Kajian berbentuk hirisan lintang ini dijalankan untuk mengkaji hubungan antara keterlibatan aktiviti di kolej kediaman dengan status pemakanan pelajar Universiti Kebangsaan Malaysia (UKM) Kuala Lumpur dan menentukan tabiat makan pelajar serta kebolehdapatan makanan sihat di sekitar mereka. Seramai 106 pelajar tahun dua hingga empat UKM Kuala Lumpur terlibat dalam kajian ini (20.8% lelaki dan 79.2% perempuan). Data pengambilan makanan subjek direkod dengan menggunakan diari makanan tiga hari. Keterlibatan subjek dalam aktiviti kolej dan juga kebolehdapatan makanan sihat ditentukan dengan menggunakan borang soal selidik yang dibentuk khas untuk kajian ini. Berat badan, ketinggian, ukurlilit pinggang, peratus lemak tubuh dan Indeks Jisim Tubuh (IJT) juga diukur. Hasil kajian menunjukkan majoriti daripada subjek (62.3%) terlibat secara aktif dengan aktiviti yang diadakan di kolej kediaman. Daripada peratusan ini, 5.3% daripada subjek lelaki dan 31.9% perempuan adalah kurang berat badan. 68.4% subjek lelaki dan 55.3% perempuan mempunyai berat badan normal. 21% subjek lelaki dan 8.5% perempuan adalah pra obes. Tambahan pula, 5.3% (n = 1) subjek lelaki dan 4.3% (n = 2) daripada subjek perempuan tergolong dalam klasifi kasi IJT obes. Kajian ini mendapati majoriti subjek bersetuju bahawa mudah untuk memperolehi makanan sihat di kampus. Terdapat korelasi positif yang signifi kan di antara pengambilan tenaga (r = 0.352, p < 0.05) dan lemak (r = 0.391, p < 0.05) dengan Indeks Jisim Tubuh (IJT) bagi penglibatan terhadap aktiviti kolej yang kurang daripada tiga jam. Bagi penglibatan terhadap aktiviti kolej yang lebih daripada tiga jam pula, terdapat korelasi positif yang signifi kan di antara pengambilan tenaga (r = 0.678, p < 0.01), lemak (r = 0.550, p < 0.05), karbohidrat (r = 0.685, p < 0.01), protein (r = 0.465, p < 0.05), kalsium (r = 0.357, p < 0.05), ferum (r = 0.500, p < 0.05), vitamin A (r = 0.733, p < 0.01) dan vitamin E (r = 0.582, p < 0.05) dengan IJT. Pencapaian ‘Recommended Nutrient Intake’ (RNI) bagi pengambilan tenaga, kalsium, ribofl avin, vitamin C dan vitamin E adalah lebih tinggi bagi subjek yang terlibat dengan aktiviti kolej kurang daripada tiga jam berbanding dengan subjek yang terlibat dengan aktiviti kolej lebih daripada tiga jam. Kesimpulannya, walaupun ramai subjek yang aktif, masih terdapat dalam kalangan mereka yang mengalami masalah kurang berat badan, lebih berat badan dan obes. Oleh yang demikian, penglibatan dalam aktiviti di kolej kediaman memberi kesan kepada status pemakanan pelajar Universiti Kebangsaan Malaysia.
