Displaying publications 41 - 60 of 3429 in total

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  1. Cheang HK, Yeung CY, Cheah I, Tjipta GD, Lubis BM, Garza-Bulnes R, et al.
    Acta Paediatr, 2022 Jul;111(7):1362-1371.
    PMID: 35340076 DOI: 10.1111/apa.16344
    AIM: To gain insight into nutritional practices and expected growth outcomes of infants born between 34 and 36 gestational weeks defined as late preterm infants (LPT).

    METHODS: An anonymous online survey among paediatricians and neonatologists from Bangladesh, Indonesia, Mexico, Nigeria, Malaysia, Singapore and Taiwan was conducted from March until October 2020. The questionnaire consisted of 40 questions on the nutritional management and expected growth outcomes of LPT in and after-hospital care.

    RESULTS: Healthcare professionals from low to high Human Development (HDI) countries (n = 322) and very high HDI countries (n = 169) participated in the survey. Human milk was the preferred feeding, resulting in an adequate growth of LPT (weight, length and occipitofrontal circumference), according to a majority of respondents (low to high HDI, 179/265, 68% vs. very high HDI, 73/143, 51%; p = 0.002). The expected growth outcome was higher after-hospital discharge. Less than half of healthcare professionals started enteral feeding during the 1st hour of life. Lactation difficulties, limited access to human milk fortifiers and donor human milk, especially among low to high HDI countries, were reported as major hurdles.

    CONCLUSION: Human milk is the first feeding choice for LPT. The diverse opinions on nutritional practices and expected growth outcomes among healthcare professionals indicate the necessity to develop general nutritional guidelines for LPT.

    Matched MeSH terms: Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature*
  2. Boo NY, Nasri NM, Cheong SK, Sivamohan N
    Singapore Med J, 1991 Apr;32(2):142-7.
    PMID: 2042076
    A 2-year study was carried out in the Maternity Hospital, Kuala Lumpur to determine the neonatal mortality rates. This Hospital functions both as the local service centre as well as the national referral centre in Malaysia. Its neonatal services, however, were equipped and manned at those below Level III perinatal centre. During the study period 52, 877 livebirths took place in the Hospital. In 1987 and 1988 respectively, the low birthweight (less than 2500 gm) rates were: 112.8 and 101.9 per 1000 livebirths, very low birthweight (less than 1500 gm) rates: 11.1 and 8.8 per 1000 livebirths, neonatal mortality rates: 12.5 and 10.7 per 1000 livebirths and neonatal mortality risk ratio: 1.15 and 1.27. There was significant difference in mortality rates among the Malay, Chinese and Indian babies born in this hospital: the Indians had the highest and the Chinese the lowest rates. Babies delivered by breech or lower segment Caesarean section (LSCS) also had significantly higher mortality than those delivered by other modes of delivery. Low birthweight neonates constituted less than 45% of the total special care nursery admission but contributed to more than 70% of the total neonatal deaths. The common causes of neonatal deaths were problems of prematurity, infection, asphyxia and congenital malformations. Preterm and low birthweight neonates died primarily from problems of prematurity or infection. Term and larger neonates died mainly from asphyxia. More than 75% of the neonatal deaths occurred before 7 days of life. Improvement of antenatal care in the community and upgrading of perinatal services in this Hospital could help to lower the morbidity and mortality due to preventable causes.
    Matched MeSH terms: Infant Mortality*; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature
  3. Corebima BIRV, Handono K, Barlianto W, Santosaningsih D, Rohsiswatmo R, Sulistijono E, et al.
    Med J Malaysia, 2023 Jul;78(4):458-465.
    PMID: 37518912
    INTRODUCTION: Necrotising enterocolitis (NEC) is a serious health problem primarily affects preterm and very low birthweight (VLBW) infants. However, the pathomechanism of NEC remains elusive. This study aimed to analyse the risk factors for NEC among preterm neonates in East Java, Indonesia.

    MATERIALS AND METHODS: A single-centre, prospective, casecontrol study involving 32 subjects of preterm neonates was conducted at a tertiary care hospital in Malang, East Java, Indonesia between January to June 2022. A total of 15 preterm neonates with NEC and 17 preterm neonates without NEC were enrolled in this study. Data on demographic, clinical and laboratory findings were collected. Multiple logistic regression test was performed to analyse the risk factors for NEC development. Further profiling within 15 subjects with NEC, i.e., NEC grade ≥ II, were conducted to collect systemic, abdominal, laboratory, abdominal x-ray (AXR) and blood culture findings.

