Displaying publications 1 - 20 of 28 in total

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  1. Penilaian Kualiti Jasad Batuan di Terowong Kedua Genting Sempah, Selangor Darul Ehsan (Rock Mass Quality Evaluation of the Second Tunnel at Genting Sempah, Selangor Darul Ehsan)
    Abdul Ghani Rafek, Khairuddin Nordin
    Sains Malaysiana, 1997;26.
    The new Genting Sempah tunnel represents an important part of the widening and upgrading of the main east-west road link between Kuala Lumpur on the west coast and Kuantan on the east coast of Peninsular Malaysia. The new tunnel is located between 18m to 30m north of the existing (old) tunnel which was constructed in 1975 and has a similar alignment. Engineering geological investigations and site characterization for the construction of the new tunnel were carried out in 1994 with drilling, aerial photograph interpretation, surface geological mapping, geophysical surveys and laboratory testing. Rock mass classification was carried out based on the Q classification system of Barton et at. (1974). Based on this classification, it was predicted that for the tunnel zone, 8.6 % of the length of the tunnel consisted of rock mass classified as very poor i.e. type two, 82.8% as extremely poor, i.e. type three and the remaining 8.6% as exceptionally poor, i.e. type four. Excavation of the tunnel between March 1995 and September 1996 together with engineering geological logging and rock mass classification revealed the following; type two, very poor 6.3%, type three, extremely poor 89.9%, type four, exceptionally poor 3.8%. These results show the general validity of the prediction of the rock mass quality.
    Terowong kedua Genting Sempah merupakan suatu bahagian utama dalam pembesaran dan peningkatan taraf jalan timur-barat utama yang menghubungi Kuala Lumpur di pantai barat dan Kuantan di pantai timur Semenanjung Malaysia. Terowong kedua berkedudukan 18 m hingga 30 m ke utara terowong lama yang dibina pada tahun 1975 dan mempunyai penjajaran yang sama. Penyiasatan geologi kejuruteraan dan pemeriksaan tapak pembinaan terowong kedua dilaksanakan pada tahun 1994 dengan penggerudian, pentafsiran fotograf udara, pemetaan geologi permukaan, survei geofizik dan ujian makmal. Pengelasan kualiti jasad batuan dilakukan berdasarkan sistem pengelasan Q oleh Barton et al. (1974). Hasil pengelasan ini di zon terowong meramalkan 8.6% panjang terowong baru terdiri daripada jasad batuan berkualiti sangat rendah, iaitu jenis dua, 82.8% berkualiti tersangat rendah, iaitu jenis tiga manakala 8.6% panjang terowong terdiri daripada jasad batuan berkualiti luarbiasa rendah, iaitu jenis empat. Penggalian terowong di antara Mac 1995 dan September 1996 dengan rakaman geologi kejuruteraan dan pengelasan jasad batuan semasa penggalian menghasilkan keputusan seperti berikut; jenis dua, berkualiti sangat rendah 6.3%, jenis tiga, berkualiti tersangat rendah 89.9%, jenis empat, berkualiti luar biasa rendah 3.8%. Keputusan
    Matched MeSH terms: Thiocarbamates
  2. Cytotoxicity of triphenyltin(IV) methyl- and ethylisopropyldithiocarbamate compounds in chronic myelogenus leukemia cell line (K-562)
    Awang N, Kamaludin NF, Hamid A, Mokhtar NW, Rajab NF
    Pak J Biol Sci, 2012 Sep 01;15(17):833-8.
    PMID: 24163967
    Studies on the discovery of new cancer treatment by using metal-based compounds such as tin (Sn) has now greatly being synthesized and evaluated to identify their effectiveness and suitability to be developed as a new anticancer drug.

    APPROACH: This study was carried out to evaluate the cytotoxicity of triphenyltin(lV) methylisopropyldithiocarbamate (compound 1) and triphenyltin(IV) ethylisopropyldithiocarbamate (compound (2) on chronic myelogenus leukemia cells. The determination of their cytotoxicity (IC50) at different time of exposure and concentration was carried out through the employment of 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay.

    RESULTS: The IC50 values obtained for compound 1 and 2 following treatment at 24, 48 and 72 h were 0.660, 0.223, 0.370 microM and 0.677, 0.306, 0.360 microM, respectively. Cell morphological changes such as apoptotic and necrotic features were also been observed.

    CONCLUSION: The compounds tested were found to give cytotoxic effect against chronic myelogenus leukemia (K-562) cell at a micromolar dose. Thus, further study on their specific mechanism of actions in the human cells should be carried out to elucidate their potential as an anticancer agent.

    Matched MeSH terms: Thiocarbamates/pharmacology*
  3. Fulltext Chronic gamma irradiation for crops improvement and agrobiotechnology
    Azhar Mohamad
    Buletin Persatuan Genetik Malaysia, 2011;18(1):31-32.
