Displaying publications 1 - 20 of 274 in total

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  1. A'qilah Ahmad Dahalan, Azali Saudi, Jumat Sulaiman
    MyJurnal
    Mobile robots often have to discover a path of collision-free towards a specific goal point in their environment. We are trying to resolve the mobile robot problem iteratively by means of numerical technique. It is built on a method of potential field that count on the use of Laplace’s equation in the mobile robot’s configuration space to constrain/which reduces the generation of a potential function over regions. This paper proposed an iterative approach in solving robot path finding problem known as Accelerated Over-Relaxation (AOR). The experiment shows that these suggested approach can establish a smooth path between the starting and goal points by engaging with a finite-difference technique. The simulation results also show that a more rapidly solution with smoother path than the previous work is achieved via this numerical approach.
    Matched MeSH terms: Family Characteristics
  2. Subramanian AP, Jaganathan SK, Mandal M, Supriyanto E, Muhamad II
    World J Gastroenterol, 2016 Apr 21;22(15):3952-61.
    PMID: 27099438 DOI: 10.3748/wjg.v22.i15.3952
    AIM: To investigate the inhibitory action of diet-derived phenolic compound gallic acid (GA) against HCT-15 colon cancer cells.
    METHODS: The antiproliferative effect of GA against colon cancer cells was determined by performing thiazolyl blue tetrazolium bromide (MTT) assay. The colony forming ability of GA treated colon cancer cells was evaluated using the colony forming assay. The cell cycle changes induced by GA in HCT-15 cells were analyzed by propidium iodide staining. Levels of reactive oxygen species (ROS) and mitochondrial membrane potential of HCT-15 exposed to GA was assessed using 2',7'-dichlorfluorescein-diacetate and rhodamine-123 respectively, with the help of flow cytometry. Morphological changes caused by GA treatment in the colon cancer cells were identified by scanning electron microscope and photomicrograph examination. Apoptosis was confirmed using flow cytometric analysis of GA treated HCT-15 cells after staining with Yo-Pro-1.
    RESULTS: MTT assay results illustrated that GA has an inhibitory effect on HCT-15 cells with IC50 value of 740 μmol/L. A time-dependent inhibition of colony formation was evident with GA treatment. Cell cycle arrest was evident from the accumulation of GA treated HCT-15 cells at sub-G1 phase (0.98 ± 1.03 vs 58.01 ± 2.05) with increasing exposure time. Flow cytometric analysis of GA treated HCT-15 cells depicted early events associated with apoptosis like lipid layer breakage and fall in mitochondrial membrane potential apart from an increase in the generation of ROS which were in a time dependent manner. SEM and photomicrograph images of the GA-treated cells displayed membrane blebbing and cell shrinking characteristics of apoptosis. Further apoptosis confirmation by Yo-Pro-1 staining also showed the time-dependent increase of apoptotic cells after treatment.
    CONCLUSION: These results show that GA induced ROS dependent apoptosis and inhibited the growth of colon cancer cells.
    KEYWORDS: Apoptosis; Cell cycle; Colon cancer; Gallic acid; Lipid layer break; Reactive oxygen species
    Matched MeSH terms: Family Characteristics
  3. World AIDS Day Newsl, 1994;?(2):3.
    PMID: 12287964
    PIP: Five positive and negative experiences of families dealing with AIDS are recounted. Imrat in Malaysia is an HIV-infected son who was not rejected by his family. Prudence of Botswana is an infected widow with five children who had a less positive experience with her in-laws, while Eric of Sweden considers his friends to constitute his family. His relationships with friends have only strengthened since his HIV-positive status became known. Mary of Zimbabwe, however, was infected with HIV by her husband. She was formerly angry at him for having brought home the virus, but they have since stop quarreling and are focusing upon building a stronger relationship. Finally, the brief story of Juan in Colombia is told. Thirty-two years old, married, and with a 17-month old daughter, Juan did not tell his wife that he was actively bisexual. Once infected with HIV, Juan's wife threw him out, more because he had sex with men than because of his HIV serostatus.
