Displaying all 14 publications

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  1. Ho CC, Tan HM
    Sex Med Rev, 2013 May;1(1):42-49.
    PMID: 27784559 DOI: 10.1002/smrj.4
    INTRODUCTION: Testosterone treatment for hypogonadism is detrimental for men in reproductive age as it impairs spermatogenesis, and therefore affects fertility. It is, therefore, not indicated in men with hypogonadism and infertility.

    AIM: The aim of this review is to analyze current data regarding options of treatment for men with hypogonadism and infertility.

    MAIN OUTCOMES MEASURES: A comprehensive review of the current literature on management of infertility among hypogonadal men.

    METHODS: A literature search using PubMed from 1980 to 2012 was done on articles published in the English language. The following medical subject heading terms were used: "infertility," "infertile," "hypogonadism;" "testosterone deficiency" and "men" or "male;" and "treatment" or "management."

    RESULTS: The options for hypogonadal testicular failure are limited. Hormonal treatment is by and large ineffective. For secondary hypogonadism (hypogonadotropic/normogonadotropic hypogonadism), the options include gonadotropin-releasing hormone, human chorionic gonadotropin (hCG), human menopausal gonadotropin (hMG), follicle-stimulating hormone (FSH), and anti-estrogens and aromatase inhibitors. Dopamine antagonist is indicated for prolactinoma. Artificial reproductive technique is indicated for primary testicular failure and also when medical therapy fails.

    CONCLUSION: The most suitable option with the current data available is hCG with or without hMG/FSH. Testosterone supplementation should be avoided, but if they are already on it, it is still possible for a return of normal sperm production within 1 year after discontinuing testosterone. Ho CCK and Tan HM. Treatment of the hypogonadal infertile male-A review. Sex Med Rev 2013;1:42-49.

    Matched MeSH terms: Medical Subject Headings
  2. Memon MA, Siddaiah-Subramanya M, Yunus RM, Memon B, Khan S
    Surg Laparosc Endosc Percutan Tech, 2019 Aug;29(4):221-232.
    PMID: 30855402 DOI: 10.1097/SLE.0000000000000655
    BACKGROUND: To explore the clinical outcomes, safety and effectiveness of suture cruroplasty versus mesh repair for large hiatal hernias (HHs) by an updated meta-analysis.

    MATERIAL AND METHODS: Randomized controlled trials evaluating the effects of these 2 treatment modalities were searched from PubMed and other electronic databases between January 1991 and July 2018. The outcome variables analyzed included operating time, complications, recurrence of HH or wrap migration, reoperation, hospital stay and quality of life.

    RESULTS: Five randomized controlled trials totaling 478 patients (suture=222, mesh=256) were analyzed. For reoperation variable, the odds ratio was significantly 3.26 times higher for the suture group. For recurrence of HH, the odds ratio for the suture group was nonsignificantly 1.65 times higher compared with the mesh group. Comparable effects were noted for all other variables.

    CONCLUSIONS: Mesh repair seems to be superior to suture cruroplasty for large HH repair. Therefore, the routine use of mesh may be advantageous in selected cases.

