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  1. Fulltext Wound healing activity of Elaeis guineensis leaf extract ointment
    Sasidharan S, Logeswaran S, Latha LY
    Int J Mol Sci, 2012;13(1):336-47.
    PMID: 22312255 DOI: 10.3390/ijms13010336
    Elaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extract had potent wound healing capacity as evident from the better wound closure (P < 0.05), improved tissue regeneration at the wound site, and supporting histopathological parameters pertaining to wound healing. Matrix metalloproteinases expression correlated well with the results thus confirming efficacy of E. guineensis in the treatment of the wound. E. guineensis accelerated wound healing in rats, thus supporting its traditional use. The result of this study suggested that, used efficiently, oil palm leaf extract is a renewable resource with wound healing properties.
    Matched MeSH terms: Ointments/pharmacology*; Ointments/chemistry
  2. Fulltext Wear properties of paste boronized 316 stainless steel before and after shot blasting process
    Muhamad Hafizuddin Mohamad Basir, Bulan Abdullah, Siti Khadijah Alias
    Scientific Research Journal, 2014;11(2):0-0.
    MyJurnal
    This research investigates and analyzes wear properties of 316 stainless steel before and after applying paste boronizing process and to investigate the effect of shot blasting process in enhancing boron dispersion into the steel. In order to enhance the boron dispersion into 316 stainless steel, surface deformation method by shot blasting process was deployed. Boronizing treatment was conducted using paste medium for 8 hours under two different temperatures which were 8500 C and 9500 C. Wear behaviour was evaluated using pin-on-disc test for abrasion properties. The analysis on microstructure, X-ray Diffraction (XRD) and density were also carried out before and after applying boronizing treatment. Boronizing process that had been carried out on 316 stainless steel increases the wear resistance of the steel compared to the unboronized 316 stainless steel. The effect of boronizing treatment together with the shot blasting process give a greater impact in increasing the wear resistance of 316 stainless steel. This is mainly because shot blasted samples initiated surface deformation that helped more boron dispersion due to dislocation of atom on the deformed surface. Increasing the boronizing temperature also increases the wear resistance of 316 stainless steel. In industrial application, the usage of the components that have been fabricated using the improved 316 stainless steel can be maximized because repair and replacement of the components can be reduced as a result of improved wear resistance of the 316 stainless steel.
    Matched MeSH terms: Ointments
  3. Fulltext Therapeutic effects of conditioned - DPBS from amniotic stem cells on lactating cow mastitis
    Ting WJ, Shaw SW, Hii LY, Lin TY, Chang SC, Liu KY, et al.
    Taiwan J Obstet Gynecol, 2020 Jul;59(4):520-526.
    PMID: 32653123 DOI: 10.1016/j.tjog.2020.05.009
    OBJECTIVE: Bovine mastitis results in economic loss due to decrease in milk production. Antibiotic ointments are commonly used for treating. However, residue and anti-microbial resistance warranted attention progressively. Fortunately, stem cell anti-inflammatory properties and paracrine expression of cytokines accelerates wound healing and suppresses inflammatory reactions in mastitis. The objective of this study is to use the conditioned-Dulbecco's pluripotent stem cells (DPBS) from amniotic membrane stem cells (AMSCs) in treating bovine mastitis.

    MATERIALS AND METHODS: The cows with mastitis were divided into two groups. In antibiotic control group, the cows were given tetraneomycin ointment. In conditioned-DPBS of AMSCs treatment group, amniotic membrane was collected for AMSCs after delivery. With expression of surface antigen and potential of tri-linage differentiation, AMSCs were injected into mammary glands. Then, milk was sampled every three days to monitor the effect of both treatments. The quality of milk was measured with pH, titratable acidity, free calcium ions and somatic cell count.