    Matched MeSH terms: Family Characteristics*
  4. Karim Ghani WA, Rusli IF, Biak DR, Idris A
    Waste Manag, 2013 May;33(5):1276-81.
    PMID: 23415709 DOI: 10.1016/j.wasman.2012.09.019
    Tremendous increases in biodegradable (food waste) generation significantly impact the local authorities, who are responsible to manage, treat and dispose of this waste. The process of separation of food waste at its generation source is identified as effective means in reducing the amount food waste sent to landfill and can be reused as feedstock to downstream treatment processes namely composting or anaerobic digestion. However, these efforts will only succeed with positive attitudes and highly participations rate by the public towards the scheme. Thus, the social survey (using questionnaires) to analyse public's view and influencing factors towards participation in source separation of food waste in households based on the theory of planned behaviour technique (TPB) was performed in June and July 2011 among selected staff in Universiti Putra Malaysia, Serdang, Selangor. The survey demonstrates that the public has positive intention in participating provided the opportunities, facilities and knowledge on waste separation at source are adequately prepared by the respective local authorities. Furthermore, good moral values and situational factors such as storage convenience and collection times are also encouraged public's involvement and consequently, the participations rate. The findings from this study may provide useful indicator to the waste management authorities in Malaysia in identifying mechanisms for future development and implementation of food waste source separation activities in household programmes and communication campaign which advocate the use of these programmes.
    Matched MeSH terms: Family Characteristics
  5. Ogiri IA, Sidique SF, Talib MA, Abdul-Rahim AS, Radam A
    Waste Manag Res, 2019 Jul;37(7):755-762.
    PMID: 30967098 DOI: 10.1177/0734242X19842328
    To encourage recycling in Malaysian households, a waste separation at source programme was implemented that made it mandatory for households to sort their waste into different categories before leaving it out for collection. Penalties designed to act as a deterrent are imposed on households that fail to sort their waste appropriately. But does this deterrence motivate compliance with the programme directives? This study employs the deterrence theory to investigate if deterrence alone is sufficient to motivate households to actively participate in recycling. A total of 866 questionnaires were administered in person in households in Putrajaya and Melaka. Data were analysed using structural equation modelling. The results of the structural model reveal that just 25% of the variance in compliance is explained by the severity of the sanction, and the perceived certainty of penalty imposed. Perceived severity of sanction (β = 0.149, p = 0.012) and perceived certainty of sanction (β = 0.383, p = 0.000) were found to contribute significantly to compliance behaviour to the programme directives. However, deterrence alone cannot motivate household participation in waste separation at source because it only explains 25% of compliance behaviour. The present study provides information that could allow policymakers to understand recycling habits better and implement more effective compliance strategies.
    Matched MeSH terms: Family Characteristics*
  6. Ozawa S, Wonodi C, Babalola O, Ismail T, Bridges J
    Vaccine, 2017 11 07;35(47):6429-6437.
    PMID: 29037575 DOI: 10.1016/j.vaccine.2017.09.079
    BACKGROUND: Understanding and ranking the reasons for low vaccination uptake among parents in northern Nigeria is critical to implement effective policies to save lives and prevent illnesses. This study applies best-worst scaling (BWS) to rank various factors affecting parents' demand for routine childhood immunization.

    METHODS: We conducted a household survey in Nahuche, Zamfara State in northern Nigeria. Nearly two hundred parents with children under age five were asked about their views on 16 factors using a BWS technique. These factors focused on known attributes that influence the demand for childhood immunization, which were identified from a literature review and reviewed by a local advisory board. The survey systematically presented parents with subsets of six factors and asked them to choose which they think are the most and least important in decisions to vaccinate children. We used a sequential best-worst analysis with conditional logistic regression to rank factors.

    RESULTS: The perception that vaccinating a child makes one a good parent was the most important motivation for parents in northern Nigeria to vaccinate children. Statements related to trust and social norms were ranked higher in importance compared to those that highlighted perceived benefits and risks, healthcare service, vaccine information, or opportunity costs. Fathers ranked trust in the media and views of their leaders to be of greatest importance, whereas mothers placed greater importance on social perceptions and norms. Parents of children without routine immunization ranked their trust in local leaders about vaccines higher in considerations, and the media's views lower, compared to parents with children who received routine immunization.

