Displaying publications 1 - 20 of 547 in total

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  1. Qamar Z, Haji Abdul Rahim ZB, Neon GS, Chew HP, Zeeshan T
    Arch Oral Biol, 2019 Oct;106:104482.
    PMID: 31325718 DOI: 10.1016/j.archoralbio.2019.104482
    OBJECTIVE: The aim of the study was to determine demineralisation inhibition and remineralisation potential of poly-γ-glutamic acid with its possible mechanism of action on human dental enamel.

    METHODOLOGY: Three sodium-fluoride(NaF) concentration(0.01%w/v,0.1%w/v and 0.5%w/v respectively)and two poly-γ-glutamic acid(PGGA)concentration(1%w/v and 2%w/v respectively)were prepared in 0.1 M acetic acid(pH4.0)and deionized distilled water.For de/re-mineralisation study, tooth samples (18 teeth varnished, leaving a 2 mm2 window on the mid-buccal surfaces) were immersed in respective acidified NaF and PGGA solutions. The Ca2+ release/uptake was monitored with ISE over 72-hr with increasing pH every 24-h from 4.0 to 6.0.These teeth were later subjected to cross-sectional microhardness to determine integrated mineral recovery of enamel on increasing pH of respective acidified solution.In order to determine mechanism of PGGA,two concentrations of PGGA in deionized-water-solutions were used for tooth samples immersion followed by overnight drying then later subjected to Fourier Transform Infra-Red(FT-IR) analysis.The FT-IR analysis was also carried out on PGGA powder.For control,the experiment was repeated using hydroxyapatite(HAp)pellets.The density of PGGA solutions(1%and2%)was also measured to determine their dynamic viscosities.

    RESULTS: The ISE and microhardness testing revealed statistically significant (ρ ≤ 0.05) dissolution inhibition and remineralisation potential for tooth sample treated with acidified 2%PGGA. From the FT-IR spectra, it was observed that the profiles of the enamel and HAp surfaces treated with 1%-and 2%-PGGA solutions were similar to those of PGGA powder.It was found that the viscosity of PGGA increases with increasing concentration.

    CONCLUSION: The study implies that 2% PGGA is more effective than NaF as forms a coating layer to protect from demineralisation and promote remineralisation of the tooth surface.

    Matched MeSH terms: Tooth Remineralization*; Tooth Demineralization
  2. Aws Hashim Al-Kadhim, Normaliza AB Malik, Azlan Jaafar, Zainul Ahmad Rajion
    MyJurnal
    Introduction: A few studies investigated the numerous potential endodontic uses of CBCT, including the
    examination of root canal morphology and presumed that CBCT was effective for the initial identification of
    such morphology; moreover CBCT is a reliable method for the detection of the MB2 canal when compared
    with the gold standard of physical sectioning of the specimen. The aim of this study was to identify the root
    and canal morphology of the maxillary first molars among Malaysians analysed by cone-beam computed
    tomography (CBCT) images.

    Materials and Methods: Maxillary first (n = 421) molars from Malaysian patients
    (n = 241) of Malay, Chinese and Indians inceptions were examined by two Endodontists using in vivo CBCT
    methods. The number and configuration of roots, the number of root canals, and the canal configuration
    according to Vertucci’s classification were determined.

    Results: Single roots were not found in maxillary
    first molars. The incidence of fused roots was 1.995% in the first molars between mesiobuccal and
    distobuccal roots. In (421) 3-rooted maxillary first molars, additional canals were found in 45.6% of the
    mesiobuccal (MB) roots and 0% of the distobuccal (DB) roots. Bilateral symmetry of the MB roots was found
    in 82.36% of the first molar. Only one tooth was found to have pulp stone inside the pulp chamber.