Penentuan kumpulan bangsa dalam analisis rambut pada kepala adalah satu cabaran yang dihadapi dalam analisis forensik untuk mengenal pasti mangsa, suspek dan tempat kejadian jenayah. Kajian ini bertujuan untuk mengenal pasti perbezaan antara dua kaum terbesar di Malaysia iaitu Melayu dan Cina melalui penelitian ciri-ciri rambut. Ini termasuklah ciri umum rambut, corak kutikel, warna, taburan pigmen kortek dan ciri medula – jenis, ketebalan dan indeks medula. Kajian ini telah dijalankan dengan menggunakan mikroskop cahaya dan terdiri daripada lima langkah iaitu penyediaan sampel, penelitian ciri umum rambut, penyediaan dan penelitian slaid acuan corak sisik kutikel, slaid kortek serta medula. Hasil daripada kajian in mendapati bahawa kebanyakan Melayu mempunyai warna pigmen yang bercoklat gelap manakala Cina mempunyai pigmen coklat cerah. Kami juga mendapati bahawa ketebalan medula boleh juga digunakan untuk membezakan antara Melayu dan Cina di mana nilai purata bagi Melayu dan Cina masing-masing adalah 7.59 ± 1.45 μm dan 9.12 ± 1.85 μm. Nilai purata indeks medula bagi Melayu dan Cina pula adalah 0.17 ± 0.02 μm dan 0.18 ± 0.02 μm masing-masing. Walaupun begitu, ciri-ciri seperti tekstur, ketebalan rambut, corak sisik kutikel, taburan pigmen dan jenis medula pula menunjukkan perbezaan yang tidak ketara antara Melayu dan Cina. Kesimpulannya, kajian ini telah menunjukkan bahawa warna pigmen, ketebalan medula dan indeks medula adalah ciri-ciri penting yang boleh digunakan untuk menentukan bangsa.
Ficus deltoidea leaves were widely used as a tea beverages in Malaysia with no information of its mineral content. Hence the mineral content of two species of Ficus deltoidea leaves were investigated. The dried leaves of F. deltoidea var. angustifolia and F. deltoidea var. deltoidea were acid digested and mineral elements of Na, Mg, K, Ca, Mn, Cr, Fe and Zn were determined using ICP–MS. Magnesium, potassium, sodium, manganese, iron and zinc were found to be present in the leaves of F. deltoidea var. angustifolia and F. deltoidea var. deltoidea. Concentration of magnesium (1934 mg/L), manganese (58.37 mg/L), iron (6.89 mg/L) and zinc (1.77 mg/L) in F. deltoidea var. deltoidea species were significantly (P < 0.05) higher than in F. deltoidea var. angustifolia species with concentration of 317 mg/L, 29.62 mg/L, 4.55 mg/L and 1.26 mg/L for magnesium, manganese, iron and zinc respectively. Meanwhile, concentration of sodium in F. deltoidea var. deltoidea species (3.13 mg/L) was found to be significantly (P < 0.05) lower than the concentration in F. deltoidea var. angustifolia species (9.11 mg/L). The finding showed that the leaves of F. deltoidea var. deltoidea has higher nutritional value than the leaves of F. deltoidea var. angustifolia. Leaves of Ficus deltoidea especially the F. deltoidea var. deltoidea species contain high amount of magnesium, manganese and potassium. Therefore, tea made of this leaves can be served as a good source of minerals for human consumption.
Obesity prevalence and body image consciousness are on the rise, and women often try to lose weight using a variety of methods. This paper reports the knowledge on body weight management amongst working women aged 30 – 45 years in Kuala Lumpur. Respondents comprised 131 school teachers and 122 civil servants. Anthropometric measurements included body weight and height; while knowledge on weight management was assessed using a questionnaire. The respondents were Malay (64%), Chinese (26%) and Indian women (10%) with mean age of 38.3 ± 4.6 years old. The respondents were grouped into two weight categories based on body mass index (BMI): normal weight (BMI 18.5 to 24.9 kg/m2) and overweight (BMI ≥ 25.0 kg/m2). Mean body weight and BMI were significantly different (p < 0.001) between the two weight categories. Overweight and normal weight groups had mean body weight of 69.0 ± 9.5 kg and 53.5 ± 5.3 kg; while mean BMI were 29.2 ± 3.6 kg/ m2 dan 21.9 ± 1.7 kg/m2; respectively. Mean scores for knowledge on weight management were similar for both weight categories, 62.4 ± 13.7 and 61.8 ± 13.4 for overweight and normal weight, respectively. A majority of overweight (71%) and normal weight (73%) women had moderate level (scores 50–74%) of weight management knowledge. However, it was interesting to note that there were more overweight women (20%) who had high knowledge level (scores ≥ 75%) as compared to normal weight women (15%). Only 9% of overweight and 12% of normal weight women demonstrated low knowledge level (scores <50%). School teachers were significantly (p < 0.001) more knowledgeable than civil servants in weight management matters with mean knowledge scores of 65.5 ± 12.3 and 58.4 ± 13.9, respectively. On the whole, the results indicated that women were fairly knowledgeable in healthy body weight management. Knowledge on body weight management is essential for preventing comorbidity risks related to overweight problem. The study also revealed that there was a need for nutrition education related to body image and effective weight management. Key words: Body weight management, working women, overweight, obesity