    CONCLUSIONS: Framing immunization messages in the context of good parenting and hearing these messages from trusted information sources may motivate parental uptake of childhood vaccines. These results are useful to policymakers to prioritize resources in order to increase awareness and demand for childhood immunization.

    Matched MeSH terms: Family Characteristics
  7. NURUL NADHILAH FEIZAL, SHAHNAZ ISMAIL, WAN ZURIATI WAN ZAKARI, NADIA MOHD NAWI
    MyJurnal
    The advancement of technology in digital revolution such as Internet of Things has gained attention in all over the world. This myriad of technology innovations affects all aspects of the human lives today. The generation who has grown up during this era, knownastheiGens,mostlyreliesonthetechnologyineveryaspectoftheirlives,including education. Thus, technology also gives profound impact in educational transformation nowadays to convey innovative education. However, lack of innovation in education becomes a challenge to meet this demand. Therefore, this study was carried out with the aim to discover factors which may affect academic performance of the iGen students in the university. A total of 250 self-administered questionnaires were distributed to the accountingstudentsatUMTwitharesponserateof93.6%(234).Usingmultipleregression analysis, the findings showed that parental involvement and student’s attitude contribute more towards academic performance of iGen students rather than the technology itself. This finding showed that human factor such as support fromtheir parents and individual factor are vital towards their academic performance regardless of from technology savvy generation or not.
    Matched MeSH terms: Family Characteristics
  8. LEONG JIA Q, WAN ZALIHA WAN SEMBOK
    MyJurnal
    Pineapple is one of the most important commercial fruit crops served in fresh-cut form which is convenientfor the consumers. However, fresh-cut pineapple induces the activity of phenolic compounds which triggers the generation of brown or dark pigments. Browning incidence (BI) directly influences the fruit’s acceptability and marketability. Therefore, different exposure times (5mins, 10mins, 15mins and 20mins)and typesof LED lights (white, red and blue) were applied on fresh-cut pineapple stored at 5oC storage for twelve days to reduce BI. A significant interaction between the two factors was recorded in lightness coefficient, chroma, total phenolic and ascorbic acid (AA)contents. Regardless of exposure times, all types of LED lights, mainly the blue light, succeeded in delaying BI in fresh-cut pineapple. In conclusion, blue light had a tendency todelay BI andmaintaintheother postharvest quality attributes of fresh-cut pineapple.
    Matched MeSH terms: Family Characteristics
  9. NUR SYUHADA IBRAHIM, ZIKRI MUHAMMAD, JUMADIL SAPUTRA
    MyJurnal
    Industrial development plays the most important role inthe degradationof the global environment. In line with this issue, most universities in the world have introduced environmentalmanagement to increase awarenessamong young generation towards the environment. Therefore, this study is employed to examine the influences of hygiene practices, awareness and involvement levels towards environmentalhygiene among UMT students. The design of this study is quantitative using cross-sectionaldata collectedfrom students at residential colleges in Universiti Malaysia Terengganu. A total of 120 respondents participatedbut only data from 100 students could be used for further analysis after the datascreening process. The result of this study showed that the level of awareness of UMT students on environmental issues could be categorized as moderate. Besides that, this study found that the level of awareness had significant positive influences on environmentalhygiene. Meanwhile, hygiene practices and the level of involvement did not have significant influences on environmentalhygiene. In addition, using the findings of this study, we suggest that the stakeholders of UMT increase the hygiene practice and involvement among young generation to increase the level of awareness regarding environmental hygiene.
    Matched MeSH terms: Family Characteristics
  10. Ghaffari Khaligh N, Mihankhah T, Titinchi S, Shahnavaz Z, Rafie Johan M
    Turk J Chem, 2020;44(4):1100-1109.