    RESULTS: Our results demonstrated the Bovine AMSCs expressed CD44, low levels of CD4 and no CD105. Bovine AMSCs demonstrated the differentiation capability in the tri-cell lineages. Mastitis treatment with conditioned-DPBS from AMSCs (experimental group) and conventional antibiotics (control group) showed insignificant difference in pH value and titratable acidity. The level of ionic calcium concentration in the conditioned-DPBS group decreased from 3rd day to 12th day, while the level in the antibiotic group decreased from 0 day to 12th day. The somatic cell number was similar in both groups, which meet the standard of Taiwan milk collection.

    CONCLUSION: In conclusion, conditioned-DPBS from bovine AMSCs has the therapeutic potential to treat bovine mastitis and may replace antibiotics therapy in the future.

    Matched MeSH terms: Ointments
  4. The wound healing properties of Channa striatus-cetrimide cream-wound contraction and glycosaminoglycan measurement
    Baie SH, Sheikh KA
    J Ethnopharmacol, 2000 Nov;73(1-2):15-30.
    PMID: 11025135
    Haruan has been proved to influence the different phases of wound healing process. The current research focuses on the effects of haruan on the different constituents of extracellular matrix of healing wounds in normal and diabetic rats. Anaesthetized normal and streptozotocin induced diabetic rats were provided with excision wounds at the back and then animals were divided into four groups as: group 1, wounds treated with cetrimide+haruan cream; group 2, wounds treated with haruan cream; group 3, wounds treated with cetrimide (commercial) cream; and group 4, wounds untreated and served as control. Animals were sacrificed after 3, 6, 9 and 12 days. These wounds were used to determine the hexosamine, protein, uronic acid and glycosaminoglycan contents and the wound contraction. The results suggested a marked increase (P<0.05) in the uronic acid, hexosamine and dermatan sulfate contents on day 3 of group 1 when compared with groups 2-4. Wound contraction of group 1 was also markedly enhanced of group 1 (P<0.01) when compared with groups 2- 4. On the basis of these results, we conclude that haruan enhances the synthesis of different glycosaminoglycans in healing wounds, which are the first component of extracellular matrix to be synthesized during the wound healing process. The enhanced levels of glycosaminoglycans may help in the formation of a resistant scar and enhanced wound contraction represents the positive influence of haruan on the fibroplastic phase of wound healing.
    Matched MeSH terms: Ointments
  5. The wound healing properties of Channa striatus-cetrimide cream-- tensile strength measurement
    Baie SH, Sheikh KA
    J Ethnopharmacol, 2000 Jul;71(1-2):93-100.
    PMID: 10904151
    Channa striatus, a fresh water snakehead fish, is reported to enhance dermal wound healing. Biochemical components such as amino acids and fatty acids are important for the synthesis of collagen fibers during wound healing. Arachidonic acid, a precursor of prostaglandin plays a vital role in healing the wounds. Haruan (C. striatus) contains all the essential amino acids for wound healing particularly glycine as well as high contents of arachidonic acid and polyunsaturated fatty acids that can promote prostaglandin synthesis. In the present work we have studied the wound healing effect of C. striatus in Sprague-Dawley rats. Cream formulations having different haruan fish extract concentrations as the active ingredient were prepared and stabilized, and they were applied to the wounds. The healing of wounds was characterized by an increase in the tensile strength of the skin, determined on the 7th post-operative day in each case. Haruan treatment of wounds promotes remodeling of collagen, by the synthesis of inter- and intra-molecular protein crosslinking and thus produces a marked increase (P<0.05) in tensile strength as compared to the cetrimide treated group. On the basis of our experiment we conclude that C. striatus helps in wound healing as indicated by the increase in tensile strength. We hypothesise that this effect may be due to its high content of arachidonic acid, glycine and polyunsaturated fatty acids. The mechanism of wound healing will be investigated in future studies.
    Matched MeSH terms: Ointments
  6. The properties of jelly candy made of acid-thinned starch supplemented with konjac glucomannan or psyllium husk powder
    Habilla, C., Sim, S.Y., Nor Aziah, Cheng, L.H.
    International Food Research Journal, 2011;18(1):213-220.
