Displaying publications 1 - 20 of 392 in total

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  1. 137Cs and 40K in the flesh of fish of the Indian Ocean and the Straits of Malacca
    Lowe BG
    Health Phys, 1979 Jun;36(6):723-4.
    PMID: 468543
    Matched MeSH terms: Potassium Radioisotopes/analysis*
  2. 137Cs and 40K levels in marine species caught in Malaysian waters
    Dougherty G, Ng CE
    Health Phys, 1982 Dec;43(6):915-9.
    PMID: 7152953
    Matched MeSH terms: Potassium Radioisotopes/analysis*
  3. 5-aminolevulinic acid induces regulation in growth, yield and physiobiochemical characteristics of wheat under water stress
    Nudrat Aisha Akram, Shamim Kausar, Naila Farid, Muhammad Ashraf, Muhammad Ashraf, Fahad Al-Qurainy
    Sains Malaysiana, 2018;47:661-670.
    The production of wheat crop is below average in many regions of the world which is ascribed to adverse environmental
    conditions including drought stress. The present study was conducted to appraise the beneficial role of exogenouslyapplied
    5-aminolevulinic acid (ALA) on growth, yield and some key physio-biochemical characteristics of two commercially
    important wheat cultivars (Shafaq-06 and Uqab-2000) under well watered [100% field capacity (FC)] and water-deficit
    (60 and 80% FC) conditions. Imposition of varying water regimes significantly decreased fresh and dry weights of shoots,
    photosynthetic pigments (a and b), non-photochemical quenching of chlorophyll fluorescence (NPQ), quenching coefficient
    for non-photochemical (N) of chlorophyll fluorescence (qN), K+ (potassium ion), Ca2+ (calcium ion) and P (phosphorus)
    accumulation in shoot and root and yield-related attributes. In contrast, water deficit regimes caused improvement in
    Fv/Fm (chlorophyll fluorescence measurement), coefficient of photochemical quenching (qP), proline, glycinebetaine
    (GB) and hydrogen peroxide (H2O2) contents. Foliar spray of ALA at the rate of 50, 100 and 150 mg/Lalong with control
    (no spray (NS) and/or water spray (WS)) significantly enhanced chlorophyll a and b pigments, qN, NPQ, qP, K+, Ca2+
    and P accumulation in both roots and shoots, proline, GB, total phenolics and malondialdehyde (MDA) contents and
    yield. The wheat Shafaq-06 was better in shoot dry weight, qN, NPQ and Fv/Fm, shoot and root K+, root Ca2+, proline,
    GB accumulation and yield attributes, while Uqab-2000 was better in chlorophyll a contents, root P and MDA contents.
    Overall, better growth and yield of Shafaq-06 than Uqab-2000 under water deficit regimes was found to be associated
    with ALA improved leaf fluorescence (qN, NPQ and Fv/Fm), shoot and root K+, root Ca2+, proline and GB accumulation.
    Matched MeSH terms: Potassium
  4. Fulltext A New and All-Solid-State Potentiometric Aluminium Ion Sensor for Water Analysis
    Ying KS, Heng LY, Hassan NI, Hasbullah SA
    Sensors (Basel), 2020 Dec 03;20(23).
