes. Antibody dependent cell mediated cytotoxicity against eye muscle cells are also found in patients with thyroid eye disease. The purpose of this paper is to review the treatment available and to share the authors' experience using cyclosporin A. In the majority of cases, thyroid eye disease is mild, manifest only as bilateral or unilateral proptosis, with/without grittiness of the eyes. This is usually treated conservatively with eye drops. If proptosis is more severe and there is incomplete closure of eyelids, epiphora and conjunctival injection, then lateral tarrsorrhaphy is usually effective, combined with use of eye pads and eye drops. The problem of diplopia can be treated conservatively with special lenses, or with surgical correction of tethered muscles. However when proptosis is severe, with raised intraocular pressure, severe chemosis and danger of blindness, then the choice of therapy is controversial: rapid decompression by surgical means or use of high doses of prednisolone. Most prefer prednisolone therapy initially, surgical decompression if it fails. Various other methods have been tried, aimed at the immunological nature of the disease, namely plasmapheresis, radiotherapy and immunosuppressive drugs such as cyclosporin, with variable success. Our experience with cyclosporin had been mixed and inconclusive.
    Matched MeSH terms: Eye Diseases/etiology; Eye Diseases/immunology; Eye Diseases/therapy*
  4. Ngah NF, Moktar N, Isa NH, Selvara S, Yusof MS, Sani HA, et al.
    Asia Pac J Clin Nutr, 2002;11(2):88-91.
    PMID: 12074186
    This study determined the prevalence of ocular manifestation of vitamin A deficiency in Orang Asli (Aborigine) children. Night blindness was found in 16.0% of the children, conjunctiva xerosis in 57.3%, Bitot's spot in 2.8%, corneal xerosis in 0.5% and corneal scars in 5.6%. These findings show that history of night blindness had sensitivity, specificity and predictive value (positive) of 47.2, 98.1 and 96.2%, respectively, compared with the standard diagnosis procedure using luxometer readings.
    Matched MeSH terms: Eye Diseases/etiology*
  5. Muzaliha MN, Adil H, Ibrahim M, Shatriah I
    BMC Ophthalmol, 2010;10:18.
    PMID: 20537193 DOI: 10.1186/1471-2415-10-18
    Candida glabrata endophthalmitis following keratoplasty is rare and almost always associated with positive donor rim culture.
    Matched MeSH terms: Eye Diseases/etiology; Eye Diseases/ultrasonography
  6. Aryasit O, Ng DS, Goh ASC, Woo KI, Kim YD
    BMC Ophthalmol, 2016 Jul 07;16:94.
    PMID: 27387333 DOI: 10.1186/s12886-016-0287-0
    BACKGROUND: Porous polyethylene implants are commonly used in orbital blowout fracture repair because of purported biocompatibility, durability, and low frequency of complications. Delayed inflammation related to porous polyethylene sheet implants is very rare and no case series of this condition have been reported.

    CASE PRESENTATION: This is a retrospective review of clinical presentations, radiographic findings, histopathological findings, treatments, and outcomes of patients who developed delayed complications in orbital blowout fracture repair using porous polyethylene sheets. Four male patients were included with a mean age of 49 years (range 35-69 years). Blowout fracture repair was complicated with implant-related inflammation 10 months, 2 years, 3 years, and 8 years after surgery. Chronic and subacute orbital inflammatory signs were noted in two patients and acute fulminant orbital inflammation was found in two patients. Three patients developed peri-implant abscesses and one patient had a soft tissue mass around the implant. All patients underwent implant removal and two of these patients with paranasal sinusitis had sinus surgery. Histopathological findings revealed chronic inflammatory changes with fibrosis, and one patient had foreign body granuloma with culture positive Staphylococcus aureus.

    CONCLUSIONS: Delayed complications with porous polyethylene sheets used in orbital blowout fracture repair may occur many years following the initial surgery in immunocompetent patients. Low-grade or fulminant inflammation could complicate blowout fracture repair related with the implant.

