Displaying publications 1 - 20 of 450 in total

Abstract:
Sort:
  1. Ancyronyx lianlabangorum sp. nov., a new spider riffle beetle from Sarawak, and new distribution records for A. pulcherrimus Kodada, Jäch & Čiampor based on DNA barcodes (Coleoptera, Elmidae)
    Kodada J, Jäch MA, Freitag H, Čiamporová-Zaťovičová Z, Goffová K, Selnekovič D, et al.
    Zookeys, 2020;1003:31-55.
    PMID: 33384561 DOI: 10.3897/zookeys.1003.55541
    Ancyronyx lianlabangorumsp. nov. (Coleoptera, Elmidae), a new spider riffle beetle from the Kelabit Highlands (Sarawak, northern Borneo), is described. Illustrations of the habitus and diagnostic characters of the new species and the similar, polymorphic A. pulcherrimus Kodada et al. are presented. Differences to closely related species, based on COI nucleotide sequences and morphological characters, are discussed. Ancyronyx pulcherrimus is here recorded from Sarawak for the first time, based on DNA barcoding.
    Matched MeSH terms: Research Design
  2. Twenty-six new species of Hoploscopa (Lepidoptera, Crambidae) from South-East Asia revealed by morphology and DNA barcoding
    Léger T, Kehlmaier C, Vairappan CS, Nuss M
    Zookeys, 2020;907:1-99.
    PMID: 32063727 DOI: 10.3897/zookeys.907.36563
    Hoploscopa Meyrick (Lepidoptera: Crambidae) is a fern-feeding genus found in montane areas of South-East Asia and Melanesia, eastwards up to the Samoan Islands. It includes sixteen described species, with at least 70 further undescribed species known from scientific collections. An iterative approach including morphological and molecular characters was used in order to explore the diversity of Hoploscopa. The hitherto described species are revised, and descriptions authored by T. Léger and M. Nuss are provided for an additional 26 new species: H. agtuuganonensissp. nov., H. albipunctasp. nov., H. albomaculatasp. nov., H. anacanthasp. nov., H. boletasp. nov., H. cynodontasp. nov., H. danaoensissp. nov., H. gombongisp. nov., H. gracilissp. nov., H. ignitamaculaesp. nov., H. isarogensissp. nov., H. jubatasp. nov., H. kelamasp. nov., H. kinabaluensissp. nov., H. mallyisp. nov., H. marijoweissaesp. nov., H. matheaesp. nov., H. niveofasciasp. nov., H. pangrangoensissp. nov., H. parvimaculasp. nov., H. pseudometacrossasp. nov., H. sepanggisp. nov., H. sumatrensissp. nov., H. titikasp. nov., H. tonsepisp. nov., H. ypsilonsp. nov. Using a protocol specific for the amplification of DNA from old museum specimens, we recovered 101 COI barcodes for all but one of the newly described species, with 76 being barcode compliant (>487 bp). Species delimitation analyses suggest cryptic diversity, with six cases reflecting allopatric divergence, and two further cases found in sympatry.
    Matched MeSH terms: Research Design
  3. Fulltext Cube polygon: a new modified Euler method to improve electric circuit efficiency
    Nurhafizah Moziyana Mohd Yusop, Nooraida Samsudin, Nooraida Samsudin, Anis Shahida Mokhta, Siti Rohaidah Ahmad, Mohd Fahmi Mohammad Amran, et al.
    ZULFAQAR International Journal of Defence Science, Engineering & Technology, 2020;3(1):8-14.
    MyJurnal
    Euler method is a numerical order process for solving problems with the Ordinary Differential Equation (ODE). It is a fast and easy way. While Euler offers a simple procedure for solving ODEs, problems such as complexity, processing time and accuracy have driven others to use more sophisticated methods. Improvements to the Euler method have attracted much attention resulting in numerous modified Euler methods. This paper proposes Cube Polygon, a modified Euler method with improved accuracy and complexity. In order to demonstrate the accuracy and easy implementation of the proposed method, several examples are presented. Cube Polygon’s performance was compared to Polygon’s scheme and evaluated against exact solutions using SCILAB. Results indicate that not only Cube Polygon has produced solutions that are close to identical solutions for small step sizes, but also for higher step sizes, thus generating more accurate results and decrease complexity. Also known in this paper is the general of the RL circuit due to the ODE problem.
