MyMedR

Fulltext A case of gumma of the ciliary region

Highet HC

Br Med J, 1896 Nov 7;2(1871):1380-1381.

PMID: 20756574

Matched MeSH terms: Eye Diseases

A comparative analysis of avoidable causes of childhood blindness in Malaysia with low income, middle income and high income countries

Koay CL, Patel DK, Tajunisah I, Subrayan V, Lansingh VC

Int Ophthalmol, 2015 Apr;35(2):201-7.

PMID: 24652461 DOI: 10.1007/s10792-014-9932-x

To determine the avoidable causes of childhood blindness in Malaysia and to compare this to other middle income countries, low income countries and high income countries. Data were obtained from a school of the blind study by Patel et al. and analysed for avoidable causes of childhood blindness. Six other studies with previously published data on childhood blindness in Bangladesh, Ethiopia, Nigeria, Indonesia, China and the United Kingdom were reviewed for avoidable causes. Comparisons of data and limitations of the studies are described. Prevalence of avoidable causes of childhood blindness in Malaysia is 50.5 % of all the cases of childhood blindness, whilst in the poor income countries such as Bangladesh, Ethiopia, Nigeria and Indonesia, the prevalence was in excess of 60 %. China had a low prevalence, but this is largely due to the fact that most schools were urban, and thus did not represent the situation of the country. High income countries had the lowest prevalence of avoidable childhood blindness. In middle income countries, such as Malaysia, cataract and retinopathy of prematurity are the main causes of avoidable childhood blindness. Low income countries continue to struggle with infections such as measles and nutritional deficiencies, such as vitamin A, both of which are the main contributors to childhood blindness. In high income countries, such as the United Kingdom, these problems are almost non-existent.

Matched MeSH terms: Eye Diseases/complications; Eye Diseases/epidemiology*

A day in the life of an opthalmologist

Viswalingam A

Malayan Medical Journal, 1935;10:113-5.

Matched MeSH terms: Eye Diseases

A preliminary survey of ophthalmological practice in Singapore

Williamson AD

Journal of the Malaya Branch of the British Medical Association, 1937;1:173-83.

Matched MeSH terms: Eye Diseases

Fulltext A review of 115 cases of enucleation in west Malaysia

Narasimha G, Chandran S

Singapore Med J, 1977 Dec;18(4):224-7.

PMID: 614696

115 cases of enucleated eyes in the University Hospital, Kuala Lumpur, are reviewed. Trauma 36, Glaucoma 28, tumours and suspected tumours 24 and Infection 17 are the main causes. Trauma caused mainly by sticks, stones and sharp Instruments Is largely confined to the age group below 30. Primary narrow angle glaucoma accounts for 5 cases. The main types of secondary glaucomas are due to aphakia (12) and a hypermature lens (7) . Two thirds of the tumours are retinoblastomas and this Is the commonest cause of removal below the age of 5 years. There are 4 cases 01 malignant melanoma, all are Chinese. The average age Incidence Is 43 years, which appears to be a decade earlier than in the Caucasians. Preventive measures especially In regards to trauma and glaucoma are discussed.

Matched MeSH terms: Eye Diseases/surgery*

Abstracts of the 20th Asia Pacific Academy of Ophthalmology Congress, Kuala Lumpur, Malaysia, 27-31 March 2005

Am J Ophthalmol, 2005 Apr;139(4 Suppl):S1-71.

PMID: 16729358

Matched MeSH terms: Eye Diseases*

Fulltext Antioxidant enzymes in tears among Malay age-related macular degeneration patients

Yi Ni Koh, Embong Zunaina, Ahmad Tajudin Liza-Sharmini, Che Badariah Abd-Aziz, Che Hussin Che-Maraina, Mei Fong Chong, et al.

Malaysian Journal of Medicine and Health Sciences, 2020;16(2):149-156.