    PMID: 33287113 DOI: 10.3390/s20236898
    An all-solid-state potentiometric electrode system for aluminium ion determination was developed with a new aluminium ion sensor as the working electrode based on a new ionophore for aluminium ion, 1,1'-[(methylazanediyl)bis(ethane-2,1-diyl)]bis[3-(naphthalen-1-yl)thiourea] (ACH). The reference electrode was a potassium ion sensor, which acts as a pseudo-reference. Both electrodes were made from Ag/AgCl screen-print electrodes fabricated from a non-plasticized and photocurable poly(n-butyl acrylate) membrane that contained various other membrane components. The pseudo-reference potential based on the potassium ion sensor was fixed in 0.050 M KNO3, and such concentration of K+ ion did not interfere with the measurement of the Al3+ ion using the aluminium sensor. With such a pseudo-reference and in the presence of 0.050 M KNO3 as a background medium, the aluminium sensor measured changes of aluminium ion concentrations linearly from 10-6 to 10-2 M Al3+ ion with a Nernstian response of 17.70 ± 0.13 mV/decade. A low detection limit of 2.45 × 10-7 M was achieved with this all-solid-state potentiometric system. The aluminium sensor was insensitive to pH effects from 2.0 to 8.0 with a response time of less than 50 s. Under optimum conditions, a lifetime of 49 days was achieved with good sensor selectivity, reversibility, repeatability, and reproducibility. The all-solid-state electrode system was applied to analyze the Al3+ ion content of water samples from a water treatment plant. Compared with the conventional potentiometric detection system for aluminium ions, the new all-solid-state aluminium ion sensor incorporating a pseudo-reference from the potassium sensor demonstrated similar analytical performance. It thus provided a convenient means of aluminium content analysis in water treatment plants.
    Matched MeSH terms: Potassium
  5. A Patient with Hypokalemia and Hypoxemia-What Is the Culprit?
    Lai YY, Lim CH, Nazli MS, Samsudin IN, Thambiah SC
    Clin Chem, 2023 Nov 02;69(11):1220-1225.
    PMID: 37932109 DOI: 10.1093/clinchem/hvad158
    Matched MeSH terms: Potassium
  6. A STUDY OF NATURAL RADIOACTIVITY IN SOME BUILDING MATERIALS IN NIGERIA
    Maxwell O, Emmanuel JS, Olusegun AO, Cyril EO, Ifeanyi AT, Embong Z
    Radiat Prot Dosimetry, 2019 May 01;183(3):332-335.
    PMID: 30085254 DOI: 10.1093/rpd/ncy121
    Building materials of different brands were assessed for the concentrations of 226Ra, 232Th and 40K using HPGe detector. The activity concentrations in the measured samples ranged from 27 ± 8 to 82 ± 8 Bq kg-1 for 226Ra, 41 ± 4 to 101 ± 8 Bq kg-1 for 232Th and 140 ± 8 to 940 ± 19 Bq kg-1 for 40K, respectively. The Radium equivalent (Raeq) activity from the samples was found to be <370 Bq kg-1 as the recommended value for construction materials. This study will set a baseline data for significant standards on radiation exposure of the measured radionuclides in the selected building materials used in Nigeria.
    Matched MeSH terms: Potassium Radioisotopes/analysis*
  7. Fulltext A balanced randomised placebo controlled blinded phase IIa multi-centre study to investigate the efficacy and safety of AUT00063 versus placebo in subjective tinnitus: The QUIET-1 trial
    Hall DA, Ray J, Watson J, Sharman A, Hutchison J, Harris P, et al.
    Hear Res, 2019 06;377:153-166.
    PMID: 30939361 DOI: 10.1016/j.heares.2019.03.018
    AUT00063 is an experimental new medicine that has been demonstrated to suppress spontaneous hyperactivity by modulating the action of voltage-gated potassium-channels in central auditory cortical neurons of a rodent model. This neurobiological property makes it a good candidate for treating the central component of subjective tinnitus but this has not yet been tested in humans. The main purpose of the QUIET-1 (QUest In Eliminating Tinnitus) trial was to examine the effect of AUT00063 on the severity of tinnitus symptoms in people with subjective tinnitus. The trial was a randomised, placebo-controlled, observer, physician and participant blinded multi-centre superiority trial with two parallel groups and a primary endpoint of functional impact on tinnitus 28 days after the first drug dosing day. The trial design overcame the scale and logistical challenges of delivering a scientifically robust, statistically powered multi-centre study for subjective tinnitus within the National Health Service in England. The trial was terminated early for futility. Overall, 212 participants consented across 18 sites with 91 participants randomised to groups using age, gender, tinnitus symptom severity and hearing status as minimisation factors. While the pharmacokinetic markers confirm the uptake of AUT00063 in the body, within the expected therapeutic range, with respect to clinical benefit findings indicated that AUT00063 was not effective in alleviating tinnitus symptoms (1.56 point change in Tinnitus Functional Index). In terms of clinical harms, results indicated that a daily dose of 800 mg capsules of AUT00063 taken for 28 days was safe and well tolerated. These findings provide significant advances in the drug development field for hearing sciences, but raise questions about the predictive validity of certain rodent models of noise-induced hearing loss and tinnitus, as least for the mechanism evaluated in the present study. Trial Registration: (EudraCT) 2014-002179-27; NCT02315508.
