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Fulltext A Review on the Potential Bioactive Components in Fruits and Vegetable Wastes as Value-Added Products in the Food Industry

'Aqilah NMN, Rovina K, Felicia WXL, Vonnie JM

Molecules, 2023 Mar 14;28(6).
PMID: 36985603 DOI: 10.3390/molecules28062631

The food production industry is a significant contributor to the generation of millions of tonnes of waste every day. With the increasing public concern about waste production, utilizing the waste generated from popular fruits and vegetables, which are rich in high-added-value compounds, has become a focal point. By efficiently utilizing food waste, such as waste from the fruit and vegetable industries, we can adopt a sustainable consumption and production pattern that aligns with the Sustainable Development Goals (SDGs). This paper provides an overview of the high-added-value compounds derived from fruit and vegetable waste and their sources. The inclusion of bioactive compounds with antioxidant, antimicrobial, and antibrowning properties can enhance the quality of materials due to the high phenolic content present in them. Waste materials such as peels, seeds, kernels, and pomace are also actively employed as adsorbents, natural colorants, indicators, and enzymes in the food industry. Therefore, this article compiles all consumer-applicable uses of fruit and vegetable waste into a single document.

Matched MeSH terms: Food Industry
Fulltext LACTIC ACID BACTERIA ISOLATED FROM LOCALLY PRODUCED VINEGARS AND THEIR ANTIBACTERIAL ACTIVITY AGAINST FOODBORNE BACTERIA

AGNES LEE CHIU NEE, MOHD NIZAM LANI, ROZILA ALIAS, ZAITON HASSAN

UMT Journal of Undergraduate Research, 2019;1(2):1-7.
MyJurnal

Vinegars are most widely used as preservatives in food industry. Vinegars are known for their health benefits; however, the roles of vinegar-associated microflora in locally produced vinegars are not well established. The objectives of this study are to isolate and identify the lactic acid bacteria (LAB) from black rice vinegar and coconut vinegar, measure their pH and titratable acidity, and determine their antibacterial activity. LAB was isolated using cultural method. Phenotypic characterization of LAB was carried out using Gram-staining, oxidase test, catalase test and API 50 CHL Kit. Results from API 50 CHL Kit confirmed that BRV03M strain from black rice vinegar and CV03M strain from coconut vinegar were Lactobacillus paracaseissp. paracasei. The identified bacteria in both samples were consistent as L. paracaseiusing 16S rDNAgene sequences with 93% and 99% similarity, respectively. The pH and titratable acidity percentage of both vinegars were also determined. The stability of Cell Free Supernatant-Lactic Acid Bacteria (CFS-LAB) strains within 14 days on their inhibition against selected pathogenic bacteria was determined using agar well diffusion method. The CFS-LAB strain isolated from black rice vinegar (BRV03M) was more stable within 14 days than coconut vinegar in inhibiting tested bacteria, suggesting this strain has great potential as natural antibacterial agents.

Matched MeSH terms: Food Industry
Fulltext Regulatory guidelines for biosimilars in Malaysia

Abas A

Biologicals, 2011 Sep;39(5):339-42.
PMID: 21784655 DOI: 10.1016/j.biologicals.2011.06.009

The biosimilars sector continues to attract huge interest and controversy. Biosimilars are new biopharmaceuticals that are "similar" but not identical to the innovator product. Characteristics of biopharmaceuticals are closely related to the manufacturing process, which implies that the products cannot be exactly duplicated. Minuscule differences in the product's structure and manufacturing process can result in different clinical outcome. This raises concerns over the safety, efficacy and even pharmacovigilance of biosimilars. Thus, biosimilars are unique - they are not a true chemical generic and are regulated via a distinct regulatory framework. This report discusses the features of Malaysian regulatory oversight of biosimilars and experience acquired in the evaluation of some products from various countries. Ensuring regulatory position adequately reflects scientific advancement, expertise/resources is key. The regulatory situation is an evolving process. Various guidance documents are being prepared with the aim of developing a uniform global framework towards assuring the dual goal of lower costs and patient safety while expediting the availability of important biosimilar products.