    MyJurnal
    The Gamma Green House (GGH) is a chronic irradiation facility located at MINT Tech Park, Nuclear Malaysia, Jalan Dengkil. GGH is used for induction of mutation in plants and other biological samples with low dose radiation over period of time depending on the nature and sensitivity of the plant species. Gamma Greenhouse facility at Malaysian Nuclear Agency comprises an open topped
    irradiation area consisting of circular green house with 30 meters radius, control room and irradiator with interlock system. The irradiation source is a REVISS RSL6050 double encapsulated 800 Ci 137Cs (half-life 30.1 years for 137Cs) pencils and allowed to be exposed only when the entire 300 m diameter site is free from personnel. The irradiator system is secured by a sophisticated interlock system, which only allows the source to be exposed when all the prerequisite safety conditions are met, and automatically returns the source to the safe
    storage position if any safety device is compromised.
    Matched MeSH terms: Thiocarbamates
  4. Copper complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin induced apoptosis in breast cancer cell
    Foo JB, Low ML, Lim JH, Lor YZ, Zainol Abidin R, Eh Dam V, et al.
    Biometals, 2018 08;31(4):505-515.
    PMID: 29623473 DOI: 10.1007/s10534-018-0096-4
    Copper complexes have been widely studied for the anti-tumour application as cancer cells are reported to take up greater amounts of copper than normal cells. Preliminary study revealed that the newly synthesised copper complex [Cu(SBCM)2] displayed marked anti-proliferative towards triple-negative MDA-MB-231 breast cancer cells. Therefore, Cu(SBCM)2 has great potential to be developed as an agent for the management of breast cancer. The present study was carried out to investigate the mode of cell death induced by Cu(SBCM)2 towards MDA-MB-231 breast cancer cells. The inhibitory and morphological changes of MDA-MB-231 cells treated with Cu(SBCM)2 was determined by using MTT assay and inverted light microscope, respectively. The safety profile of Cu(SBCM)2 was also evaluated towards human dermal fibroblast (HDF) normal cells. Confirmation of apoptosis and cell cycle arrest were determined by flow cytometry analysis. The expression of p53, Bax, Bcl-2 and MMP2 protein were detected with western blot analysis. Cu(SBCM)2 significantly inhibited the growth of MDA-MB-231 cells in a dose-dependent manner with GI50 18.7 ± 3.06 µM. Indeed, Cu(SBCM)2 was less toxic towards HDF normal cells with GI50 31.8 ± 4.0 µM. Morphological study revealed that Cu(SBCM)2-treated MDA-MB-231 cells experienced cellular shrinkage, membrane blebbing, chromatin condensation and formation of apoptotic bodies, suggesting that Cu(SBCM)2 induced apoptosis in the cells, which was confirmed by Annexin-V/PI flow cytometry analysis. It was also found that Cu(SBCM)2 induced G2/M phase cell cycle arrest towards MDA-MB-231 cells. The induction of apoptosis and cell cycle arrest in the present study is possibly due to the down-regulation of the mutant p53 and MMP2 protein. In conclusion, Cu(SBCM)2 can be developed as a targeted therapy for the treatment of triple-negative breast cancer.
    Matched MeSH terms: Thiocarbamates/pharmacology; Thiocarbamates/chemistry
  5. Pencirian geomekanik jasad batuan dengan menggunakan kaedah seismos: nisbah poisson
    Goh T, Ghani Rafek A, Rahim Samsudin A, Hariri Ariffin M, Baizura Yunus N
    Sains Malaysiana, 2011;40:1123-1127.