The purpose of this study was to identify the most common forms of age-related cataracts and to estimate possible risk factors for age-related cataracts in a sample of cataract patients at the National University of Malaysia Hospital. Thirty five patients (17 males and 18 female) with cataracts were recruited from the ophthalmology ward and clinic at the hospital. The age range of the patients was between 39 to 93 years (mean 64.9 11.5 years). The Lens Opacities Classification System (Locs) III was used to grade nuclear, cortical and posterior subcapsular lens opacities. Grading of the cataract was carried out and the following information was collected: initial visual acuity and best-corrected visual acuity, demographic details, health history, dietary intake of antioxidants and lifetime ocular ultraviolet B exposure. Analyses were conducted using a standard case-control design. T-tests were used to assess the significance of continuous variables and chi-squared tests were used for categorical variables. The overall prevalence of cortical cataract was 34.4% (12 patients), nuclear cataract was 60.0% (21 patients), and posterior subcapsular cataract was 57.1% (20 patients). No significant potential risk factor was found for nuclear cataracts. In the case of posterior subcapsular cataract, hypertension was the only potential significant risk factor (x2 = 4.38, p = 0.036), and in the case of cortical cataract, cigarette smoking was the only significant risk factor. Although lifetime effective ocular UV-B exposure was found to be not a significant potential risk factor, but it was seen that for cortical cataracts, the mean difference of lifetime effective ocular UV-B exposure between those with cortical and those without cortical cataracts was larger compared to others with nuclear and posterior subcapsular cataracts. Hypertension was found to be a potential significant risk factor for posterior subcapsular cataract whereas cigarette smoking was a potentially significant risk factor for cortical cataract. Although not statistically significant, lifetime effective ocular UV-B exposure maybe a potential risk factor for cortical cataract.
The study examined the use of linguistic contextual cues among native, Malay-speaking normal hearing young adults. Ten undergraduate students of Universiti Kebangsaan Malaysia participated in the study. All subjects had normal hearing with the average hearing threshold levels for the overall left and the right ears of 7.8 dB (SD 4.1). The Malay Hearing in Noise Test (MyHINT) materials were employed and presented to the subjects at an approximately 65 dBA presentation level. Testing was conducted in a sound field in three different listening conditions: in quiet, in noise with +5 dB signal-to-noise ratio (SNR) and 0 dB SNR. In every test condition, three lists of MyHINT were administered to each subject. The magnitude of context effects was measured using the j factor, which was derived from measurements of recognition probabilities for whole sentences (13,) and the constituent words in the sentences (PP) in which j = log P./ log P P. Results showed that all subjects scored 100% identification of words in sentences and whole sentences in quiet listening condition, while subjects' performances in 0 dB SNR were significantly poorer than that in quiet and in +5 dB SNR (p < 0.001). The j-values were significantly correlated with the probability of recognizing words in the sentences (r = 0.515, p = 0.029) in which lower j values were associated with lower P ps. Subjects were not significantly different from each other in their use of contextual cues in adverse listening conditions [F(9, 7) = 1.34, p = 0.359]. Using the linear regression function for j on word recognition probabilities, the predicted P. were calculated. It was found that the predicted and measured probabilities of recognizing whole sentences were highly correlated: r = 0.973, p < 0.001. The results suggested that linguistic contextual information become increasingly important for recognition of sentences by normal hearing young adult listeners as SNR deteriorates.
