Displaying publications 1 - 20 of 56 in total

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  1. Dewi WN, Zhou Q, Mollah M, Yang S, Ilankoon IMSK, Chaffee A, et al.
    Waste Manag, 2024 Apr 30;179:99-109.
    PMID: 38471253 DOI: 10.1016/j.wasman.2024.03.007
    Fast co-pyrolysis offers a sustainable solution for upcycling polymer waste, including scrap tyre and plastics. Previous studies primarily focused on slow heating rates, neglecting synergistic mechanisms and sulphur transformation in co-pyrolysis with tyre. This research explored fast co-pyrolysis of scrap tyre with polypropylene (PP), low-density polyethylene (LDPE), and polystyrene (PS) to understand synergistic effects and sulphur transformation mechanisms. A pronounced synergy was observed between scrap tyre and plastics, with the nature of the synergy being plastic-type dependent. Remarkably, blending 75 wt% PS or LDPE with tyre effectively eliminated sulphur-bearing compounds in the liquid product. This reduction in sulphur content can substantially mitigate the release of hazardous materials into the environment, emphasizing the environmental significance of co-pyrolysis. The synergy between PP or LDPE and tyre amplified the production of lighter hydrocarbons, while PS's interaction led to the creation of monocyclic aromatics. These findings offer insights into the intricate chemistry of scrap tyre and plastic interactions and highlight the potential of co-pyrolysis in waste management. By converting potential pollutants into valuable products, this method can significantly reduce the release of hazardous materials into the environment.
    Matched MeSH terms: Hazardous Substances
  2. Ghaffari Khaligh N, Mihankhah T, Titinchi S, Shahnavaz Z, Rafie Johan M
    Turk J Chem, 2020;44(4):1100-1109.
    PMID: 33488215 DOI: 10.3906/kim-2005-6
    This work introduces a new additive named 4,4'-trimethylenedipiperidine for the practical and ecofriendly preparation of ethyl 5-amino-7-(4-phenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate derivatives. This chemical is commercially available and easy to handle. It also possesses a low melting point and a broad liquid range temperature, high thermal stability, and good solubility in water. Based on green chemistry principles, the reaction was performed in a) a mixture of green solvents i.e. water and ethanol (1:1 v/v) at reflux temperature, and b) the additive was liquefied at 65 °C and the reaction was conducted in the liquid state of the additive. High yields of the desired triazolo-pyrimidines were obtained under both aforementioned conditions. Our results demonstrated that this additive, containing 2 Lewis base sites and able to act as an acceptor-donor hydrogen bonding group, is a novel and efficient alternative to piperidine, owing to its unique properties such as its reduced toxicity, nonflammable nature, nonvolatile state, broad liquid range temperature, high thermal stability, and ability to be safely handled. Furthermore, this additive could be completely recovered and exhibited high recyclability without any change in its chemical structure and no significant reduction in its activity. The current methodology has several advantages: (a) it avoids the use of hazardous materials, as well as toxic, volatile, and flammable solvents, (b) it does not entail tedious processes, harsh conditions, and the multistep preparation of catalysts, (c) it uses a metal-free and noncorrosive catalyst, and (d) reduces the generation of hazardous waste and simple work-up processes. The most important result of this study is that 4,4'-trimethylenedipiperidine can be a promising alternative for toxic, volatile, and flammable base reagents in organic synthesis owing to its unique properties.
    Matched MeSH terms: Hazardous Substances
  3. Premalatha GD, Ravindran J
    Med J Malaysia, 2000 Mar;55(1):146-51; quiz 152.
    PMID: 11072503
    The number of women in the workforce in increasing. A substantial proportion are in the reproductive age which brings to attention the problem of work exposures that adversely affect reproductive outcome. These exposures include chemicals, radiation, strenuous physical activity and infections. They affect reproduction by effect on the germ cells, through hormonal distribution which in turn affects transport of germ cells or zygote, implantation and development. Some of these exposures are teratogenic. At present, some regulations and policies seem to be directed at women workers while there is evidence to show that women are not the only victims. Paternal exposures have also been reported to be associated with infertility, spontaneous abortions and other adverse outcomes. There is insufficient information about reproductive effects of work exposures and hence further research is required in this area.