Matched MeSH terms: Drug Industry/legislation & jurisprudence*; Drug Industry/standards*
Fulltext Fatal occupational injuries among non-governmental employees in Malaysia

Abas AB, Mohd Said DA, Aziz Mohammed MA, Sathiakumar N

Am. J. Ind. Med., 2013 Jan;56(1):65-76.
PMID: 22544443 DOI: 10.1002/ajim.22056

BACKGROUND: In Malaysia, surveillance of fatal occupational injuries is fragmented. We therefore analyzed an alternative data source from Malaysia's Social Security organization, the Pertubuhan Keselamatan Sosial (PERKESO).
METHODS: We conducted a secondary data analysis of the PERKESO database comprised of 7 million employees from 2002 to 2006.
RESULTS: Overall, the average annual incidence was 9.2 fatal occupational injuries per 100,000 workers. During the 5-year period, there was a decrease in the absolute number of fatal injuries by 16% and the incidence by 34%. The transportation sector reported the highest incidence of fatal injuries (35.1/100,000), followed by agriculture (30.5/100,000) and construction (19.3/100,000) sectors. Persons of Indian ethnicity were more likely to sustain fatal injuries compared to other ethnic groups.
CONCLUSIONS: Government and industry should develop rigorous strategies to detect hazards in the workplace, especially in sectors that continuously record high injury rates. Targeted interventions emphasizing worker empowerment coupled with systematic monitoring and evaluation is critical to ensure success in prevention and control measures.

Matched MeSH terms: Construction Industry/statistics & numerical data*
Fulltext Non-fatal occupational injuries among non-governmental employees in Malaysia

Abas AB, Said AR, Mohammed MA, Sathiakumar N

Int J Occup Environ Health, 2011 Jan-Mar;17(1):38-48.
PMID: 21344818

We analyzed data on non-fatal occupational injuries reported to Malaysia's social security organization from 2002 to 2006. There was a decrease in both the absolute number and the incidence rates of these injuries over time. About 40% of cases occurred in the manufacturing sector followed by the service (17%) and trading (17%) sectors. The agriculture sector reported the highest incidence rate (24.1/1,000), followed by the manufacturing sector subcategories of wood-product manufacturing (22.1/1,000) and non-metallic industries (20.8/1,000). Men age 40 to 59 and persons of Indian ethnicity had a greater tendency to sustain injuries. Government and non-governmental organizations should strive to develop strategies to reduce the occupational injuries targeting vulnerable groups. Enforcement of safety measures will further play an important role to ensure that both employees and employers take special precautions to address workplace hazards.

Matched MeSH terms: Industry
An assessment of the concentrations of particulate polycyclic aromatic hydrocarbons (PAHs) in the aftermath of a chemical store fire incident

Abas MR, Omar NY, Maah MJ

J Environ Sci (China), 2004;16(5):751-4.
PMID: 15559805

PM10 airborne particles and soot deposit collected after a fire incident at a chemical store were analyzed in order to determine the concentrations of polycyclic aromatic hydrocarbons (PAHs). The samples were extracted with 1:1 hexane-dichloromethane by ultrasonic agitation. The extracts were then subjected to gas chromatography-mass spectrometric (GC-MS) analysis. The total PAHs concentrations in airborne particles and soot deposit were found to be 3.27 +/- 1.55 ng/m3 and 12.81 +/- 24.37 microg/g, respectively. Based on the molecular distributions of PAHs and the interpretation of their diagnostic ratios such as PHEN/(PHEN + ANTH), FLT/(FLT + PYR) and BeP/(BeP + BaP), PAHs in both airborne particles and soot deposit may be inferred to be from the same source. The difference in the value of IP/(IP + BgP) for these samples indicated that benzo[g, h, i] perylene and coronene tend to be attached to finer particles and reside in the air for longer periods. Comparison between the molecular distributions of PAHs and their diagnostic ratios observed in the current study with those reported for urban atmospheric and roadside soil particles revealed that they are of different sources.

Matched MeSH terms: Chemical Industry*
Antibiotic susceptibility and molecular characterization of Salmonella enterica serovar Paratyphi B isolated from vegetables and processing environment in Malaysia

Abatcha MG, Effarizah ME, Rusul G

Int J Food Microbiol, 2019 Feb 02;290:180-183.
PMID: 30342248 DOI: 10.1016/j.ijfoodmicro.2018.09.021