    Matched MeSH terms: Shaw Potassium Channels/drug effects*; Shaw Potassium Channels/metabolism
  8. A bleeding throat
    Tuang GJ, Liman ARUA, Ramasundram S
    Emerg Med J, 2020 Feb;37(2):72-101.
    PMID: 31980549 DOI: 10.1136/emermed-2019-209119
    Matched MeSH terms: Amoxicillin-Potassium Clavulanate Combination/therapeutic use
  9. Fulltext A comparison of efficacy and safety of potassium-competitive acid blocker and proton pump inhibitor in gastric acid-related diseases: A systematic review and meta-analysis
    Simadibrata DM, Syam AF, Lee YY
    J Gastroenterol Hepatol, 2022 Dec;37(12):2217-2228.
    PMID: 36181401 DOI: 10.1111/jgh.16017
    BACKGROUND AND AIM: Potassium-competitive acid blocker (PCAB) is a recent alternative to proton pump inhibitor (PPI) for potent acid suppression. The current systematic review and meta-analysis aimed to compare the efficacy and safety of PCAB versus PPI in treating gastric acid-related diseases.

    METHODS: We searched up to June 5, 2022, for randomized controlled trials of gastric acid-related diseases that included erosive esophagitis, symptomatic gastroesophageal reflux disease (GERD), peptic ulcers, and Helicobacter pylori infection. The pooled risk ratio (RR) was evaluated for the efficacy outcome and treatment-emergent adverse events (TEAEs) as the safety outcome. Sensitivity analyses were performed to test the robustness of the study findings.

    RESULTS: Of the 710 screened studies, 19 studies including 7023 participants were analyzed. The RRs for the healing of erosive esophagitis with Vonoprazan versus PPI were 1.09 (95% confidence interval [CI] 1.03-1.14), 1.03 (95% CI 1.00-1.07), and 1.02 (95% CI 1.00-1.05) in Weeks 2, 4, and 8, respectively. There were no differences in the improvement of GERD symptoms and healing of gastric and duodenal ulcers between PCAB and PPI. The pooled eradication rates of H. pylori were significantly higher in Vonoprazan versus PPI first-line treatment (RR 1.13; 95% CI 1.04-1.22). The overall RR of TEAEs with Vonoprazan versus PPI was 1.08 (95% CI 0.89-1.31). Overall, the risk of bias was low to some concerns. Furthermore, sensitivity analyses confirmed the robustness of the study's conclusion.

    CONCLUSION: Vonoprazan is superior to PPI in first-line H. pylori eradication and erosive esophagitis but non-inferior in other gastric acid-related diseases. Likewise, short-term safety is comparable in both treatment groups.

    Matched MeSH terms: Potassium
  10. Fulltext A cross-sectional analysis of the PURE study on minerals intake among Malaysian adult population with hypertension
    Mat Nasir N, Md Isa Z, Ismail NH, Ismail R, Mohd Tamil A, Jaafar MH, et al.
    Sci Rep, 2024 Apr 13;14(1):8590.