    Conclusions: The root and canal configuration of a Malaysian population showed different features from
    those of other populations. CBCT scans can enhance the understanding of root canal anatomy, with the
    potential of improving the outcome of endodontic treatment.
    Matched MeSH terms: Tooth; Tooth Root
  3. Zainal Ariffin SH, Yamamoto Z, Zainol Abidin IZ, Megat Abdul Wahab R, Zainal Ariffin Z
    ScientificWorldJournal, 2011;11:1788-803.
    PMID: 22125437 DOI: 10.1100/2011/761768
    Tooth movement induced by orthodontic treatment can cause sequential reactions involving the periodontal tissue and alveolar bone, resulting in the release of numerous substances from the dental tissues and surrounding structures. To better understand the biological processes involved in orthodontic treatment, improve treatment, and reduce adverse side effects, several of these substances have been proposed as biomarkers. Potential biological markers can be collected from different tissue samples, and suitable sampling is important to accurately reflect biological processes. This paper covers the tissue changes that are involved during orthodontic tooth movement such as at compression region (involving osteoblasts), tension region (involving osteoclasts), dental root, and pulp tissues. Besides, the involvement of stem cells and their development towards osteoblasts and osteoclasts during orthodontic treatment have also been explained. Several possible biomarkers representing these biological changes during specific phenomenon, that is, bone remodelling (formation and resorption), inflammation, and root resorption have also been proposed. The knowledge of these biomarkers could be used in accelerating orthodontic treatment.
    Matched MeSH terms: Tooth Movement*
  4. Zainol Abidin IZ, Manogaran T, Abdul Wahab RM, Karsani SA, Yazid MD, Yazid F, et al.
    Curr Stem Cell Res Ther, 2023;18(3):417-428.
    PMID: 35762553 DOI: 10.2174/1574888X17666220627145424
    BACKGROUND: Proteomic is capable of elucidating complex biological systems through protein expression, function, and interaction under a particular condition.

    OBJECTIVE: This study aimed to determine the potential of ascorbic acid alone in inducing differentially expressed osteoblast-related proteins in dental stem cells via the liquid chromatography-mass spectrometry/ mass spectrometry (LC-MS/MS) approach.

    METHODS: The cells were isolated from deciduous (SHED) and permanent teeth (DPSC) and induced with 10 μg/mL of ascorbic acid. Bone mineralisation and osteoblast gene expression were determined using von Kossa staining and reverse transcriptase-polymerase chain reaction. The label-free protein samples were harvested on days 7 and 21, followed by protein identification and quantification using LC-MS/MS. Based on the similar protein expressed throughout treatment and controls for SHED and DPSC, overall biological processes followed by osteoblast-related protein abundance were determined using the PANTHER database. STRING database was performed to determine differentially expressed proteins as candidates for SHED and DPSC during osteoblast development.

    RESULTS: Both cells indicated brownish mineral stain and expression of osteoblast-related genes on day 21. Overall, a total of 700 proteins were similar among all treatments on days 7 and 21, with 482 proteins appearing in the PANTHER database. Osteoblast-related protein abundance indicated 31 and 14 proteins related to SHED and DPSC, respectively. Further analysis by the STRING database identified only 22 and 11 proteins from the respective group. Differential expressed analysis of similar proteins from these two groups revealed ACTN4 and ACTN1 as proteins involved in both SHED and DPSC. In addition, three (PSMD11/RPN11, PLS3, and CLIC1) and one (SYNCRIP) protein were differentially expressed specifically for SHED and DPSC, respectively.

    CONCLUSION: Proteome differential expression showed that ascorbic acid alone could induce osteoblastrelated proteins in SHED and DPSC and generate specific differentially expressed protein markers.