    RESULTS: The risk factors related to NEC development in preterm infants were multi-morbidity (adjusted OR = 11.96; 95% CI 1.85 168.38; p = 0.046), antibiotic exposure (OR = 15.95; 95% CI 1.54 165.08; p = 0.020) and requiring advanced neonatal resuscitation at birth (OR = 10.04; 95% CI 1.09 92.11; p = 0.041). Further profiling within NEC cohorts highlighted respiratory distress (86.7%), (oro)gastric retention (80.0%), thrombocytopenia (53.3%), gastrointestinal dilatation in AXR (53.3%), and positive blood culture Klebsiella pneumoniae (40.0%) were most common findings.

    CONCLUSION: Preterm neonates with multimorbidity, prolonged antibiotic exposure, and requiring advanced resuscitation at birth were more likely to develop NEC. Early detection of the risk factors and determinant factors for survival may help to improve the clinical outcome.

    Matched MeSH terms: Infant; Infant, Newborn; Infant, Newborn, Diseases*; Infant, Premature
  4. Wong HB
    J Singapore Paediatr Soc, 1986;28(1-2):104-11.
    PMID: 3762069
    Matched MeSH terms: Infant Mortality*; Infant, Low Birth Weight*; Infant, Newborn; Infant, Newborn, Diseases/epidemiology
  5. Manderson L
    Int J Health Serv, 1982;12(4):597-616.
    PMID: 6754637 DOI: 10.2190/0A5U-GCC6-V4BU-28T5
    Considerable attention has been paid to the correlation between high infant morbidity and mortality rates and the increased incidence of bottle feeding. The shift from prolonged breast feeding to a mixed regime or the exclusive use of sweetened condensed milk or infant formula has been related to the promotional activities of milk companies, and typically has been presented as a relatively recent development in Third World countries. However, the marketing of tinned and powdered milk only partially explains the increased use of these products. In colonial Malaya, condensed milk was marketed from the late 19th century. Infant formula was available from the turn of the century and was widely advertised, first in the English-language press and later also in the vernacular presses. At the same time, other social and cultural factors served to discourage breast feeding. There were changes in ideas regarding ideal body weight for both women and infants, and regarding infant care and diet; these ideas were presented in the mass media. In addition, maternal and child health clinics, established in the 1920s to reduce the high infant mortality rate, both propagated popular beliefs about infant weight and supplied milk and educated women to artificially feed their infants. Industry, the media, and health services all promoted, if not always intentionally, bottle feeding rather than breast feeding. Bottle feeding as an ideal, if not a reality, was thus well established before the intensive promotion of milk products by multinational corporations that followed the political independence of the colony.
    Matched MeSH terms: Infant Food/supply & distribution*; Infant Mortality; Infant Nutritional Physiological Phenomena*; Infant Welfare; Infant, Newborn
  6. Rohana J, Ishak S, Wan Nurulhuda WMZ
    Pediatr Int, 2018 Aug;60(8):710-713.
    PMID: 29804322 DOI: 10.1111/ped.13605
    BACKGROUND: Preterm infants are at higher risk of sudden infant death syndrome (SIDS) compared with term born infants and the risk is inversely proportional to the gestational age and birthweight. Parents of these infants should have adequate knowledge and practise the recommended SIDS risk reduction measures.

    METHODS: A survey was conducted between December 2016 and August 2017 at Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur. Parents of preterm infants ≤36 weeks' gestation were invited to answer a self-administered questionnaire to assess their knowledge and practise regarding SIDS risk reduction.

    RESULTS: Forty-nine (61.33%) of the 80 parents had heard of SIDS prior to the interview, with social media being the commonest source of information (67.3%). Only 35 (43.7%) correctly answered at least five of nine questions on knowledge of SIDS risk reduction ("good knowledge"). When compared with the group of parents who answered less than five questions correctly ("poor knowledge"), there was no significant difference in the demographic and infant characteristics between the groups. The majority (68.8%) of parents practised bed sharing with their infants, and this was significantly more common in the group of parents with poor knowledge (P = 0.01). Household smoking was also significantly more common in the group of parents with poor knowledge (P = 0.048).