This paper attempts to examine the real values of Malaysian herbal products in the aspects of quality, safety and efficacy as curing agents. In so doing it will also determine the driving force behind the intense public interest for herbal medicine as alternative or complementary to conventional medicine. Most herbal products in the Malaysian market are not sufficiently provided with information on their ingredients, indications, dosage, pharmacology, contraindications and possible side-effects. Most published information on the products on evidence of safety and efficacy is not supported with scientific evidence. The present practice of traditional medicine still depend heavily on information obtained through ethnopharmacological experiences. However, the herbal product market is experiencing a tremendous growth and there is an increased trend of incorporating herbal therapy into modern medical practice by many mainstream health professionals. Unfortunately, the popularity of herbal products is more associated with consumer attitudes and the ability of the herbalists to influence rather than their true quality as medicinal agents. Many people are exploited due to ignorance on the real value of herbals as therapeutic agents. It is especially disappointing when popular media, promotional literature and talk shows by individuals promoting quackery are given much publicity. Even worse, many individuals trained in the health sciences are promoting quackery. This has often left the consumers with the perception that the authority condones the improper use of herbal products. Thus, it is important for pharmacists and physicians to be trained in traditional herbal medicine so that they can educate the public on the benefits, quality, safety and proper use of herbal products.
The water decoction of Labisia pumila var. alata is used traditionally in childbirth, as well as for the treatment of flatulence, dysentery, dysmenorrhoea and join pains. This study was carried out to determine the best method and optimum parameters of aqueous axtraction of the leaves and roots of this species. The laboratory methos esed were maceration, ddecoction, reflux and Saxhlet, whereas the parameters studied were temperature, duration and pH of axtraction. The yields and thin layer chromatographic profiles of the freeze-dried extracts were analysed. The study showed that in general the percentage yields of the water soluble extracts were higher for the roots than the leaves, as well as the extracts obtained from heating than those obtained at room temperature. The most effective extraction parameters for L. pumila var. alata were as follows:maceration (25 C, at least 6 hr), decoction (60 C, not exceeding 10 min) and reflux (100 C, not exceeding 4 hr). Saxhlet method was found to be the least effective. The pH analysis had shown the possibility of degradation of some of the phytochemicals at extreme pH values of 1,2 and 14.
Tujuan kajian ini adalah untuk menilai sifat-sifat fizikokimia Radix Glycyrrhizae sebagai bahan eksipien untuk pembuatan tablet dengan kaedah pemampatan terus dan membandingkannya dengan eksipien komersil iaitu laktosa, selulosa mikrohablur (MCC) dan kalsium laktat pentahidrat (Puracal). Saiz partikel untuk semua sampel yang digunakan dalam kajian ini dihadkan pada 200-250µm. Hasil imbasan elektron mikroskop menunjukkan partikel Radix Glycyrrhizae mempunyai kepelbagaian saiz dan bentuk yang tidak seragam seperti laktosa berbanding MCC yang lebih bersifat jejarum dan Puracal yang bersifat sfera dan poros. Keupayaan sampel untuk dimampatkan, ketumpatan partikel sampel, kesan kelembapan ke atas tegasan pengenduran dan keliangan tablet diuji serta dibandingkan dengan eksipien komersil yang lain. Sifat ikatan dari sampel Radix Glycyrrhizae ini pula dikaji dengan menghitung kekuatan tegangan melalui kaedah pemampatan diametral dan turut dilakukan perbandingan. Radix Rlycyrrhizae memiliki ketumpatan sebenar serbuk iaitu 1.5746 g/cc manakala laktosa, selulosa mikrohablur dan kalsium laktat pentahidrat masing-masing 1.5476, 1.6654 dan 1.3506 g/cc. Radix Rlycyrrhizae juga di dapati mempunyai daya ketermampatan yang sederhana sebagaimana laktosa berbanding Puracal dan MCC yang jauh lebih baik sifatnya. Kajian kesan kelembapan menunjukkan kekuatan tablet Radix Glycyrrhizae, Puracal, laktosa dan MCC dipengaruhi perubahan suhu. Hasil kajian analisis Heckel pula menunjukkan bahawa Radix Glycyrrhizae bersifat aliran plastik sebagaimana MCC manakala laktosa dan Puracal lebih bersifat rapuh. Keputusan ujian ke atas sifat pemampatan dan pemadatan mendapati bahawa Radix Kesimpulannya, Radix Glycyrrhizae boleh digunakan sebagai eksipien dalam pembuatan tablet melalui kaedah pemampatan terus dan ciriciri fisikokimianya sebagai eksipien adalah setanding dengan eksipien komersial.