    PMID: 38615144 DOI: 10.1038/s41598-024-59206-0
    Hypertension (HPT) is the leading modifiable risk factor for cardiovascular diseases and premature death worldwide. Currently, attention is given to various dietary approaches with a special focus on the role of micronutrient intake in the regulation of blood pressure. This study aims to measure the dietary intake of selected minerals among Malaysian adults and its association with HPT. This cross-sectional study involved 10,031 participants from the Prospective Urban and Rural Epidemiological study conducted in Malaysia. Participants were grouped into HPT if they reported having been diagnosed with high blood pressure [average systolic blood pressure (SBP)/average diastolic blood pressure (DBP) ≥ 140/90 mm Hg]. A validated food frequency questionnaire (FFQ) was used to measure participants' habitual dietary intake. The dietary mineral intake of calcium, copper, iron, magnesium, manganese, phosphorus, potassium, sodium, and zinc was measured. The chi-square test was used to assess differences in socio-demographic factors between HPT and non-HPT groups, while the Mann-Whitney U test was used to assess differences in dietary mineral intake between the groups. The participants' average dietary intake of calcium, copper, iron, magnesium, manganese, phosphorus, potassium, selenium, sodium, and zinc was 591.0 mg/day, 3.8 mg/day, 27.1 mg/day, 32.4 mg/day, 0.4 mg/day, 1431.1 mg/day, 2.3 g/day, 27.1 µg/day, 4526.7 mg/day and 1.5 mg/day, respectively. The intake was significantly lower among those with HPT than those without HPT except for calcium and manganese. Continuous education and intervention should be focused on decreasing sodium intake and increasing potassium, magnesium, manganese, zinc, and calcium intake for the general Malaysian population, particularly for the HPT patients.
    Matched MeSH terms: Potassium
  11. A fatal case of primary melioidotic prostatic abscess: the peril of poor drug compliance
    Wahab AA, Norliyana N, Ding CH, Nurzam SCH, Salbiah N, Rao KR
    Trop Biomed, 2020 Sep 01;37(3):560-565.
    PMID: 33612771 DOI: 10.47665/tb.37.3.560
    Primary prostatic melioidosis is a rare presentation of melioidosis even in melioidosis endemic areas. We report a case of a 58-year-old man with underlying diabetes mellitus who presented with a 5-day history of high-grade fever associated with lower urinary tract symptoms. Suprapubic tenderness and tender prostatomegaly were noted on examination. An abdominal computed tomography (CT) scan confirmed the presence of a prostatic abscess. Both blood and prostatic pus cultures grew Burkholderia pseudomallei. He was initially started on intravenous ceftazidime, followed by an escalation to intravenous meropenem. He was discharged home with oral amoxicillin-clavulanate and doxycycline after completing 12 days of meropenem. Unfortunately, his compliance to oral antibiotic therapy was poor, and he succumbed to the disease.
    Matched MeSH terms: Amoxicillin-Potassium Clavulanate Combination
  12. A field and laboratory study of the responses of cytoprotection and osmoregulation to salinity stress in mosquitofish (Gambusia affinis)
    Tsai JW, Liew HJ, Jhang JJ, Hung SH, Meng PJ, Leu MY, et al.
    Fish Physiol Biochem, 2018 Apr;44(2):489-502.
    PMID: 29192359 DOI: 10.1007/s10695-017-0448-y
    The mosquitofish (Gambusia affinis) naturally inhabits freshwater (FW; 1-3‰) and seawater (SW; 28-33‰) ponds in constructed wetland. To explore the physiological status and molecular mechanisms for salinity adaptation of the mosquitofish, cytoprotective responses and osmoregulation were examined. In the field study, activation of protein quality control (PQC) mechanism through upregulation of the abundance of heat shock protein (HSP) 90 and 70 and ubiquitin-conjugated proteins was found in the mosquitofish gills from SW pond compared to the individuals of FW pond. The levels of aggregated proteins in mosquitofish gills had no significant difference between FW and SW ponds. Furthermore, the osmoregulatory responses revealed that the body fluid osmolality and muscle water contents of the mosquitofish from two ponds were maintained within a physiological range while branchial Na+/K+-ATPase (NKA) expression was higher in the individuals from SW than FW ponds. Subsequently, to further clarify whether the cellular stress responses and osmoregulation were mainly induced by hypertonicity, a laboratory salinity acclimation experiment was conducted. The results from the laboratory experiment were similar to the field study. Branchial PQC as well as NKA responses were induced by SW acclimation compared to FW-acclimated individuals. Taken together, induction of gill PQC and NKA responses implied that SW represents an osmotic stress for mosquitofish. Activation of PQC was suggested to provide an osmoprotection to prevent the accumulation of aggregated proteins. Moreover, an increase in branchial NKA responses for osmoregulatory adjustment was required for the physiological homeostasis of body fluid osmolality and muscle water content.
