Displaying publications 41 - 60 of 141 in total

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  1. Fulltext Evaluation of Khat (Catha edulis) Use as a Risk Factor of Cancer: A Systematic Review
    Chong ZX, Ho WY, Yan P, Alshagga MA
    Asian Pac J Cancer Prev, 2020 Apr 01;21(4):881-895.
    PMID: 32334447 DOI: 10.31557/APJCP.2020.21.4.881
    BACKGROUND: Conducting systematic review to evaluate plant use as a risk factor to cancer could be challenging. A systematic and well-balanced method should be applied to accommodate in vivo and in vitro studies to make a final decision. In this article, khat, a recreational plant used in some Arabic and African regions, was employed as an example to systematically determine its relationships to the premalignant and cancerous conditions.

    METHODS: Systematic database search was performed to recruit original human, animal or in vitro studies on khat and cancer. Sixteen studies fulfilled the inclusion criteria and subjected to assessment using Risk of Bias (RoB). Office of Health and Translation (OHAT) approach was used to rate the confidence level in the body of evidence. The evidence was integrated to establish the relationships between khat, premalignant conditions and cancer.

    RESULTS: Seven out of eight studies showed that khat causes premalignant oral lesions with moderate evidence level. Four studies showed that khat causes cancer with low evidence level and another three studies showed that khat has anti-cancer effect with moderate to high evidence level. Only one study suggested that khat is unrelated to cancer.

    CONCLUSION: RoB and OHAT approach are reliable systematic tools to evaluate plant risk to cancer and provide objective and uniform summary regardless of the study type. In conclusion, our pooled analysis did not find a direct relationship between khat and cancer but anti-cancer effect would require to be proofed on human studies.

    Matched MeSH terms: Evaluation Studies as Topic
  2. Simple high-performance liquid chromatographic method for the determination of ranitidine in human plasma
    Wong CF, Peh KK, Yuen KH
    J Chromatogr B Biomed Sci Appl, 1998 Oct 23;718(1):205-10.
    PMID: 9832378
    A simple high-performance liquid chromatographic method was developed for the determination of ranitidine in human plasma. Prior to analysis, ranitidine and the internal standard (metoprolol) were extracted from alkalinized plasma samples using dichloromethane. The mobile phase was 0.05 M potassium dihydrogenphosphate-acetonitrile (88:12, v/v) adjusted to pH 6.5. Analysis was run at a flow-rate of 1.3 ml/min and at a detection wavelength of 229 nm. The method is sensitive with a detection limit of 1 ng/ml at a signal-to-noise ratio of 3:1, while the quantification limit was set at 15 ng/ml. The calibration curve was linear over a concentration range of 15-2000 ng/ml. Mean recovery value of the extraction procedure was about 90%, while the within-day and between-day coefficients of variation and percent error values of the assay method were all less than 15%.
    Matched MeSH terms: Evaluation Studies as Topic
  3. Heroin dependence in developing countries: WHO collaborates in treatment evaluation studies
    WHO Chron, 1980 Feb;34(2):60-2.
    PMID: 6445134
    Matched MeSH terms: Evaluation Studies as Topic
  4. Critical appraisal of methodological quality of Systematic Reviews and Meta-analysis in Paediatric Dentistry journals
    Jayaraman J, Nagendrababu V, Pulikkotil SJ, Innes NP
    Int J Paediatr Dent, 2018 Nov;28(6):548-560.
    PMID: 30070003 DOI: 10.1111/ipd.12414
    OBJECTIVE: To systematically assess the methodological quality of Systematic Reviews (SRs) and Meta-Analyses (MA) published in Paediatric Dentistry journals and to analyse the relationship between the authors, journals, country, review topic, and the year of publication to the methodological quality of SRs and MA.

    DESIGN: Paediatric Dentistry journals ranked in the top five of the h5 index of Google Scholar Metrics were selected. SRs with MA were searched independently by two reviewers using PubMed and Scopus databases until December 2017. Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews (AMSTAR) tool. Statistical significance was set at P 