    Parameter mekanik seperti nisbah Poisson merupakan parameter input kejuruteraan batuan terutamanya dalam perisian komputer model berangka. Kaedah seismos digunakan untuk menentukan nisbah Poisson jasad batuan segar (gred I), terluluhawa sedikit (gred II), terluluhawa sederhana (gred III) dan tinggi (gred IV). Nisbah Poisson setiap lapisan jasad batuan dikira berdasarkan nilai purata halaju gelombang mampatan (Vp) dan gelombang ricih (Vs) pada kedalaman tertentu. Halaju gelombang mampatan (Vp) diperoleh daripada survei seismos biasan dan halaju gelombang ricih (Vs) diperoleh daripada survei analisis spektral gelombang permukaan (SASW) atau analisis gelombang permukaan berbilang saluran (MASW). Sebanyak 66 ujian seismos telah dijalankan pada 9 cerun jasad batuan iaitu 6 ujian di atas 1 cerun jasad batuan granit di JKR kuari Bukit Penggorak, Kuantan, Pahang; 26 ujian di atas 4 cerun jasad batuan granit di Kuari Kajang Rock, Semenyih, Ulu Langat, Selangor; 12 ujian di atas 1 cerun jasad batuan granit di Lebuhraya Silk Kajang (km 14.6) Selangor; 14 ujian di atas 2 cerun jasad batuan syis di Jalan Kuala Kubu Baru-Bukit Fraser (km 15), Selangor dan 8 ujian di atas 1 cerun jasad batuan kuarzit di Section U10, Bukit Cherakah, Shah Alam, Selangor. Daripada ujian seismos, nilai maksimum nisbah Poisson jasad batuan yang bergred I, II, III dan IV ialah 0.295, 0.335, 0.355 dan 0.364. Nilai minimum nisbah Poisson jasad batuan yang mempunyai gred I, II, III dan IV ialah 0.215, 0.299, 0.334 dan 0.337. Nilai purata nisbah Poisson untuk jasad batuan bergred I, II, III dan IV ialah 0.274, 0.320, 0.345 dan 0.345. Nilai nisbah Poisson jasad batuan menjadi semakin besar apabila gred terluluhawa menjadi semakin besar. Nilai purata nisbah Poisson jasad batuan gred II, III dan IV bertambah sebanyak 16.8%, 25.9% dan 25.9% jika dibandingkan dengan jasad batuan gred I. Keadaan ini berlaku kerana perubahan retakan pada jasad batuan gred I adalah lebih besar apabila mengalami proses terluluhawa. Perubahan retakan menjadi semakin kecil apabila mengalami proses terluluhawa seterusnya. Tiada perubahan retakan berlaku pada jasad batuan gred III apabila menjadi jasad batuan gred IV.
    Matched MeSH terms: Thiocarbamates
  6. Two new monofunctional platinum(II) dithiocarbamate complexes: phenanthriplatin-type axial protection, equatorial-axial conformational isomerism, and anticancer and DNA binding studies
    Imran M, Rehman ZU, Hogarth G, Tocher DA, Chaudhry GE, Butler IS, et al.
    Dalton Trans, 2020 Nov 10;49(43):15385-15396.
    PMID: 33140800 DOI: 10.1039/d0dt03018j
    The syntheses of two platinum(ii) dithiocarbamate complexes (1 and 2) that show quinoplatin- and phenanthriplatin-type axial protection of the Pt-plane are described. The Pt-plane of complex 2 is axially more protected than that of complex 1. Furthermore, both complexes adopt two different stereochemical conformations in the solid state (based on single-crystal X-ray structures) owing to the structurally flexible piperazine backbone; i.e., C-e,e-Anti (1) and C-e,a-Syn (2), where "C" stands for the chair configuration, "e" and "a" stand for the equatorial and axial positions and "Anti" (opposite side) and "Syn" (same side) represent the relative orientations in space of the terminal substituents on the piperazine ring. In complex 2, the C-e,a-Syn conformation may provide additional steric hindrance to the Pt-plane. Despite the lower lipophilicity of 2 as compared to that of 1, the in vitro anticancer action against selected cancer cell lines is better for the former revealing the superior role of the axial protection over lipophilicity in modulating anticancer activity. The activity against the cancer promoting protein NF-κB signifies that the mode of cancer cell death may be the result of hindering the activity of NF-κB in the initiation of apoptosis. The apoptotic mode of cell death has been established earlier in a study using Annexin V-FITC. Finally, DNA binding studies revealed that the complex-DNA adduct formation is spontaneous and the mode of interaction is non-intercalative (electrostatic/covalent).
    Matched MeSH terms: Thiocarbamates/chemistry*
  7. Agrobacterium tumefaciens mediated transformation of the proteolysis 6 (prt6) gene into cotyledons of tomato cv. Micro tom
    Intan Elya Suka, Nur Farhana Roslan, Zamri Zainal, Nurulhikma Md Isa, Bee LC
    Sains Malaysiana, 2018;47:1465-1471.
    Gen Proteolisis 6 (PRT6) merupakan gen yang memainkan peranan penting dalam tapak jalan N-end rule dan berfungsi
    sebagai enzim E3 ligase. PRT6 berperanan dalam pengenalan protein sasaran bagi proses degradasi. Objektif utama kajian
    ini adalah untuk mentransformasi konstruk RNAi PRT6 ke dalam tomato berperantarakan Agrobacterium tumefaciens.