    PMID: 33488215 DOI: 10.3906/kim-2005-6
    This work introduces a new additive named 4,4'-trimethylenedipiperidine for the practical and ecofriendly preparation of ethyl 5-amino-7-(4-phenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate derivatives. This chemical is commercially available and easy to handle. It also possesses a low melting point and a broad liquid range temperature, high thermal stability, and good solubility in water. Based on green chemistry principles, the reaction was performed in a) a mixture of green solvents i.e. water and ethanol (1:1 v/v) at reflux temperature, and b) the additive was liquefied at 65 °C and the reaction was conducted in the liquid state of the additive. High yields of the desired triazolo-pyrimidines were obtained under both aforementioned conditions. Our results demonstrated that this additive, containing 2 Lewis base sites and able to act as an acceptor-donor hydrogen bonding group, is a novel and efficient alternative to piperidine, owing to its unique properties such as its reduced toxicity, nonflammable nature, nonvolatile state, broad liquid range temperature, high thermal stability, and ability to be safely handled. Furthermore, this additive could be completely recovered and exhibited high recyclability without any change in its chemical structure and no significant reduction in its activity. The current methodology has several advantages: (a) it avoids the use of hazardous materials, as well as toxic, volatile, and flammable solvents, (b) it does not entail tedious processes, harsh conditions, and the multistep preparation of catalysts, (c) it uses a metal-free and noncorrosive catalyst, and (d) reduces the generation of hazardous waste and simple work-up processes. The most important result of this study is that 4,4'-trimethylenedipiperidine can be a promising alternative for toxic, volatile, and flammable base reagents in organic synthesis owing to its unique properties.
    Matched MeSH terms: Family Characteristics
  11. Zaharani L, Ghaffari Khaligh N, Shahnavaz Z, Rafie Johan M
    Turk J Chem, 2020;44(3):535-542.
    PMID: 33488175 DOI: 10.3906/kim-2002-26
    In the current protocol, the arene diazonium saccharin derivatives were initially produced from various substituted aromatic amines; subsequently, these intermediates were treated with a greener organic iodide for the preparation of the aryl iodide. We tried to choose low-cost, commercially available, biodegradable, recoverable, ecofriendly, and safe reagents and solvents. The arene diazonium saccharin intermediates could be stored in the liquid phase into a refrigerator for a long time with no significant loss activity. The outstanding merits of the current protocol (a) included the partial recovering of saccharin and tetraethylammonium salt, (b) reduce the use of solvents and the reaction steps due to eliminating separation and purification of intermediates, (c) good yield of the sterically hindered substrates, and (d) avoid the generation of heavy metal or corrosive waste.
    Matched MeSH terms: Family Characteristics
  12. Mahmud F, Lee PC, Abdul Wahab H, Mustaffa KMF, Leow CH, Azhar R, et al.
    Trop Biomed, 2020 Sep 01;37(3):822-841.
    PMID: 33612795 DOI: 10.47665/tb.37.3.822
    Malaria is one of the most dangerous infectious diseases due to its high infection and mortality rates, especially in the tropical belt. Plasmodium falciparum (P. falciparum), the most virulent malaria parasite in humans, was recently reported to develop resistance against the final efficient antimalarial drug, artemisinin. Little is known about the resistance mechanisms, which further complicates the problem as a proper counteraction is unable to be taken. Hence, the understanding of drug mode of action and its molecular target is valuable knowledge that needs to be considered to develop the next generation of antimalarial drugs. P. falciparum protein kinase (Pf PK) is an attractive target for antimalarial chemotherapy due to its vital roles in all P. falciparum life stages. Moreover, overall structural differences and the presence of unique Pf PKs that are absent in human kinome, suggesting specific inhibition of Pf PK without affecting human cells is achievable. To date, at least 86 eukaryotic protein kinases have been identified in P. falciparum kinome, by which less than 40 were validated as potential targets at the erythrocytes stage. In this review, recent progress of the furthest validated Pf PKs; Pf Nek-1, Pf CDPK1, Pf CDPK4, Pf PKG, and Pf CLK-3 will be briefly discussed.