    Matched MeSH terms: Hazardous Substances/adverse effects
  4. College of Pathologists, Academy of Medicine of, Malaysia
    Malays J Pathol, 2005 Jun;27(1):71-2.
    PMID: 16676698
    Matched MeSH terms: Hazardous Substances/standards*
  5. Tan CC
    Scand J Work Environ Health, 1991 Aug;17(4):221-30.
    PMID: 1925433
    Nurses are an integral component of the health care delivery system. In discharging their duties, nurses encounter a variety of occupational health problems which may be categorized into biological hazards, chemical hazards, physical hazards, and psychosocial hazards. A review of some examples of each of these four types of hazards is presented in this article. Particular attention has been devoted to hepatitis B, acquired immunodeficiency syndrome, tuberculosis, cytotoxic drugs, anesthetic agents, needlestick injury, back pain, and stress.
    Matched MeSH terms: Hazardous Substances/adverse effects
  6. Hutagalung SD, Kam CL, Darsono T
    Sains Malaysiana, 2014;43:267-272.
    Many techniques have been applied to fabricate nanostructures via top-down approach such as electron beam lithography. However, most of the techniques are very complicated and involves many process steps, high cost operation as well as the use of hazardous chemicals. Meanwhile, atomic force microscopy (AFM) lithography is a simple technique which is considered maskless and involves only an average cost and less complexity. In AFM lithography, the movement of a probe tip can be controlled to create nanoscale patterns on sample surface. For silicon nanowire (SiNW) fabrication, a conductive tip was operated in non-contact AFM mode to grow nanoscale oxide patterns on silicon-on-insulator (SOI) wafer surface based on local anodic oxidation (LAO) mechanism. The patterned structure was etched through two steps of wet etching processes. First, the TMAH was used as the etchant solution for Si removing. In the second step, diluted HF was used to remove oxide mask in order to produce a completed SiNW based devices. A SiNW based device which is formed by a nanowire channel, source and drain pads with lateral gate structures can be fabricated by well controlling the lithography process (applied tip voltage and writing speed) as well as the etching processes.
    Matched MeSH terms: Hazardous Substances
  7. Rampal KG, Mohd Nizam J
    Regul Toxicol Pharmacol, 2006 Nov;46(2):131-5.
    PMID: 16899331
    In Malaysia exposures in the workplace are regulated under the Factories and Machinery Act (FMA), 1967 and also under the more comprehensive Occupational Safety and Health Act (OSHA) enacted in 1994. With OSHA 1994 the philosophy of legislating safety and health in the workplace changed from one that was very prescriptive and containing detailed technical provisions under FMA, 1967 to one that is more flexible and encourages self-regulation under OSHA 1994. OSHA 1994 is supported by regulations, codes of practices and guidelines to further clarify the provisions in the Act. Under the FMA 1967 emphasis was on safety while with OSHA 1994 there has been equal emphasis on addressing health hazards in the workplace. Regulations for occupational exposures are developed by the Department of Occupational Safety and Health with tripartite and stakeholder consultation. When developing these regulations International Labor Organization Conventions, laws of other countries and occupational exposure standards adopted internationally are reviewed. The government also conducts surveys to collect information on both exposures and health effects in workplaces to have better understanding on specific occupational health problems. Effective law enforcement is crucial in ensuring compliance to safety and health law. The challenge at the moment is to ensure all employers and employees, particularly those in the small and medium enterprises, understand and comply with the provisions stipulated in the legislation.