    Matched MeSH terms: Tooth, Deciduous*
  5. Majid ZA, Zain RB
    Singapore Dent J, 1988 Dec;13(1):44-6.
    PMID: 3155005
    A case of an incomplete tooth fracture followed by a complete fracture was presented. The difficulty of diagnosing this condition was discussed as well as the possible histological explanation of the symptoms experienced by the patient. It once again points out to practising dentists, that whilst deep pockets can give rise to severe periodontal pain, intense and excruciating pain should be investigated with the cracked tooth in mind.
    Matched MeSH terms: Cracked Tooth Syndrome*; Tooth Extraction
  6. Lim, Siau Peng, Fazal Reza, Zaihan Ariffin
    MyJurnal
    The purpose of this study was to evaluate hardness (indicator for polymerization) and thickness of two types of resin cement at coronal, middle and apical level of tooth root canal. Ten extracted maxillary incisors were instrumented and post space was prepared for cementation of titanium post. Samples were divided into two groups and each group was cemented either of the two types of resin cements; Panavia F [dual-cured (PF)] and Rely X Luting 2 [self-cured (RL)]. The teeth were longitudinally sectioned; hardness and thickness was measured using Vickers hardness tester and a microscope (Leica DMLM). SEM observations along the cement line at the 3 different root levels were performed. Statistical analysis was performed to test significance of differences in hardness and thickness of the two types of cement (t-test; p= 0.05) and at different levels of the same type (one-way ANOVA followed by multiple comparison; p= 0.05). Significant difference of hardness was found at the apical level between the two groups and between the coronal and apical level of PF (p0.05). Moreover, voids were more obvious within the dual-cured group of cement. Dual-cured resin cement was found to be less polymerized than self-cured type at apical level. Increased thicknesses of resin cements in comparison to post space size were observed in both groups. Use of metallic post with resin cements needs further evaluation.
    Matched MeSH terms: Tooth Root
  7. Chin WC, Zaidi Isa
    This research investigated the unit-root tests using nonparametric sequences-reversals (S-R), Phillip-Perron (PP) tests and parametric Augmented Dickey-Fuller (ADF) test for the Malaysian equity indices. Under the considerations of drift and structural break, it was found that during the restructuring period after the Asian financial crisis, most of the indices provided evidences against the unit-root tests. These results are somewhat contrasted with the conventional unit-root tests that ignored the impact of structural changes. In addition, the S-R tests were found to have little power to identify the deviations from the unit-root even after the inclusion of structural break.
    Matched MeSH terms: Tooth Root
  8. Yahya, A.N., Radzi, Z., Yusof, Z.Y.M.
    Malaysian Dental Journal, 2007;28(1):34-37.
    MyJurnal
    This clinical case report describes an aspect of restorative management of worn teeth. It illustrates the use of diagnostic overlay removable partial denture or DORPD, which has the same function as occlusal splint but with advantages of providing immediate aesthetic improvement and function.
    Matched MeSH terms: Tooth Attrition; Tooth Wear
  9. Esa R, Hashim NA, Ayob Y, Yusof ZY
    BMC Oral Health, 2015 Mar 10;15:28.
    PMID: 25886943 DOI: 10.1186/s12903-015-0013-y
    BACKGROUND: To evaluate the psychometric properties of the faces version of the Modified Child Dental Anxiety Scale (MCDASf) Malay version in 5-6 and 9-12 year-old children.
    METHODS: The MCDASf was cross culturally adapted from English into Malay. The Malay version was tested for reliability and validity in 3 studies. In the Study 1, to determine test-retest reliability of MCDASf scale, 166 preschool children aged 5-6 years were asked to rank orders five cartoons faces depicting emotions from 'very happy' to 'very sad' faces on two separate occasions 3 weeks apart. A total of 87 other 5-6 year-old children completed the Malay-MCDASf on two separate occasions 3 weeks apart to determine test-retest reliability for Study 2. In study 3, 239 schoolchildren aged 9-12 years completed the Malay-MCDASf and the Malay-Dental Subscale of the Children Fear Survey Schedule (CFSS-DS) at the same sitting to determine the criterion and construct validity.