    Matched MeSH terms: Medical Subject Headings
  3. Ambusam S, Baharudin O, Roslizawati N, Leonard J
    Clin Ter, 2015 Nov-Dec;166(6):256-61.
    PMID: 26794814 DOI: 10.7417/CT.2015.1898
    Document holder is used as a remedy to address occupational neck pain among computer users. An understanding on the effects of the document holder along with other work related risk factors while working in computer workstation requires attention. A comprehensive knowledge on the optimal location of the document holder in computer use and associated work related factors that may contribute to neck pain reviewed in this article. A literature search has been conducted over the past 14 years based on the published articles from January 1990 to January 2014 in both Science Direct and PubMed databases. Medical Subject Headings (MeSH) keywords for search were neck muscle OR head posture OR muscle tension' OR muscle activity OR work related disorders OR neck pain AND/OR document location OR document holder OR source document OR copy screen holder.Document holder placed lateral to the screen was most preferred to reduce neck discomfort among occupational typists. Document without a holder was placed flat on the surface is least preferred. The head posture and muscle activity increases when the document is placed flat on the surface compared to when placed on the document holder. Work related factors such as static posture, repetitive movement, prolong sitting and awkward positions were the risk factors for chronic neck pain. This review highlights the optimal location for document holder for computer users to reduce neck pain. Together, the importance of work related risk factors for to neck pain on occupational typist is emphasized for the clinical management.
    Matched MeSH terms: Medical Subject Headings
  4. Lee SW, Loh SW, Ong C, Lee JH
    Ann Transl Med, 2019 Oct;7(19):513.
    PMID: 31728366 DOI: 10.21037/atm.2019.09.32
    The objectives of this review are to describe the limitations of commonly used clinical outcomes [e.g., mortality, ventilation parameters, need for extracorporeal membrane oxygenation (ECMO), pediatric intensive care unit (PICU) and hospital length of stay (LOS)] in pediatric acute respiratory distress syndrome (PARDS) studies; and to explore other pertinent clinical outcomes that pediatric critical care practitioners should consider in future clinical practice and research studies. These include long-term pulmonary function, risk of pulmonary hypertension (PHT), nutrition status and growth, PICU-acquired weakness, neurological outcomes and neurocognitive development, functional status, health-related quality of life (HRQOL)], health-care costs, caregiver and family stress. PubMed was searched using the following keywords or medical subject headings (MESH): "acute lung injury (ALI)", "acute respiratory distress syndrome (ARDS)", "pediatric acute respiratory distress syndrome (PARDS)", "acute hypoxemia respiratory failure", "outcomes", "pediatric intensive care unit (PICU)", "lung function", "pulmonary hypertension", "growth", "nutrition', "steroid", "PICU-acquired weakness", "functional status scale", "neurocognitive", "psychology", "health-care expenditure", and "HRQOL". The concept of contemporary measure outcomes was adapted from adult ARDS long-term outcome studies. Articles were initially searched from existing PARDS articles pool. If the relevant measure outcomes were not found, where appropriate, we considered studies from non-ARDS patients within the PICU in whom these outcomes were studied. Long-term outcomes in survivors of PARDS were not follow-up in majority of pediatric studies regardless of whether the new or old definitions of ARDS in children were used. Relevant studies were scarce, and the number of participants was small. As such, available studies were not able to provide conclusive answers to most of our clinical queries. There remains a paucity of data on contemporary clinical outcomes in PARDS studies. In addition to the current commonly used outcomes, clinical researchers and investigators should consider examining these contemporary outcome measures in PARDS studies in the future.
    Matched MeSH terms: Medical Subject Headings
  5. Noor Ashikin Othman, Mohammad Khatim Hasan
    MyJurnal
    Simulating Lotka-Volterra model using numerical method require researchers to apply tiny mesh sizes to obtain an accurate result. This approach nevertheless increases the complexity and burden of computer memory and consume long computational time. To overcome these issues, we investigate and construct new two-step solver that could simulate Lotka-Volterra model using bigger mesh size. This paper proposes three new two-step schemes to simulate Lotka-Volterra model. A non-standard approximation scheme with trimean approach was adopted. The nonlinear terms in the model is approximated via trimean approach and differential equation via non-standard denominators. Four sets of parameters were examined to analyse the performance of these new schemes. Results show that these new schemes provide better simulation for large mesh size.
    Matched MeSH terms: Medical Subject Headings
  6. Perumal L
    Heliyon, 2019 Aug;5(8):e02319.
    PMID: 31517093 DOI: 10.1016/j.heliyon.2019.e02319
    New techniques are presented for Delaunay triangular mesh generation and element optimisation. Sample points for triangulation are generated through mapping (a new approach). These sample points are later triangulated by the conventional Delaunay method. Resulting triangular elements are optimised by addition, removal and relocation of mapped sample points (element nodes). The proposed techniques (generation of sample points through mapping for Delaunay triangulation and mesh optimisation) are demonstrated by using Mathematica software. Simulation results show that the proposed techniques are able to form meshes that consist of triangular elements with aspect ratio of less than 2 and minimum skewness of more than 45°.
    Matched MeSH terms: Medical Subject Headings
  7. Michal Christina Steven
    Borneo Epidemiology Journal, 2020;1(2):104-115.
    MyJurnal
    Introduction:Plasmodium knowlesi(P.knowlesi) is a zoonotic malaria parasite, transmitted between non-factors” or “individual factors” or “ecological factors” and “P.knowlesi” and “human” including human primate hosts by the Anopheles (An.) mosquitos, and causing spill-over infections in humans where the parasite, vector, host, and human converge
    Methods:The search was done electronically toexplore for appropriate papers viaPubMed, and Science Direct for articles published up to March 2020, containing the words “factors associated” or “environmental synonyms and Medical Subject Heading (MeSH) terms. A total of 27 articles from PubMed Databases and 18 articles from Science Direct were selected to be assessed for eligibility. Out of it, a total of 13 articles were selected to be analysed.
    Results:Host factors such as sex and age, as well as occupation as individual factors, while environmental factors such as rainfall and geographic elevation have some association with P.knowlesiinfection in humans. This zoonotic malaria poses unique challenges that will need to be addressed if all forms of malaria are to be eliminated based on the sustainable development goal (SDG)
    Conclusion:This article highlights the importance of disease ecologies such as climate and landscape and human-environment interactions such as the land use patterns, such as agriculture or infrastructure activities) to reduce the further increase of cases and mortality globally due to P.knowlesiinfection. This review focuses mainly on the host and environmental factors that influence P.knowlesiMalaria Infection in Humans
    Matched MeSH terms: Medical Subject Headings
  8. Zarei M, Qorbani M, Djalalinia S, Sulaiman N, Subashini T, Appanah G, et al.
    Int J Prev Med, 2021;12:8.
    PMID: 34084305 DOI: 10.4103/ijpvm.IJPVM_61_19
    Background: This review seeks to determine the relationship between food insecurity among elderly people over the past decades and nutrient deficiency, which is rather unclear. We aim to systematically review the relationship between food insecurity and dietary intake among elderly population.

