Displaying publications 1 - 20 of 31 in total

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  1. Khoo, Kong Soo, Ong, Michael Ah Hup
    Ann Dent, 1998;5(1):-.
    MyJurnal
    The existence of numerous World Wide Web (WWW) sites devoted to dental education is proof that dental educators have been utilizing the pedagogical potential of information technology. Despite the availability of an immense quantity of information on the Internet, performing a search is often a complex, uncoordinated and time-consuming procedure, thus the usefulness of a guide on a topic of interest. Forty WWW sites devoted to dental education have been located using search engines. They were evaluated and classified as follows: guides, electronic publications, databases, patient education and undergraduate education; and according to subjects such as oral biology, morphology, histology, microbiology oral pathology, oral and maxillofacial surgery, radiology, periodontology, dental materials, orthodontics and neuroscience. The extensiveness and quality of some of these sites make them useful resources and knowledge banks for the teacher and the student.
    Matched MeSH terms: Neurosciences
  2. Cyranoski D
    Nature, 2005 Aug 11;436(7052):884-5.
    PMID: 16136648
    Matched MeSH terms: Neurosciences/trends
  3. Idris B, Sayuti S, Abdullah JM
    J Clin Neurosci, 2007 Feb;14(2):148-52.
    PMID: 17161289
    Universiti Sains Malaysia is the only institution in Malaysia which incorporates all fields of the neurosciences under one roof. The integration of basic and clinical neurosciences has made it possible for this institution to become an excellent academic and research centre. This article describes the history, academic contributions and scientific progress of neurosciences at Universiti Sains Malaysia.
    Matched MeSH terms: Neurosciences/history*
  4. Kumar RS, Narayanan SN
    Adv Physiol Educ, 2008 Dec;32(4):329-31.
    PMID: 19047513 DOI: 10.1152/advan.90105.2008
    Matched MeSH terms: Neurosciences/education*
  5. Manveen, K.
    MyJurnal
    Depression is usually discussed as an adult problem; however there is a need to recognize it being a significant problem for children. Rarely is depression focused on how it affects parenting and child outcomes, particularly for young children.Often women are victims of violence, and the devastating effects of depression are significant in such households. However one must not ignore, the effect depression has on parenting, where in these contexts, women themselves, become the perpetrators of violence. When mothers are not well-2 central parental functions are threatened: the ability to foster healthy relationships and to carry out the practical functions of parenting2.When this is not carried out, one sees obvious reductions in young children’s behavioral, cognitive, and social and emotional functioning. Neuroscience is clearly evident that the primary ingredient for healthy early brain development is the quality of the earliest relationships from a baby’s primary caregiver.
    Matched MeSH terms: Neurosciences
  6. Abdullah JM
    Malays J Med Sci, 2013 May;20(3):1-5.
    PMID: 23966818
    President Obama of the United States of America announced this April the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN for short) investment, while Professor Henry Markram's team based in the European Union will spend over a billion euros on the Human Brain Project, breaking through the unknowns in the fifth science of the decade: Neuroscience. Malaysia's growth in the same field needs to be augmented, and thus the Universiti Sains Malaysia's vision is to excel in the field of clinical brain sciences, mind sciences and neurosciences. This will naturally bring up the level of research in the country simultaneously. Thus, a center was recently established to coordinate this venture. The four-year Integrated Neuroscience Program established recently will be a sustainable source of neuroscientists for the country. We hope to establish ourselves by 2020 as a global university with neurosciences research as an important flagship.
    Matched MeSH terms: Neurosciences
  7. Bonn GB
    Front Psychol, 2013;4:920.
    PMID: 24367349 DOI: 10.3389/fpsyg.2013.00920
    This paper examines the concept of free will, or independent action, in light of recent research in psychology and neuroscience. Reviewing findings in memory, prospection, and mental simulation, as well as the neurological mechanisms underlying behavioral control, planning, and integration, it is suggested in accord with previous arguments (e.g., Wegner, 2003; Harris, 2012) that a folk conception of free will as entirely conscious control over behavior should be rejected. However, it is argued that, when taken together, these findings can also support an alternative conception of free will. The constructive nature of memory and an integrative "default network" provide the means for novel and creative combinations of information, such as the imagining of counterfactual scenarios and alternative courses of action. Considering recent findings of extensive functional connections between these systems and those that subsume motor control and goal maintenance, it is argued that individuals have the capability of producing novel ideas and translating them into actionable goals. Although most of these processes take place beneath conscious awareness, it is argued that they are unique to the individual and thus, can be considered a form of independent control over behavior, or free will.
    Matched MeSH terms: Neurosciences
  8. Abdullah JM
    Malays J Med Sci, 2014 Dec;21(Spec Issue):1-5.
