Displaying publications 41 - 60 of 480 in total

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  1. Foong CC, Bashir Ghouse NL, Lye AJ, Pallath V, Hong WH, Vadivelu J
    Ann Med, 2022 Dec;54(1):195-210.
    PMID: 35019800 DOI: 10.1080/07853890.2021.1967440
    BACKGROUND: Poor academic performance and failure can cause undesired effects for students, schools, and society. Understanding why some students fail while their peers succeed is important to enhance student performance. Therefore, this study explores the differences in the learning process between high- and low-achieving pre-clinical medical students from a theory of action perspective.

    METHODS: This study employed a qualitative instrumental case study design intended to compare two groups of students-high-achieving students (n = 14) and low-achieving students (n = 5), enrolled in pre-clinical medical studies at the Universiti Malaya, Malaysia. Data were collected through reflective journals and semi-structured interviews. Regarding journaling, participants were required to recall their learning experiences of the previous academic year. Two analysts coded the data and then compared the codes of high- and low-achieving students. The third analyst reviewed the codes. Themes were identified iteratively, working towards comparing the learning processes of high- and low-achieving students.

    RESULTS: Data analysis revealed four themes-motivation and expectation, study methods, self-management, and flexibility of mindset. First, high-achieving students were more motivated and had higher academic expectations than low-achieving students. Second, high-achieving students adopted study planning and deep learning approaches, whereas low-achieving students adopted superficial learning approaches. Third, in contrast to low-achieving students, high-achieving students exhibited better time management and studied consistently. Finally, high-achieving students proactively sought external support and made changes to overcome challenges. In contrast, low-achieving students were less resilient and tended to avoid challenges.

    CONCLUSION: Based on the theory of action, high-achieving students utilize positive governing variables, whereas low-achieving students are driven by negative governing variables. Hence, governing variable-based remediation is needed to help low-achieving students interrogate the motives behind their actions and realign positive governing variables, actions, and intended outcomes.Key MessagesThis study found four themes describing the differences between high- and low-achieving pre-clinical medical students: motivation and expectation, study methods, self-management, and flexibility of mindset.Based on the theory of action approach, high-achieving pre-clinical medical students are fundamentally different from their low-achieving peers in terms of their governing variables, with the positive governing variables likely to have guided them to act in a manner beneficial to and facilitating desirable academic performance.Governing variable-based remediation may help students interrogate the motives of their actions.

    Matched MeSH terms: Qualitative Research
  2. Chong DW, Jayaraj VJ, Ab Rahim FI, Syed Soffian SS, Azmi MF, Mohd Yusri MY, et al.
    PLoS One, 2024;19(4):e0299659.
    PMID: 38593177 DOI: 10.1371/journal.pone.0299659
    INTRODUCTION: Colorectal cancer is a growing global health concern and the number of reported cases has increased over the years. Early detection through screening is critical to improve outcomes for patients with colorectal cancer. In Malaysia, there is an urgent need to optimize the colorectal cancer screening program as uptake is limited by multiple challenges. This study aims to systematically identify and address gaps in screening service delivery to optimize the Malaysian colorectal cancer screening program.

    METHODS: This study uses a mixed methods design. It focuses primarily on qualitative data to understand processes and strategies and to identify specific areas that can be improved through stakeholder engagement in the screening program. Quantitative data play a dual role in supporting the selection of participants for the qualitative study based on program monitoring data and assessing inequalities in screening and program implementation in healthcare facilities in Malaysia. Meanwhile, literature review identifies existing strategies to improve colorectal cancer screening. Additionally, the knowledge-to-action framework is integrated to ensure that the research findings lead to practical improvements to the colorectal cancer screening program.

    DISCUSSION: Through this complex mix of qualitative and quantitative methods, this study will explore the complex interplay of population- and systems-level factors that influence screening rates. It involves identifying barriers to effective colorectal cancer screening in Malaysia, comparing current strategies with international best practices, and providing evidence-based recommendations to improve the local screening program.