MyJurnal

Introduction: Age-related macular degeneration (ARMD) is an ocular degenerative disorder that associated with impairment of central vision. Oxidative stress plays an important role in the pathogenesis of ARMD. The aim of this study was to determine the level of antioxidant enzymes (catalase and glutathione peroxidase) in tears among Malay ARMD patients. Methods: A cross sectional study was conducted between September 2015 and November 2017 among Malay ARMD patients. Schirmer paper was used to collect the tear samples. The level of catalase and glu- tathione peroxidase level in tears was evaluated using commercially available oxidative stress marker kits. Results: A total of 136 Malay ARMD patients were recruited into the study with 68 controls. Mean tear catalase and gluta- thione peroxidase levels were significantly lower in ARMD patients (1348.97 SD 109.11 µM and 453.87 SD 41.96 U/L respectively) as compared to the control group (1453.38 SD 38.87 µM and 502.28 SD 34.29 U/L respectively) (P

Matched MeSH terms: Eye Diseases

Audit of Web-based telemedicine in ophthalmology

Kennedy C, Bowman R, Fariza N, Ackuaku E, Ntim-Amponsah C, Murdoch I

J Telemed Telecare, 2006;12(2):88-91.

PMID: 16539756

A Web-based service was set up to link subspecialist ophthalmologists with those seeking advice on particular clinical problems in ophthalmology. The service operated between countries, with centres in Malaysia, Ghana, Tanzania, South Africa and Gambia seeking advice from Moorfields Eye Hospital in the UK. It also operated within country, where a rural clinic in The Gambia sought advice from the central hospital on difficult cases or cases for possible referral. Provision of Web access and training in image capture and manipulation were undertaken in each participating centre. During the first 12 months, 132 cases were posted to the Website from five of the six centres participating. The rate of case referral rose to about 12-14 cases per month by the end of the study. Overall, 24% of referrals did not use images. In the first four months the response time was 13 days, and in the last four months it was three days. Most cases were answered with a single response from the specialist. The main problem was the amount of Internet down-time in each of the locations. The main benefit was safe and reliable access to specialist advice for practitioners.

Matched MeSH terms: Eye Diseases/diagnosis*; Eye Diseases/therapy*

Automatic tracing of optic disc and exudates from color fundus images using fixed and variable thresholds

Reza AW, Eswaran C, Hati S

J Med Syst, 2009 Feb;33(1):73-80.

PMID: 19238899

The detection of bright objects such as optic disc (OD) and exudates in color fundus images is an important step in the diagnosis of eye diseases such as diabetic retinopathy and glaucoma. In this paper, a novel approach to automatically segment the OD and exudates is proposed. The proposed algorithm makes use of the green component of the image and preprocessing steps such as average filtering, contrast adjustment, and thresholding. The other processing techniques used are morphological opening, extended maxima operator, minima imposition, and watershed transformation. The proposed algorithm is evaluated using the test images of STARE and DRIVE databases with fixed and variable thresholds. The images drawn by human expert are taken as the reference images. The proposed method yields sensitivity values as high as 96.7%, which are better than the results reported in the literature.

Matched MeSH terms: Eye Diseases/diagnosis*

Fulltext Awareness and knowledge of common eye diseases among the academic staff (non-medical faculties) of University of Malaya

Chew YK, Reddy SC, Karina R

Med J Malaysia, 2004 Aug;59(3):305-11.

PMID: 15727374 MyJurnal

A cross sectional study was conducted to assess the level of awareness and knowledge of common eye diseases (cataract, glaucoma, diabetic retinopathy and refractive errors) among 473 academic staff (non-medical faculties) of University Malaya. The awareness of cataract was in 88.2%, diabetic retinopathy in 83.5%, refractive errors in 75.3% and glaucoma in 71.5% of the study population. The knowledge about all the above common eye diseases was moderate, except presbyopia which was poor. Multivariate analysis revealed that females, older people, and those having family history of eye diseases were significantly more aware and more knowledgeable about the eye diseases. Health education about eye diseases would be beneficial to seek early treatment and prevent visual impairment in the society.

Matched MeSH terms: Eye Diseases/diagnosis*

Fulltext Candida glabrata endophthalmitis following penetrating keratoplasty in a patient with negative donor rim culture

Muzaliha MN, Adil H, Ibrahim M, Shatriah I

BMC Ophthalmol, 2010;10:18.

PMID: 20537193 DOI: 10.1186/1471-2415-10-18

Candida glabrata endophthalmitis following keratoplasty is rare and almost always associated with positive donor rim culture.