    RESULTS: In study 1, Kendall W test showed a high degree of concordance in ranking the cartoon faces picture cards on each of the 2 occasions (time 1, W = 0.955 and time 2, W = 0.954). The Malay-MCDASf demonstrated moderate test-retest reliability (Intraclass correlation coefficient = 0.63, p <0.001) and acceptable internal consistency for all the 6 items (Cronbach's alpha = 0.77) and 8 items (Cronbach's alpha = 0.73). The highest MCDASf scores were observed for the items 'injection in the gum' and 'tooth taken out' for both age groups. The MCDASf significantly correlated with the CFSS-DS (Pearson r = 0.67, p < 0.001).
    CONCLUSIONS: These psychometric findings support for the inclusion of a cartoon faces rating scale to assess child dental anxiety and the Malay-MCDASf is a reliable and valid measure of dental anxiety in 5-12 year-old children.
    Matched MeSH terms: Tooth Extraction/psychology
  10. Yusof Z
    J Oral Rehabil, 1991 Jan;18(1):95-102.
    PMID: 2051253
    The aim of this study was to determine the periodontal status in relation to the quality of the adjacent proximal tooth surface. The gingival index (GI) and probable pocket depth (PD) were measured in 144 contra-lateral pairs of sound vs. restored and 95 contra-lateral pairs of sound vs. carious surfaces in 124 patients. The restorations studied were silver amalgams and tooth-coloured filling materials, the margins of which were supragingival or level with the gingival margins. The results showed that the GI and PD were greater for both restored and carious tooth surfaces than for the contra-lateral sound surfaces. When all the teeth were grouped together, the differences in the mean values of GI and PD were statistically significant at the P less than or equal to 0.05 level. A comparison between restored and carious (non-paired) tooth surfaces revealed higher mean values of GI and PD for the latter, which were highly significant at the P less than 0.001 level. Thus the present study shows that proximal tooth surface quality influences the health status of the adjacent periodontium.
    Matched MeSH terms: Tooth/pathology*
  11. Isa Z, Yusof Z
    J Oral Rehabil, 1990 Nov;17(6):541-50.
    PMID: 2283549
    The aims of this study were to determine the dental and periodontal status and the associated treatment needs, other than that for prosthetic care, in patients who requested removable partial dentures. Forty-six patients who had never worn removable partial dentures before were examined for plaque index, tooth status, gingival index, loss of periodontal attachment and tooth mobility. Prior to prosthetic treatment, 15% of the teeth needed conservative treatment and 1% needed extractions. From the periodontal point of view, 65% of the teeth needed some form of related therapy, and 2% of the teeth were at risk of extraction due to advanced mobility.
    Matched MeSH terms: Tooth Diseases/epidemiology*; Tooth Extraction; Tooth Mobility/epidemiology
  12. Yusof WZ
    J Can Dent Assoc, 1990 Feb;56(2):147-9.
    PMID: 2407326
    Multiple supernumerary teeth without any associated systemic conditions or syndromes are not common. The author reviewed most of the cases reported in the English-language literature from 1969 to the present. It was found that there was a predilection of non-syndrome multiple supernumerary teeth to occur in the mandible. When analyzed according to specific sites for both jaws, there was a predominance of the multiple supernumerary teeth to occur in the premolar area, followed by the molar and the anterior regions respectively. The mandibular premolar region had the highest frequency of occurrence for both jaws combined.
    Matched MeSH terms: Tooth, Supernumerary/pathology*
  13. Yusof NAM, Noor E, Reduwan NH, Yusof MYPM
    Clin Oral Investig, 2021 Mar;25(3):923-932.
    PMID: 32535703 DOI: 10.1007/s00784-020-03380-8
    OBJECTIVES: The aim of this study was to evaluate the accuracy of cone beam computed tomography (CBCT), periapical radiograph, and intrasurgical linear measurements in the assessment of molars with furcation defects.