    MyJurnal
    In this study, acid-thinned starch was blended with konjac glucomannan or psyllium husk powder at a concentration of 3% w/w (starch basis). The blends were characterized by pasting analysis and rheological
    properties evaluation. Jelly candy was made from the blends and textural characteristics were studied. Pasting analysis showed that both gums were found to significantly increase some of the pasting parameters, such as peak viscosity, trough, breakdown, final viscosity and setback values. From the frequency sweep, it was found that addition of konjac glucomanan or psyllium husk powder increased the storage modulus (G’) and loss modulus (G’’) values, with psyllium added sample showing more prominent effect than konjac added ones, when compared to the control samples. All samples were found to demonstrate thixotropic flow behaviour. Jelly candy texture profile analysis revealed that konjac glucomannan or psyllium husk powder addition, although decreasing chewability, but rendered the jelly candy less sticky.
    Matched MeSH terms: Ointments
  7. Fulltext Textural properties of laksa noodle as affected by rice flour particle size
    Nura, M., Kharidah, M., Jamilah, B., Roselina, K.
    International Food Research Journal, 2011;18(4):1309-1312.
    MyJurnal
    This study examined the physicochemical properties of rice flours with five different particle sizes (≤63, 80, 100, 125, and 140 μm) prepared by dry milling and their effects on textural properties of laksa noodles. Rice flour with the smallest particle size had the highest water absorption index, peak viscosity, hot paste viscosity, breakdown, final or cold paste viscosity and gel hardness, but the lowest gelatinization temperature. Reduction of rice flour particle size improved textural properties of laksa noodle. Laksa noodle produced from rice flour with the smallest particle size had the best textural properties.
    Matched MeSH terms: Ointments
  8. Fulltext Synthesis of nanopartical-based binary oxide electrode tio2-zro2 with carrot-derived natural dye extract for dye sensitized solar cell (DSSC) application
    Win, S. Y., Win, T. T., Maung, Y. M., Soe, K. K. K., Kyaw, T. T., Tan, C. K., et al.
    Pertanika Journal of Science & Technology, 2015;23(1):119-125.
    MyJurnal
    Dye-sensitized solar cell (DSSC) is the third generation of thin film solar cell. In this work, carrot fruit dye was prepared and used in DSSC as a sensitizer. TiO2–ZrO2 fine binary oxide was mechanochemically prepared and made paste. TiO2–ZrO2 paste (colloidal) was deposited onto FTO/glass in two ways, i.e. as single and double coatings by rolling method. It was immersed in the carrot solution to get dyed cell. The dyed TiO2-ZrO2-FTO/glass cell was offset with the FTO/glass cell coated with adhesive carbon paste. Photovoltaic properties of prepared TiO2–ZrO2 DSSC cell were measured. Results showed that the efficiency of double coating cell was greater than that of the single coating cell. According to the fill factor from the experiments, both the DSSC cells were acceptable for industrial requirement. Hence, it can be concluded that the results obtained were acceptable in the use of cost-effective and eco-favourable dye-sensitized solar cell.
    Matched MeSH terms: Ointments
  9. Synergistic cytotoxic effects of combined δ-tocotrienol and jerantinine B on human brain and colon cancers
    Abubakar IB, Lim KH, Kam TS, Loh HS
    J Ethnopharmacol, 2016 May 26;184:107-18.
    PMID: 26947901 DOI: 10.1016/j.jep.2016.03.004
    The genus Tabernaemontana has widespread distribution throughout tropical and subtropical parts of the world, i.e. Africa, Asia and America which has long been used for treatments of different disease conditions including tumours, wounds, syphilis, stomach ache and headache. Some Tabernaemontana species are used for treatment of piles, spleen and abdominal tumours in India. In particular, the leaf of Tabernaemontana corymbosa is used for treatment of tumours in Bangladesh. Parts of the plant or whole plants are used as decoctions, steam bath, powder and ointments.