Salmonella enterica serovar Paratyphi B (S. Paratyphi B) is a major foodborne pathogen distributed all over the world. However, little is known about the antibiotic resistance, genetic relatedness and virulence profile of S. Paratyphi B isolated from leafy vegetables and the processing environment in Malaysia. In this study, 6 S. Paratyphi B isolates were recovered from different vegetables and drain water of processing areas obtained from fresh food markets in Malaysia. The isolates were characterized by antibiogram, Pulsed-field gel electrophoresis (PFGE) and virulence genes. Antibiotic susceptibility test showed that 3 of the isolates were resistant to the antibiotics. These include S. Paratyphi B SP251 isolate, which was resistant to chloramphenicol, ampicillin, sulfonamides and streptomycin; Isolate SP246 which was resistant to chloramphenicol, sulfonamides and streptomycin and Isolate SP235 showing resistance to nalidixic acid only. PFGE subtyped the 6 S. Paratyphi B isolates into 6 distinct XbaI-pulsotypes, with a wide range of genetic similarity (0.55 to 0.9). The isolates from different sources and fresh food markets location were genetically diverse. Thirteen (tolC, orgA, spaN, prgH, sipB, invA, pefA, sofB, msgA, cdtB, pagC, spiA and spvB) out of the 17 virulence genes tested were found in all of the S. Paratyphi B isolates. Another gene (lpfC), was found only in one isolate (SP051). None of the isolates possessed sifA, sitC and ironN genes. In summary, this study provides unique information on antibiotic resistance, genetic relatedness, and virulotyping of S. Paratyphi B isolated from leafy vegetables and processing environment.

Matched MeSH terms: Food-Processing Industry
Fulltext In vitro assessment of Pediococcus acidilactici Kp10 for its potential use in the food industry

Abbasiliasi S, Tan JS, Bashokouh F, Ibrahim TAT, Mustafa S, Vakhshiteh F, et al.

BMC Microbiol, 2017 May 23;17(1):121.
PMID: 28535747 DOI: 10.1186/s12866-017-1000-z

BACKGROUND: Selection of a microbial strain for the incorporation into food products requires in vitro and in vivo evaluations. A bacteriocin-producing lactic acid bacterium (LAB), Pediococcus acidilactici Kp10, isolated from a traditional dried curd was assessed in vitro for its beneficial properties as a potential probiotic and starter culture. The inhibitory spectra of the bacterial strain against different gram-positive and gram-negative bacteria, its cell surface hydrophobicity and resistance to phenol, its haemolytic, amylolytic and proteolytic activities, ability to produce acid and coagulate milk together with its enzymatic characteristics and adhesion property were all evaluated in vitro.
RESULTS: P. acidilactici Kp10 was moderately tolerant to phenol and adhere to mammalian epithelial cells (Vero cells and ileal mucosal epithelium). The bacterium also exhibited antimicrobial activity against several gram-positive and gram-negative food-spoilage and food-borne pathogens such as Listeria monocytgenes ATCC 15313, Salmonella enterica ATCC 13311, Shigella sonnei ATCC 9290, Klebsiella oxytoca ATCC 13182, Enterobacter cloaca ATCC 35030 and Streptococcus pyogenes ATCC 12378. The absence of haemolytic activity and proteinase (trypsin) and the presence of a strong peptidase (leucine-arylamidase) and esterase-lipase (C4 and C8) were observed in this LAB strain. P. acidilactici Kp10 also produced acid, coagulated milk and has demonstrated proteolytic and amylolactic activities.
CONCLUSION: The properties exhibited by P. acidilactici Kp10 suggested its potential application as probiotic and starter culture in the food industry.

Matched MeSH terms: Food Industry*
Fulltext WERA: an observational tool develop to investigate the physical risk factor associated with WMSDs

Abd Rahman MN, Abdul Rani MR, Rohani JM

J Hum Ergol (Tokyo), 2011 Dec;40(1-2):19-36.
PMID: 25665205 DOI: 10.11183/jhe.40.19

This paper describes the development of the Workplace Ergonomic Risk Assessment (WERA) for investigating the physical risk factor associated with work-related musculoskeletal disorders (WMSDs). The initial development of WERA tool involved the following procedures: (1) first stage, development of WERA prototype from literature review, (2) second stage, evaluation of the psychometric properties including (a) validity trials and (b) reliability and usability trials. In the validity trials, the relationship of the individual WERA body part scores to the development of pain or discomfort is statistically significant for the wrist, shoulder and back regions. It shows that the WERA assessment provided a good indication of work-related musculoskeletal disorders which might be reported as pain, ache or discomfort in the relevant body regions. In the reliability trials, the results of inter-observer reliability shows that moderate agreement among the observers while from the feedback questionnaire survey about the usability of WERA tool, all participants including expert and management teams agreed that the prototype of WERA tool was easy and quick to use, applicable to workplace assessment for the wide range of job/task and valuable at work. It was confirmed that there was no need of training required to do WERA assessment. Therefore, the WERA assessment has been designed for easy and quick use, and for those who are trained to use it do not need previous skills in observation techniques although this would be an advantage. As WERA is a pen and paper technique that can be used without any special equipment, WERA assessment can be done in any space of workplaces without disruption to the task that have been observed.