    Ini bertujuan untuk memahami peranan tapak jalan N-end rule semasa proses pemasakan buah. Beberapa faktor yang
    memberi kesan kepada transformasi seperti masa ko-penanaman dan juga kepekatan antibiotik yang digunakan telah
    dioptimumkan. Keputusan kajian menunjukkan pengeraman kotiledon selama 48 jam pada medium ko-penanaman dapat
    meningkatkan penghasilan kalus sebanyak 61% manakala penggunaan 500 mg/L antibiotik karbenisilin dalam medium
    regenerasi pucuk dapat mengurangkan kontaminasi A. tumefaciens sehingga 5.2%. Selain itu, strain A. tumefaciens
    C58 merupakan strain A. tumefaciens yang paling sesuai digunakan sebagai perantara dalam kajian ini. Tindak balas
    berantai polimerase (PCR) telah dijalankan pada pucuk yang terhasil untuk mengesahkan integrasi fragmen PRT6 ke dalam
    genom tomato. Berdasarkan analisis PCR, kesemua tujuh pucuk putatif transgenik adalah merupakan transforman positif.
    Matched MeSH terms: Thiocarbamates
  8. Pengenalpastian dan profil pengekspresan gen biosintesis asid amino yis psikrofil, glaciozyma antarctica
    Izwan Bharudin, Radziah Zolkefli, Shazilah Kamaruddin, Farah Diba Abu Bakar, Abdul Munir Abdul Murad, Mohd Faizal Abu Bakar, et al.
    Sains Malaysiana, 2018;47:1675-1684.
    Mekanisme pengambilan dan penghasilan asid amino bagi mikroorganisma psikrofil yang bermandiri dan berpoliferasi
    pada persekitaran sejuk melampau masih belum difahami sepenuhnya. Objektif kajian ini ialah untuk mengenal pasti
    gen yang terlibat dalam penjanaan asid amino bagi yis psikrofil, Glaciozyma antarctica serta menentukan pengekspresan
    gen tersebut semasa kehadiran dan kekurangan asid amino dalam medium pertumbuhan. Pengenalpastian gen telah
    dilakukan melalui penjanaan penanda jujukan terekspres (ESTs) daripada dua perpustakaan cDNA yang dibina daripada
    sel yang dikultur dalam medium pertumbuhan kompleks dan medium pertumbuhan minimum tanpa asid amino. Sebanyak
    3552 klon cDNA daripada setiap perpustakaan dipilih secara rawak untuk dijujuk menghasilkan 1492 transkrip unik
    (medium kompleks) dan 1928 transkrip unik (medium minimum). Analisis pemadanan telah mengenl pasti gen mengekod
    protein yang terlibat di dalam pengambilan asid amino bebas, biosintesis asid amino serta gen yang terlibat dengan
    kitar semula asid amino berdasarkan tapak jalan yang digunakan oleh yis model, Saccharomyces cerevisiae. Analisis
    pengekspresan gen menggunakan kaedah RT-qPCR menunjukkan pengekspresan gen mengekod protein yang terlibat di
    dalam pengambilan asid amino bebas iaitu permease adalah tinggi pada medium kompleks manakala pengekspresan
    kebanyakan gen mengekod protein yang terlibat dalam kitar semula dan biosintesis asid amino adalah tinggi di dalam
    medium minimum. Kesimpulannya, gen yang terlibat dalam penjanaan dan pengambilan asid amino bagi mikroorganisma
    psikrofil adalah terpulihara seperti mikroorganisma mesofil dan pengekspresan gen-gen ini adalah diaruh oleh kehadiran
    atau ketiadaan asid amino bebas pada persekitaran.
    Matched MeSH terms: Thiocarbamates
  9. Phosphanegold(I) dithiocarbamates, R3PAu[SC(=S)N((i)Pr)CH2CH2OH] for R = Ph, Cy and Et: role of phosphane-bound R substituents upon in vitro cytotoxicity against MCF-7R breast cancer cells and cell death pathways
    Jamaludin NS, Goh ZJ, Cheah YK, Ang KP, Sim JH, Khoo CH, et al.
    Eur J Med Chem, 2013 Sep;67:127-41.
    PMID: 23856069 DOI: 10.1016/j.ejmech.2013.06.038
    The synthesis and characterisation of R3PAu[S2CN((i)Pr)CH2CH2OH], for R = Ph (1), Cy (2) and Et (3)4, is reported. Compounds 1-3 are cytotoxic against the doxorubicin-resistant breast cancer cell line, MCF-7R, with 1 exhibiting greater potency and cytotoxicity than either of doxorubicin and cisplatin. Based on human apoptosis PCR-array analysis, caspase activities, DNA fragmentation, cell apoptotic assays, intracellular reactive oxygen species (ROS) measurements and human topoisomerase I inhibition, induction of apoptosis by 1, and necrosis by 2 and 3, are demonstrated, by both extrinsic and intrinsic pathways. Compound 1 activates the p53 gene, 2 activates only the p73 gene, whereas 3 activates both the p53 and p73 genes. Compounds 1 and 3 activate NF-κB, and each inhibits topoisomerase I.