    Matched MeSH terms: Evaluation Studies as Topic
  5. Preliminary field evaluation of the combined adulticidal, larvicidal, and wall residual activity of ULV-applied bifenthrin against mosquitoes
    Lee HL, Khadri MS, Chiang YF
    J Vector Ecol, 1997 Dec;22(2):146-9.
    PMID: 9491365
    The combined adulticidal, larvicidal, and wall residual activity of ULV-applied bifenthrin, a synthetic pyrethroid, was evaluated in houses in Kuala Lumpur, Malaysia, against larvae and adults of lab-bred Aedes aegypti and Culex quinquefasciatus. A portable ULV sprayer was used to disperse a ULV formulation of bifenthrin at a discharge rate of 45 ml/min. The results indicated that bifenthrin sprayed at this rate exhibited all the three activities against the test mosquitoes. Complete adult mortalities were achieved, while very high larvicidal activity was also effected, which persisted for seven days. Wall bioassay with adults of Ae aegypti also resulted in very high mortality, which also persisted for one week. The combined mosquitocidal activities of bifenthrin is considered more effective especially in the control of dengue vectors.
    Matched MeSH terms: Evaluation Studies as Topic
  6. Field evaluation of Vectobac G, Vectobac 12AS and Bactimos WP against the dengue vector Aedes albopictus in tires
    Sulaiman S, Pawanchee ZA, Wahab A, Jamal J, Sohadi AR
    J Vector Ecol, 1997 Dec;22(2):122-4.
    PMID: 9491362
    The efficacy of three formulations of Bacillus thuringiensis var. israelensis was studied against Aedes albopictus in discarded tires. The formulations were: Vectobac G (corn cob formulation), Vectobac 12AS (aqueous suspension), and Bactimos WP (wettable powder formulation). Both Vectobac G and Vectobac 12AS were effective for 24 hr with more than 80% mortality. Both Vectobac formulations were significantly more effective than Bactimos WP for 24 hr after treatment (P < 0.0005). A week after treatment, Vectobac 12AS was significantly different than Bactimos WP (P < 0.05). However, Vectobac G did not differ significantly from Bactimos WP (P > 0.05); two weeks after spraying there was no significant difference among the various formulations (P > 0.05).
    Matched MeSH terms: Evaluation Studies as Topic
  7. Fulltext Effectiveness of the use of internet search by third year medical students to establish a clinical diagnosis
    Nalliah S, Chan SL, Ong CL, Suthan TH, Tan KC, She VN, et al.
    Singapore Med J, 2010 Apr;51(4):332-8.
    PMID: 20505913
    Internet search has been the main source for information and data mining in medical research. Its use by medical students has immensely contributed to learning activities. The main aim of the study was to determine the effectiveness of internet use by medical students during their initial years of clinical instruction in order to establish a diagnosis after being provided with the history and physical findings of a clinical problem.
    Matched MeSH terms: Evaluation Studies as Topic
  8. Competency-based training of health professions teachers in seven developing countries
    Vanderschmidt L, Massey JA, Arias J, Duong T, Haddad J, Noche LK, et al.
    Am J Public Health, 1979 Jun;69(6):585-90.
    PMID: 443499
    Matched MeSH terms: Evaluation Studies as Topic
  9. Accessibility of breast and cervical cancer services in Malaysia
    Arrows Change, 1997 Dec;3(3):3.
    PMID: 12294552
    Matched MeSH terms: Evaluation Studies as Topic*
  10. Building a (UN) condom manufacturing plant for social marketing projects
    Yonese T
    Integration, 1994 Dec.
    PMID: 12319132
    Matched MeSH terms: Evaluation Studies as Topic*
  11. Singapore's foreign workforce: some reflections on its benefits and costs
    Stahl CW
    Int Migr Rev, 1984;18(1):37-49.
    PMID: 12312927
    "This article provides some empirical information pertaining to the benefits and costs of foreign labor to Singapore and subjects to critical analysis some of Pang and Lim's hypotheses concerning the costs of labor importation presented in a previous article.... The article concludes with a discussion of the real cost to Malaysia of Singapore's labor importation policies and its potential for disruption of Malaysia's development plans."
    Matched MeSH terms: Evaluation Studies as Topic*
  12. Three IFRP studies investigate breast-feeding and contraception
    Netw Res Triangle Park N C, 1981 Apr;2(3):1-2.
    PMID: 12281266
    PIP:
    The International Fertility Research Program is carrying out several studies focused on breastfeeding's contraceptive protection. A longitudinal study is investigating the relationship between breastfeeding and the return of ovulation and fertility after childbirth. The impact of factors such as the early introduction of supplementary foods, resumption of menses, and sexual practices on the return of ovulation will be analyzed. The study, which will be conducted at 4 geographic sites, will include a total of 100 women who are breastfeeding and a control group of 40 nonlactating mothers. Its ultimate goal will be to determine the optimum time for breastfeeding women with different cultural needs to start using contraceptives. A second study will seek to determine whether progestogen-only oral contraceptives (OCs) have advantages for lactating women. Trials in India, Malaysia, Argentina, and Egypt will compare 1000 lactating women who use progestogen-only OCs with an equal number of women who use nonhormonal contraception in terms of contraceptive acceptance and side effects and infant weight gain. The third study will survey breastfeeding patterns in relation to changing child spacing trends in a sample of 4000 women from Lagos, Nigeria. Analyzed will be the proportions of women who are using a modern method of fertility control, the proportions protected from unwanted pregnancy by the traditional practices of prolonged breastfeeding and sexual abstinence, and determinants of recent changes in the prevalence and duration of breastfeeding.
