Displaying publications 1 - 20 of 2915 in total

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  1. von Tunzelmann EW
    Matched MeSH terms: Temperature
  2. Darling ST
    J. Exp. Med., 1920 Aug 31;32(3):313-29.
    PMID: 19868447
    Three persons were experimentally inoculated with malaria by means of Anopheles ludlowi reared from larvae and infected with a pure strain of subtertian plasmodium (Plasmodium falciparum), thus proving that there exists no mechanical impediment or obstacle to the free exit of sporozoites from the salivary ducts or proboscis. In the dissection of infected mosquitoes there were no evidences of degenerated zygotes. Sporozoites appeared promptly in the salivary glands (9 to 12 days). Inoculation occurred with ease either in an interrupted feeding or after mosquitoes had been fed twice previously. The period of incubation was 14 and 18 days. The clinical manifestations were more severe in the subject that had never been infected with malaria previously, while the splenic enlargement was most pronounced in the subject infected after a long interval of freedom from malaria. In a third subject already suffering from tertian malaria there was only the slightest evidence of physical illness elicited by the superimposed subtertian infection; his temperature, however, became duly elevated. The type of febrile reaction in the two uncomplicated cases was at first tertian, becoming quotidian later, and this phenomenon in a pure strain leads strongly to the supposition that Plasmodium falciparum possesses inherently both tertian (or subtertian) and quotidian tendencies, as well as its well known tendencies to cause fever of the irregularly remittent or continued type. The creation of a specific plasmodium to account for clinical forms of aestivo-autumnal or subtertian malaria having a quotidian periodidty is probably unwarranted. In consideration of the facility with which this species can be infected and man inoculated experimentally, the occurrence of naturally infected wild specimens, and the positive epidemiological evidence, there should no longer exist in the minds of sanitarians any doubt as to its being a malarial carrier. Operations against this species can therefore be recommended without reservation and should be carried out without delay.
    Matched MeSH terms: Temperature
  3. Field JW, Niven JC
    Trans R Soc Trop Med Hyg, 1936;29:647-658.
    A comparison is made between atebrin-musonate and quinine bihydrochloride in the treatment of acute malaria. 286 cases of acute malaria due to Malayan strains of P. falciparum, P. vivax, and P. malariae, were treated in alternating sequence with one or other of these drugs. The rates at which the atebrin-musonate and the quinine case groups became trophozoite-free and fever-free are contrasted in a series of graphs. It is shown that there was a tendency for trophozoites to disappear from the peripheral blood and for temperatures to fall to normal somewhat earlier among cases treated with atebrin-musonate. No toxic effects of any importance were observed (but see footnote p. 657). Evidence is recorded which suggests that the minimal effective daily dose for an adult is 0·375 gramme (= atebrin 0·3 gramme). This dose when given either intramuscularly or intravenously on two successive days effected a rapid disappearance of parasites and fever. Intramuscular administration is regarded as the method of choice. It is noted that absorption of the drug from the muscles is very rapid, and that atebrin may be demonstrated in the urine within 10 minutes of an intramuscular injection of 0·3 gramme. A method of testing for the presence of atebrin in the urine which is sensitive to over one in a million is described. It was not possible to obtain precise data regarding the permanency of cure but an analysis of cases returning to hospital within 10 weeks of discharge suggests that relapses after atebrin-musonate treatment are probably fairly common.
    Matched MeSH terms: Temperature
  4. Iyer KG
    Med J Malaya, 1950;5.
    The viability of three recently isolated local strains of Bact. typhosus has been studied on 20 specimens of local hawker’s syrup used for sweetening ice balls and ice water. Precise survival times cannot be stated and only relatively wide limits can be estimated differing possibly in every individual case. Survival is influenced by the following factors : 1. The character of the containing material 2. The presence of other bacteria 3. Temperature 4. The presence of bactericidal agents or substances Significant diminution of the number of bacteria in 2 to 5 days after inoculation to sugar solutions is an important observation although survival up to two weeks has been noticed in repeated experiments. The results of experiments conducted in market syrup samples and on control experiments with laboratory sugar solutions indicate that the survival of the organisms tends to be more prolonged in dilute solutions than in concentrated
    Matched MeSH terms: Temperature
  5. Porter EG, Gibson Hill MMH
    Med J Malaya, 1951;5.
    1. Using ordinary clinical thermometers resting oral temperatures were taken in 4,463 schoolgirls between the ages of 6 and 20 years. 2. From 2,500 readings in clinically healthy and apyrexial girls charts were made to show temperature variations. 3. It was demonstrated that in the age group 6-10 the mean temperature was 99.5 F. That in the age group 10-14 the mean temperature was 99.3 F and in the age group 14-20 the mean temperature was 99.1 F. 4. For all age groups the majority fell within the limit of 98.9 – 100 F. 5. It is not uncommon to encounter a temperature of over 100º and up to 100.8º of no pathological significance. 6. Temperature readings are not a reliable guide in the clinical assessment of children unless the above considerations are borne in mind.
    Matched MeSH terms: Temperature
  6. YAP TIAN BENG
    Med J Malaya, 1956 Jun;10(4):326-31.
    PMID: 13399535
    Matched MeSH terms: Temperature*
  7. WHITTOW GC
    Med J Malaya, 1956 Dec;11(2):126-33.
    PMID: 13417936
    Matched MeSH terms: Hot Temperature*
  8. LIE-INJOLUAN EN, PILLAY RP
    Acta Haematol., 1964 May;31:282-8.
    PMID: 14172696
    Matched MeSH terms: Cold Temperature*
  9. Ghosh HK
    Med J Malaya, 1969 Mar;23(3):179-80.
    PMID: 4240070
    Matched MeSH terms: Hot Temperature*
  10. Paul FM, Kleevens JW
    J Singapore Paediatr Soc, 1969 Apr;11(1):62-6.
    PMID: 5366340
    Matched MeSH terms: Cold Temperature/adverse effects
  11. Perumal R, Bhattathiry EP
    Med J Malaya, 1970 Mar;24(3):208-11.
    PMID: 4246803
    Matched MeSH terms: Cold Temperature
  12. Chong YH, Ho GS
    Am J Clin Nutr, 1970 Mar;23(3):261-6.
    PMID: 5436634 DOI: 10.1093/ajcn/23.3.261
    Matched MeSH terms: Temperature
  13. Ghosh HK
    Med J Malaya, 1970 Jun;24(4):300-1.
    PMID: 4248352
    Matched MeSH terms: Hot Temperature
  14. Ong TH, Prathap K
    Aust N Z J Surg, 1970 Nov;40(2):186-90.
    PMID: 5275987
    Matched MeSH terms: Body Temperature
  15. Haisman MF
    Br J Nutr, 1972 Mar;27(2):375-81.
    PMID: 5015257
    Matched MeSH terms: Hot Temperature
  16. Chen PC
    Trop Geogr Med, 1973 Jun;25(2):197-204.
    PMID: 4717277
    Matched MeSH terms: Hot Temperature
  17. Gong NC, Rogers KJ
    Med J Malaysia, 1973 Jun;27(4):280-3.
    PMID: 4270786
    Matched MeSH terms: Body Temperature Regulation/drug effects*
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