    Matched MeSH terms: Ointments
  10. Fulltext Some physico-chemical qualities and acceptability of fermented curry paste
    Abolhassani, Y, Khan, M.A., Salam, A.B, Ghasem, M.
    International Food Research Journal, 2009;16(4):581-588.
    MyJurnal
    The effects of lactic acid bacteria (Lactobacillus plantarum and Lactobacillus bulgaricus) inoculation
    on the sensory attributes and consumers acceptance of fermented curry paste compared with uncultured sample were assessed. pH, titratable acidity (TA) and color changes, during four-month storage were monitored. Hedonic test was utilized to evaluate consumer perception and acceptability of fermented and ordinary curry pastes. Rapid pH drop was observed in inoculated sample with Lb. plantarum presenting better performance than the Lb. bulgaricus. Titratable acidity increased significantly (p0.05) in most of the attributes of
    original recipe and fermented curry paste except for color and sweetness. In summary, this study showed fermented curry paste with Lb. plantarum and Lb. bulgaricus exhibited new sensory attributes encouraging acceptability by consumers.
    Matched MeSH terms: Ointments
  11. Public Knowledge, Attitude, and Perception Toward Conventional and Novel Ocular Treatment in Malaysia
    Abdullah SN, Mohmad Sabere AS
    J Pharm Bioallied Sci, 2020 12 21;13(1):143-147.
    PMID: 34084061 DOI: 10.4103/jpbs.JPBS_463_20
    One of the major concerns in any pharmacological treatment is the patients' adherence to medication. However, different types of ocular dosage forms might result in different response and compliance from the patients. This study investigated and compared public willingness on different types of dosage forms available for ocular treatment. The study also evaluated their willingness on new approach for the treatment based on their knowledge, attitude, and perception. This study was conducted between October and December 2017 through a set of questionnaires applied to 90 respondents between the age of 18 and 60 years who lived in Muar and Kuantan, Malaysia. The results were analyzed using SPSS software version 22.0 including inferential and descriptive statistics. There was no significant difference in the knowledge level between all age groups towards different types of dosage forms available; eye drops (P = 0.09), eye ointment (P = 0.252), medicated contact lens (P = 0.05), ocular mini-tablets (P = 0.06), and ocular inserts (P = 0.075). There is a variation of results among the public towards different types of dosage forms with their willingness to try conventional and novel approach. Eye drops show the highest willingness followed by eye ointment (less willingness). However, most of them showed no willingness towards medicated contact lens, ocular mini-tablets, and ocular insert. This research hopes to provide an overview on the development process of new formulation and dosage forms based on the patients' willingness level in an attempt to increase patient compliance.
    Matched MeSH terms: Ointments
  12. Fulltext Preliminary observations of a natural eye ointment from Curcuma aromatica to treat goat keratoconjunctivitis and uveitis
    Shankar Ganesh, K.
    Jurnal Veterinar Malaysia, 2017;29(2):25-26.
    MyJurnal
    The livestock industry has been relying merely on chemically synthesized antibiotic for eye infections as sprays and ointment. A natural remedy from Curcuma spp. has been tested for efficacy in curing keratoconjunctivitis and uveitis. A severe case of uveitis has been cured within 7 days, with impaired vision restored. These results are observations of a preliminary study conducted in a goat with uveitis.
    Matched MeSH terms: Ointments
  13. Fulltext Physico-chemical and flowability characteristics of a new variety of Malaysian sweet potato, VitAto Flour
    Mohd Hanim, A.B., Chin, N.L., Yusof, Y.A.
    International Food Research Journal, 2014;21(5):2099-2107.