Tujuan kajian ini adalah untuk mengenal pasti punca insidens tinggi infeksi Acanthamoeba di kalangan pemakai kanta sentuh di Kuala Lumpur. Satu ratus tujuh puluh empat sampel diambil dari 66 subjek pemakai kanta sentuh lembut jenis pakaibuang dan mereka juga disoal dengan menggunakan borang kaji selidik. Kesemua pemakai kanta sentuh menggunakan pelbagai jenis larutan disinfeksi atau larutan pelbagai guna untuk membersih dan mendisinfeksi kanta sentuh. Swab diambil dari kanta sentuh yang masih dipakai, bekas kanta sentuh dan juga larutan disinfeksi yang sedang digunakan. Daripada swab ini proses pengkulturan yang lengkap dilakukan untuk pemencilan Acanthamoeba spp. Pemencilan Acanthamoeba spp. daripada 14 sampel daripada 7 subjek telah berjaya dilakukan. Hasil pemencilan yang tinggi adalah daripada bekas kanta sentuh (13.5%) dan kanta sentuh subjek (10.6%). Walau bagaimanapun tiada sebarang pemencilan didapati daripada larutan disinfeksi. Punca infeksi Acanthamoeba adalah dari bekas simpanan kanta sentuh dan kanta sentuh yang dipakai. Kaji selidik menunjukkan peratusan tidak komplain yang tinggi di kalangan pemakai kanta sentuh kerana ramai menggunakan air paip untuk mencuci kanta sentuh dan bekasnya.
Kajian garis pangkal pengimejan resonans magnet kefungsian (fMRI) telah dijalankan di Jabatan Radiologi, Hospital Universiti Kebangsaan Malaysia ke atas seorang subjek lelaki sihat berumur 25 tahun menggunakan sistem pengimejan resonans magnet (MRI) 1.5 T. Kajian ini menggunakan gerakan jari tangan kanan dan kiri untuk merangsang aktiviti neuron di dalam korteks serebrum. Subjek diarahkan supaya menekan jari-jari pada ibu jari secara bergilir-gilir semasa imbasan kefungsian dilakukan. Paradigma 5 kitar aktifrehat digunakan dengan setiap kitar masing-masing mengandungi 20 siri pengukuran. Keputusan menunjukkan bahawa rantau otak yang aktif akibat gerakan jari adalah girus presentral merangkumi kawasan motor primer. Pengaktifan otak adalah secara kontralateral terhadap gerakan jari tangan kanan dan kiri. Keamatan isyarat keadaan aktif didapati lebih tinggi daripada keamatan isyarat keadaan rehat. Analisis yang dilakukan ke atas beberapa rantau pengaktifan yang diminati (ROI) pada beberapa hirisan menunjukkan perbezaan yang bererti (p < 0.05) antara keamatan keadaan aktif dan rehat untuk nilai ambang statistik (Z) = 1.0 dan 1.5. Perbezaan purata antara kedua-dua purata keamatan isyarat keadaan aktif dan rehat pada manamana hirisan untuk kedua-dua nilai Z menunjukkan magnitud pengaktifan yang lebih tinggi pada hemisfera kanan otak iaitu apabila subjek menggerakkan tangan kirinya. Bilangan voksel yang aktif juga didapati lebih tinggi pada hemisfera kanan berbanding pada hemisfera kiri otak. Keputusan ini menyokong fakta bahawa bagi subjek yang tidak kidal, kawasan pengaktifan motor pada hemisfera kanan otak semasa gerakan jari tangan kiri mengalami rangsangan hemodinamik yang lebih tinggi berbanding dengan hemisfera kiri otak semasa gerakan jari tangan kanan. Fenomena rangsangan hemodinamik yang diperhatikan dalam kajian ini dibincangkan berdasarkan kepada kebergantungan kontras isyarat kepada aras oksigen darah (BOLD).