    Matched MeSH terms: Research Design
  4. Fulltext Application of ultra-high frequency antenna for partial discharge detection in oil-filled power transformer: a review
    Azharudin Mukhtaruddin, Muzamir Isa, Mohd Fadzil Ain, Mazlee Mohd Noor, Mohd Rafi Adzman, Mohamad Nur Khairul Hafizi Rohani
    ZULFAQAR International Journal of Defence Science, Engineering & Technology, 2020;3(2):1-17.
    MyJurnal
    Partial discharge (PD) is a phenomenon that may lead to dielectric breakdown and can provide important information for condition monitoring on electrical power equipment, in particular transformer. One of the methods is the detection of the electromagnetic (EM) wave signal emitted by PD. Although the frequency spectrum in EM is very wide, this paper discusses the detection of EM only at ultra-high frequency (UHF). One of the detectors that can be used to detect EM is the antenna. There are a lot of antenna designs that have been proposed to detect the signal. The designs can be generally divided into two: PCB-based design and physical antenna design. An example of the latter is monopole. Some of the proposed antennas were left at the design stage while others went to be applied in actual PD experimentation. Discussion on the capabilities of these antennas can lead to the selection of a suitable antenna.
    Matched MeSH terms: Research Design
  5. Fulltext Path finding of static indoor mobile robot via AOR iterative method using harmonic potentials
    A'qilah Ahmad Dahalan, Azali Saudi, Jumat Sulaiman
    ZULFAQAR International Journal of Defence Science, Engineering & Technology, 2020;3(2):18-24.
    MyJurnal
    Mobile robots often have to discover a path of collision-free towards a specific goal point in their environment. We are trying to resolve the mobile robot problem iteratively by means of numerical technique. It is built on a method of potential field that count on the use of Laplace’s equation in the mobile robot’s configuration space to constrain/which reduces the generation of a potential function over regions. This paper proposed an iterative approach in solving robot path finding problem known as Accelerated Over-Relaxation (AOR). The experiment shows that these suggested approach can establish a smooth path between the starting and goal points by engaging with a finite-difference technique. The simulation results also show that a more rapidly solution with smoother path than the previous work is achieved via this numerical approach.
    Matched MeSH terms: Research Design
  6. Trend of the research on construction and demolition waste management
    Yuan H, Shen L
    Waste Manag, 2011 Apr;31(4):670-9.
    PMID: 21169008 DOI: 10.1016/j.wasman.2010.10.030
    Research interests in addressing construction and demolition (C&D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C&D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibit an increasing research interest in C&D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C&D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C&D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C&D waste management research, and this is considered a major methodology for future research in the discipline. C&D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C&D waste management has emerged as a new challenging topic.
    Matched MeSH terms: Research Design*
  7. Drug utilization studies: their transferability between industrialized and developing countries
    Lee D, Balasubramaniam K, Ali HM
    WHO Reg Publ Eur Ser, 1993;45:193-218.
    PMID: 8442847
    Matched MeSH terms: Research Design
  8. Fulltext ISPOR Code of Ethics 2017 (4th Edition)
    Santos J, Palumbo F, Molsen-David E, Willke RJ, Binder L, Drummond M, et al.
    Value Health, 2017 12;20(10):1227-1242.