Matched MeSH terms: Eye Diseases/etiology; Eye Diseases/ultrasonography

Causes of blindness in Singapore

Lim KH

Med J Malaysia, 1975 Jun;29(4):263-9.

PMID: 1196175

Matched MeSH terms: Eye Diseases/complications

Causes of childhood blindness in Malaysia: results from a national study of blind school students

Reddy SC, Tan BC

Int Ophthalmol, 2001;24(1):53-9.

PMID: 11998890

A national study was conducted in children attending six schools for the blind in Malaysia to identify the anatomical site and underlying causes of blindness (BL) and severe visual impairment (SVI), with a view to determine the potentially preventable and treatable causes so that appropriate control measures can be implemented in the future. The standardized clinical examination of eyes was performed and the findings were recorded on the WHO Prevention of Blindness Programme eye examination record form for children with blindness and low vision. A total of 358 children aged between 7 and 17 years were examined, of whom 332 (92.7%) were blind or severely visually impaired. The results relate to these 332 children. Lens was the major anatomical site (22.3%) of visual loss followed by retina (20.8%), whole globe (17.2%), cornea (15.1%), optic nerve (8.7%) and uvea (5.1%). Glaucoma was responsible for BL/SVI in 7.2% and others in 3.6% of cases. Hereditary diseases were responsible for visual loss in 29.5%, intrauterine factors in 4.5%, perinatal factors in 9% and childhood factors in 7.8% of cases. However, the aetiology was unknown in 49.1% of cases which included congenital anomalies of the globe. Childhood cataract and corneal scarring are major treatable causes of BL/SVI that can benefit from future intervention strategies. Perinatal screening for intrauterine factors and hereditary eye diseases, and appropriate interventional therapy will help in reducing the prevalence of childhood blindness.

Matched MeSH terms: Eye Diseases/complications; Eye Diseases/prevention & control

Fulltext Causes of enucleation in West Malaysia

Chandran S

Singapore Med J, 1973 Dec;14(4):497-500.

PMID: 4788120

The primary cause of 68 enucleations in the University Hospital, Kuala Lumpur, are reviewed and compared with those from Uganda and Jerusalem. Trauma 25% especially in the 20 - 29 age group was the most important cause, followed by corneal diseases 22% seen largely over the age of 50. Malignant tumours 16% consisting nearly all of retinoblastoma and a very low incidence of malignant melanoma when compared with the Caucasians. Glaucoma 12% was mainly of the narrow angle type. Males predominate nearly all age groups with an overall ratio of 2:1 and a peak of 5:1 in trauma.

Matched MeSH terms: Eye Diseases/surgery*

Central serous retinopathy: a preliminary report of 33 cases

Eu-sen VO

Med J Malaya, 1969 Sep;24(1):18-20.

PMID: 4243836

Matched MeSH terms: Eye Diseases*

Fulltext Community eye service program: factors associated with delayed presentation to a tertiary centre post community screening

Nor Hafiza I., Lathalakshmi, T., Ab Hamid Siti-Azrin, Liza-Sharmini A.T.

Journal of Biomedical and Clinical Sciences, 2017;2(2):42-47.

MyJurnal

Early detection and prompt treatment of eye diseases can prevent visual disability. To our knowledge, there is no published data on factors associated with delayed presentation of eye diseases in Malaysia. Our objective is to determine the proportion of patients with eye disease who had a delayed presentation to an ophthalmologist after an initial screening, as well as the factors associated with delay in seeking treatment. This was a retrospective cohort study of patients with eye diseases detected during a Community Eye Survey (CES) program from September 2004 to December 2012 who were referred to the ophthalmologist in Hospital Universiti Sains Malaysia (USM). Delayed presentation of eye disease was defined as patients who came to the eye clinic more than six months after eye screening. Multiple logistic regression was used for analyses. A total of 434 patients who were referred to Hospital USM, Kubang Kerian were included in the study. Their mean (standard deviation) age was 55.65 (21.62) years. The majority of patients (76%) had delayed presentation of eye disease post screening. Type of ocular diseases was not associated with delayed presentation. The factors associated with delayed presentation were unemployment (adjusted odds ratio (OR): 2.51, 95% CI (1.36, 4.64), p

Study site: Hospital Universiti Sains Malaysia (HUSM)

Matched MeSH terms: Eye Diseases

Fulltext Comparison of open-ended and close-ended questions to determine signs and symptoms of eye problems among children

Chen AH, Bakar NA, Lam CS

J Optom, 2019 10 16;13(2):81-87.