This study in the management of dysphagia or swallowing disorders involved 72 contactable Speech-Language Pathologists (SLP) in Malaysia. A survey was undertaken to identify the patterns of dysphagia management by SLPs in Malaysia by identifying the percentage of SLPs in Malaysia who have managed swallowing disorders, the approximate number of patients, assessment and therapy techniques used, other professional involvement and the factors that influenced the confidence levels of the SLPs in managing swallowing disorders. Fifty percent (50%) of the forty four SLPs (61.6%) who responded to the survey had previously managed swallowing disorders. It was estimated that 5% (430 of 8268) of patients referred to the SLPs in Malaysia presented with dysphagia and were subsequently managed for their swallowing problems. The oromotor examination was carried out most frequently (100%) for evaluation of dysphagia while the compensatory technique proved to be the most frequently used management technique (77.3%). Most referrals to the SLPs were received from the neurosurgeon (59.1%); the otorhinolaryngologist was most referred to by the SLPs (50%). By using the Chi-squared analysis, it was found that clinical training in dysphagia at the undergraduate or post-graduate levels influenced the confidence levels of the SLPs in managing dysphagia cases (χ2 = 10.063 with p value = 0.007).
Kajian garis pangkal pengimejan resonans magnet kefungsian (fMRI) telah dijalankan ke atas 2 orang subjek lelaki sihat (kidal dan tidak kidal) masing-masing berumur 22 dan 25 tahun. Imbasan fMRI dijalankan menggunakan sistem pengimejan resonans magnet (MRI) 1.5 T di Jabatan Radiologi, Hospital Universiti Kebangsaan Malaysia. Kajian ini menggunakan gerakanjari tangan kanan dan kiri untuk merangsang aktiviti neuron di dalam korteks serebrum. Paradigma 5 kitar aktifIrehat digunakan dengan setiap kitar mengandungi satu blok aktif dan satu blok rehat yang masing-masing mengandungi 10 siri pengukuran. Imej fMRI dianalisis menggunakan pekej perisian MatLab dan pemetaan statistik berparameter 2 (sPM2). Proses pendaftaran jasad tegar menggunakan penjelmaan afin 6 parameter dilakukan ke atas kesemua imej kefungsian berwajaran T2*. Keputusan menunjukkan bahawa pergerakan subjek adalah minimum sama ada dalam arah translasi (< 1 mm) atau putaran (< 1 ). Kesemua imej dinormalkan melalui proses peledingan tak linear menggunakan penjelmaan afin 12 parameter dan didapati sepadan dengan pencontoh yang telahpun mematuhi ruang anatomi piawai. Walau bagaimanapun, bentuk, resolusi dan kontras imej kefungsian telah berubah sedikit berbanding dengan imej asal. Pelicinan imej menggunakan kernel Gaussian isotropik 6 mm menyebabkan data imej lebih bersifat parametrik dengan kehilangan yang ketara dalam resolusi dan kontras. Pengasingan struktur yang dilakukan ke atas imej berwajaran T1 mengklaskan tisu otak kepadajirim kelabu, jirim putih dan bendalir serebrospina. Pasca pemprosesan ruang bagi imej kefungsian dan struktur menjadikan data imej bersifat parametrik dengan taburan jenis Gaussian dan sedia untuk dianalisis menggunakan model linear am dan teori medan rawak Gaussian.