    Matched MeSH terms: Family Characteristics
  13. Thatrimontrichai A, Premprat N, Janjindamai W, Dissaneevate S, Maneenil G
    Trop Biomed, 2020 Sep 01;37(3):663-670.
    PMID: 33612780 DOI: 10.47665/tb.37.3.663
    Third-generation cephalosporin resistant Enterobacteriaceae (TCRE) is a global concern especially in neonatal sepsis. We performed a secondary data analysis in a Thai neonatal intensive care unit to identify the risk factors for acquisition of TCRE sepsis and mortality of Enterobacteriaceae sepsis between 1991 and 2017. Multivariate logistic and Cox proportional regression were used for analysis. Numbers of neonates with TCRE and nonTCRE sepsis were 100 and 41 patients, respectively. Medians (interquartile ranges) of gestational age, birthweight, onset of sepsis and total hospital stay of neonates with Enterobacteriaceae sepsis were 32 (28, 38) weeks, 1670 (1025, 2750) grams, 11 (6, 25) days and 41 (22, 74) days, respectively. Univariate and multivariate analysis, neonates with TCRE sepsis were more likely to have birth asphyxia (adjusted odds ratio [aOR] = 2.6; 95% confidence interval [CI] 1.1-6.0; p = 0.02) and history of aminoglycoside exposure (aOR = 2.9; 95% CI 1.3- 6.7; p = 0.01). In-hospital case fatality rate from Enterobacteriaceae sepsis was 26% (36/141). In Cox regression, neonates with TCRE sepsis was not an independent risk of non-survivors, but septic shock (adjusted hazard ratio = 9.9; 95% CI 5.0-19.7, p < 0.001) increased 30-day mortality in the final model. Asphyxia and previous aminoglycoside consumption were risks of acquisition for neonatal TCRE sepsis while the burden was not a significant difference. Infection prevention and control must be strictly implemented in high multidrug-resistant area.
    Matched MeSH terms: Family Characteristics
  14. Komatsu N, Lio H, Ooi HK
    Trop Biomed, 2021 Jun 01;38(2):48-52.
    PMID: 33973572 DOI: 10.47665/tb.38.2.036
    We described a new species of cockroach, Periplaneta gajajimana sp. nov., which was collected in Gajajima, Kagoshima-gun Toshimamura, Kagoshima Prefecture, Japan, on November 2012. The new species is characterized by its reddish brown to blackish brown body, smooth surface pronotum, well developed compound eyes, dark brown head apex, dark reddish brown front face and small white ocelli connected to the antennal sockets. In male, the tegmen tip reach the abdomen end or are slightly shorter, while in the female, it does not reach the abdominal end and exposes the abdomen beyond the 7th abdominal plate. We confirmed the validity of this new species by breeding the specimens in our laboratory to demonstrate that the features of the progeny were maintained for several generations. For comparison and easy identification of this new species, the key to species identification of the genus Periplaneta that had been reported in Japan to date are also presented.
    Matched MeSH terms: Family Characteristics
  15. Khan M, Mahmood HZ, Noureen S, Muhmood K, Husnain MIU, Hameed Khaliq I
    Trop Biomed, 2019 Sep 01;36(3):664-676.
    PMID: 33597488
    The extent of the economic burden of malaria and its imposed mechanisms are both relevant to public policy. This paper investigates the economic burden of malaria and household behaviour in relation to the treatment and prevention of the illness in Pakistan. In this regard, data were collected from a randomly selected sample of 360 households using structured questionnaires. The survey results indicate that 23.4% of household members contracted malaria during the three-month reference period. The average per person cost of malaria is estimated at 3116 Pakistani rupees (PKR) (USD 32). The estimated cost of the illness was found to be equivalent to, on average, 6.7% of monthly household income. Although high-income households face a higher financial burden due to better preventive and mitigation measures, the negative consequences hit low-income households harder due to liquidity constraints and poor access to effective treatment. We recommend that malaria control policies be integrated into development and poverty reduction programs.
    Matched MeSH terms: Family Characteristics
  16. Sinniah B, Sinniah D, Rajeswari B
    Trop Geogr Med, 1983 Dec;35(4):337-42.
