Displaying publications 1 - 20 of 35 in total

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  1. Mukherjee AP, Yuen TK
    Med J Aust, 1971 Jan 30;1(5):257-60.
    PMID: 5545973
    Matched MeSH terms: Nephrotic Syndrome/epidemiology
  2. Sinnathuray TA
    Med J Malaya, 1971 Jun;25(4):253-6.
    PMID: 4261295
    Matched MeSH terms: Nephrotic Syndrome/complications
  3. Sinniah D
    Med J Malaya, 1971 Dec;26(2):84-9.
    PMID: 4260865
    Matched MeSH terms: Nephrotic Syndrome/prevention & control
  4. Chuan PL, Leng SC, Sinniah R
    J Singapore Paediatr Soc, 1975 Oct;17(2):113-23.
    PMID: 1207079
    Matched MeSH terms: Nephrotic Syndrome/drug therapy*; Nephrotic Syndrome/genetics; Nephrotic Syndrome/epidemiology
  5. Murugasu R, Wang F, Dissanaike AS
    Trans R Soc Trop Med Hyg, 1978;72(4):389-91.
    PMID: 705845
    The first living patient with a Schistosoma japonicum-type infection who presented with the nephrotic syndrome is reported in detail. It is not clear whether the nephrotic syndrome was due to the schistosome infection or to the deposition of hepatitis B antigen and antibody complexes. This is the tenth case of schistosomiasis reported from aborigines in Malaysia and a sylvatic source of infection is suggested.
    Matched MeSH terms: Nephrotic Syndrome/etiology
  6. Cheong IKS
    Family Practitioner, 1981;4:28-33.
    Matched MeSH terms: Nephrotic Syndrome
  7. Prathap K, Looi LM
    Ann Acad Med Singap, 1982 Jan;11(1):52-6.
    PMID: 7073229
    Adequately biopsied renal tissue received in the Department of Pathology, University Hospital, Kuala Lumpur from 1,000 consecutive Malaysian patients during an eleven year period between 1970 and 1981 was reviewed. The youngest patient was 6 days old and the oldest 80 years. Both sexes were equally represented. The majority of the patients were Chinese (71%) with Malays and Indians comprising most of the remainder. Over half the patients (50.4%) presented with the nephrotic syndrome. Other modes of presentation included systemic lupus erythematosus, proteinuria and haematuria separately or in combination and hypertension. Minimal change (25.7%) and proliferative glomerulonephritis (24.8%) were present in about equal numbers and together accounted for over half of the cases (50.5%). Lupus nephritis was the third most common diagnosis (18.4%). In addition, there were patients with focal glomerulonephritis (5.4%), membranous glomerulonephritis (5.5%), Berger's disease (5.8%), amyloidosis (0.6%) and end stage renal disease (4.0%).
    Matched MeSH terms: Nephrotic Syndrome/pathology
  8. Segasothy M, Kamal A, Pang KS
    Med J Malaysia, 1983 Jun;38(2):114-7.
    PMID: 6621439
    A 31 year old Chinese man developed the nephrotic syndrome, and wasfound to have some of the clinical features of renal vein thrombosis such as a rapid deterioration in renal function and great variability in proteinuria. Radiological studies confirmed the diagnosis of bilateral renal vein thrombosis. The clinical features and pathogenesis of renal vein thrombosis are discussed.
    Matched MeSH terms: Nephrotic Syndrome/complications*; Nephrotic Syndrome/diagnosis; Nephrotic Syndrome/pathology
  9. Prathap K, Looi LM, Lam KL, Wang F, Chua CT
    Malays J Pathol, 1983 Aug;6:39-49.
    PMID: 6599867
    Matched MeSH terms: Nephrotic Syndrome/pathology*
  10. Cheong IKS
    Family Practitioner, 1983;6:37-40.
    Matched MeSH terms: Nephrotic Syndrome
  11. Abdullah R
    PMID: 3282374
    Nephrotic syndrome is often associated with a hypercoagulable state and thrombotic complications. Thrombosis may be due to a number of abnormalities in blood, including AT III deficiency, increased concentrations of fibrinogen, factors V and VIII, and platelet hyperaggregability. The therapeutic approach to thrombosis in nephrotic syndrome is the use of anticoagulants as a preventive measure or an attempt at thrombolysis with streptokinase, urokinase, or stanozolol.
    Matched MeSH terms: Nephrotic Syndrome/blood; Nephrotic Syndrome/complications; Nephrotic Syndrome/veterinary*
  12. Kong NCT, Cheong IKS, Chong SM, Suleiman AB, Morad Z, Lajin I, et al.
    Med J Malaysia, 1988 Sep;43(3):200-5.