    Matched MeSH terms: Evaluation Studies as Topic*
  13. Study findings on evaluation of integrated family planning programme performance
    Asian Pac Popul Programme News, 1980;9(1-2):10-1.
    PMID: 12262020
    PIP: In 1976 the United Nations's Economic and Social Commission for Asia and the Pacific launched a comparative study on integrated family planning programs in a number of countries in the region. In November 1979 the study directors from the participating countries meet in Bangkok to discuss the current status of the studies in their countries. The Korean and Malaysian studies were completed, the Bangladesh study was in the data collecting phase, and the Pakistani research design phase was completed. The meeting participants focused their attention on the findings and policy implications of the 2 completed studies and also discussed a number of theorectical and methodological issues which grew out of their research experience. The Malaysian study indicated that group structure, financial resources, and the frequency and quality of worker-client contact were the most significant variables determining program effectiveness. In the Korean Study, leadership, financial resources, and the frequency and quality of contact between agencies were the key variables in determining program effectiveness. In the Malaysian study there was a positive correlation between maternal and child health service performance measures and family planning service performance measures. This finding supported the contention that these 2 types of service provision are not in conflict with each other but instead serve to reinforce each other. Policy implications of the Korean study were 1) family planning should be an integral part of all community activities; 2) family planning workers should be adequately supported by financial and supply allocations; and 3) adequate record keeping and information exchange procedures should be incorporated in the programs.
    Matched MeSH terms: Evaluation Studies as Topic*
  14. Estimating impact of Malaysian family planning programme on births: a comparison of matched acceptor and non-acceptor birth rates
    Tan Boon Ann, Tey Nai Peng
    Malays J Reprod Health, 1984 Dec;2(2):111-8.
    PMID: 12280341
    Matched MeSH terms: Evaluation Studies as Topic*
  15. Laparoscopic female sterilization--an evaluation exercise in a Malaysian family planning clinic
    Kim KS, Arshat H
    Malays J Reprod Health, 1986 Jun;4(1):12-9.
    PMID: 12268568
    Matched MeSH terms: Evaluation Studies as Topic*
  16. A need-responsive programme in post-partum female sterilisation
    Arshat H
    Malays J Reprod Health, 1986 Dec;4(2):51-5.
    PMID: 12314884
    Matched MeSH terms: Evaluation Studies as Topic*
  17. A study of the acceptability and effectiveness of Norplant (R) contraceptive implants in Kuala Lumpur, Malaysia
    Arshat H, Rachagan SP, Kwa Siew Kim, Ang Eng Suan, Karim HA, Ismail MT
    Malays J Reprod Health, 1990 Jun;8(1):21-9.
    PMID: 12316341
    Matched MeSH terms: Evaluation Studies as Topic*
  18. Office laparoscopic assessment of female fertility
    Arshat H, Yuliawiratman, Piliang AS
    Malays J Reprod Health, 1983 Jan;1(1):46-54.
    PMID: 12279889
    This preliminary report details our experience and also serves to evaluate the risk benefits of office laparoscopy for female fertility assessment in 183 subjects. The patients were admitted at about 8.00 in the morning and discharged at 3.00 to 4.00 in the afternoon after laparoscopy has been performed. Only 7. 7 percent of the subjects required inhalational anesthetic gases along with a combination of intravenous sedation and local anesthetic infiltration. The pick-up rate for pelvic abnormality is fairly high, approximately 22.4 percent. Difficulties and complications encountered during laparoscopy were minimal and easily overcome. The benefits of laparoscopy overrules the risk of complications. It is suggested that all family planning clinics involved in fertility assessment and sterilization feature laparoscopy on an but patient basis as one of its main activities.
    Matched MeSH terms: Evaluation Studies as Topic*
  19. Grassroots women have their say. Programme
    Arrows Change, 1997 Aug;3(2):4-5.
    PMID: 12348425
    Matched MeSH terms: Evaluation Studies as Topic*
  20. Children as a resource: environmental degradation and fertility
    Joekes S
    Focus Gend, 1994 Jun;2(2):13-8.
    PMID: 12345527
    Matched MeSH terms: Evaluation Studies as Topic*
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