    Matched MeSH terms: Eye Diseases/etiology*
  7. Highet HC
    Br Med J, 1896 Nov 7;2(1871):1380-1381.
    PMID: 20756574
    Matched MeSH terms: Eye Diseases
  8. Leow SN, Bastion ML
    BMJ Case Rep, 2013;2013.
    PMID: 23645703 DOI: 10.1136/bcr-2013-009664
    To describe a case of familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager.
    Matched MeSH terms: Eye Diseases, Hereditary/diagnosis*; Eye Diseases, Hereditary/surgery
  9. Lim HH, Domala Z, Joginder S, Lee SH, Lim CS, Abu Bakar CM
    Br J Ind Med, 1984 Nov;41(4):445-9.
    PMID: 6498108 DOI: 10.1136/oem.41.4.445
    A study was carried out to determine the health effects of rice husk dust in Malaysian rice millers. The study population consisted of 122 male Malay workers from three rice mills, with 42 controls of similar age, sex, ethnic group, and agricultural work background. Interviews using standardised questionnaires, physical examination, total and differential white cell counts, chest radiographs, and lung function tests were performed on each of the millers and the controls. Environmental dust monitoring was also carried out in the three rice mills. Clinical, haematological, and radiological findings suggest that a distinct clinical syndrome seems to be associated with exposure to rice husk dust. The manifestations of this "rice millers' syndrome" include acute and chronic irritant effects affecting the eyes, skin, and upper respiratory tract; allergic responses such as nasal catarrh, tightness of chest, asthma, and eosinophilia; and radiological opacities in the chest, probably representing early silicosis or extrinsic allergic alveolitis.
    Matched MeSH terms: Eye Diseases/etiology
  10. Mishra D, Gade S, Glover K, Sheshala R, Singh TRR
    Curr Eye Res, 2023 Feb;48(2):208-218.
    PMID: 36036478 DOI: 10.1080/02713683.2022.2119254
    Purpose: Intravitreal administration of drug molecules is one of the most common routes for treating posterior segment eye diseases. However, the properties of vitreous humour changes with the time. A number of ocular complications such as liquefaction of the vitreous humour, solidification of the vitreous humour in the central vitreous cavity and detachment of the limiting membrane due to the shrinking of vitreous humour are some of the factors that can drastically affect the efficacy of therapeutics delivered via intravitreal route. Although significant research has been conducted for studying the properties of vitreous humour and its changes during the ageing process, there have been limited work to understand the effect of these changes on therapeutic efficacy of intravitreal drug delivery systems. Therefore, in this review we discussed both the coomposition and characteristics of the vitreous humour, and their subsequent influence on intravitreal drug delivery.Methods: Articles were searched on Scopus, PubMed and Web of Science up to March 2022.Results: In this review, we discussed the biological composition and biomechanical properties of vitreous humour, methods to study the properties of vitreous humour and the changes in these properties and their relevance in ocular drug delivery field, with the aim to provide a useful insight into these aspects which can aid the process of development of novel intravitreal drug delivery systems.Conclusions: The composition and characteristics of the vitreous humour, and how these change during natural aging processes, directly influence intravitreal drug delivery. This review therefore highlights the importance of understanding the properties of the vitreous and identifies the need to achieve greater understanding of how changing properties of the vitreous affect the therapeutic efficacy of drugs administered for the treatment of posterior eye diseases.
    Matched MeSH terms: Eye Diseases*
  11. Jeganathan VS, Palanisamy M
    Curr Opin Ophthalmol, 2010 May;21(3):213-7.
    PMID: 20393292 DOI: 10.1097/ICU.0b013e32833867ad
    Adult ocular stem cells have the potential to restore vision in patients previously deemed incurable. This review summarizes strides in stem cell research and stumbling blocks that must be overcome to enable treatment viability in ophthalmology.
    Matched MeSH terms: Eye Diseases/therapy*
  12. Shirley Ding SL, Leow SN, Munisvaradass R, Koh EH, Bastion ML, Then KY, et al.
    Eye (Lond), 2016 Oct;30(10):1293-1309.
    PMID: 27285322 DOI: 10.1038/eye.2016.94
    Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible only in producing red blood cells in our body. However, with the discovery of the presence of EPO and EPO receptors in the retinal layers, the EPO seems to have physiological roles in the eye. In this review, we revisit the role of EPO in the eye. We look into the biological role of EPO in the development of the eye and the physiologic roles that it has. Apart from that, we seek to understand the mechanisms and pathways of EPO that contributes to the therapeutic and pathological conditions of the various ocular disorders such as diabetic retinopathy, retinopathy of prematurity, glaucoma, age-related macular degeneration, optic neuritis, and retinal detachment. With these understandings, we discuss the clinical applications of EPO for treatment of ocular disorders, modes of administration, EPO formulations, current clinical trials, and its future directions.
    Matched MeSH terms: Eye Diseases/drug therapy*; Eye Diseases/etiology; Eye Diseases/physiopathology; Eye Diseases/prevention & control
  13. Chidambaram S
    Family Physician, 1991;3:52-54.
    Matched MeSH terms: Eye Diseases
  14. Loh KY, Tee CT
    Family Physician, 2005;13:18-18.
    Matched MeSH terms: Eye Diseases
  15. Subramaniam SC
    Family Physician, 1989;1:24-26.
    Matched MeSH terms: Eye Diseases
  16. Hari K
    Family Practitioner, 1984;7:27-30.
    Matched MeSH terms: Eye Diseases
  17. Lim ASM
    Family Practitioner, 1981;4:61-62.
    Matched MeSH terms: Eye Diseases
  18. Mahendraraj K
    Family Practitioner, 1987;10(1):34-39.
    Matched MeSH terms: Eye Diseases
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links