    Methods: In this systematic review, we systematically searched the international databases including PubMed, Web of Sciences, and Scopus for scientifically related papers which have been published up until January 2018. For a more refined search, we used the Medical Subject Headings (MeSH) terms and Emtree. In terms of search protocol, no restrictions were placed on time and language. Two independent reviewers conducted the data refining processes. Validated form (PRISMA) was used to conduct quality assessment and data extraction.

    Results: Eight cross sectional studies have been included in this review. Two of the studies were conducted in Asia and the remaining six studies were largely based in the United States and Canada. Food insecurity was associated with low levels of vitamin and mineral intakes such as vitamins E, A, B, and D and also zinc, calcium, magnesium, and iron. Most studies also reported insufficient energy, and micro and macronutrients intake among elderly people.

    Conclusions: The findings of this review evidence a considerable amount of food insecurity and nutrient deficiency, including vitamins E, C, D, B 2, and B 12 and zinc, phosphorus, and calcium among elderly population. These findings could be used as reliable evidence by policy makers and future complementary analyses.

    Matched MeSH terms: Medical Subject Headings
  9. Ho GJ, Liew SM, Ng CJ, Hisham Shunmugam R, Glasziou P
    PLoS One, 2016;11(12):e0167170.
    PMID: 27935993 DOI: 10.1371/journal.pone.0167170
    BACKGROUND: Physicians are often encouraged to locate answers for their clinical queries via an evidence-based literature search approach. The methods used are often not clearly specified. Inappropriate search strategies, time constraint and contradictory information complicate evidence retrieval.

    AIMS: Our study aimed to develop a search strategy to answer clinical queries among physicians in a primary care setting.

    METHODS: Six clinical questions of different medical conditions seen in primary care were formulated. A series of experimental searches to answer each question was conducted on 3 commonly advocated medical databases. We compared search results from a PICO (patients, intervention, comparison, outcome) framework for questions using different combinations of PICO elements. We also compared outcomes from doing searches using text words, Medical Subject Headings (MeSH), or a combination of both. All searches were documented using screenshots and saved search strategies.