    PMID: 25941457
    The Malaysian Journal of Medical Sciences and the Orient Neuron Nexus have amalgated to publish a yearly special issue based on neuro- and brain sciences. This will hopefully improve the quality of peer-reviewed manuscripts in the field of fundamental, applied, and clinical neuroscience and brain science from Asian countries. One focus of the Universiti Sains Malaysia is to strengthen neuroscience and brain science, especially in the field of neuroinformatics.
    Matched MeSH terms: Neurosciences
  9. Idris Z, Kandasamy R, Reza F, Abdullah JM
    Asian J Neurosurg, 2014 Jul-Sep;9(3):144-52.
    PMID: 25685205 DOI: 10.4103/1793-5482.142734
    BACKGROUND: Magnetoencephalography (MEG) is a method of functional neuroimaging. The concomitant use of MEG and electrocorticography has been found to be useful in elucidating neural oscillation and network, and to localize epileptogenic zone and functional cortex. We describe our early experience using MEG in neurosurgical patients, emphasizing on its impact on patient management as well as the enrichment of our knowledge in neurosciences.
    MATERIALS AND METHODS: A total of 10 subjects were included; five patients had intraaxial tumors, one with an extraaxial tumor and brain compression, two with arteriovenous malformations, one with cerebral peduncle hemorrhage and one with sensorimotor cortical dysplasia. All patients underwent evoked and spontaneous MEG recordings. MEG data was processed at band-pass filtering frequency of between 0.1 and 300 Hz with a sampling rate of 1 kHz. MEG source localization was performed using either overdetermined equivalent current dipoles or underdetermined inversed solution. Neuromag collection of events software was used to study brain network and epileptogenic zone. The studied data were analyzed for neural oscillation in three patients; brain network and clinical manifestation in five patients; and for the location of epileptogenic zone and eloquent cortex in two patients.
    RESULTS: We elucidated neural oscillation in three patients. One demonstrated oscillatory phenomenon on stimulation of the motor-cortex during awake surgery, and two had improvement in neural oscillatory parameters after surgery. Brain networks corresponding to clinico-anatomical relationships were depicted in five patients, and two networks were illustrated here. Finally, we demonstrated epilepsy cases in which MEG data was found to be useful in localizing the epileptogenic zones and functional cortices.
    CONCLUSION: The application of MEG while enhancing our knowledge in neurosciences also has a useful role in epilepsy and awake surgery.
    KEYWORDS: Awake craniotomy; brain network; epilepsy; magnetoencephalography; neural oscillation
    Matched MeSH terms: Neurosciences
  10. Sethi S, Chourasia D, Parhar IS
    J Biosci, 2015 Sep;40(3):607-27.
    PMID: 26333406
    An extensive guide on practicable and significant quantitative proteomic approaches in neuroscience research is important not only because of the existing overwhelming limitations but also for gaining valuable understanding into brain function and deciphering proteomics from the workbench to the bedside. Early methodologies to understand the functioning of biological systems are now improving with high-throughput technologies, which allow analysis of various samples concurrently, or of thousand of analytes in a particular sample. Quantitative proteomic approaches include both gel-based and non-gel-based methods that can be further divided into different labelling approaches. This review will emphasize the role of existing technologies, their advantages and disadvantages, as well as their applications in neuroscience. This review will also discuss advanced approaches for targeted proteomics using isotope-coded affinity tag (ICAT) coupled with laser capture microdissection (LCM) followed by liquid chromatography tandem mass spectrometric (LC-MS/MS) analysis. This technology can further be extended to single cell proteomics in other areas of biological sciences and can be combined with other 'omics' approaches to reveal the mechanism of a cellular alterations. This approach may lead to further investigation in basic biology, disease analysis and surveillance, as well as drug discovery. Although numerous challenges still exist, we are confident that this approach will increase the understanding of pathological mechanisms involved in neuroendocrinology, neuropsychiatric and neurodegenerative disorders by delivering protein biomarker signatures for brain dysfunction.
    Matched MeSH terms: Neurosciences/methods*
  11. Raffiq A, Abdullah JM, Haspani S, Adnan JS
    Malays J Med Sci, 2015 Dec;22(Spec Issue):5-8.
    PMID: 27006632 MyJurnal
    The development of neurosurgical services and training in Malaysia began in 1963, with the first centre established in its capital city at Hospital Kuala Lumpur, aimed to provide much needed neurosurgical services and training in the field of neurology and neurosurgery. This center subsequently expanded in 1975 with the establishment of the Tunku Abdul Rahman Neuroscience Institute (IKTAR); which integrated the three allied interdependent disciplines of neurosurgery, neurology and psychiatry. The establishment of this institute catalysed the rapid expansion of neurosurgical services in Malaysia and paved the way for development of comprehensive training for doctors, nurses, and paramedics. This culminated in the establishments of a local comprehensive neurosurgery training program for doctors in 2001; followed by a training program for nurses and paramedics in 2006. To date, there are more than 60 neurosurgeons providing expert care in 11 centers across Malaysia, along with trained personnel in the field of neurosciences.