Matched MeSH terms: Construction Industry
Fulltext A Novel Eddy Current Testing Error Compensation Technique Based on Mamdani-Type Fuzzy Coupled Differential and Absolute Probes

Abdalla AN, Ali K, Paw JKS, Rifai D, Faraj MA

Sensors (Basel), 2018 Jun 30;18(7).
PMID: 29966367 DOI: 10.3390/s18072108

Eddy current testing (ECT) is an accurate, widely used and well-understood inspection technique, particularly in the aircraft and nuclear industries. The coating thickness or lift-off will influence the measurement of defect depth on pipes or plates. It will be an uncertain decision condition whether the defects on a workpiece are cracks or scratches. This problem can lead to the occurrence of pipe leakages, besides causing the degradation of a company’s productivity and most importantly risking the safety of workers. In this paper, a novel eddy current testing error compensation technique based on Mamdani-type fuzzy coupled differential and absolute probes was proposed. The general descriptions of the proposed ECT technique include details of the system design, intelligent fuzzy logic design and Simulink block development design. The detailed description of the proposed probe selection, design and instrumentation of the error compensation of eddy current testing (ECECT) along with the absolute probe and differential probe relevant to the present research work are presented. The ECECT simulation and hardware design are proposed, using the fuzzy logic technique for the development of the new methodology. The depths of the defect coefficients of the probe’s lift-off caused by the coating thickness were measured by using a designed setup. In this result, the ECECT gives an optimum correction for the lift-off, in which the reduction of error is only within 0.1% of its all-out value. Finally, the ECECT is used to measure lift-off in a range of approximately 1 mm to 5 mm, and the performance of the proposed method in non-linear cracks is assessed.

Matched MeSH terms: Industry
Evaluation of processed green and ripe mango peel and pulp flours (Mangifera indica var. Chokanan) in terms of chemical composition, antioxidant compounds and functional properties

Abdul Aziz NA, Wong LM, Bhat R, Cheng LH

J Sci Food Agric, 2012 Feb;92(3):557-63.
PMID: 25363645 DOI: 10.1002/jsfa.4606

Mango is a highly perishable seasonal fruit and large quantities are wasted during the peak season as a result of poor postharvest handling procedures. Processing surplus mango fruits into flour to be used as a functional ingredient appears to be a good preservation method to ensure its extended consumption.

Matched MeSH terms: Food-Processing Industry/economics
Transesterification reaction for synthesis of palm-based ethylhexyl ester and formulation as base oil for synthetic drilling fluid

Abdul Habib NS, Yunus R, Rashid U, Taufiq-Yap YH, Abidin ZZ, Syam AM, et al.

J Oleo Sci, 2014;63(5):497-506.
PMID: 24717547

The use of vegetable oil-based ester as a base fluid in synthetic drilling fluid has become a trend in drilling operations due to its environmental advantages. The transesterification reaction of palm oil methyl ester (POME) with 2-ethylhexanol (2EH) produced 98% of palm oil-based ethylhexyl ester in less than 30 minutes. Since the transesterification reaction of POME with 2EH is a reversible reaction, its kinetics was studied in the presence of excess EH and under vacuum. The POME-to-EH molar ratio and vacuum pressure were held constant at 1:2 and 1.5 mbar respectively and the effects of temperature (70 to 110°C) were investigated. Using excess of EH and continual withdrawal of methanol via vacuum promoted the reaction to complete in less than 10 minutes. The rate constant of the reaction (k) obtained from the kinetics study was in the range of 0.44 to 0.66 s⁻¹ and the activation energy was 15.6 kJ.mol⁻¹. The preliminary investigations on the lubrication properties of drilling mud formulated with palm oil-based 2EH ester indicated that the base oil has a great potential to substitute the synthetic ester-based oil for drilling fluid. Its high kinematic viscosity provides better lubrication to the drilling fluid compared to other ester-based oils. The pour point (-15°C) and flash point (204°C) values are superior for the drilling fluid formulation. The plastic viscosity, HPHT filtrate loss and emulsion stability of the drilling fluid had given acceptable values, while gel strength and yield point could be improved by blending it with proper additives.