    PMID: 29241881 DOI: 10.1016/j.jval.2017.10.018
    As the leading health economics and outcomes research (HEOR) professional society, ISPOR has a responsibility to establish a uniform, harmonized international code for ethical conduct. ISPOR has updated its 2008 Code of Ethics to reflect the current research environment. This code addresses what is acceptable and unacceptable in research, from inception to the dissemination of its results. There are nine chapters: 1 - Introduction; 2 - Ethical Principles respect, beneficence and justice with reference to a non-exhaustive compilation of international, regional, and country-specific guidelines and standards; 3 - Scope HEOR definitions and how HEOR and the Code relate to other research fields; 4 - Research Design Considerations primary and secondary data related issues, e.g., participant recruitment, population and research setting, sample size/site selection, incentive/honorarium, administration databases, registration of retrospective observational studies and modeling studies; 5 - Data Considerations privacy and data protection, combining, verification and transparency of research data, scientific misconduct, etc.; 6 - Sponsorship and Relationships with Others (roles of researchers, sponsors, key opinion leaders and advisory board members, research participants and institutional review boards (IRBs) / independent ethics committees (IECs) approval and responsibilities); 7 - Patient Centricity and Patient Engagement new addition, with explanation and guidance; 8 - Publication and Dissemination; and 9 - Conclusion and Limitations.
    Matched MeSH terms: Research Design
  9. Initial, long-term, and durable responses to terazosin, placebo, or other therapies for chronic prostatitis/chronic pelvic pain syndrome
    Cheah PY, Liong ML, Yuen KH, Teh CL, Khor T, Yang JR, et al.
    Urology, 2004 Nov;64(5):881-6.
    PMID: 15533470 DOI: 10.1016/j.urology.2004.06.041
    OBJECTIVES: To evaluate the initial, long-term, and durable response rates to terazosin, placebo, or other therapies in patients with chronic prostatitis/chronic pelvic pain syndrome.
    METHODS: A total of 100 subjects, aged 20 to 50 years, who met the National Institutes of Health criteria for chronic prostatitis/chronic pelvic pain syndrome and had not previously been treated with alpha-blockers, were entered in a 14-week, double-blind comparison of terazosin or placebo therapy. Nonresponders and responders with subsequent relapse were treated with terazosin or other medications (open label). The criterion for response was a score of 0 to 2 on the National Institutes of Health Chronic Prostatitis Symptom Index quality-of-life item. The initial response was evaluated at week 14, and the long-term response was evaluated after a median of 38 weeks (range 34 to 42), regardless of any additional treatment. A durable response was defined as an initial response without additional treatment.
    RESULTS: Of the 43 patients in the terazosin group, 24 (56%) had an initial response compared with 14 (33%) of 43 subjects in the placebo group (P = 0.03). Long-term responses were noted in 23 (56%) of 41 assessable subjects treated with terazosin initially compared with 12 (32%) of 38 assessable subjects treated with placebo (P = 0.03). Of the nonresponders and initial responders with relapse, 7 (41%) of 17 subjects responded to terazosin compared with 7 (21%) of 34 given other treatment (P = 0.12). Durable responses occurred in 18 (44%) of the 41 assessable patients treated initially with terazosin and in 6 (16%) of 38 treated initially with placebo (P = 0.01).
    CONCLUSIONS: Patients treated with terazosin were more likely to have initial, long-term, and durable responses than those treated with placebo.
    Matched MeSH terms: Research Design
  10. Fulltext MENEROKA KESAN TEKANAN DAN SOKONGAN SOSIAL TERHADAP TANGGUNGJAWAB KEIBUBAPAAN DALAM KALANGAN BAPA TUNGGAL (Exploring Stress Impact and Social Support towards Parenting Responsibility among Single Fathers)
    Ainnur Erwana Saharudin, Khadijah Alavi
    UMT Journal of Undergraduate Research, 2019;1(4):105-114.