    Matched MeSH terms: Hazardous Substances/analysis*
  8. Karami R, Mohsenifar A, Mesbah Namini SM, Kamelipour N, Rahmani-Cherati T, Roodbar Shojaei T, et al.
    PMID: 26503886
    Organophosphorus (OP) compounds are one of the most hazardous chemicals used as insecticides/pesticide in agricultural practices. A large variety of OP compounds are hydrolyzed by organophosphorus hydrolases (OPH; EC 3.1.8.1). Therefore, OPHs are among the most suitable candidates which could be used in designing enzyme-based sensors for detecting OP compounds. In the present work, a novel nanobiosensor for the detection of paraoxon was designed and fabricated. More specifically, OPH was covalently embedded onto chitosan and the enzyme-chitosan bioconjugate was then immobilized on negatively charged gold nanoparticles (AuNPs) electrostatically. The enzyme was immobilized on AuNPs without chitosan as well to compare the two systems in terms of detection limit and enzyme stability under different pH and temperature conditions. Coumarin 1, a competitive inhibitor of the enzyme, was used as a fluorogenic probe. The emission of coumarin 1 was effectively quenched by the immobilized Au-NPs when bound to the developed nanobioconjugates. However, in the presence of paraoxon, coumarin 1 left the nanobioconjugate leading to enhanced fluorescence intensity. Moreover, compared to the immobilized enzyme without chitosan, the chitosan-immobilized enzyme was found to possess decreased Km value by over 50%, increased Vmax and Kcat values by around 15% and 74%, respectively. Higher stability within a wider range of pH (2-12) and temperature (25-90°C) was also achieved. The method worked in the 0 to 1050 nM concentration ranges, and had a detection limit as low as 5 × 10(-11) M.
    Matched MeSH terms: Hazardous Substances
  9. Ho, C. L. I., Choo, B. Q.
    MyJurnal
    In this paper, stormwater runoff from a residential catchment located in Miri, Sarawak, was characterized to determine the pollutant concentrations and loading. The observed average event mean concentrations were 116 mg/L for TSS, 115 mg/L for COD, 1.5 mg/L for NH3-N, and 0.23 mg/L for Pb. Based on Interim National Water Quality Standards (INWQS) for Malaysia, the average event mean concentration, EMC value for TSS exceeded class II (50 mg/L), exceeded class V (>100 mg/L) for COD, and exceeded class III (0.9 mg/L) for NH3-N. All four water quality parameters exhibited first flush characteristic but to varying magnitude which was influenced by the storm characteristics.
    Matched MeSH terms: Hazardous Substances
  10. Arora H, Sharma A, Sharma S, Haron FF, Gafur A, Sayyed RZ, et al.
    Microorganisms, 2021 Apr 13;9(4).
    PMID: 33924471 DOI: 10.3390/microorganisms9040823
    Capsicum annuum L. is a significant horticulture crop known for its pungent varieties and used as a spice. The pungent character in the plant, known as capsaicinoid, has been discovered to have various health benefits. However, its production has been affected due to various exogenous stresses, including diseases caused by a soil-borne pathogen, Pythium spp. predominantly affecting the Capsicum plant in younger stages and causing damping-off, this pathogen can incite root rot in later plant growth stages. Due to the involvement of multiple Pythium spp. and their capability to disperse through various routes, their detection and diagnosis have become crucial. However, the quest for a point-of-care technology is still far from over. The use of an integrated approach with cultural and biological techniques for the management of Pythium spp. can be the best and most sustainable alternative to the traditionally used and hazardous chemical approach. The lack of race-specific resistance genes against Pythium spp. can be compensated with the candidate quantitative trait loci (QTL) genes in C. annuum L. This review will focus on the epidemiological factors playing a major role in disease spread, the currently available diagnostics in species identification, and the management strategies with a special emphasis on Pythium spp. causing damping-off and root rot in different cultivars of C. annuum L.
    Matched MeSH terms: Hazardous Substances
  11. Salvaraji L, Jeffree MS, Avoi R, Akhir HM, Rahim SSSA, Lukman KA
    Medeni Med J, 2020;35(4):304-309.