    Matched MeSH terms: Neurosciences
  12. Abdullah JM
    Malays J Med Sci, 2015 Dec;22(Spec Issue):1-4.
    PMID: 27006631
    12 months ago the first Neuroscience special issue of the Malaysia Journal of Medical Sciences was born with the intention to increase the number of local publication dedicated to neurosciences. Since then many events happened in the neuroscience world of Malaysia, those considered major were the establishment of a Neurotechnology Foresight 2050 task force by the Academy of Medicine Malaysia as well as the launching of Malaysia as the 18th member to join the International Neuroinformatics Coordinating Facility on the 9th October 2015 which was officiated by the Deputy Ministers of Higher Education, Datuk Mary Yap.
    Matched MeSH terms: Neurosciences
  13. Mohd Ibrahim SD, Muda M
    Malays J Med Sci, 2015 Jul-Aug;22(4):64-8.
    PMID: 26715909 MyJurnal
    Sekolah Menengah Sains Tengku Muhammad Faris Petra (SMSTMFP) and Sekolah Kebangsaan Kubang Kerian (3) (SKKK3) were selected by the Department of Neurosciences, Universiti Sains Malaysia (USM), in 2011 to be a 'school-based Neuroscience Club' via the 'Knowledge Transfer Programme (KTP) - Community' project. This community project was known as "The Brain Apprentice Project". The objectives of this project were to promote science and the neurosciences beyond conventional classroom teachings whilst guiding creativity and innovation as well as to assist in the delivery of neuroscience knowledge through graduate interns as part of the cultivation of neuroscience as a fruitful future career option. All of the planned club activities moulded the students to be knowledgeable individuals with admirable leadership skills, which will help the schools produce more scientists, technocrats and professionals who can fulfil the requirements of our religion, race and nation in the future. Some of the activities carried out over the years include the "My Brain Invention Competition", "Mini Brain Bee Contest", "Recycled Melody" and "Brain Dissection". These activities educated the students well and improved their confidence levels in their communication and soft skills. The participation of the students in international-level competition, such as the "International Brain Bee", was one of the ways future professionals were created for the nation. The implementation of Neuroscience Club as one of the organisations in the school's cocurriculum was an appropriate step in transferring science and neuroscience knowledge and skills from a higher education institution, namely USM, to both of the schools, SMSTMFP and SKKK3. The club members showed great interest in all of the club's activities and their performance on the Ujian Pencapaian Sekolah Rendah (UPSR) or Primary School Achievement Test and Sijil Pelajaran Malaysia (SPM) or Malaysian Certificate of Education examinations improved tremendously.
    Matched MeSH terms: Neurosciences
  14. Baharuddin A, Musa MN, Salleh SS
    Malays J Med Sci, 2016 Jan;23(1):1-3.
    PMID: 27540319 MyJurnal
    Muslim relies on the structure or guideline of shari'ah or the maqasid al-shariah, which consist of five essential values, namely preservation/protection of faith, life, intellect, property, and dignity/lineage - to guide them in discovering guiding principles for new concerns such as posed by neuroscience. Like in the case of brain imaging technology, there is in need for proper explanation within Islamic and among the Muslim scientists/scholars on how Islamic beliefs, values, and practices might cumulatively provide 'different' meanings to the practice and application of this technology, or whether it is in line with the shari'ah - in the context of preservation of health and protection of disease. This paper highlights the Islamic mechanism for neuroethics as basis for a holistic ethical framework of neuroscience to cope with its new, modern, and emerging technologies in the globalised world, and how Muslim should response to such changes.
    Matched MeSH terms: Neurosciences
  15. Kasabov N, Scott NM, Tu E, Marks S, Sengupta N, Capecci E, et al.
    Neural Netw, 2016 Jun;78:1-14.
    PMID: 26576468 DOI: 10.1016/j.neunet.2015.09.011
    The paper describes a new type of evolving connectionist systems (ECOS) called evolving spatio-temporal data machines based on neuromorphic, brain-like information processing principles (eSTDM). These are multi-modular computer systems designed to deal with large and fast spatio/spectro temporal data using spiking neural networks (SNN) as major processing modules. ECOS and eSTDM in particular can learn incrementally from data streams, can include 'on the fly' new input variables, new output class labels or regression outputs, can continuously adapt their structure and functionality, can be visualised and interpreted for new knowledge discovery and for a better understanding of the data and the processes that generated it. eSTDM can be used for early event prediction due to the ability of the SNN to spike early, before whole input vectors (they were trained on) are presented. A framework for building eSTDM called NeuCube along with a design methodology for building eSTDM using this is presented. The implementation of this framework in MATLAB, Java, and PyNN (Python) is presented. The latter facilitates the use of neuromorphic hardware platforms to run the eSTDM. Selected examples are given of eSTDM for pattern recognition and early event prediction on EEG data, fMRI data, multisensory seismic data, ecological data, climate data, audio-visual data. Future directions are discussed, including extension of the NeuCube framework for building neurogenetic eSTDM and also new applications of eSTDM.