    Matched MeSH terms: Sodium-Potassium-Exchanging ATPase/genetics; Sodium-Potassium-Exchanging ATPase/metabolism*
  13. A lead(II) ion selective electrode via a metal complex of poly(hydroxamic acid)
    Anuar K, Hamdan S
    Talanta, 1992 Dec;39(12):1653-6.
    PMID: 18965586
    A new lead(II) electrode has been constructed with poly(hydroxamic acid) (PHXA) as the active material and silicone rubber as the supporting material. The electrode gave near Nerstian response over the concentration range 4 x 10(-5)-1 x 10(-2)M lead(II). The detection limit of the electrode is approximately 4 x 10(-6)M and the electrode works well in the pH range 4.5-6.0. The response time was 50-120 sec over the whole concentration range and the electrode has a working life of at least 4 weeks. Iron(III) severely poisoned the electrode membrane. Nickel(II) and mercury(II) gave very strong interference compared to copper(II), silver(I), cobalt(II), sodium(I), potassium(I), zinc(II) and cadmium(II) which gave some or little interference. Values determined with atomic absorption (AAS) and a commercial lead(II) electrode were in good agreement with those measured with the lead(II) electrode reported here.
    Matched MeSH terms: Potassium
  14. Fulltext A mimicry of melioidosis by Klebsiella ozaenae infection
    Ng TH, How SH, Kuan YC, Adzura, Aziz AA, Fauzi AR
    Malays J Pathol, 2009 Dec;31(2):147-50.
    PMID: 20514860 MyJurnal
    Klebsiella ozaenae is a Gram negative bacillus. It has been described as a colonizer of oral and nasopharyngeal mucosa and is a cause of atrophic rhinitis. Klebsiella ozaenae has seldom been isolated from serious infections. However, several reports have stated that Klebsiella ozaenae may cause invasive infections and even mortality. We report a 55-year-old man with Klebsiella ozaenae infection causing abscesses involving the right eye and left kidney and possibly also in the brain, lungs and prostate. The isolates were sensitive to ceftazidime, ciprofloxacin, chloramphenicol, gentamicin and sulfamethoxazole-trimethoprim but resistant to ampicillin. He responded well to 4 weeks of i.v. ceftazidime and i.v. amoxycillin-clavulanic acid. To our knowledge, such a multiorgan infection has not been reported previously for this organism.
    Matched MeSH terms: Amoxicillin-Potassium Clavulanate Combination/therapeutic use
  15. A packed bed membrane reactor for production of biodiesel using activated carbon supported catalyst
    Baroutian S, Aroua MK, Raman AA, Sulaiman NM
    Bioresour Technol, 2011 Jan;102(2):1095-102.
    PMID: 20888219 DOI: 10.1016/j.biortech.2010.08.076
    In this study, a novel continuous reactor has been developed to produce high quality methyl esters (biodiesel) from palm oil. A microporous TiO2/Al2O3 membrane was packed with potassium hydroxide catalyst supported on palm shell activated carbon. The central composite design (CCD) of response surface methodology (RSM) was employed to investigate the effects of reaction temperature, catalyst amount and cross flow circulation velocity on the production of biodiesel in the packed bed membrane reactor. The highest conversion of palm oil to biodiesel in the reactor was obtained at 70 °C employing 157.04 g catalyst per unit volume of the reactor and 0.21 cm/s cross flow circulation velocity. The physical and chemical properties of the produced biodiesel were determined and compared with the standard specifications. High quality palm oil biodiesel was produced by combination of heterogeneous alkali transesterification and separation processes in the packed bed membrane reactor.
    Matched MeSH terms: Potassium Compounds/chemistry
  16. Fulltext A pilot study to Assess Serum Potassium Levels and Haemolysis in Red Cell Units
    Nurimatussolehah Sarijan, Sabariah Md Noor, Tun Maizura Mohd Fathullah, Malina Osman, Zainina Seman
    Malaysian Journal of Medicine and Health Sciences, 2018;14(103):1-5.