    MyJurnal
    Bapa tunggal merupakan satu golongan yang kurang dititikberatkan oleh masyarakat termasuk agensi-agensi dan NGO yang memfokuskan kepada kebajikan masyarakat berbanding dengan ibu tunggal. Hal ini kerana kebanyakan masyarakat merasakan bahawa golongan ini memiliki kekuatan fizikal dan mental yang tinggi memandangkan bapa tunggal adalah kaum lelaki. Namun, tidak dinafikan bahawa golongan bapa tunggal ini juga mengalami tekanan serius kerana kehilangan satu semangat atau sokongan tanpa pasangan hidupnya. Mereka terpaksa menyandang pelbagai tugas dalam rumah tangga dan membesarkan anak-anak. Kajian terdahulu lebih memfokuskan kepada ibu tunggal yang mendapat sokongan sosial daripada pelbagai agensi. Maka tekanan dan sokongan sosial penting dalam permasalahan bapa tunggal terutama dalam pengurusan rumah tangga dan pekerjaan harian. Objektif utama kajian ini ialah meneroka tekanan dan sokongan sosial dalam kalangan bapa tunggal. Kajian ini dijalankan dengan menggunakan pendekatan kualitatif berpandukan kajian kes. Teknik pengumpulan data kajian adalah melalui temu bual berstruktur. Tujuh orang informan telah dipilih bagi kajian ini dengan menggunakan teknik persampelan bertujuan (purposive sampling). Lokasi kajian yang dipilih ialah daerah Kuala Selangor, Selangor. Data temu bual berstruktur dianalisis secara tematik dan hasil kajian mendapati terdapat tiga faktor utama yang mempengaruhi tekanan terhadap bapa tunggal iaitu emosi, pengurusan rumah tangga dan pekerjaan yang ditemukan menerusi transkrip informan kajian. Manakala sokongan sosial yang diperlukan oleh golongan bapa tunggal ialah kewangan, sokongan moral dan tempat bersembang. Implikasi kajian ini diharapkan dapat mencadangkan program advokasi yang sesuai kepada pekerja sosial dalam mengendalikan kes bapa tunggal dalam komuniti dan institusi.
    Matched MeSH terms: Research Design
  11. Fulltext IMPACT OF MANAGEMENT POLICY ON DIRECT DRIVERS OF DEFORESTRATION IN MALAYSIA
    MOE SHWE SIN, SHANGKARI A/P WASU DAVEN
    UMT Journal of Undergraduate Research, 2020;2(2):67-82.
    MyJurnal
    Deforestation is one of the incredible difficulties confronting mankind. The extraction of woods remains one of the main drivers of deforestation in Malaysia. Relatively, rising in timber values may lead to enlarge in the net advantages of clearing land. Thus, this study is written to assess the process and underlying causes of forest cover change in Malaysia from 1997 to 2016. After assessed the discusses it on the impact of direct drivers with different management scenarios on deforestation in Malaysia. The research design, data, and method also performed by using System Simulation Model. Model validation and sensitivity tests was carried out after the simulation model is implemented to check the correctness in line with the real system. The simulation analysis was carried out with three different simulation periods together with the impact of two main policies: (1) controlling threshold profit; (2) discounted rate. The result of the study indicates that the most suitable policy combination to manage the deforestation is scenario 2 (policy 2B) with the RM650 per/ha threshold profit coupled with interest rate r=4% within 50years period.
    Matched MeSH terms: Research Design
  12. Fulltext CABARAN PEKERJA SOSIAL DALAM MENGENDALIKAN PENGURUSAN KES PENDERAAN KANAK-KANAK DI TASKA
    NANTHINI RAMALINGAM, KHADIJAH ALAVI
    UMT Journal of Undergraduate Research, 2021;3(1):99-100.