    Matched MeSH terms: Qualitative Research
  3. Lyu FF, Ramoo V, Chui PL, Ng CG
    Clin Nurs Res, 2024 Jan;33(1):40-50.
    PMID: 37970808 DOI: 10.1177/10547738231198561
    Exercise is significantly beneficial for patients with osteoporosis. However, physiological and psychological factors such as pain and kinesiophobia prevent patients from participating in exercise. Therefore, it is important to understand how these patients perceive participation in exercise. This qualitative study was conducted in China using conventional content analysis. Using a purposeful sampling method, 17 patients with primary osteoporosis were recruited. Data were collected through a semi-structured interview and managed using ATLAS.ti 21. Nine generic categories were developed from 26 subcategories and two main categories were identified: Barriers and facilitators, support systems, network resources, positive emotions, and reactions were the facilitators for exercise in this study. In addition, mindful exercise was positively viewed by the patients. Inefficient awareness, weak support systems, and burdens were identified as barriers. To improve compliance in clinical practice, targeted exercise protocols should be developed for patients based on these perceptions.
    Matched MeSH terms: Qualitative Research
  4. Masood M, Thaliath ET, Bower EJ, Newton JT
    Community Dent Oral Epidemiol, 2011 Jun;39(3):193-203.
    PMID: 21070318 DOI: 10.1111/j.1600-0528.2010.00584.x
    To appraise the quality of published qualitative research in dentistry and identify aspects of quality, which require attention in future research.
    Matched MeSH terms: Qualitative Research*
  5. Wong LP
    PLoS One, 2012;7(12):e51745.
    PMID: 23272156 DOI: 10.1371/journal.pone.0051745
    BACKGROUND: This study was a qualitative investigation into sexual attitudes and behaviours, and contraceptive use among Malaysian youth, based on constructs from the health belief model, theory of reasoned action, and problem behaviour theory.
    METHODS: A total of 34 focus group discussions with 185 participants were conducted among the Malay (35%), Chinese (34%), and Indian (31%) young females between November, 2010 and April, 2011. The participants were secondary school students and university undergraduates from Selangor and the Federal Territory of Kuala Lumpur.
    RESULTS: The study found a lack of knowledge about sexual issues and contraception among the participants. Many engaged in unprotected sexual intercourse and relied on periodic abstinence, natural methods, and traditional folk pregnancy preventive practices. The findings also revealed numerous categories of factors influencing sexual attitudes and behaviours: ethnic group and religion, level of religiosity, peer pressure and norms, and parental monitoring. With regard to condom use, factors such as embarrassment about condom acquisition, low perceived susceptibility to sexually transmitted infections (STIs), and perceived efficacy of traditional and folk methods of contraception, were uncovered from the discussions.
    CONCLUSION: This study underscores the importance of development of culturally specific interventions that address the identified promoting factors of premarital sex. Behavioral interventions to promote condom use should increase awareness about condom effectiveness against not only unwanted pregnancies but also STIs.
    Matched MeSH terms: Qualitative Research*
  6. Nelwati, Abdullah KL, Chan CM
    Nurse Educ Today, 2018 Dec;71:185-192.
    PMID: 30293048 DOI: 10.1016/j.nedt.2018.09.018
    BACKGROUND: Peer learning experiences have been reported in previous qualitative studies, however individual findings could limit practical leverage due to small sample size. Thus it is necessary to integrate invaluable findings from various qualitative studies to consider appropriateness and acceptability of peer learning in professional nurse education.

    OBJECTIVE: To identify and synthesize qualitative evidence of peer learning experiences of undergraduate nursing students so as to understand their perceptions on peer learning experiences.

    DESIGN: A qualitative systematic review was conducted in accordance with the Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) statement.

    DATA SOURCES: Database searching was conducted on electronic databases such as Cumulative Index to Nursing and Allied Health Literature (CINAHL), Science Direct, and MEDLINE that published from 2007 to 2017.

    REVIEW METHODS: Qualitative studies were appraised using the Critical Appraisal Skills Programme (CASP). Thematic analysis was used to analyse the data using line by line coding, organising coding into descriptive themes, and interpreting further to generate new insights.

    RESULTS: Six studies were included in this review. The most common themes identified were integrated into two new insights including personal development and professional development.

    CONCLUSION: This review has revealed that peer learning experiences contribute to the learning process of undergraduate nursing students in preparing them to become professional nurses through personal development and professional development.