    Matched MeSH terms: Neurosciences
  16. Stahnisch FW, Hor JY
    J Hist Neurosci, 2016 Oct-Dec;25(4):423-36.
    PMID: 27379572 DOI: 10.1080/0964704X.2016.1175188
    Matched MeSH terms: Neurosciences/history*
  17. Tumiran MA, Abdul Rahman NN, Mohd Saat R, Ismail AZ, Ruzali WAW, Bashar NKN, et al.
    J Relig Health, 2018 Feb;57(1):1-11.
    PMID: 26160145 DOI: 10.1007/s10943-015-0079-5
    Diseases involving the nervous system drastically change lives of victims and commonly increase dependency on others. This paper focuses on senile dementia from both the neuroscientific and Islamic perspectives, with special emphasis on the integration of ideas between the two different disciplines. This would enable effective implementation of strategies to address issues involving this disease across different cultures, especially among the world-wide Muslim communities. In addition, certain incongruence ideas on similar issues can be understood better. The former perspective is molded according to conventional modern science, while the latter on the analysis of various texts including the holy Qur'an, sunnah [sayings and actions of the Islamic prophet, Muhammad (pbuh)] and writings of Islamic scholars. Emphasis is particularly given on causes, symptoms, treatments and prevention of dementia.
    Matched MeSH terms: Neurosciences
  18. Abdullah JM
    Malays J Med Sci, 2018 Mar;25(2):1-14.
    PMID: 30918450 DOI: 10.21315/mjms2018.25.2.1
    People can work wonders without a room. Rooms make people think within a box, and people who are not confined within a room can wonder while thinking and solve problems as they see them in the environment. The dearth in the growth of professionals trained in the neurosciences who will use neurotechnology in the future is a dire situation facing Malaysia, according to the Academy of Sciences Malaysia's 2017 Emerging Science, Engineering and Technology (ESET) study. Further, this human resource needs to be fundamentally cultivated at schools from a very young age. The author describes the activities that have taken place in the country via a bottom-up approach over the last two years and hopes that eventually these endeavours will end with the creation of an ASEAN Brain, Mind, Behaviour and Neuroscience Institute for Creativity and Innovation being established with the full support of the Government of Malaysia or other local and international financial donors.
    Matched MeSH terms: Neurosciences
  19. Balogun WG, Cobham AE, Amin A, Seeni A
    Neuroscience, 2018 03 15;374:323-325.
    PMID: 29427653 DOI: 10.1016/j.neuroscience.2018.01.062
    Neuroscience research and training in many African countries are difficult due to funding and infrastructure deficit. This has resulted in few neuroscientists within Africa. However, invertebrates such as Drosophila and Caenorhabditis elegans could provide the perfect answer to these difficulties. These organisms are cheap, easy to handle and offer a comparable advantage over vertebrates in neuroscience research modeling because they have a simple nervous system and exhibit well-defined behaviors. Studies using invertebrates have helped to understand neurosciences and the complexes associated with it. If Africa wants to catch up with the rest of the world in neuroscience research, it needs to employ this innovative cost-effective approach in its research. To improve invertebrate neuroscience within the Africa continent, the authors advocated the establishment of invertebrate research centers either at regional or national level across Africa. Finally, there is also a need to provide public funding to consolidate the gains that have been made by not-for-profit international organizations over the years.
    Matched MeSH terms: Neurosciences/economics; Neurosciences/methods*
  20. Balogun WG, Cobham AE, Amin A
    Metab Brain Dis, 2018 04;33(2):359-368.
    PMID: 28993966 DOI: 10.1007/s11011-017-0119-9
    The science of the brain and nervous system cuts across almost all aspects of human life and is one of the fastest growing scientific fields worldwide. This necessitates the demand for pragmatic investment by all nations to ensure improved education and quality of research in Neurosciences. Although obvious efforts are being made in advancing the field in developed societies, there is limited data addressing the state of neuroscience in sub-Saharan Africa. Here, we review the state of neuroscience development in Nigeria, Africa's most populous country and its largest economy, critically evaluating the history, the current situation and future projections. This review specifically addresses trends in clinical and basic neuroscience research and education. We conclude by highlighting potentially helpful strategies that will catalyse development in neuroscience education and research in Nigeria, among which are an increase in research funding, provision of tools and equipment for training and research, and upgrading of the infrastructure at hand.
    Matched MeSH terms: Neurosciences/trends*
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