    MyJurnal
    Peningkatan kes penderaan kanak-kanak sehingga kematian kanak-kanak amat membimbangkan keluarga dan masyarakat. Artikel ini akan membahaskan tentang cabaran pekerja sosial dalam melindungi penderaan kanak-kanak di taska. Kajian lepas amat kurang mengkaji isu penderaan kanak-kanak di taska. Kajian ini dijalankan dengan menggunakan pendekatan kualitatif berpandukan kajian fenomenologi. Teknik pengumpulan data kajian melalui temubual berstruktur secara bertulis. 6 orang informan terdiri daripada pekerja sosial telah dipilih bagi kajian ini dengan menggunakan teknik persampelan bertujuan (purposive sampling). Lokasi kajian yang dipilih ialah taska sekitar Bandar Baru Bangi. Data temubual berstruktur dianalisis secara tematik dan hasil kajian mendapati terdapat tiga cabaran utama iaitu pertama praktis kerja sosial, konflik profesion dan kemahiran dalam mengendalikan pengurusan kes penderaan kanak-kanak. Implikasi kajian ini mencadangkan program kaunseling individu dan kelompok kepada pekerja sosial dan penting meningkatkan latihan dalam kemahiran mengendalikan pengurusan kes penderaan kanak-kanak yang semakin kompleks dan kritikal di masa depan.
    Matched MeSH terms: Research Design
  13. Fulltext ADAPTIVE TIME-STEPPING FOR RUNGE-KUTTA METHODS FOR ORDINARY DIFFERENTIAL EQUATIONS
    CHUA KAH WAI, LOY KAK CHOON, RUWAIDIAH IDRIS
    UMT Journal of Undergraduate Research, 2021;3(1):25-36.
    MyJurnal
    Ordinary Differential Equations (ODEs) are usually used in numerous fields especially in solving the modelling problem. Numerical methods are one of the vital mathematical tools to solve the ODEs that appear in various modelling problems by determining the approximation solution close to the in exact solution if it exists. Runge-Kutta methods (RK) are the numerical methods used to integrate the ODEs by applying multistage methods at the midpoint of an interval which can efficiently produce a more accurate result or small magnitude of error. We proposed Runge-Kutta methods (RK) to solve the 1st_ order nonlinear stiff ODEs. The RK methods used in this research are known as the RK-2, RK-4, and RK-5 methods. We proved the existence and uniqueness of the ODEs before we solved it numerically. We also proved the absolute-stability of the RK methods to determine the overall stability of these methods. We found two suitable test cases which are the standard test problem and manufactured solution. We proved that by combining the adaptive step size with RK methods can result in more efficient computation. We implemented the 2nd_, 4th_ and 5th_ order of RK methods with step size adaptively algorithm to solve the test problem and manufactured solution via Octave programming language. The resulting numerical error and the stability of each method can be studied. We compared our results using several error plots versus the Central Processing Unit (CPU) time required to compute a given nonlinear 1st_ order stiff ODE problem. In a conclusion, RK methods which combine with the adaptive step size can result in more efficient computation and accuracy compare with the fixed step size RK methods.
    Matched MeSH terms: Research Design
  14. Fulltext SENTIMENT ANALYSIS OF PEOPLE’S ACCEPTANCE TOWARDS THE NEW MALAYSIAN GOVERNMENT USING NAÏVE BAYES METHOD
    R.U GOBITHAASAN, NUR FARHANA SYAHIRA CHE HAMID
    UMT Journal of Undergraduate Research, 2020;2(3):93-102.
    MyJurnal
    Sentiment analysis is a field of research that has a significant impact on today’s nations, politics and businesses. It is an algorithmic process to comprehend the opinions of a given subject based on the Natural Language Processing (NLP) methodologies. It has received much attention in recent years and is proven vital in various fields, e.g., online product reviews and social media analysis (Twitter, Facebook, etc.). This paper reports the outcome of sentiment analysis to investigate people’s acceptance of Pakatan Harapan, as the new Malaysian government, spearheaded by Tun Dr. Mahathir Mohamad and Dr. Wan Azizah, with an influence of Dato Seri Anwar Ibrahim. The objective is to classify tweets into three types of sentiments; positive, neutral and negative using Naïve Bayes method which is readily available in Python. The first step is tweets extraction for a month (March to April 2019) using search queries: {Pakatan Harapan, Mahathir, Anwar Ibrahim, Wan Azizah}. It is followed by tweets wrangling using NLP library and lastly output visualization in the form of a word cloud. A word cloud is a visual representation of text data with various font sizes depending on its probabilities. Final results showed that the tweets related to new government consist of neutral sentiment (41%) followed by positive sentiment (30%) and negative sentiment (29%). Malaysians do prefer the new government. However careful mitigation steps must be crafted to overcome controversial issues such as the ‘Rome Statute’ to avoid negative digital footprint, hence winning the Malaysians’ heart.