Matched MeSH terms: Industry*
Fulltext Identification of Noise Levels for Skill Training Activities, Equipment, Machines and Power Tools at TVET Institutes in Malaysia

Abdul Rahim KA, Jewaratnam J, Che Hassan CR

Int J Environ Res Public Health, 2022 Nov 27;19(23).
PMID: 36497858 DOI: 10.3390/ijerph192315783

The use of various machines, equipment and power tools at TVET Institute causes the institute's environment to be exposed to noise hazards that are similar to the industry. However, not much data has been published regarding noise exposure at TVET institutes. This study was carried out to document the noise exposure of work activities training in public TVET institutes in Malaysia that implement skill training programs in metal fabrication, furniture manufacturing and automotive maintenance. The identification of excessive noise, task-based noise exposure monitoring and source measurement was conducted. The noise contribution from each work activity to the daily A-weighted noise exposure level and sound pressure level emitted by machines and equipment was documented. The findings of this study recorded 20 activities with task-based noise contribution to the daily A-weighted noise exposure level between 75.3 dB and 95 dB. Based on the findings, the training environment at the TVET institutes has a risk of operating with excessive noise. The documented data can be used in planning the implementation of suitable noise control measures in TVET institutes.

Matched MeSH terms: Industry
Fulltext Analysis of turnover intention among manufacturing technicians in electronic industry

Abdul Rashid Ismail, Wan Normeza Wan Zakaria

Journal of Advanced Research Design, 2017;37(1):1-8.
MyJurnal

This study aims to examine the influences of the plan to further study, career growth
and discriminatory treatment on turnover intention among technicians in electronic
industry in Malaysia. The objectives are: (i) To identify the relationship between the
plan to further study and turnover intention among factory technicians, (ii) To identify
the relationship between career growth and turnover intention among factory
technicians, and (iii)To identify the relationship between discriminatory treatment
factors and turnover intention among factory technicians. The population involved in
this study were the manufacturing technicians at an electronic factory. Survey
questionnaires were used to collect data. A total of 110 questionnaires were analyzed.
Pearson correlation coefficient and regression analysis were used to measure the
degree of relationship between variables. The findings showed that all independent
variables; plan to further study, career growth and discriminatory treatment, were
positive moderately correlated with turnover intention.

Matched MeSH terms: Industry
Fulltext The relationship between emotional dimensions of sustainable development among the employees of readymade garments (RMG)

Abdul Rashid, Abdullah, Ariful, Islam

The Pertanika Journal of Scholarly Research Reviews, 2019;5(1):20-26.
MyJurnal

Readymade garments (RMG) industry of Bangladesh are lesser revealed to sustainable outlines that originating avoidance related with standard health and safety provisions, labor rights, women safety, child labor, pollution, waste disposal and ground water depletion. Recently there are also several safety hazards by way of fire incidents and building collapses which caused death and injury of thousand or garment workers at Bangladesh. Actually a suitable sustainable development scheme for this industry includes the insights of proper employee involvement based upon what is known (knowledge) and done (behavior). So the study aims to investigate the relationship between knowledge and behavior which reflects the complication between what is in fact known and what is done in case of sustainable issues. The study has used both questionnaire survey and interview procedures on 10 BGMEA registered factories of Chittagong to recognize the connection between knowledge and behavior. The target populace of the study has been limited only to the white collar employees. However, the study identified that employee knowledge and behavior of sustainable development contains a moderate, positive relationship (r=.315, n=150, p

Matched MeSH terms: Industry
Prevalence and type of injuries and its associated factors among small scale fishermen in Northern Kedah

Abdul Rashid, K., Narayan, K.A., Azizah, A.M.