    CONCLUSION: Knowledge on SIDS risk reduction measures was generally poor among parents of preterm infants in this study. Cigarette smoking, bed sharing and non-supine sleep positions, which are associated with increased risk of SIDS, were common practise among the present subjects.

    Matched MeSH terms: Infant; Infant, Newborn; Infant, Premature*; Sudden Infant Death/etiology; Sudden Infant Death/prevention & control*
  7. Mohamed Z, Newton JM, Lau R
    Int J Nurs Pract, 2014 Apr;20(2):187-193.
    PMID: 24713015 DOI: 10.1111/ijn.12125
    This study sought to explore the impact of Malaysian nurses' perceptions, knowledge and experiences in preterm infant skin care practices using a descriptive approach. Questionnaires were distributed to Neonatal Intensive Care Unit (NICU) nurses in one teaching hospital in Malaysia. A knowledge gap was revealed among nurses in both theoretical and practical knowledge of preterm infant skin. Nurses working for more than 5 years in NICU or having a Neonatal Nursing Certificate (NNC) were not predictors of having adequate knowledge of preterm infants' skin care. The results highlight the complex issue of providing effective skin care to preterm infants. However, a specific finding related to nurses' confidence provides some direction for future practice and research initiatives. Clear clinical evidence-based guidelines and Continuing Nursing Education on relevant topics of preterm infants' care may provide the required knowledge for the nurses.
    Matched MeSH terms: Infant, Newborn; Infant, Premature*
  8. Boo NY, Lim SM, Koh KT, Lau KF, Ravindran J
    Med J Malaysia, 2008 Oct;63(4):306-10.
    PMID: 19385490 MyJurnal
    This study aimed to identify the risk factors which were significantly associated with low birth weight (LBW, <2500 g) infants among the Malaysian population. This was a case-control study carried out at the Tuanku Jaafar Hospital, Seremban, Malaysia over a five-month period. Cases were all infants born with birth weight less than 2500 g. Control infant were selected with the help a random sampling table from among infants with birth weight of > or =2500 g born on the same day in the hospital. Of 3341 livebirths delivered in the hospital, 422 (12.6%) were LBW infants. Logistic regression analysis showed that, after controlling for various potential confounders, the only significant risk factors associated with infants of LBW were gestational age (adjusted odds ratio (OR)=0.6, 95% C.I.: 0.5, 0.6; < 0.0001), maternal pre-pregnancy weight (adjusted OR = 0.97, 95% C.I.: 0.95, 0.99; p < 0.0001), nulliparity (adjusted OR = 3.4, 95% C.I.: 2.2, 5.1; p < 0.0001), previous history of LBW infants (adjusted OR = 2.3, 95% C.I.: 1.4, 3.8; p=0.001) and PIH during current pregnancy (adjusted OR=3.3, 95% C.I.: 1.6, 6.6; p = 0.001). A number of potentially preventable or treatable risk factors were identified to be associated with LBW infants in Malaysia.
    Matched MeSH terms: Infant, Low Birth Weight*; Infant, Newborn
  9. al-Mohdzar SA, Haque E, Abdullah WA
    Asia Oceania J Obstet Gynaecol, 1993 Dec;19(4):401-5.
    PMID: 8135673
    Hospital University Sains Malaysia (HUSM) functions as the state referral centre and the only hospital for the state of Kelantan that can offer neonatal intensive care service. The deliveries in HUSM with grand multiparity, late booking and problems of late referrals resembles a hospital serving a semiurban rather than an urban community. A comparison between the year 1989 and 1991 showed marked improvement of perinatal mortality rate from 41.32 to 24.88, which is significantly better than the improvement achieved from 1987 to 1989 (46.0 to 41.32). This was possible due to a marked fall in the early neonatal mortality rate from 10.02 in 1989 to 5.45 in 1991 and fall in the stillbirth rate from 31.61 to 19.53.
    Matched MeSH terms: Infant Mortality/trends*; Infant, Newborn
  10. Valyasevi A, Dhanamitta S
    Med J Malaysia, 1986 Mar;41(1):53-8.
    PMID: 3796351
    Matched MeSH terms: Infant; Infant Food*
  11. Latifah R, Razak IA
    J Pedod, 1989;13(4):323-7.
    PMID: 2638396
    The fluoride content of several brands of infant milk formulas were determined to approximate that available in the water used in its preparation. It was also found that the public water supply contains a mean fluoride content of 0.379 ppm. The daily fluoride intake derived from infant milk formulas in a fluoridated community is discussed in relation to the recommended dosage.
    Matched MeSH terms: Infant; Infant Food/analysis*
  12. Abidin Z, Kuhan N
    Med J Malaysia, 1984 Sep;39(3):192-6.
    PMID: 6443580
    Seven infants with birth weights less than lS00g received total parenteral nutrition for seven to 16 days through the peripheral route, commencing within the first 24 hours of life. Excessive weight loss was prevented and the infants showed significant weight gain. The time required to regain the initial birth weight showed an improvement over that expected in conventionally managed infants. Metabolic and septic complications were minimal and easily manageable. The results demonstrate that the technique, when properly used, warrants consideration in feeding low birth weight infants incapable of tolerating enteral feeding.
    Matched MeSH terms: Infant, Low Birth Weight*; Infant, Newborn
  13. Kasim MS, Paramjothy M
    J Singapore Paediatr Soc, 1987;29 Suppl 1:24-31.
    PMID: 3657092
    Matched MeSH terms: Infant; Infant Mortality*
  14. Dugdale AE, Puvan IS
    Med J Malaya, 1971 Dec;26(2):98-101.
    PMID: 4260868
    Matched MeSH terms: Infant Mortality*; Infant, Newborn
  15. Mahaq O, P Rameli MA, Jaoi Edward M, Mohd Hanafi N, Abdul Aziz S, Abu Hassim H, et al.
    Brain Behav, 2020 11;10(11):e01817.
    PMID: 32886435 DOI: 10.1002/brb3.1817
    INTRODUCTION: Edible bird nest (EBN) is a natural food product produced from edible nest swiftlet's saliva which consists of glycoproteins as one of its main components; these glycoproteins contain an abundant of sialic acid. The dietary EBN supplementation has been reported to enhance brain functions in mammals and that the bioactivities and nutritional value of EBN are important during periods of rapid brain growth particularly for preterm infant. However, the effects of EBN in maternal on multigeneration learning and memory function still remain unclear. Thus, the present study aimed to determine the effects of maternal EBN supplementation on learning and memory function of their first (F1)- and second (F2)-generation mice.