    Matched MeSH terms: Research Design
  15. Fulltext THE EFFECT OF TRAWL BOARD PULL-OVER LOAD ON SUBSEA PIPELINE OF OFFSHORE SABAH
    MOHD ASLAN MOLENG, AHMAD FAIZAL AHMAD FUAD, MOHD HAFIZI SAID
    UMT Journal of Undergraduate Research, 2020;2(4):9-16.
    MyJurnal
    Trawling is a method of catching fish in a large volume where fish net is pulled through water using one or two boats. Bottom trawling is where the nets are pulled over or close to seabed and can affect the subsea pipeline if found along the route. Therefore, the objective of this study was to determine the impact of pull-over to selected subsea pipelines in Sabah and Labuan waters. This study involved four oil and gas pipelines in Sabah and Labuan waters from the oil fields to shore terminals. The research started with obtaining data of the pipelines and specification of trawl gear in Sabah. Fishing trawler traffic data along the pipelines route was determined by AIS system and site observation to determine the density of the trawlers. Trawl gear pull-over load was calculated using DNV algorithm and the inputs were trawl gear specification ^and fishing trawl speed. The severity was based on pull-over load calculated and pipeline yield stress. Then frequency was based on AIS data and density of fishing trawl per area. Based on the comparison between trawl pull-over load and yield strength/stress, the effect of trawl board pull-over is considered as minor, which is the lowest in the severity index.
    Matched MeSH terms: Research Design
  16. Fulltext GOLD PRICE FORECASTING USING BOX-JENKINS METHOD
    NUR ATIKAH KHALID, NURFADHLINA ABDUL HALIM
    UMT Journal of Undergraduate Research, 2019;1(3):15-27.
    MyJurnal
    In general, the nature of gold that acts as a hedge against inflation and its stable price over the course of the financial crisis has made it a unique commodity. Priceforecasts are a must for gold producers, investors and central bank to know the current trends in gold prices. Forecasting the future value of a variableis often done with time series analysis method. This study was conducted to determine the best model for forecasting gold commodity prices as well as forecasting world gold commodity prices in 2018 using Box-Jenkins approach. The data used in this study wasobtained from Investing.Com from 2015 until 2017. Thisstudy shows that ARIMA (1,1,1) is the best model to predict gold commodity prices based on Mean Absolute Percentage Error (MAPE). MAPE value for ARIMA (1,1,1) is 0.02%, where this value proves that forecasting using ARIMA (1,1,1) is the best forecasting becauseMAPE value is less than 10%.
    Matched MeSH terms: Research Design
  17. Fulltext ESTIMATION OF CORAL RUBBLE QUANTITY USING EDGE DETECTION AND MORPHOLOGICAL-BASED METHODS
    MUHAMMAD SUZURI HITAM, NURSYAHIRAH HAFIZ, ZAINUDDIN BACHOK, ZAINUDDIN BACHOK, MOHD SAFUAN CHE DIN
    UMT Journal of Undergraduate Research, 2019;1(3):105-119.
    MyJurnal
    Reef rubble representsthe broken components of the coraland reefstructure which could be in the form of dead,broken or other fragmented coral.The process to estimate the distribution of reef rubble is currently done manually and thus takesa long timeto completeand is laborious. This paper presentsan image-processing-basedmethod to estimate the distribution of reef rubbles in a coral reef environmentfrom a still image. The method is basically a series of image processing steps includingimage complement, image binarization, edgedetection, smoothing by Weiner filter and followed by erosion and dilation process.The experimentalresults showedthat the system wasable to roughly estimate the distribution of reef rubble.