    PMID: 3241577
    Between 1980-1986, 219 renal biopsies were performed on patients with lupus nephritis (LN) presenting at the General Hospital, Kuala Lumpur. There were 172 (78.5%) females and 47 (21.5%) males. The ethnic distribution of 48.4% Malays, 46.1% Chinese and 5.5% Indians reflected their proportional composition in the general population. Peak incidence (40.6%) of cases occurred in the third decade of life (20-29 group) followed by 26.5% and 20.1% in the second and fourth decades respectively. The median age was 24 for females and 27 for males. In both sexes, nephrotic syndrome was the commonest mode of presentation (62.2%) followed by proteinuria (20.5%). Acute oliguric renal failure occurred in 11 patients (5%) and 8 of these showed crescentic glomerulonephritis with more than 50% crescents. The commonest histological picture was diffuse proliferative LN (WHO Stage IV-44.7%) which included 70% (19/27) of those with crescentic disease. This was followed by membranous LN (28.8%) of which 6 (all males) had crescentic disease. 7 (12.3%) of our patients had crescentic nephritis with a female to male distribution of 14: 13, suggesting either more aggressive disease or delayed diagnosis in males.
    Key words - Renal biopsies, lupus nephritis, nephrotic syndrome, proteinuria.
    Matched MeSH terms: Nephrotic Syndrome/etiology
  13. Gangaram HB, Cheong IK
    Med J Malaysia, 1993 Dec;48(4):446-8.
    PMID: 8183171
    We report a 14 year old Indian-Muslim girl who developed a fulminant, disseminated and fatal varicella infection while receiving steroids for nephrotic syndrome. The terminal phase of her illness was complicated by a bleeding dyscrasia and circulatory collapse. Varicella infection in healthy children is a benign disease. However in neonates and immunosuppressed patients it may be severe and often fatal. There are many reports of fatalities occurring in cancer patients receiving chemotherapy, patients on immunosuppressives for asthma, haemolytic anaemia, rheumatic fever, and renal and bone marrow transplantation. Patients with nephrotic syndrome receiving cyclophosphamide treatment are at particular risk of developing severe chickenpox infection. To our knowledge, there has been only one report of fatal chickenpox infection in a child who received steroids for nephrotic syndrome. We report here a case of fatal haemorrhagic chickenpox complicating nephrotic syndrome.
    Matched MeSH terms: Nephrotic Syndrome/complications*; Nephrotic Syndrome/drug therapy
  14. Zainal D, Riduan A, Ismail AM, Norhayati O
    PMID: 8525403
    Renal biopsy is essential in the management of renal parenchymal diseases. Thus far there is no publish report on the pattern of glomerulonephritis in Kelantan. We decided to establish the pattern of glomerulonephritis in Kelantan and use this information as our reference in future studies. Records of patients who had proven glomerulonephritis histologically were analysed. Their biological data, clinical presentation, etiology and clinicopathological pattern were studied. Where appropriate mean and standard deviation were calculated. A total of 74 biopsies were performed during the study period (between January 1991 and December 1993), out of which 72 biopsies (97.3%) were considered suitable for analysis. The male to female ratio was 1:1.1. Mean age at presentation was 27.6 +/- 12.2 years. Nephrotic syndrome was the commonest clinical presentation (65.3%). The main underlying cause was systemic lupus erythematosus (50%) followed by primary glomerulonephritis. Histologically, IgA nephropathy and minimal change disease were the main patterns among patients with primary glomerulonephritis while diffuse proliferative glomerulonephritis was the commonest pattern among patients with lupus nephritis. Hence the pattern of glomerulonephritis is similar to other reported series. The procedure is considered safe and has a high success rate.
    Matched MeSH terms: Nephrotic Syndrome/etiology
  15. Van Rostenberghe H, Nik Abidin NZ, Samarendra S
    MyJurnal
    During a period of three years (February 1995 --January 1998), 30 biopsies were performed for patients within the paediatric age group in Hospital Universiti Sains Malaysia (HUSM). The majority of these patients (19 cases) had steroid-resistant Nephrotic Syndrome. Other indications were lupus erythematosus (5 cases), acute or chronic glomerulonephritis (5 cases) and infantile nephrotic syndrome (1 case). The biopsy of the 19 cases of steroid-resistant nephrotic syndrome gave the following findings: 10 showed minimal- change nephrotic syndrome, 4 focal segmental glomerulosclerosis, 3 mesangial proliferative glomerulonephritis and one diffuse sclerosing glomerulonephritis while there was insufficient glomeruli for a conclusive diagnosis in one case. The 5 patients with acute/chronic glomerulonephritis showed diffused sclerosing glomerulonephritis. The other 5 patients with lupus nephritis showed mesangial proliferative glomerulonephritis (2) and severe proliferative glomerulonephritis (3). The 5-month-old child with infantile nephrotic syndrome showed mesangial proliferative glomerulonephritis. There were no severe complications noted during or immediately after the procedure. There were 3 cases of gross haematuria, one lasting less than 24 hours and the other two less than
    Matched MeSH terms: Nephrotic Syndrome
  16. Cheah PL, Looi LM, Ghazalli R, Chua CT
    Malays J Pathol, 1999 Jun;21(1):59-62.