    PMID: 33717622 DOI: 10.5222/MMJ.2020.82246
    Objective: Increasing amount of waste concurrently increases the risk of exposure to hazardous materials among waste collectors. Vigorous exertion in the field intensifies the abundance of contaminated inspirable droplets. If left undetected and untreated, it may provoke significant pernicious health effects and redundant burdens to employees and employers. The purpose of this study is to determine the prevalence of respiratory symptoms and their associated factors among domestic waste collectors.

    Method: A cross-sectional study was conducted in Kota Kinabalu, Sabah between January and April 2020. Data were collected using a validated questionnaire which encompasses details about sociodemographic, health status, environment, and employment characteristics.

    Results: A total of 290 waste collectors with a mean age of 40 (±9) years old were participated in the study. Most of them were from Kadazan-Dusun-Murut ethnic origin with educational background till secondary school. The average monthly income of the workers was USD 298.45 (±171.9) per month, and they had been in service for 11 (±9.04) years. Respiratory symptoms were seen in 21% of the workers. The identified significant risk factors were determined as underlying chronic diseases (OR=2.34; 95% CI=1.054, 5.219) and contact with pets (OR=1.87; 95% CI=1.004, 3.288).

    Conclusion: Respiratory symptoms are prevalent amidst domestic waste collectors and related to their health and field activities.

    Matched MeSH terms: Hazardous Substances
  12. Lee HS, Park JH, Singh JK, Ismail MA
    Materials (Basel), 2016 Sep 03;9(9).
    PMID: 28773875 DOI: 10.3390/ma9090753
    Waste water treatment reservoirs are contaminated with many hazardous chemicals and acids. Reservoirs typically comprise concrete and reinforcement steel bars, and the main elements responsible for their deterioration are hazardous chemicals, acids, and ozone. Currently, a variety of techniques are being used to protect reservoirs from exposure to these elements. The most widely used techniques are stainless steel plating and polymeric coating. In this study, a technique known as arc thermal spraying was used. It is a more convenient and economical method for protecting both concrete and reinforcement steel bar from deterioration in waste water treatment reservoirs. In this study, 316L stainless steel coating was applied to a concrete surface, and different electrochemical experiments were performed to evaluate the performance of coatings in different acidic pH solutions. The coating generated from the arc thermal spraying process significantly protected the concrete surface from corrosion in acidic pH solutions, owing to the formation of a double layer capacitance-a mixture of Cr3+ enriched with Cr₂O₃ and Cr-hydroxide in inner and Fe3+ oxide on the outer layer of the coating. The formation of this passive film is defective owing to the non-homogeneous 316L stainless steel coating surface. In the pH 5 solution, the growth of a passive film is adequate due to the presence of un-dissociated water molecules in the aqueous sulfuric acid solution. The coated surface is sealed with alkyl epoxide, which acts as a barrier against the penetration of acidic solutions. This coating exhibits higher impedance values among the three studied acidic pH solutions.
    Matched MeSH terms: Hazardous Substances
  13. Hasni MJ
    MyJurnal
    Minamata disease is a well-known mercury contamination that happened in Japan in 1953. Due to demand during world war, second mercury disaster occurred in Niigata Prefecture in 1965. This is a review on the Niigata Minamata disease based on available documents and local expert opinions on the disaster. The aims of this paper are to record exposure history like the source of mercury in Agano River and specific fish that was associated with the disease. It is for an appraisal of the basic mercury exposure control, particularly to protect Japanese and world population during that time. There was indication that initial exposure limit for mercury was calculated incorrectly, and higher safe dose was applied. This epidemiological study is very useful and significant in comprehend the correct estimation of the human exposure to any hazardous substances.