A vision screening study was carried out among Indian schoolchildren around Kuala Lumpur to determine whether the prevalence of myopia was higher in boys or girls. Altogether 749 students (49.7% boys and 50.3% girls) aged 7-18 years were screened and their refractive error examined using retinoscopy without cycloplegia. For the right eye 15.1% of the girls' eyes were found to be myopic as compared to 16.9% of the boys, of which chi-square showed no significant difference (p = 0.44). For the left eye 18.8% of the girls' eyes were myopic as compared to 16.4% of the boys. Chi square also showed no significant difference (p = 0.26). When high myopia (> -6.00D) was considered, there was no difference found between boys and girls. The number of students with high myopia greater than -6.00D was also very small (0.3%-0.5%). In conclusion, it was found that there was no significant difference in myopia between girls and boys among Indian schoolchildren.
This paper reports a clinical case study on the effectiveness of Cognitive-Behavioral Treatment (CBT) in treating panic attack with agoraphobia in a local health psychology clinic. M.N., a 24 year old male, complained of nightmares, heart palpitations, sweating, tremors and fearful feelings for the past one and a half years. He felt anxious about going to crowded places such as bus stations, night markets, supermarkets, and mosques and being left alone in any place which he was not familiar with. This case study adopted an ABC design whereby the subject was assessed at three different phases: pre-treatment, mid-treatment and post-treatment. Four standard assessment measures were administered: Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Anxiety Scale of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and State-Trait Anxiety Inventory (STAI). The subject responded well to 12 sessions of intervention employed in the study based on CBT model and this could be noticed by minimal score on the entire psychological test administered. The application of behavioral and cognitive strategies became more effective due to patient’s ability to understand and also due to his cooperative behavior. He responded well to imagery exposure and in-vivo gradual exposure and successfully went to shopping malls, used lifts at Kuala Lumpur Tower, went to night markets and used public transport.
Tujuan kajian ini adalah untuk mengenal pasti perkaitan antara tahap kemurungan, kesihatan mental, kesan sokongan sosial dan kesejahteraan psikologi di kalangan mangsa rogol dengan aspek demografik. Subjek kajian seramai 30 wanita telah dipilih dari Pusat Perlindungan dan Pemulihan Wanita, di Batu Caves, Selangor. Kaedah ujian yang digunakan terdiri daripada Beck Depression Inventory, General Health Questionnaire-28, Provision Social Relation dan soalan demografik. Soalan diedarkan di kalangan mangsa diikuti dengan penerangan ringkas ke atas kaedah ujian. Analisis data menunjukkan terdapat perbezaan yang signifikan di antara faktor umur dan kesejahteraan psikologi mangsa (p = 0.004). Selain itu, kemurungan didapati mempengaruhi secara signifikan ke atas kesihatan mental (R' = 0.60, [F (1, 27) = 40.312, p < 0.0011). Kajian inijuga mendapati hubungan yang positif antara kesihatan mental dan kemurungan (r = 0.77). Ini bermaksud semakin tinggi kemurungan yang dialami mangsa, semakin tinggi kesan ke atas kesihatan mentalnya.