    Matched MeSH terms: Qualitative Research*
  7. Sweeney LA, Molloy GJ, Byrne M, Murphy AW, Morgan K, Hughes CM, et al.
    PLoS One, 2015;10(12):e0144074.
    PMID: 26633191 DOI: 10.1371/journal.pone.0144074
    BACKGROUND: The oral contraceptive pill (OCP) remains the most popular form of prescription contraception in many countries, despite adherence difficulties for many. Uptake of long acting reversible contraceptives (LARCs), which are less reliant on user adherence, remains low. The aim of this study was to explore the experiences of, and attitudes towards, prescription contraception amongst samples of contraception users, general practitioners (GPs) and pharmacists.
    METHODOLOGY AND FINDINGS: We conducted a qualitative study using semi-structured interviews with 18 contraception users, 18 GPs and 9 pharmacists. The study took place in Galway, Republic of Ireland between June and September 2014. Thematic analysis was used to analyse the data. Overall, contraception users were more familiar with the OCP, and all the women interviewed began their prescription contraception journey using this method. All participants identified episodes of poor adherence throughout the reproductive life course. The identified barriers for use of LARCs were lack of information, misconceptions, lack of access and high cost. In contrast, GPs believed that adherence to the OCP was good and stated they were more likely to prescribe the OCP than other methods, as they were most familiar with this option. Barriers to prescribing LARCSs were time, cost to practice, training and deskilling. Pharmacists also believed that adherence to the OCP was generally good and that their role was limited to dispensing medication and providing information when asked.
    DISCUSSION AND CONCLUSION: There are contrasting perspectives between contraception service providers and contraceptive users. Training for healthcare providers is required to support informed contraceptive choice and adherence. It is necessary to address the practice barriers of cost and lack of time, to promote better communication around adherence issues and prescription contraception options. There is a need for more easily-accessible public health information to promote awareness on all methods of prescription contraception.
    Matched MeSH terms: Qualitative Research
  8. Chew BH, Lee PY, Ismail IZ
    Malays Fam Physician, 2014;9(2):26-33.
    PMID: 25893068
    BACKGROUND: Personal mission in life can determine the motivation, happiness, career advancement and fulfilment in life of the medical students (MSs) along with improvement in professional/clinical performance of the family physicians. This study explored the personal beliefs, values and goals in the lives of MSs and general practitioners (GPs).
    METHODS: Fourth-year MSs at the Universiti Putra Malaysia and GPs who participated in a 2-hour session on 'Ethics in Family Medicine' in 2012 were invited. All the participants submitted the post-session written reflections about their personal missions in life. The written reflections were analysed using thematic analysis.
    RESULTS: A total of 87 MSs and 31 GPs submitted their written reflections. The authors identified 17 categories from the reflections contained by four themes-good vs. smart doctor, professional improvement vs. self-improvement, self-fulfilment and expressed motivation. The most common categories were "to be a good doctor" (97/330) and "professional improvement" (65/330). Many MSs had expressed motivation and wanted to be a smart doctor as compared to the GPs, whereas a larger number of GPs wished to have a fulfilled life and be a good doctor through professional improvement.
    CONCLUSION: The difference between the two student groups might indicate different levels of maturity and life experiences. Medical teachers should engage students more effectively in orientating them towards the essential values needed in medical practice.
    KEYWORDS: Concept formation; education; goals; medical; medical students general; practitioners; professional; values of life
    Matched MeSH terms: Qualitative Research
  9. Syed IA, Syed Sulaiman SA, Hassali MA, Lee CK
    Health Expect, 2015 Oct;18(5):1363-70.
    PMID: 24010818 DOI: 10.1111/hex.12116
    BACKGROUND: Health-related quality of life (HRQoL) is increasingly recognized as an important outcome and as a complement to traditional biological end points of diseases such as mortality. Unless there is a complete cure available for HIV/AIDS, development and implementation of a reliable and valid cross cultural quality of life measure is necessary to assess not only the physical and medical needs of HIV/AIDS people, but their psychological, social, environmental, and spiritual areas of life.
    METHODS: A qualitative exploration of HIV/AIDS patients' understanding, perceptions and expectations will be carried out with the help of semi structured interview guide by in depth interviews, while quantitative assessment of patient reported adverse drug reactions and their impact on health related quality of life will be carried out by using data collection tool comprising patient demographics, SF-12, Naranjo scale, and a clinical data sheet.
    RESULTS/OUTCOMES: The findings may serve as baseline QOL data of people living with HIV/AIDS in Malaysia and also a source data to aid construction of management plan to improve HIV/AIDS patients' QOL. It will also provide basic information about HIV/AIDS patients' perceptions, expectations and believes towards HIV/AIDS and its treatment which may help in designing strategies to enhance patients' awareness which in turn can help in addressing issues related to compliance and adherence.