    RESULTS: Answers to all 6 questions using the PICO framework were found. A higher number of systematic reviews were obtained using a 2 PICO element search compared to a 4 element search. A more optimal choice of search is a combination of both text words and MeSH terms. Despite searching using the Systematic Review filter, many non-systematic reviews or narrative reviews were found in PubMed. There was poor overlap between outcomes of searches using different databases. The duration of search and screening for the 6 questions ranged from 1 to 4 hours.

    CONCLUSION: This strategy has been shown to be feasible and can provide evidence to doctors' clinical questions. It has the potential to be incorporated into an interventional study to determine the impact of an online evidence retrieval system.

    Matched MeSH terms: Medical Subject Headings
  10. Marilyn Charlene Montini Maluda, Michelle May D. Goroh, Tan, Eric Chee How, Syed Sharizman Syed Abdul Rahim, Richard Avoi, Mohammad Saffree Jeffree, et al.
    MyJurnal
    Introduction: Melioidosis, also known as Whitmore disease, is caused by the gram-negative bacillus, Burkholderia pseudomallei and remains a public health concern in Southeast Asia and northern parts of Australia. This study attempts to identify all possible complications of melioidosis and its outcomes.
    Methods: Literature search was conducted from databases such as PubMed, Science Direct and Scopus from 1st January 2000 to 31st August 2019. Medical Subject Headings (MeSH) search strategy was used with the terms ‘Melioidosis’ or ‘Burkholderia pseudomallei’ and ‘Complications’.
    Results: A total of 162 titles were identified and 22 articles were included in the review. Findings showed that among the 22 articles, the ratio of male to female melioidosis incidence was 2.3 to 1, with most cases (86.4%) aged older than 14 years old and showed a mean age of 46 years old. A third (7/22) of the papers reported the involvement of the nervous system as a complication of melioidosis followed by cardiovascular complications. Among the 23 cases reported, 13 had underlying medical conditions with most of them (84.6%) having diabetes mellitus or newly diagnosed with diabetes mellitus. Overall, only one case (4.3%) had resulted in mortality, while 17.4% developed complications and 78.3% managed a full recovery after undergoing treatment for melioidosis.
    Conclusion: The most commonly found complication of melioidosis involved the nervous system but patient outcomes were favourable. Rare complications included mycotic aneurysm that can be fatal. Melioidosis can affect almost any organ leading to various complications.
    Matched MeSH terms: Medical Subject Headings
  11. Morni WZ, Rahim SA, Rumpet R, Musel J, Hassan R
    Trop Life Sci Res, 2017 Jan;28(1):117-129.
    PMID: 28228920 MyJurnal DOI: 10.21315/tlsr2017.28.1.8
    This study provides the first marine gastropod checklist from the Sarawak Exclusive Economic Zone (EEZ). Gastropod samples were collected from selected stations in the Sarawak EEZ using an otter trawl net with a stretched mesh size of 38 mm at the cod end. The trawling operations were conducted more than 12 nautical miles from the coast, and the area was divided into three depth strata: I) 20-50 m, II) 50-100 m and III) 100-200 m. A total of 23 gastropod species were identified during the two-month sampling period from 16 August until 6 October 2015, representing 8 superfamilies, 15 families and 20 genera. Superfamily Tonnoidea was represented by 7 species, followed by Muricoidea (5 species), Cypraeoidea (4 species), and Buccinoidea and Conoidea (both with 2 species). Other superfamilies were represented by a single species. Only 3 species were obtained in 2 depth strata, namely Melo melo, Murex aduncospinosus and Tonna galea. In addition, 9, 13 and 4 species of gastropods were found in strata I, II and III, respectively. The information on gastropod distributions at different depth strata in the Sarawak EEZ could be useful in updating the Malaysian species diversity database.
    Matched MeSH terms: Medical Subject Headings
  12. Teng CL, Zuhanariah MN, Ng CS, Goh CC
    Med J Malaysia, 2014 Aug;69 Suppl A:4-7.
    PMID: 25417946
    This article describes the methodology of this bibliography. A search was conducted on the following: (1) bibliographic databases (PubMed, Scopus, and other databases) using search terms that maximize the retrieval of Malaysian publications; (2) Individual journal search of Malaysian healthrelated journals; (3) A targeted search of Google and Google Scholar; (4) Searching of Malaysian institutional repositories; (5) Searching of Ministry of Health and Clinical Research Centre website. The publication years were limited to 2000- 2013. The citations were imported or manually entered into bibliographic software Refworks. After removing duplicates, and correcting data entry errors, PubMed's Medical Subject Headings (MeSH terms) were added. Clinical research is coded using the definition "patient-oriented-research or research conducted with human subjects (or on material of human origin) for which the investigator directly interacts with the human subjects at some point during the study." A bibliography of citations [n=2056] that fit the criteria of clinical research in Malaysia in selected topics within five domains was generated: Cancers [589], Cardiovascular diseases [432], Infections [795], Injuries [142], and Mental Health [582]. This is done by retrieving citations with the appropriate MESH terms, as follow: For cancers (Breast Neoplasms; Colorectal Neoplasms; Uterine Cervical Neoplasms), for cardiovascular diseases (Coronary Disease; Hypertension; Stroke), for infections (Dengue; Enterovirus Infections, HIV Infections; Malaria; Nipah Virus; Tuberculosis), for injuries (Accidents, Occupational; Accidents, Traffic; Child Abuse; Occupational Injuries), for mental health (Depression; Depressive Disorder; Depressive Disorder, Major; Drug Users; Psychotic Disorders; Suicide; Suicide, Attempted; Suicidal Ideation; Substance- Related Disorders).
    Matched MeSH terms: Medical Subject Headings
  13. Lee W, Wong CC
    Global Spine J, 2021 Mar;11(2):256-265.
    PMID: 32875872 DOI: 10.1177/2192568220907574
    STUDY DESIGN: Systematic review.