PMID: 31629682 DOI: 10.1016/j.optom.2019.07.002

BACKGROUND: Parents play important role in providing information regarding their children's health status to healthcare providers. However, parents' ability in reporting signs and symptoms of eye problems among their children required more in-depth investigation. Our study aimed to compare the differences of parental report regarding eye problems among their children using two different question approaches.

METHODS: A total of 416 parents with children aged between two months old and 17 years old were participated in this cross-sectional survey. The responses of parents' observation on signs and symptoms of eye problems were compared between one open-ended question and ten close-ended questions. We also examined the demographic contributing factors that could influence parental responses.

RESULTS: The total count of reported signs and symptoms through open-ended and close-ended question was 164 and 529 reports, respectively. Parents reported more diverse (70% higher) categories of signs and symptoms in open-ended compared to close-ended questions. Parent's ability to report eye problems using open-ended question was associated with their gender (p<0.05), but no similar significant association was found in close-ended questions.

CONCLUSION: Parents reported more signs and symptoms of eye problems among their children through close-ended questions (regardless of gender) and more diversified categories through open-ended question in this study suggested that different communication approaches might be needed in clinical practice between those who requested specific appointment and those attending screening or routine assessment. The discrepancy might imply the importance to enhance the parent's role in preventive eye care. Effective communication between eyecare providers and parents has the potential to improve paediatric eyecare delivery.

Matched MeSH terms: Eye Diseases/diagnosis*

Complications in cataract surgery

Singh K

Med J Malaysia, 1976 Sep;31(1):38-41.

PMID: 1088175

Matched MeSH terms: Eye Diseases/etiology

Fulltext Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases

Kao YW, Hsu SK, Chen JY, Lin IL, Chen KJ, Lee PY, et al.

Int J Mol Sci, 2020 Dec 28;22(1).

PMID: 33379248 DOI: 10.3390/ijms22010212

Curcumin is one of the most valuable natural products due to its pharmacological activities. However, the low bioavailability of curcumin has long been a problem for its medicinal use. Large studies have been conducted to improve the use of curcumin; among these studies, curcumin metabolites have become a relatively new research focus over the past few years. Additionally, accumulating evidence suggests that curcumin or curcuminoid metabolites have similar or better biological activity than the precursor of curcumin. Recent studies focus on the protective role of plasma tetrahydrocurcumin (THC), a main metabolite of curcumin, against tumors and chronic inflammatory diseases. Nevertheless, studies of THC in eye diseases have not yet been conducted. Since ophthalmic conditions play a crucial role in worldwide public health, the prevention and treatment of ophthalmic diseases are of great concern. Therefore, the present study investigated the antioxidative, anti-inflammatory, antiangiogenic, and neuroprotective effects of THC on four major ocular diseases: age-related cataracts, glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR). While this study aimed to show curcumin as a promising potential solution for eye conditions and discusses the involved mechanistic pathways, further work is required for the clinical application of curcumin.

Matched MeSH terms: Eye Diseases/drug therapy*

Current progress and challenges in ocular surface reconstruction using cultivated epithelial sheet transplantation

Inatomi T, Nakamura T, Koizumi N, Sotozono C, Kinoshita S

Med J Malaysia, 2008 Jul;63 Suppl A:42.

PMID: 19024975

The cultivated epithelial transplantation is a new surgical modality for treating a variety of severe ocular surface disorders. This type of tissue-engineered epithelial sheet provides a rapid epithelial coverage on the corneal surface that reduces inflammation and postoperative complications. Although cultivated corneal epithelial transplantation is an effective surgical strategy, autologous transplantation is limited to unilateral cases. Autologous cultivated oral mucosal epithelial transplantation (COMET) enables surgeons to reconstruct the ocular surface using autologous, non-ocular surface cells, and has opened a new pathway for treating severe, bilateral ocular surface disorders.

Matched MeSH terms: Eye Diseases/surgery*; Eye Diseases/therapy

Displaying publications 1 - 20 of 87 in total