    Matched MeSH terms: Thiocarbamates/chemistry*
  10. Synthesis, characterization and crystal structure of organotin(IV) N-butyl-N-phenyldithiocarbamate compounds and their cytotoxicity in human leukemia cell lines
    Kamaludin NF, Awang N, Baba I, Hamid A, Meng CK
    Pak J Biol Sci, 2013 Jan 01;16(1):12-21.
    PMID: 24199481
    Organotin complexes are recognized as the biologically active compounds in inducing cancerous cells death at very low doses. To date, organotin compounds currently appear among the most potent candidates in research related to the new anticancer drugs. In this study, new organotin(IV) N-butyl-N-phenyldithiocarbamate compounds have been successfully synthesized between the reaction of N-butylaniline amine with organotin(IV) chloride in 1:2/1:1 molar ratio. All compounds were characterized using the elemental analysis, FT-IR and NMR spectroscopy. The single crystal structure was determined by X-ray single crystal analysis. The elemental analysis showed good agreement with the suggested formula (C4H9)2Sn[S2CN(C4H9)(C6H5)]2 (Compound 1 and 2), (C6H5)2Sn[S2CN(C4H9)(C6H5)]2 (Compound 3) and (C6H5)3Sn[S2CN(C4H9)(C6H5)] (Compound 4). The important infrared absorbance peaks, v (C = N) and v(C = S) were detected in range between 1457-1489 cm(-1) and 951-996 cm(-1), respectively. The chemical shift of carbon in NCS2 group obtained from 13C NMR was found in range 198.86-203.53 ppm. The crystal structure of compound 4 showed that the dithiocarbamate ligand coordinates in a monodentate fashion. It crystallized in monoclinic P2(1)/n space group with the crystal cell parameter: a = 10.0488(1) angstroms, b = 18.0008(2) angstroms, c = 15.2054(2) angstroms, beta = 102.442(1) degrees and R = 0.044. The cytotoxicity (IC50) of these compounds against Jurkat E6.1 and K-562 leukemia cells were in the range between 0.4-0.8 and 1.8-5.3 microM, respectively as assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazholium bromide (MTT) assay. In conclusion, our study demonstrate that all compounds showed potent cytotoxicity towards both cell lines tested with the triphenyltin(IV) compound displayed the greatest effect.
    Matched MeSH terms: Thiocarbamates/chemical synthesis; Thiocarbamates/pharmacology*; Thiocarbamates/chemistry
  11. Taste-thresholds for phenylthiocarbamide of some population groups. II. The thresholds of two uncivilized ethnic groups living in Malaya
    LUGG JW
    Ann. Hum. Genet., 1957 Mar;21(3):244-53.
    PMID: 13411870
    Matched MeSH terms: Thiocarbamates*
  12. Taste thresholds for phenylthiocarbamide of some population groups. I The thresholds of some civilized ethnic groups living in Malaya
    LUGG JW, WHYTE JM
    Ann. Hum. Genet., 1955 Jun;19(4):290-311.
    PMID: 14388535
    Matched MeSH terms: Thiocarbamates*
  13. Fulltext Assessment of using tunneling and trenchless technology for constricting twin box culvert
    Mohammad, Thamer Ahmad, Mohd. Razali Abdul Kadir, Megat Johari Megat Mohd. Noor, Ahmad Husaini Sulaiman
    Pertanika Journal of Science & Technology, 2010;18(1):-.
    MyJurnal
    Part of the Seremban flood mitigation project in the state of Negeri Sembilan, Malaysia is to mitigate
    the flood at Jalan Rasah. The mitigation is planned to be implemented in packages. Package I and Package II of River Anak Air Rasah are parts of the project work. In these packages, wider and deeper concrete sections for the river are constructed. The existing undersized culverts were replaced by bigger reinforced concrete box culverts. The size of the box culverts was based on 100-years average reoccurrence interval (ARI). One of these culverts intersected with a rail line connecting Singapore and Malaysia. Trenchless jacking technique was used to lay the box culvert. The total length of the box culvert jacked under the railway line is 33 m, whereas the total width of the twin box culvert is 7.8 m with a total height of 3 m. This was the first time that the trenchless jacking techniques were used for the urban flood mitigation purpose in Malaysia, and it is mainly used to minimise traffic disruption. This study reports the success of using jacking technique in the development of the flood mitigation program of DID in Negeri Sembilan. Among other things, it explains significant performance of the technique under local conditions and experiences gained towards the advancement of tunnelling and trenchless technology.
    Matched MeSH terms: Thiocarbamates
  14. Fulltext Assessment of traffic noise and the association with non auditory effect among shop lot workers in Kajang, Selangor
    Mohd Zahiruddin Zukfali, Haliza Abdul Rahman
    Malaysian Journal of Public Health Medicine, 2016;16(10):0-0.