    METHODS: CJ57BL/6 breeder F0 mice were fed with EBN (10 mg/kg) from different sources. After 6 weeks of diet supplementations, the F0 animals were bred to produce F1 and F2 animals. At 6 weeks of age, the F1 and F2 animals were tested for spatial recognition memory using a Y-maze test. The sialic acid content from EBN and brain gene expression were analyzed using HPLC and PCR, respectively.

    RESULTS: All EBN samples contained glycoprotein with high level of sialic acid. Dietary EBN supplementation also showed an upregulation of GNE, ST8SiaIV, SLC17A5, and BDNF mRNA associated with an improvement in Y-maze cognitive performance in both generations of animal. Qualitatively, the densities of synaptic vesicles in the presynaptic terminal were higher in the F1 and F2 animals which might derive from maternal EBN supplementation.

    CONCLUSION: This study provided a solid foundation toward the growing research on nutritional intervention from dietary EBN supplementation on cognitive and neurological development in the generation of mammals.

    Matched MeSH terms: Infant, Newborn; Infant, Premature*
  16. Dugdale AE
    Med J Malaya, 1969 Jun;23(4):244-6.
    PMID: 4242167
    Matched MeSH terms: Infant; Infant, Newborn*
  17. Lourdenadin S
    Med J Malaya, 1969 Jun;23(4):239-43.
    PMID: 4242166
    Matched MeSH terms: Infant Mortality*; Infant, Newborn
  18. Lie-Injo LE
    Med J Malaya, 1961 Dec;16:107-14.
    PMID: 14465150
    Matched MeSH terms: Infant; Infant, Newborn/blood
  19. Balakrishnan S, bin Haji Hussein H
    Med J Malaysia, 1977 Sep;32(1):22-4.
    PMID: 609338
    Matched MeSH terms: Infant; Infant Food; Infant Nutritional Physiological Phenomena
  20. MILLIS J
    Med J Malaya, 1958 Dec;13(2):145-52.
    PMID: 13632212
    Matched MeSH terms: Infant; Infant Nutritional Physiological Phenomena*
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