    MyJurnal
    Percentage of haemolysis is widely used as a quality parameter to assess red blood cell viability in blood banking. In certain blood banks, serum potassium level is used due to the unavailability of the former test. The relationship between these two tests, however, is still unclear. The objective of this study is to determine the association between haemolysis measured using two different methods for quality control. Methods: A total of forty-four samples of packed red cell in citrate-phosphate-dextrose with optisol were randomly selected from donation drives. Nine millilitres of blood was collected weekly starting from day-2 of storage, followed by day-7, 14, 21, 28, 35 and 42 for assessment of red blood cell haemolysis by measuring serum potassium level and percentage of haemolysis.Results: These two parameters were correlated significantly with a positive moderate linear relationship on day 7, 21 and 28 with r = 0.393, 0.448 and 0.425, respectively and p-values less than 0.01. The linear regression analysis showed there was a significant regression equation which could be used to predict the serum potassium level from the percentage of haemolysis. Conclusion: There were significant increases in the percentage of haemolysis and serum potassium level in the packed red cell units with storage. The serum potassium level would be able to be predicted from the percentage of haemolysis using the regression equations on day 7, 21 and 28. The serum potassium measurement could be used as an alternative test to the percentage of haemolysis before issuing blood.
    Matched MeSH terms: Potassium
  17. Fulltext A rare case of Riamet induced prolonged corrected QT interval
    Neesha Sundramoorthy, Khaiteri R., Jer Ming Low, Chan Soon Thim Darren
    Malaysian Journal of Medicine and Health Sciences, 2019;15(106):70-70.
    MyJurnal
    Introduction: Artemether and lumefantrine was registered as Riamet in Switzerland in 1999 and is commonly used in Keningau Hospital for managing uncomplicated malaria. Riamet works at the food vacoule of the malarial parasite, where they interfere with the conversion of heme into haemozoin. Case description: We report a case of Riamet induced prolonged corrected QT interval (QTc) in a 37 year old gentleman admitted for severe malaria (hypotension) with normal QTc of 420msc on presentation. Upon starting Riamet, he developed bradycardia and ECG showed sinus bradycardia with prolonged QTc of 551msec and no arrythmias. Echocardiography showed no structural heart abnormalities. All electrolytes were within normal range. He was monitored in cardiac care unit with decision to complete 6 doses of Riamet. Patient was started on Dopamine infusion which maintained his blood pressure and heart rate within normal range. 5 days post Riamet completion, his heart rate improved and dopamine infusion was tapered off and QTc normalized to 407msc. Discussion: The most common mechanism of drugs causing QT inter-val prolongation is by blocking the human ether-à-go-go related gene (hERG) potassium channel. Blockage of the hEGR channel lengthens ventricular re-polarization and duration of ventricular action potential which is reflected in ECG as prolonged QT interval. In the in-vitro whole cell patch clamp study, lumefantrine and its metabolite desbu-tyl-lumefantrine showed a concentration-dependent inhibition of the hERG current. The period of QTc prolongation was 3.5 to 4 days after the last dose of the standard 6 dose regimen. Conclusion: Riamet induced prolonged QTc is a very rare complication. A baseline electrocardiography is therefore imminent for every patient prior to initiation of this medication to avoid cardiac arrythmias.
    Matched MeSH terms: Potassium Channels
  18. ASSESSMENT OF NATURAL RADIOACTIVITY IN MAIZE AND ESTIMATION OF CONCOMITANT DOSE TO NIGERIAN VIA INGESTION PATHWAY
    Yarima MH, Khandaker MU, Nadhiya A, Olatunji MA
    Radiat Prot Dosimetry, 2019 Oct 01;184(3-4):359-362.