Pseudomonas sp. strain SS22 telah dipencilkan daripada kolam oksidasi kilang minyak kelapa sawit di Malaysia. Dalam kajian ini, keupayaaan bakteria ini mentransformasikan asid oleik kepada produk baru telah dikaji. Produk biotransformasi dianalisis dengan kromatografi lapisan nipis (KLN), kromatografi gas (KG), spektroskopi inframerah gandingan fourier (SIGF) dan kromatografi gas-spektrometri jisim (KG-s.1). Analisis KLN menunjukkan bahawa hanya satu produk baru terbentuk selepas 7 hari eraman pada suhu 37°C, goncangan pada 150 ppm. Semakin lama eraman menyebabkan pengurangan titik produk pada 14 harL Analisis KG menunjukkan bahawa 5 puncak produk baru pada masa penahanan 13.1(*A), 15.0 (*C), 15.3 (*D), 16.8 (*E) dan 18.4 (*F) minit telah terbentuk selepas 7 hari eraman. Spektrum inframerah (Im) bagi produk yang terbentuk daripada asid oleik selepas 7 hari, menunjukkan kewujudan regangan OH/NH pada 3417 cm-'. Serapan pada 2673 cm-', kemungkinan regangan CH bersama-sama dengan kumpulan karbonil. Serapan pada 1712 cm-' adalah konstan dengan regangan c=o daripada keton atau asid karboksilik. Regangan CH pada 2932, 2854, 1462 dan 1379 cm-1 merupakan kumpulan alkil, menandakan produk hidrokarbon juga wujud dalam produk campuran. Kehadiran CH/C-C pada serapan 969 dan 725 cm-', menandakan kewujudan alkena trans (C=C). Analisis KG-SJ mengesahkan bahawa produk tersebut merupakan campuran asid 9(E)- heksadekenoik, asid kaprilik, asid miristik dan hidrokarbon. Walaupun produk yang terbentuk bercampur, asid 9(E)-heksadekenoik boleh digunakan sebagai komponen membran lipidnya. Penghasilan produk tersebut boleh dipertingkatkan dengan mengoptimumkan keadaan pertumbuhan.
The objective of this study was to determine the Immunoglobulin E-binding proteins (IgE) and major allergens of Scomberomorus commerson Lacepede (Narrow-barred Spanish mackerel). Allergen extracts were obtained from uncooked and cooked fish by homogenization in phosphate-buffered saline followed by continuous extraction at 4oC or on ice. Protein profiles and IgEbinding patterns were then detected by means of sodium dodecyl polyacrylamide gel electrophoresis (SDS PAGE) and immunoblotting using sera from patients sensitized to the fish. SDS-PAGE of the uncooked fish extracts revealed 26 protein bands in the range of about 11 to >175 kD, while the cooked extracts produced fewer protein bands. Immunoblotting demonstrated 17 IgE-binding bands, ranging in molecular weight from 11 to 151 kD. Two components with molecular weight of about ~50 and 42 kD showed the highest frequency of IgE-binding (62.2 and 51.4% respectively) and were identified as the major allergens of this fish allergy. Other IgE-binding proteins including a protein at ~12 kD which was equivalent in size to parvalbumin were identified as the minor allergens.
This study was conducted to evaluate the oxidative damage in diabetic mellitus induced rats. The evaluation of DNA damage was carried out by the Alkaline Comet Assay using peripheral lymphocyte cells taken from streptozotocin-induced diabetic rats (50 mg/kg) and control rats. The levels of malondealdehyde (MDA), 4-hydroxynonenal (4-HNE), fasting blood glucose (FBG) and HbA1c were also measured. All the induced diabetic rats were hyperglycemic until the end of the study with significantly higher levels of FBG and HbA1c as compared to the control rats. The results showed the percentage of tail DNA and tail moment values were also significantly higher in the diabetic induced rats. The same observations were made on the levels of plasma MDA and 4-HNE. In conclusion, this study indicated that hyperglycemic condition in diabetic induced rats could generate oxidative DNA damage.
This study was carried out to compare the rate of burn wound healing with the applications of the latex of Carica papaya Linn. (papaya) or of silver sulfadiazine cream (SSD). Partial and full thickness burn wound (2 cm x 2 cm) was induced on the dorsal part of anaesthetized rats by using heated metal plates. The rats were divided into three groups, i.e. untreated group and groups treated daily with SSD and papaya latex, respectively. A digital camera was used to take photographs of the burn wounds daily to monitor their healing. It was found that there was no significant difference in the healing time of papaya latex treated group compared to the SSD treated group. Papaya latex contained digestive enzymes which might clean burn wounds but might also cause wound bleeding in a few rats of the papaya latex group.