    MyJurnal
    The objective of study is to determine traffic noise level and non-auditory effect among shop lot workers at Kajang Selangor. This cross sectional study was carried to study traffic noise exposure with annoyance and work performance level among shop lot workers in Jalan Mendaling, JalanTukang and Jalan Sulaiman at Kajang town, Selangor. This study involves 120 shop lot workers that exposed to the traffic noise during their working hours where they are randomly selected. Noise exposure was estimated using the Sound Level Meter for environmental noise. The traffic volume was recorded using video recorder and calculated using tally counter. One set questionnaire consist standard questionnaire was used to assess the annoyance level and work performance level among the respondents. Respondents were predominantly by male which are 94 and female, 26 respondents. The mean age of the respondent were ranged between 41 to 60 years old. Only 12.5% of respondent are ranged 21 until 30 years old. In total of 120 respondent, 54.2% of them are Chinese while Malay and India only 30% and 15.8% respectively. The result showed that the traffic noise level at study areas are exceeded the permissible sound limit of commercial and business area during daylight which is 70 dB(A). Regarding work performance, 94 respondents are having low work performance level and 82% of respondent high annoyance level during the exposure of traffic noise from four different sources which are noise from the traffic, speeding vehicle, high traffic volume and exhaust system. There is a significant relationship between traffic noise level with work performance level (p=0.001) and annoyance level (p=0.026). The average traffic noise (Laeq) level at Jalan Mendaling, Jalan Tukang and Jalan Sulaiman is 71.19 dB(A) which were high and exceeds permissible sound level from road traffic, commercial and business place at day time, 70 dB(A). The exposure from the traffic noise effect the annoyance level and work performance level among the shop lot worker. In order to reduce traffic noise exposure towards the shop lot workers, some recommendation are needed to control the traffic noise such as build a noise barrier, plant trees and also enforcement of legal requirement in noise level.
    Matched MeSH terms: Thiocarbamates
  15. Fulltext Pembangunan wakaf pendidikan di University College Bestari, Terengganu
    Mutiara Dwi Sari, Ab. Aziz Yusof, Ahmad Shaifful Anuar Ahmad Shukor
    Malaysian Journal of Social Sciences and Humanities, 2016;1(4):1-17.
    MyJurnal
    Salah satu syarat untuk menjadi sebuah negara maju adalah tersedianya modal insan yang unggul yang
    lahir daripada Institusi Pengajian Tinggi. Kerajaan Malaysia telah memberikan peruntukan yang besar
    untuk mencapai matlamat tersebut. Walau bagaimanupun, terdapat kekangan dan keterhadan kewangan
    Kerajaan untuk memenuhi keseluruhan biaya Institusi Pengajian Tinggi. Oleh itu, semua pihak terkait
    perlulah mencari alternatif dan jalan keluar bagi mengatasi masalah ini. Wakaf merupakan salah satu
    sistem ekonomi Islam yang dikatakan sangat berpotensi bagi membangunkan pendidikan. Kertas kerja
    ini mempunyai dua tujuan. Pertama, untuk mengenal pasti pembangunan wakaf pendidikan dengan
    kajian kes di Universiti College Bestari (UCB), Terengganu, Malaysia. Kedua, menganalisis isu
    kelestaraian wakaf dan kaedah-kaedah yang digunakan UCB dalam mempastikan kelestarian wakaf
    tersebut. Bagi mencapai kedua-dua tujuan ini kaedah kualitatif yang melibatkan temu bual mendalam
    dua orang responden telah dijalankan. Data yang diperolehi di analisis menggunakan kaedah analisis
    kandungan. Hasil kajian mendapati bahawa pembangunan wakaf di UCB sudah bermula sejak tahun
    1998. Pengurusan dan pentadbiran wakaf UCB dilakukan di bawah tiga agensi (joint venture) yang
    setiapnya merupakan pemegang saham iaitu PEYATIM (Pertubuhan Kebajikan Anak Yatim Malaysia)
    (50%), PERKAYA (Pertubuhan Kebajikan Anak Yatim) Terengganu (30%) dan YAKIN (Yayasan
    Kebajikan Negeri Terengganu) (20%). Antara kaedah yang digunakan untuk melestarikan wakaf
    pengajian tinggi di UCB adalah penjagaan dan pengelolaan aset yang telus dengan kepimpinan yang
    kuat, sistem pemasaran dan kaedah wakaf yang mudah. Sumbangan kerajaan dan juga peranan alumni
    dikatakan juga membantu pembangunan wakaf tersebut. Kajian ini membuktikan bahawa sistem wakaf
    memiliki potensi untuk membantu membangunkan pendidikan yang lestari.
    Matched MeSH terms: Thiocarbamates
  16. Fulltext Satisfaction with amplification in daily life (SADL) in different types and degrees of hearing loss
    Nursakinah Abd Ghani, Wan Ahmad Wan Aslynn
    International Journal of Allied Health Sciences, 2019;3(4):933-938.