    MyJurnal
    Proximate, functional and pasting properties of a new variety of sweet potato, VitAto, flour, known for its high vitamin A contents, were compared with two other commercial sweet potatoes, Bukit Naga and Okinawan, flour available in Malaysia. The recoveries of each sweet potato from milling were not significantly different at about 20% but in proximate analysis, the VitAto presented the highest protein (5.7%) and dietary fiber (14.8%) contents with more energy 399.6 kcal/100 g produced. The VitAto flour has average particle size of 132.04 μm. The pasting temperature of the VitAto flour was 65oC, with highest setback and trough viscosity values of 530.90 and 197.20 mPa.s, respectively. The flour is classified as easy flowing and stable powders. This study provides information which helps in the handling, packing and storage of sweet potato flours. It also shows that the VitAto flour has an array of functional, pasting and proximate properties that can facilitate its uses in many areas with better nutritional properties.
    Matched MeSH terms: Ointments
  14. Pasting and leaching properties of irradiated starches from various botanical sources
    Mohd Adzahan, N., Mat Hashim, D., Muhammad, K., Abdul Rahman, R., Ghazali, Z., Hashim, K.
    International Food Research Journal, 2009;16(3):415-429.
    MyJurnal
    Changes to the physicochemical properties of wheat, sago and tapioca starches subjected to gamma ray, electron beam and microwave irradiations and the conditions that lead to wheat starch having leaching behaviour similar to sago or tapioca starch were studied. The properties were characterised through swelling and leaching behaviours of the starch granules and retrogradation following pasting. The leaching of wheat starch increased tremendously and resulted in amylose to amylopectin ratios in the leachate similar to that of native sago and tapioca starches. This observation is significant as wheat starch is known to have a leachate composition of mostly amylose. This opens up the possibility of utilising wheat starch in snacks where tapioca and sago starch are commonly used. It was observed that the required conditions for such changes were exposure to microwave for 8 and 10 minutes, electron beam at 5 and 10 kGy and gamma ray at 5 kGy.
    Matched MeSH terms: Ointments
  15. Fulltext Orbital Cellulitis Secondary to Dental Abscess in Children
    Abdul Satar H, Yaakub A, Md Shukri N, Ahmad Tajudin LS
    Cureus, 2021 Apr 09;13(4):e14392.
    PMID: 33981511 DOI: 10.7759/cureus.14392
    Paediatric orbital cellulitis is a potential sight- and life-threatening condition. It is a serious infection in children that can result in significant complications, including blindness, cavernous sinus thrombosis, cerebral venous sinus thrombosis, meningitis, subdural empyema, and brain abscess. Of the patients with orbital cellulitis, 17% died from meningitis, and 20% of the survivors had permanent loss of vision. Therefore, the potential for sight- and life-threatening complications makes prompt diagnosis and early treatment very important. We report here a case of a two-year-old girl who presented with a three-day history of left periorbital swelling, preceded by left upper perioral swelling that extended upward to the left cheek and left lower lid and was associated with low-grade fever. The patient had been admitted and was treated as having left preseptal with facial cellulitis; the patient was started on intravenous amoxicillin/clavulanic acid (200 mg three times per day dose), and chloramphenicol ointment was applied to the periorbital area. On day 3, the condition worsened, and dental examination showed multiple dental caries, upper gum swelling and abscess, and mobility of teeth 61 and 62 (two baby teeth). Contrast-enhanced computed tomography (CECT) of the orbit, paranasal, and brain showed a left periosteal abscess collection extending to the inferomedial region of the orbit. Examination and tooth extraction were performed under general anesthesia. The intraoperative results showed the presence of a left upper gum abscess, which was possibly the primary source of infection. Clinical improvement was observed postoperatively. Orbital cellulitis can be a complication of a dental abscess. This case emphasizes the importance of primary tooth care in children. A lack of care can result in fatal complications.
    Matched MeSH terms: Ointments
  16. Fulltext Optimization of soaking conditions for the production of seaweed (Kappaphycus alverazii) paste using response surface methodology
    Siah, W. M., Aminah, A., Ishak, A.
    International Food Research Journal, 2014;21(2):471-477.