    Matched MeSH terms: Research Design
  18. Fulltext ESTIMATION OF SAND DISTRIBUTION IN CORAL REEF ENVIRONMENT USING COLOURSEGMENTATION AND COLOURTHRESHOLDING METHODS
    PAULEEN ONG, MUHAMMAD SUZURI HITAM, ZAINUDDIN BACHOK, ZAINUDDIN BACHOK, MOHD SAFUAN CHE DIN
    UMT Journal of Undergraduate Research, 2019;1(3):96-104.
    MyJurnal
    At present, marine scientists employ manual method to estimate the components in coral reef environment,where Coral Point Count with Excel extensions (CPCe) software is used to determine the coral reef components and substrate coverage. This manual processis laboriousand time consuming,and needsexpertsto conduct the survey. In this paper, a prototype for estimating the distribution of sand cover in coral reef environment from still images by using colourextraction methods was introduced. The coloursegmentation called delta E was used to calculate the colourdifference between two coloursamples. Another method used wascolourthresholdby setting the range of sand colourpixels. Thesystem was developed by using a MATLAB software withimage processing toolbox. The developed system was semi-automatic computer-based system that can be used by researcherseven with little knowledge and experience to estimatethepercentage of sand coveragein coral reef still images.
    Matched MeSH terms: Research Design
  19. Fulltext Magnetic stimulation for stress urinary incontinence: study protocol for a randomized controlled trial
    Lim R, Liong ML, Leong WS, Khan NA, Yuen KH
    Trials, 2015;16:279.
    PMID: 26093910 DOI: 10.1186/s13063-015-0803-1
    There is currently a lack of randomized, sham-controlled trials that are adequately powered, using validated outcomes, to allow for firm recommendations on the use of magnetic stimulation for stress urinary incontinence. We report a protocol of a multicenter, randomized, double-blind, sham-controlled parallel-group trial to evaluate the efficacy of magnetic stimulation for stress urinary incontinence.
    Matched MeSH terms: Research Design
  20. Fulltext Statistical analysis plan for the 'Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage' (TICH-2) trial
    Flaherty K, Bath PM, Dineen R, Law Z, Scutt P, Pocock S, et al.
    Trials, 2017 Dec 20;18(1):607.
    PMID: 29262841 DOI: 10.1186/s13063-017-2341-5
    RATIONALE: Aside from blood pressure lowering, treatment options for intracerebral haemorrhage remain limited and a proportion of patients will undergo early haematoma expansion with resultant significant morbidity and mortality. Tranexamic acid (TXA), an anti-fibrinolytic drug, has been shown to significantly reduce mortality in patients, who are bleeding following trauma, when given rapidly. TICH-2 is testing whether TXA is effective at improving outcome in spontaneous intracerebral haemorrhage (SICH).

    METHODS AND DESIGN: TICH-2 is a pragmatic, phase III, prospective, double-blind, randomised placebo-controlled trial. Two thousand adult (aged ≥ 18 years) patients with an acute SICH, within 8 h of stroke onset, will be randomised to receive TXA or the placebo control. The primary outcome is ordinal shift of modified Rankin Scale score at day 90. Analyses will be performed using intention-to-treat.

    RESULTS: This paper and its attached appendices describe the statistical analysis plan (SAP) for the trial and were developed and published prior to database lock and unblinding to treatment allocation. The SAP includes details of analyses to be undertaken and unpopulated tables which will be reported in the primary and key secondary publications. The database will be locked in early 2018, ready for publication of the results later in the same year.

    DISCUSSION: The SAP details the analyses that will be done to avoid bias arising from prior knowledge of the study findings. The trial will determine whether TXA can improve outcome after SICH, which currently has no definitive therapy.

    TRIAL REGISTRATION: ISRCTN registry, ID: ISRCTN93732214 . Registered on 17 January 2013.

    Matched MeSH terms: Research Design
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links