    MyJurnal
    Introduction: The aim of this study is to determine the satisfaction level of hearing aid users in different types and degrees of hearing loss using the satisfaction with amplification in daily life (SADL) questionnaire. Methods: 35 hearing aid users with different types of hearing loss who sought help from the International Islamic University, Malaysia (IIUM) Hearing and Speech Clinic at Jalan Hospital Campus, Kuantan, IIUM Medical Specialist Centre and private hearing aid centres were involved in this study. The data was collected from the participants who filled in the Malay SADL questionnaires. Results: Among the thirty-five (35) participants, there was no significant difference reported between the types of hearing loss and their satisfaction level in the SADL global score and each of the subscales. It was found that satisfaction level with the hearing aids may depend on several factors such as cosmetic preference, cost of hearing aid and audiologist competence. Meanwhile, in terms of degrees of hearing loss, 80% of the users were relatively satisfied with their hearing aids. Yet, there was no correlation between hearing aid users’ satisfaction level and their degrees of hearing loss for all subscales and SADL global score. Conclusions: This study indicates that although hearing aid users reported to be satisfied with their hearing aids; there are some who are not satisfied in terms of feedback, telephone use, cosmetic appearance and costs of hearing aid. The findings of this study can benefit the audiologists, as they would be able to use the information to help future patients understand and adapt to the use of the hearing aids better.
    Matched MeSH terms: Thiocarbamates
  17. Penilaian kualiti subgred turapan menggunakan kaedah analisis spektrum gelombang permukaan
    Rosyidi S, Taha M, Ismail A, Chik Z
    Sains Malaysiana, 2009;38.
    Dalam hal yang berkaitan dengan pengurusan turapan jalan raya, keupayaan galas lapisan subgred banyak mempengaruhi keadaan struktur turapan secara keseluruhan. Oleh itu, penilaian kualiti subgred diperlukan dari masa ke masa bagi mengawal kualiti turapan supaya ianya boleh dilalui kenderaan tanpa mengalami kerosakan. Kaedah Analisis Spektrum Gelombang Permukaan (lebih dikenali dengan Spectral Analysis of Surface Wave-SASW) merupakan suatu teknik uji kaji seismos tanpa musnah di lapangan yang boleh digunakan untuk penilaian kekukuhan dan kedalaman struktur turapan jalan termasuk lapisan subgred turapan dengan cepat dan menjimatkan. Makalah ini bertujuan untuk menunjukkan keupayaan kaedah SASW bagi menilai kualiti lapisan subgred turapan. Kaedah SASW dilakukan berdasarkan kaedah perambatan gelombang R. Berasaskan data beza fasa gelombang R yang merambat di permukaan turapan, lengkung eksperimen serakan halaju fasa diperolehi. Selanjutnya melalui proses songsangan, parameter dinamik bahan seperti halaju ricih yang mewakili modulus elastik dan ricih dinamik bahan turapan jalan boleh ditentukan. Hasil kajian menunjukkan bahawa kaedah SASW berupaya menghasilkan parameter dinamik bahan lapisan subgred turapan yang boleh diguna pakai. Beberapa model empirik dengan korelasi yang baik berjaya diterbitkan daripada kajian ini yang boleh digunakan dengan mudah di lapangan untuk penilaian kekukuhan lapisan subgred secara tepat.
    Matched MeSH terms: Thiocarbamates
  18. A simple method for chromium speciation analysis in contaminated water using APDC and a pre-heated glass tube followed by HPLC-PDA
    Salihu SO, Bakar NKA
    Talanta, 2018 May 01;181:401-409.
    PMID: 29426532 DOI: 10.1016/j.talanta.2018.01.041
    In this study, a simple sample preparation method was developed for the determination of tri-and hexavalent chromium in water samples. It utilizes a pre-heated customized glass tube (CGT), to supply the heat energy required for the reaction of Cr(III) with ammonium pyrrolidinedithiocarbamate (APDC). The products of the Cr complexes, tris(1-pyrrolidinecarbodithioato)chromium(III) and bis(1-pyrrolidinecarbodithioato)[1-pyrrolidinecarbodithio(thioperoxoato)]chromium(III) were chromatographed with Shimadzu LC-20AT and Zobax Eclipse C18 (150mm × 4.6mm, 5µm) column using ACN: Water, (7:3, v/v) as the mobile phase. The concentration of Cr(III) ranged from 0.06mgL-1to 0.09mgL-1and that of Cr(VI) was between 0.02mgL-1to 0.04mgL-1in the samples. Percentage recoveries from spiked real samples were between 87% (tap water) to 110% (wastewater) for Cr(III) and 92% (pond water) to 117% (tap water) for Cr(VI). The limits of detection (LODs) were 0.0029mgL-1and 0.0014mg/L-1for Cr(III) Cr(VI) respectively. While the limits of quantitation (LOQs), were 0.0098mgL-1and 0.0047mgL-1for Cr(III) and Cr(VI) respectively. Method precision (RSD (%)) was 3.3% and 3.5% for Cr(III) and Cr(VI) respectively. The developed method was applied for the speciation analysis of chromium in drinking water, tap water, wastewater, river water, and pond water samples. Our findings proved the method is simple and inexpensive. The method was validated by the analysis of a certified reference material (CRM) SLRS-4. The percentage recovery and RSD(%) from the spiked CRM were 91% and 115% and 0.32% and 1.4% for Cr(III) and Cr(VI) respectively.