    PMID: 31089715 DOI: 10.1093/rpd/ncz115
    Uranium, thorium and potassium are the most abundant naturally occurring radioactive materials (NORMs) found in soils and other environmental media including foodstuffs. Since the human exposures to NORMs is an unavoidable phenomenon, in such a way that they can easily find their way to human being via food chain, detailed knowledge on their presence in foodstuffs is necessary to assess the radiation dose to the population. Thus, the present study concerns the assessment of natural radioactivity in maize, a staple foodstuff for Nigerian, via HPGe gamma-ray spectrometry. Activity concentrations (Bq/kg) in the maize samples were found to be in the range of 6.1 ± 0.6-8.2 ± 1.3, 2.2 ± 0.4-5.1 ± 0.7 and 288 ± 16-401 ± 24 for 226Ra, 232Th and 40K, respectively. Measured data for 226Ra and 232Th show below the world average values of 67 Bq/kg and 82 Bq/kg, respectively, while the activity of 40K exceeds the global average of 310 Bq/kg. The annual effective dose via the maize consumption was found to be far below the UNSCEAR recommended ingestion dose limit of 290 μSv/y, and the estimated lifetime cancer risk show lower than the ICRP (1991) cancer risk factor of 2.5 × 10-3 based on the additional annual dose limit of 1 mSv for general public, thus pose no adverse health risk to the Nigerian populace.
    Matched MeSH terms: Potassium Radioisotopes/analysis*
  19. ASSESSMENT OF NATURALLY OCCURRING RADIONUCLIDES IN MALAYSIA'S BUILDING MATERIALS
    Abdullahi S, Ismail AF, Samat S
    Radiat Prot Dosimetry, 2019 Dec 31;186(4):520-523.
    PMID: 31034551 DOI: 10.1093/rpd/ncz125
    The activity concentrations of 226Ra, 232Th and 40K radionuclides from common building materials used by Malaysian people for construction purposes were studied using High-Purity Germanium (HPGe) detector. The measured activity concentrations of the aforementioned radionuclides range from 10 ± 1 Bq kg-1 (limestone) to 155 ± 61 Bq kg-1 (feldspar), 12 ± 3 Bq kg-1 (limestone) to 274 ± 8 Bq kg-1 (kaolin) and 62 ± 19 Bq kg-1 (limestone) to 1114 ± 20 Bq kg-1 (pottery stone) for 226Ra, 232Th and 40K, respectively. The measured activity concentrations of the natural radionuclides reported herein were found to be in accordance with other previous studies. In general, the activity concentration of the natural radionuclides revealed that all the determined values were below the recommended limit.
    Matched MeSH terms: Potassium Radioisotopes/analysis*
  20. Fulltext Acrylated palm oil nanoparticle synthesized by radiation-induced process as a controlled drug delivery system
    Rida Tajau, Siti Farhana Fathy, Mek Zah Salleh, Nor Azowa Ibrahim, Maznah Ismail, Kamaruddin Hashim
    Jurnal Sains Nuklear Malaysia, 2013;25(2):20-29.
    MyJurnal
    The acrylated palm oil (APO) nanoparticle is a potential product that can be used as carriers in
    medical field. The main focus of the present study was to study the potential of the APO
    nanoparticles for used in a controlled drug delivery system. The microemulsion system is used as a
    medium to incorporate an active substance such as Thymoquinone (TQ) into the APO polymeric
    micelle and then the radiation technique is used as a tool for the synthesis of TQ-loaded APO
    nanoparticle. The nano-size TQ-loaded APO particles resulted the particle size of less than 150 nm
    with spherical in shape. The TQ release profile was carried out in potassium buffer saline (PBS)
    solutions (pH 7.4) at 37
    oC. And, the zero-order model has been used to determine the mechanism
    of the drug release from the corresponding nanoparticles, respectively. The TQ release was found
    to be sustained and controlled in pH 7.4. At pH 7.4, the release of TQ followed the zero-order
    model. The in-vitro drug release study showed a good prospect of the APO nanoparticle on being a
    potential drug carrier as there are toxic against colon cancer cells and not toxic towards normal
    cells. This suggested that the APO product produce using this radiation technique can be
    developed into different type of carrier systems for controlled drug release applications.
    Matched MeSH terms: Potassium
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