    Matched MeSH terms: Hazardous Substances
  14. NurKhairlida Muhamad Khai, Khai EL, Mazlin Mokhta, Choo TG, Marlia Mohd Hanafiah, Chan PW, et al.
    Chemical industry is one of the important industries in the world. However, incidents happened due to the release of hazardous materials, toxic and poisonous chemicals in the chemical industries can cause fatal to human and destruction of the environment. Learning from the Bhopal disaster's experience, chemical industries have developed a program - Responsible Care, aiming to regain public trust through improving the environment, health and safety performances. Malaysia has adopted Responsible Care program since 1994 under the stewardship of the Chemical Industries Council of Malaysia (CICM). Six codes of management practices have been developed by the CICM, covering distribution, community awareness and emergency response, pollution prevention, process safety, employee health & safety and product stewardship. It has been more than 20 years since its inception. However, to date, there are only 125 companies have signed the pledge to adopt Responsible Care program. The CICM has also conducted several initiatives to encourage participation of chemical companies to adopt Responsible Care program in Malaysia. Therefore, it is the aim of this paper to review the current status of Responsible Care program in Malaysia and also deliberate the way forward of this program.
    Matched MeSH terms: Hazardous Substances
  15. Anuar, I., Zahedi, F., Kadir, A., Mokhtar, A.B.
    MyJurnal
    Background: The occupationally acquired accident and injuries in Malaysian medical laboratories are still largely unexplored prior to this survey. Some of these questions are attempted in this survey and act as source of reference for the number and accident injuries in medical laboratories in the area of Klang Valley and also in Malaysia.
    Methods : This survey was carried out based on recordable cases throughout the calendar year of 2001 to 2005 from 3 main medical laboratories of Hospital Kuala Lumpur (HKL), Hospital Universiti Kebangsaan Malaysia (HUKM) and Pusat Perubatan Universiti Malaya (PPUM).
    Results : The average annual incident rate for this three medical laboratories is 2.05/100 full time equivalent (FTE) employees. The annual incident rate in individual medical laboratory is 2.04/100 FTE (HKL), 2.07/100 FTE (HUKM) and 2.04/100 FTE (PPUM) employees, respectively. The most common injury that is 25.3% of the total cases reported was due to cuts by sharp objects and the second most common injury was exposure to biohazard and chemical substances which constitutes 19.9% of the total cases. . Needle prick injury (16.8%), fire (8.4%), fall/slip (6.3%) and gases leak and locked in cold room were reported as one case each.
    Conclusion : The average incident rate from this study is remarkably similar compared with the incident injury rate reported by BLS (2006) which is 2.1/100 FTE in the average size of medical laboratory and diagnostic. Besides this incident rate of injury and illness as a comparison, it also can be used as a benchmark to evaluate the safety performance among medical laboratories in Malaysia.
    Matched MeSH terms: Hazardous Substances
  16. Muhammad Firdaus Othman,, Nor Aimi Abdul Wahab, Suhaiza Hasan, Marina Mokhtar, Noorezal Atfyinna Mohd Napiah, Mohd Noor Mokhtar, et al.
    Jurnal Inovasi Malaysia, 2019;2(2):123-139.
    MyJurnal
    Teaching, learning and reseach activities in chemical laboratory usually involves a variety of hazardous chemicals. All chemicals stored in the laboratories should be accompanied by a safety data sheet which contains information such as chemical composition, safety precautions for handling and storing chemicals and emergency measures in case of accident. Ineffective management of chemical safety data sheet makes it difficult to access and resulting in slow action taken in the event of accident. To overcome this problem, Quisy-SDS was introduced to ensure a more effective chemical safety information management. Quisy-SDS provides a convenient method for all lab users and emergency respondents to acess the chemical safety information. This method uses a Quick Response (QR) code and website that allow users to acess the information in no time, anytime and anywhere. The use of Quisy-SDS has successfully reduced the search time of chemical safety information by 98% compared to the previous method.
    Matched MeSH terms: Hazardous Substances
  17. Salvaraji L, Jeffree MS, Avoi R, Atil A, Mohd Akhir H, Shamsudin SBB, et al.
    J Public Health Res, 2020 Oct 14;9(4):1994.