    Matched MeSH terms: Thiocarbamates
  19. Pollution levels of thiobencarb, propanil, and pretilachlor in rice fields of the muda irrigation scheme, Kedah, Malaysia
    Sapari P, Ismail BS
    Environ Monit Assess, 2012 Oct;184(10):6347-56.
    PMID: 22089624 DOI: 10.1007/s10661-011-2424-9
    The purpose of this study was to investigate the potential risk of pretilachlor, thiobencarb, and propanil pollutants in the water system of the rice fields of the Muda area. The study included two areas that used different irrigation systems namely non-recycled (N-RCL) and recycled (RCL) water. Regular water sampling was carried out at the drainage canals during the weeding period from September to October 2006 in the main season of 2006/2007 and April-May 2007 in off season of 2007. The herbicides were extracted by the solid-phase extraction method and identified using a GC-ECD. Results showed that the procedure for identification of the three herbicides was acceptable based on the recovery test values, which ranged from 84.1% to 96.9%. A wide distribution pattern where more than 79% of the water samples contained the herbicide pollutants was observed at both the areas where N-RCL and RCL water was supplied for the two seasons. During September to October 2006, high weedicide residue concentration was observed at the N-RCL area and it ranged from 0.05 to 1.00 μg/L for pretilachlor and propanil and 10-25 μg/L for thiobencarb. In the case of the area with RCL water, the weedicide residue ranged from 1 to 5 μg/L for pretilachlor and propanil and 10-25 μg/L for thiobencarb. The highest residue level reached was 25-50, 50-100, and 100-200 μg/L for pretilachlor, propanil, and thiobencarb, respectively. During April to May 2007, high residue concentration frequently occurred at the area supplied with N-RCL irrigation water and it ranged from 0.05 to 1.00, 10 to 25, and 25 to 50 μg/L for pretilachlor, propanil, and thiobencarb, respectively. The highest residue level reached was 25-50 μg/L for pretilachlor and 100-200 μg/L for propanil and thiobencarb. There was an accelerated increase in the concentration of the herbicide residues, with the maximum levels reached at the early period of weedicide application, followed by a sharp decrease after the rice fields were completely covered with the rice crop. During the main season of 2006/2007, the concentration of propanil residue gradually rose, although that of the other herbicides declined.
    Matched MeSH terms: Thiocarbamates/analysis*
  20. Fulltext Penggunaan aplikasi GIS dalam penyakit tuberkulosis di Cheras, Kuala Lumpur, Malaysia
    Shamsul Azhar Shah, Md. Idris Mohd. Nor, Abdul Hadi Harman Shah, Tahir Aris
    Malaysian Journal of Public Health Medicine, 2002;2(2):15-26.
    MyJurnal
    Tuberkulosis merupakan penyakit yang masih meigadi masalah kesihatan di seluruh dunia amnya dan di Malaysia khasnya. Kajian telah dilakukan ali Cheras, Kuala Lumpur menggunakan aplikasi GIS untuk mengenalpasti taburan geografi dan tren tuberkulosis daripada tahun 1996 sehingga tahun 2000. Kajian ini juga dilakukan untuk melihat kebolehan GIS sebagai alat surveilan penyakit beyangkit. Hasil kajian dengan menggunakan aplikasi GIS mendapati tren peningkatan tuberkulosis di kawasan·kawasan yang tertentu di Cheras. Penumpuan kes-kes tuberkulosis dapat dilihat di kawasan taburan penduduk yang kepadatan tinggi dan sederhana tinggi terutama di kawasan Kampung Pandan, kawasan penempatan Jalan Cheras dan Bandar Tun Razak. Kes—kes tersebut juga kebanyakannya adalah dalam lingkungan 100 meter ke 200 meter di antara satu sama lain. Kesimpulannya secara am, aplikasi GIS memberikan dimensi baru dalam kawalan penyakit dan ia pasti dapat digunakan dalam membantu aktiviti surveilan penyakit tuberkulosis.
    Matched MeSH terms: Thiocarbamates
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