    PMID: 10879280
    A 31-year-old Malay female presented with nephrotic syndrome without renal impairment. Renal biopsy features were in keeping with immunotactoid glomerulopathy (ITG). Non-Congophilic deposits were seen causing thickening of the glomerular capillary basement membrane with segmental accentuation, and widening of the mesangium. Immunofluorescence examination showed moderate amounts of IgG and C3 in the glomerular capillary walls with some in the mesangium. Ultrastructurally, 20-nm thick fibrils with microtubular organisation were present predominantly in the subendothelial region with similar fibrils in the mesangium. Although immunotactoid glomerulopathy and fibrillary glomerulonephritis (FG) have been recognised as entities with extracellular fibrillary material in the kidney, to date much remains to be clarified regarding these 2 conditions. While the renal biopsy findings in this patient are consistent with ITG, her clinical presentation is unlike that of usual ITG in that she is of a much younger age and has no associated haemopoietic disorder. Response to initial treatment of 8 weeks of prednisolone therapy was poor.
    Matched MeSH terms: Nephrotic Syndrome/complications; Nephrotic Syndrome/pathology
  17. Suresh RL, Suryati Y, Merican I
    Med J Malaysia, 2003 Oct;58(4):594-6.
    PMID: 15190636
    Chronic hepatitis C manifests with many extrahepatic features including renal involvement. However, less commonly, interferon therapy for chronic hepatitis C can also result in renal involvement and we describe a case when interferon therapy resulted in minimal change glomerulopathy, a form of involvement which, carries a good prognosis. Our patient developed nephrotic syndrome while on interferon therapy and HCV RNA levels were undetectable at that time. The disease showed excellent response to steroid therapy.
    Matched MeSH terms: Nephrotic Syndrome/chemically induced*
  18. Soehardy Z, Hayati SN, Rozita M, Rohana AG, Halim AG, Norella K, et al.
    Med J Malaysia, 2006 Oct;61(4):484-6.
    PMID: 17243528 MyJurnal
    Membranous glomerulonephritis (MGN) is one of the common forms of nephrotic syndrome in the adult population. The majority of MGN are idiopathic, but the secondary forms can be seen in the setting of autoimmune disease, neoplasia, infection and following exposure to certain therapeutic agents. Histologically, MGN is an immunologically mediated disease in which immune complexes deposit in the subepithelial space. Syphilis is a venereal disease that can also be acquired by exposure to infected blood. Untreated syphilis may progress and develop renal complications such as membranous glomerulonephritis (MGN) or diffuse endocapillary glomerulonephritis with or without crescent formation. Today, with increasing awareness of sexually transmitted diseases especially HIV infection coupled by the practice of protected sexual intercourse and advancement of medicine, we have seen fewer and fewer cases of acquired syphilis. Furthermore, majority will present with typical syphilitic symptoms of such as chancre, rash, fever and lymph node enlargement in which case the diagnosis is easily obtained. We are reporting a case of acquired syphilis masquerading as membranous glomerulonephritis without typical syphilitic symptoms.
    Matched MeSH terms: Nephrotic Syndrome/diagnosis
  19. Bee PC, Gan GG, Sangkar VJ, Haris AR
    Med J Malaysia, 2008 Mar;63(1):71-2.
    PMID: 18935742 MyJurnal
    Nephrotic syndrome (NS) is a well documented complication after allogeneic peripheral blood stem cell transplantation. It is usually due to autoimmune glomerulonephritis and thought to be a clinical manifestation of graft versus host disease. NS has also been reported to be associated with other hematological malignancies. We report a case of nephrotic syndrome in a patient who relapsed after allogeneic peripheral blood stem cell transplantation (PBSCT) for chronic myeloid leukemia (CML). The renal biopsy was suggestive of minimal change disease. There was no other evidence of graft versus host disease. He was treated with high dose prednisolone, with no response and finally succumbed to the underlying disease.
    Matched MeSH terms: Nephrotic Syndrome/etiology*
  20. Koh KH, Tan C, Tan S, Ngu L
    Nephrology (Carlton), 2009 Sep;14(6):622.
    PMID: 19712262 DOI: 10.1111/j.1440-1797.2008.01001.x
    Matched MeSH terms: Nephrotic Syndrome/complications*
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