    PMID: 6670116
    A survey of 4.112 primary school children living in and around Kuala Lumpur, Malaysia, revealed that 12.9% of the children were infested with Pediculus humanus capitis. Indians (28.3%) and Malays (18.9%) have a higher prevalence than Chinese (4.6%). The higher prevalence among Indians and Malays correlates well with their lower socio-economic status in the community; long hair also contributes to the higher rates of pediculosis among them. The prevalence rate was found to be related to socio-economic status, length of hair, family size, age, crowding and personal hygiene. Treatment with 0.2% and 0.5% malathion in coconut oil gave cure rates of 93% and 100%. Treatment with gammexane and actellic at 0.5% concentration gave a cure rate of 100% against adults and nymphs of Pediculus humanus capitis.
    Matched MeSH terms: Family Characteristics
  17. Chen ST
    Trop Geogr Med, 1975 Mar;27(1):103-8.
    PMID: 806152
    Pneumonia and diarrhoeas are an important cause of toddler mortality and morbidity in developing countries. Of the 147 children admitted to the University Hospital at Kuala Lumpur in 1971 for pneumonia and diarrhoeas 50 (34%) were found to be suffering from protein-calorie malnutrition of varying degrees of severity. The malnourished children tended to come from poorer homes, and to have a larger number of siblings born in rapid succession when compared with normal weight children. Anemia was more common among the malnourished children. The interaction of infection and malnutrition and the social implications of these diseases are important. It is vital that hospitals in developing countries promote health in addition to their traditional curative role.
    Matched MeSH terms: Family Characteristics
  18. NWANESI PETER KARUBI, ELAINE CHAI YEE NING
    MyJurnal
    This article examines the impact of gender socialization in Malaysian families, especially on daughters regarding their perception towards work inside and outside the home. Hence, this study utilized in-depth interview as part of the qualitative methods to obtain quality data needed. The study establishes, that patriarchy environment, especially one with the classic model of ‘breadwinner father, housewife mother’ creates a pressure on women to bear more household responsibility. Thus, the dominant gender ideologies are entangled with ‘motherhood mandate’ and ‘superior feminine virtue’ that is associated with the reason women left the labour force. It was equally necessary to point out here that other agents of socialization such as media, peers and education played its part as well and influenced the respondent’s conformity to patriarchal values.
    Matched MeSH terms: Family Characteristics
  19. NURUL NADZATUL FARAH MOHD KHAIRI
    MyJurnal
    A livelihood is a means of making a living, securing necessities of life such as water, shelter medicine and clothing. For communities dependent on forest resources for livelihoods, sustainability of forests are important. In Kampung Tambirat this study aims to find the income generated from forest resources particularly Nypah palm forests, the measures of conservation, challenges and type of assistance required so that the villagers engagement in the activities will flourish in the future and benefit the younger generations. It is found that there are no conservation measures for Nypah forests and seasonal floods further increases the difficulty for the villagers to sustain their livelihood activities.
    Matched MeSH terms: Family Characteristics
  20. Tsubouchi Y
    Tonan Ajia Kenkyu, 1992 Sep;30(2):192-212.
    PMID: 12157850
    "The Malay village of Galok in Kelantan was revisited [in]...1991 to investigate the changes in the population and households in the 20 years since the first intensive community study was conducted there in 1970/71. Major economic activities in 1970/71 were paddy cultivation in rain-fed fields, small scale rubber tapping, and newly introduced tobacco cultivation. The village's population increased from 690 in 1971 to 1,100 in 1991, and the number of households from 145 to 211. Despite the increase in population and households, the households cultivating paddy decreased from 71 to 36, those tapping rubber from 94 to 53, and those growing tobacco from 124 to 40, while regular employment, irregular wage labor in the surrounding areas, and temporary migratory work in Singapore increased remarkably. Many people moved out of the village and many others moved in. Though the former exceed the latter in number, the village population is still increasing owing to the high fertility...." (SUMMARY IN ENG)
    Matched MeSH terms: Family Characteristics*
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