    OBJECTIVE: Anterior-alone surgery has gained wider reception for subaxial cervical spine facets dislocation. Questions remain on its efficacy and safety as a stand-alone entity within the contexts of concurrent facet fractures, unilateral versus bilateral dislocations, anterior open reduction, and old dislocation.

    METHODS: A systematic review was performed with search strategy using translatable MESH terms across MEDLINE, EMBASE, VHL Regional Portal, and CENTRAL databases on patients with subaxial cervical dislocation intervened via anterior-alone approach. Two reviewers independently screened for eligible studies. PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) flow chart was adhered to. Nine retrospective studies were included. Narrative synthesis was performed to determine primary outcomes on spinal fusion and revisions and secondary outcomes on new occurrence or deterioration of neurology and infection rate.

    RESULTS: Nonunion was not encountered across all contexts. A total of 0.86% of unilateral facet dislocation (1 out of 116) with inadequate reduction due to facet fragments between the facet joints removed its malpositioned plate following fusion. No new neurological deficit was observed. Cases that underwent anterior open reduction did not encounter failure that require subsequent posterior reduction surgery. One study (N = 52) on old dislocation incorporated partial corpectomy in their approach and limited anterior-alone approach to cases with persistent instability.

    CONCLUSIONS: This systematic review supports the efficacy and success of anterior reduction, fusion, and instrumentation for cervical facet fracture dislocation. It is safe from a neurological standpoint. Revision rate due to concurrent facet fracture is low. Certain patients may require posteriorly based surgery or in specific cases combined anterior and posterior procedures.

    Matched MeSH terms: Medical Subject Headings
  14. Mohammad Khatim Hasan, Shahrizan Mazlan
    MyJurnal
    Simulating Lotka-Volterra model using a numerical method requires the researcher to apply tiny mesh sizes to come up with an accurate solution. This approach will increase the complexity and burden of computer memory and consume long computational time. To overcome these issues, a new solver is used that could simulate Lotka-Volterra model using bigger mesh size. In this paper, prey and predator behaviour is simulated via Lotka-Volterra model. We approximate the nonlinear terms in the model via weighted average approach and differential equation via nonstandard denominators. We provide three new schemes for one step method and simulate four sets of parameters to examine the performance of these new schemes. Results show that these new schemes simulate better for large mesh sizes.
    Matched MeSH terms: Medical Subject Headings
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