    MATERIALS AND METHODS: This parallel, single-blinded, randomised controlled trial (RCT) consisted of 22 periodontitis patients who had molar with advanced furcation involvement (FI). All patients followed the same inclusion criteria and were treated following the same protocol, except for radiographic evaluation (CBCT vs. periapical). This study proposed and evaluated five parameters that represent the extent and severity of furcation defects in molars teeth, including CEJ-BD (clinical attachment loss), BL-H (depth), BL-V (height), RT (root trunk), and FW (width).

    RESULTS: There were no statistically significant differences between CBCT and intrasurgical linear measurements for any clinical parameter (p > 0.05). However, there were statistically significant differences in BL-V measurements (p 

    Matched MeSH terms: Tooth Cervix
  14. Wan Noor Rabiatul Akmalia Wan Abd Razak, Yushaini Ahmad
    MyJurnal
    Delayed tooth eruption (DTE) is the emergence of a tooth into oral cavity that
    deviates from norms established for different races, ethnics and sexes, which commonly caused
    either by local or systemic conditions. (Copied from article).
    Matched MeSH terms: Tooth; Tooth Abnormalities; Tooth Eruption
  15. Nurul Hasyiqin Fauzi, Widya Lestari, Azrul Fazwan Kharuddin, Yunita Dewi Ardini
    MyJurnal
    Non-syndromic tooth agenesis defined as developmental absence of more than one
    tooth that appears as independent congenital oral trait. Its prevalence, pattern and distribution
    rates vary by populations. The aim of this study was to identify the pattern and distribution of
    tooth agenesis in permanent dentition among IIUM dental polyclinic patients. (Copied from article).
    Matched MeSH terms: Tooth; Tooth Diseases
  16. Yahya, N.A., Youngson, C.C.
    Ann Dent, 2007;14(1):7-13.
    MyJurnal
    The purpose of this study were to compare the emergence profiles of crowns with their contralateral tooth, in vitro, and to determine if there is any association between the design of tooth preparations and the resultant emergence profile. 50 working models used for single crown construction were examined. Measurements of the faciolingual width of the crowns and contralateral teeth were taken using digital calipers. Internal line angles and the margin width of dies and the emergence profile of the corresponding crowns were measured from longitudinally sectioned polyvinylsiloxane indices mounted on a flat-bed scanner using image analysis software. Using Students t tests, no statistically significant differences (p>0.05) were found for shoulder width (mean 0.94 ± 0.23mm), internal line angle (mean 105.83 ± 13.57°) or emergence profiles (28.56 ± 12.95°) in the different (anterior, premolar or molar) preparations or crowns. The mean emergence profiles for all crowns was statistically significantly greater (p
    Matched MeSH terms: Tooth Preparation
  17. Sia S, Shibazaki T, Koga Y, Yoshida N
    Am J Orthod Dentofacial Orthop, 2009 Jan;135(1):36-41.
    PMID: 19121498 DOI: 10.1016/j.ajodo.2007.01.034
    This study was designed to determine the optimum vertical height of the retraction force on the power arm that is required for efficient anterior tooth retraction during space closure with sliding mechanics.
    Matched MeSH terms: Tooth Movement/instrumentation; Tooth Movement/methods*; Tooth Root/pathology; Tooth Crown/pathology
  18. Thong YL, Messer HH, Zain RB, Saw LH, Yoong LT
    Dent Traumatol, 2009 Aug;25(4):386-93.
    PMID: 19459923 DOI: 10.1111/j.1600-9657.2008.00631.x
    Progressive replacement resorption following delayed replantation of avulsed teeth has proved to be an intractable clinical problem. A wide variety of therapeutic approaches have failed to result in the predictable arrest of resorption, with a good long-term prognosis for tooth survival. Bisphosphonates are used in the medical management of a range of bone disorders and topically applied bisphosphonate has been reported to inhibit root resorption in dogs. This study evaluated the effectiveness of a bisphosphonate (etidronate disodium) as an intracanal medicament in the root canals of avulsed monkey teeth, placed before replantation after 1 h of extraoral dry storage. Incisors of six Macaca fascicularis monkeys were extracted and stored dry for 1 h. Teeth were then replanted after canal contamination with dental plaque (negative control) or after root canal debridement and placement of etidronate sealed in the canal space. A positive control of calcium hydroxide placed 8-9 days after replantation was also included. All monkeys were sacrificed 8 weeks later and block sections were prepared for histomorphometric assessment of root resorption and periodontal ligament status. Untreated teeth showed the greatest extent of root resorption (46% of the root surface), which was predominantly inflammatory in nature. Calcium hydroxide treated teeth showed the lowest overall level of resorption (<30% of the root surface), while the bisphosphonate-treated group was intermediate (39%). Ankylosis, defined as the extent of the root surface demonstrating direct bony union to both intact and resorbed root surface, was the lowest in the untreated control group (15% of the root surface), intermediate in the calcium hydroxide group (27%) and the highest in the bisphosphonate group (41%). Bony attachment to the tooth root was divided approximately equally between attachment to intact cementum and to previously resorbed dentin. Overall, bisphosphonate resulted in a worse outcome than calcium hydroxide in terms of both root resorption and ankylosis.
    Matched MeSH terms: Tooth Avulsion/therapy*; Tooth Replantation/methods*; Tooth Root/pathology; Tooth Ankylosis/pathology; Tooth Ankylosis/prevention & control
  19. Yip WK
    Oral Surg. Oral Med. Oral Pathol., 1974 Jul;38(1):80-7.
    PMID: 4525999
    Matched MeSH terms: Tooth Abnormalities/epidemiology*; Tooth Abnormalities/pathology
  20. Swathi B, Charitha M, Mandava D, Tugaram N, Mudrakola DP, Yelamanchi R
    J Int Soc Prev Community Dent, 2019 04 12;9(2):205-209.
    PMID: 31058072 DOI: 10.4103/jispcd.JISPCD_438_18
    Aim: This study aims to find out the proinflammatory chemokines macrophage inflammatory protein (MIP)-1α and MIP-1β levels in gingival crevicular fluid (GCF) of primary, mixed, and permanent dentitions.

    Materials and Methods: GCF of 160 individuals (4-15 years of age) was collected by the extracrevicular method. They were categorized into four groups (40 per each group). Group I: subjects with primary dentition (4-5 years of age), Group II: 40 subjects in early transition period (6-8 years), Group III: 40 individuals in the late transition period (9-11 years), and Group IV: 40 individuals with permanent dentition (12-15 years). MIP-lα and MIP-1β levels were determined in the samples of GCF by ELISA method. Data were analyzed by software SPSS Version 20 (IBM SPSS Statistics for Windows, IBM Corp., Armonk, NY: USA).

    Results: MIP-1α and MIP-1β were detected in all samples. The highest mean MIP-1α and MIP-1β concentrations in GCF were detected in the early transition period, while the lowest concentrations were seen in primary dentition group. The chemokine levels were higher in girls than in boys in Group III. There was a substantial rise of MIP-1α and MIP-1β levels during eruption.

    Conclusions: Since levels of MIP-1α and MIP-1β in GCF are positively associated with tooth eruption, they may perhaps be deemed as novel biomarkers in the eruption process.

    Matched MeSH terms: Tooth Eruption; Tooth, Deciduous
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