Journal of Occupational Safety and Health, 2007;4(1):5-9.
MyJurnal

Fishing industry in Malaysia is dominated by small scale fishing, scattered along the coast of the country. The risk associated with fishing industry is well known but few studies have been done among those in the small scale fishing community. Fishermen not only have to cope with the uncertainty of nature but also the physical demands of the occupation. The objective of the study was to determine the injuries and its associated factors related to the small scale fishing industry. The study was conducted in a fishing village in northern Malaysia, which was hit by tsunami. Most of the boats and fishing gear were donated by many relief agencies. A descriptive cross sectional study was conducted using a standardized questionnaire. 50 (83.3%) of the 60 fishermen had consented for the study. All the fishermen were Malays males. 46% (n=23) of the fishermen reported to having sustained injuries. Most of the injuries occurred offshore (p

Matched MeSH terms: Industry
Fulltext Data on Indoor Air Quality (IAQ) in kindergartens with different surrounding activities

Abdullah S, Abd Hamid FF, Ismail M, Ahmed AN, Wan Mansor WN

Data Brief, 2019 Aug;25:103969.
PMID: 31198825 DOI: 10.1016/j.dib.2019.103969

The aim of the measurement of this data is to evaluate the Indoor Air Quality (IAQ) in terms of chemical and physical parameters. Data were collected at three different kindergartens having different surrounding activities (industrial, institutional, residential area). The chemical parameters measured were respirable suspended particulates of PM10, PM2.5, PM1, carbon monoxide and carbon dioxide, and the concentrations are within the acceptable limit. Physical parameters of wind speed are within the standard, while temperature and relative humidity exceeded the acceptable limit. A strong correlation was found between the chemical IAQ parameters with thermal comfort parameters (temperature and relative humidity). The concentration of IAQ pollutants is higher in order of residential > institutional > industrial.

Matched MeSH terms: Industry
Fulltext Research progress in Bioflocculants from bacteria

Abdullah, A.M., Hamidah, H., Alam, M.Z.

International Food Research Journal, 2017;24(101):0-0.
MyJurnal

Although one of the major users of flocculants are water and wastewater treatment industries, flocculants are also used in various food industries. The chemical flocculants are preferred widely in these industries due to low production cost and fast production ability. However, the negative effects of the chemical flocculants should not be neglected to gain the economic benefits only. Therefore, the researchers are working to discover efficient and economical flocculants from biological sources. Several attempts have been made and are still being made to extract or produce bioflocculants from natural sources such as plants, bacteria, fungi, yeast, algae, etc. The review revealed that significant amount of work have been done in the past, in search of bioflocculant. However, commercially viable bioflocculants are yet to be marketed widely. With the advent of new biotechnologies and advances in genetic engineering, the researchers are hopeful to discover or develop commercially viable, safe and environmentfriendly bioflocculants.

Matched MeSH terms: Food Industry
Isolation and characterization of pepsin-solubilized collagen from the integument of sea cucumber (Stichopus vastus)

Abedin MZ, Karim AA, Ahmed F, Latiff AA, Gan CY, Che Ghazali F, et al.

J Sci Food Agric, 2013 Mar 30;93(5):1083-8.
PMID: 22936269 DOI: 10.1002/jsfa.5854

Sea cucumber (Stichopus vastus) is considered an underutilized resource, since only its stomach and intestines are eaten raw as salad in a few countries and the remaining parts, especially the integument rich in collagen, is discarded. Hence a valuable by-product having potential nutraceutical and pharmaceutical applications is wasted. In the present investigation, pepsin-solubilized collagen (PSC) from the integument of S. vastus was isolated, purified and characterized.

Matched MeSH terms: Food-Processing Industry/economics
A Critical Review of the Concept of Transgenic Plants: Insights into Pharmaceutical Biotechnology and Molecular Farming

Abiri R, Valdiani A, Maziah M, Shaharuddin NA, Sahebi M, Yusof ZN, et al.

Curr Issues Mol Biol, 2016;18:21-42.
PMID: 25944541

Using transgenic plants for the production of high-value recombinant proteins for industrial and clinical applications has become a promising alternative to using conventional bioproduction systems, such as bacteria, yeast, and cultured insect and animal cells. This novel system offers several advantages over conventional systems in terms of safety, scale, cost-effectiveness, and the ease of distribution and storage. Currently, plant systems are being utilised as recombinant bio-factories for the expression of various proteins, including potential vaccines and pharmaceuticals, through employing several adaptations of recombinant processes and utilizing the most suitable tools and strategies. The level of protein expression is a critical factor in plant molecular farming, and this level fluctuates according to the plant species and the organs involved. The production of recombinant native and engineered proteins is a complicated procedure that requires an inter- and multi-disciplinary effort involving a wide variety of scientific and technological disciplines, ranging from basic biotechnology, biochemistry, and cell biology to advanced production systems. This review considers important plant resources, affecting factors, and the recombinant-protein expression techniques relevant to the plant molecular farming process.

Matched MeSH terms: Drug Industry

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