    PMID: 33312989 DOI: 10.4081/jphr.2020.1994
    An increasing amount of waste concurrently further extends the risk of exposure to hazardous material among waste collectors. In light of the COVID-19 crisis, municipal waste collectors are one of the most at-risk groups of SARS-Cov-2 exposure. Risk assessment included hazard identification, evaluation of existing control level at the workplace, estimation of likelihood and severity of hazard, risk determination, and control measure recommendations. Five waste collection activities were identified and reviewed. High-risk exposure includes collection of garbage, mechanical manipulation of compactor lorries and unloading of garbage at the disposal site. There is poor practice of personal hygiene and unestablished continuous monitoring of personal protective equipment supplies. The preventive measures in the waste collection industry are influenced by several factors. Until the preventive measures are adopted into practice and adapted according to each company's requirements, biological agents continue to be risk factor to the health workers.
    Matched MeSH terms: Hazardous Substances
  18. Ta GC, Jonai H, Mokhtar MB, Peterson PJ
    J Occup Health, 2009;51(6):526-30.
    PMID: 19834280
    Matched MeSH terms: Hazardous Substances/classification*
  19. Karthikeyan V, Gnanamoorthy G, Varun Prasath P, Narayanan V, Sagadevan S, Umar A, et al.
    J Nanosci Nanotechnol, 2020 Sep 01;20(9):5759-5764.
    PMID: 32331175 DOI: 10.1166/jnn.2020.17898
    Herein, we report the facile synthesis, characterization and visible-light-driven photocatalytic degradation of perforated curly Zn0.1Ni0.9O nanosheets synthesized by hydrothermal process. The X-ray diffraction (XRD) and scanning electron microscopy (SEM) studies confirmed the cubic phase crystalline structure and growth of high density perforated curly Zn0.1Ni0.9O nanosheets, respectively. As a photocatalyst, using methylene blue (MB) as model pollutant, the synthesized nanosheets demonstrated a high degradation efficiency of ~76% in 60 min under visible light irradiation. The observed results suggest that the synthesized Zn0.1Ni0.9O nanosheets are attractive photocatalysts for the degradation of toxic organic waste in the water under visible light.
    Matched MeSH terms: Hazardous Substances
  20. Arifin MH, Kayode JS, Ismail MKI, Abdullah AM, Embrandiri A, Nazer NSM, et al.
    J Hazard Mater, 2021 03 15;406:124282.
    PMID: 33199149 DOI: 10.1016/j.jhazmat.2020.124282
    Environmental hazards, industrial, and municipal wastes geochemical and geophysical assessments were carried out at an industrial waste disposal (IWD) site at Bukit Kepong, Kuala Lumpur, Malaysia. RES2-D geophysical method was applied, capable of identification and quantification of the industrial wastes; buried hazardous materials (BHM) and their effects on the subsurface stratum, from the moderately saturated zones, to fully saturated zones housing the aquifer units underneath the water table. Six RES2-D survey profiles were respectively acquired along E-W, and N-S directions. The perpendicular arrangement of the RES2-D survey lines, was tenaciously designed to make possible, the industrial waste materials (IWM)and municipal solid waste (MSW) quantification, with sufficient length of survey lines set at 200 m, and electrode spacing of 5 m, to cover as much details segments of the IWM and MSW as possible. The six RES2-D inversion results, helped in the subsurface stratum classification into three layers, namely; soft layers, which encompasses the waste materials, with varied resistivity values i.e., 0-100 Ω-m, at 10-15 m depths. The consolidated layers produced varied resistivity values i.e., 101-400 Ω-m, at 15-20 m depths. The bedrock has the highest resistivity values i.e., 401-2000 Ω-m, at depths > 20 m. The estimated volume of the waste materials was 312,000 m 3, using 3-D Oasis Montaj modeling via rectangular prism model generated from the inverted RES2-D. Results from the geochemical analysis helped in the validation of the site as a potential contaminated zone with severe health effects.
    Matched MeSH terms: Hazardous Substances
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