    MyJurnal
    The effects of soaking conditions on the quality characteristics of seaweed paste of Kappaphycus alverazii species were studied. Response Surface Methodology (RSM) with a 2-factor, 5-level central composite design (CCD) was conducted to determine the optimum soaking conditions. The interactive effect of dry seaweed: soaking water ratio (X1 = 1: 15-50) and soaking duration (X2 = 30-120 min) on the gel strength (g), whiteness, expansion (%), moisture content (%) and protein content (g/100 g) of the paste were determined. Results showed that the experimental data could be adequately fitted into a second-order polynomial model with multiple regression coefficients (R2) of 0.8141, 0.9245, 0.9118, 0.9113 and 0.9271 for the gel strength, whiteness, expansion, moisture content and protein content, respectively. The gel strength, whiteness, expansion, moisture content and protein content of seaweed paste were dependent on the ratio of dry seaweed to soaking water and also soaking duration. The proposed optimum soaking conditions for the production of seaweed paste is at a ratio of 1:15 (dry seaweed : soaking water) and soaking duration of 117.06 min. Based on the result obtained, the RSM demonstrated a suitable approach for the processing optimization of Kappaphycus alverazii paste.
    Matched MeSH terms: Ointments
  17. Ointment tacrolimus for steroid resistant adenoviral nummular keratitis
    Jamaluddin Ahmad M, Lott PW, Khaliddin N, Singh S
    Med J Malaysia, 2020 07;75(4):461-463.
    PMID: 32724020
    A 33-year-old man presented with a four-day history of redness and blurring of vision of the right eye. A clinical diagnosis of adenoviral keratitis was made with a differential of microsporidia epithelial keratitis. The patient subsequently developed nummular keratitis which was resistant to topical steroids. He continued to develop multiple recurrences of the condition. Treatment with tacrolimus ointment was started as the patient had an elevated intraocular pressure due to prolonged steroid use. Tacrolimus ointment showed a favourable outcome in the management of recurrent nummular keratitis.
    Matched MeSH terms: Ointments/therapeutic use*
  18. Nanoparticle-based therapies as a modality in treating wounds and preventing biofilm
    Dua K, Gupta G, Chellapan DK, Bebawy M, Collet T
    Panminerva Med, 2018 Dec;60(4):237-238.
    PMID: 30563307 DOI: 10.23736/S0031-0808.18.03435-3
    Matched MeSH terms: Ointments
  19. Momordica charantia ointment accelerates diabetic wound healing and enhances transforming growth factor-β expression
    Hussan F, Teoh SL, Muhamad N, Mazlan M, Latiff AA
    J Wound Care, 2014 Aug;23(8):400, 402, 404-7.
    PMID: 25139598 DOI: 10.12968/jowc.2014.23.8.400
    Transforming growth factor-β (TGF-β) plays an important role in wound healing. Delayed wound healing is a consequence of diabetes, leading to high morbidity and poor quality of life. Momordica charantia (MC) fruit possesses anti-diabetic and wound healing properties. This study aimed to explore the changes in TGF-β expression in diabetic wounds treated with topical MC fruit extract.
    Matched MeSH terms: Ointments/therapeutic use
  20. Fulltext Microbial and quality attributes of thermally processed chili shrimp paste
    Sobhi, B., Noranizan, M., Ab Karim, S., Abdul Rahman, R., Bakar, J., Ghazali, Z.
    International Food Research Journal, 2012;19(4):1705-1712.
    MyJurnal
    Chili shrimp paste (CSP) is a favorite condiment in Southeast Asia. Microbial spoilage makes CSP unsuitable for consumption within several days. Thermal treatment was applied to produce microbiologically safe CSP. The effect of heating process on physicochemical and sensorial properties of CSP was studied. Heating at the optimum condition (21.6 min, 80 ˚C) has been shown effective and reliable in controlling microorganisms in CSP. Complete inactivation of peroxidase activities could not be accomplished at the optimal point, and significant reduction of the total phenolic and capsaicinoids contents was observed. Sensorial evaluation indicated that thermally processed CSP was less preferred by panelists when compared to freshly prepared samples of dry weight respectively.
    Matched MeSH terms: Ointments
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