    KEYWORDS: HIV/AIDS; adverse drug reactions; patients' perspective; quality of life
    Matched MeSH terms: Qualitative Research
  10. Tan BY, Shafie AA, Hassali MA, Saleem F, Kumar R
    Value Health, 2015 Nov;18(7):A831.
    PMID: 26534439 DOI: 10.1016/j.jval.2015.09.317
    Objectives: Medication adherence to treatment recommendations has major impact on health outcomes. Numerous interventions to improve medication adherence among the patients have been studied in clinical trials, including calendar packaging and patient reminder letters. Therefore, this study is aimed to explore hypertensive patient’s perceptions towards calendar packaging and its impact on medication adherence.
    Methods: A qualitative method was adopted, whereby two focus group sessions were conducted among 16 conveniently sampled hypertensive patients from a community based non-governmental organisation in the state of Penang, Malaysia. A pre validated focus group guide was constructed and used for data collection. Collected data was transcribed verbatim and analysed by thematic content analysis to identify the emerging themes.
    Results: Each focus group consisted of 8 hypertensive patients. Thematic content analysis resulted into 3 major themes (knowledge and familiarity with the medicines names and their packaging; perception about the packaging and labelling of medicines; knowledge and views of calendar packaging) and each theme was further divided into 2 sub themes. Majority of the hypertensive patients were not familiar with their medication names, however they were able to identify their medications based on the appearance and packaging. Participants agreed that calendar packaging is a great intervention to increase awareness among patients about regular medicine use and increase medication adherence.
    Conclusions: The study concluded that hypertensive patients relied on the packaging and labelling on the medications to identify their medications. Thus, packaging and labelling of the medications play an important role in improving medication adherence and reduce medication errors. This finding can help to enhance the drug manufacturers to pay attention on the drug packaging in order to increase medication adherence among the patients.
    Matched MeSH terms: Qualitative Research
  11. Razali S, Kirkman M, Fisher J
    Child Abuse Review, 2020;29:73-84.
    DOI: 10.1002/car.2573
    Although filicide is discussed with concern in the print media and online in Malaysia, there is little empirical evidence about its aetiology or appropriate responses. We sought to elucidate the opinions of health, social work, education and policy professionals in Malaysia on the causes of, and solutions to, filicide. Fifteen informants participated in semi-structured qualitative interviews. Informants attributed responsibility for filicide to girls and women as a consequence of their failure to comply with social norms and religious teachings; the stigmatised social position of women who are pregnant and unmarried was identified as a contributing factor. No informant mentioned the impact of gender-based violence, including sexual violence against girls and women. Informants' views reflect the dominant discourse of filicide in Malaysia, which is that it results from women's failure to adhere to Malaysian norms of morality, religion, customs and traditions. Solutions were largely directed at changing the behaviour of girls and women. Given the disparities between the public discourse and evidence of the experiences of women convicted of filicide, interventions that promote social change might be more effective than strategies targeting women. ‘We sought to elucidate the opinions of health, social work, education and policy professionals in Malaysia on the causes of, and solutions to, filicide’. ‘Filicide is generally agreed to denote the crime of a parent killing her or his child aged up to 18 years’. Key Practitioner Messages: There are adverse consequences for children and women in Malaysia when responsibility for child safety is placed on individual women and not referred to a society structured on strict gender roles and masculine power. Practitioners in Malaysia would benefit from international support to understand the effects of marginalised women's experiences. © 2020 John Wiley & Sons, Ltd.
    Matched MeSH terms: Qualitative Research
  12. NURUL ASIKIN ISMAIL, MOHHIDIN OTHMAN, M. SHAHRIM AB KARIM
    MyJurnal
    This study was conducted to identify the practices of Malay chefs in preparing traditional Malay dishes at hotels in the Klang Valley. In addition, this study aimed to identify the level of knowledge and practices of these chefs with regard to traditional cooking and to analyse how the knowledge could be passed on to the younger generation of Malay chefs. In reality, these practices and traditions which include the practices in food preparation, skills and cooking techniques to maintain the authenticity and sustainability of the traditional Malay cuisine are slowly being neglected, especially among those in the hotel industry. The younger generation of Malay chefs no longer seems to take pride in the traditional way of cooking. In addition, the use of processed food in Malay kitchens is very common today. In order to achieve the aims of the study, a qualitative research was conducted. Chefs at various hotels in the Klang Valley were interviewed to determine their current practices. The findings showed that the techniques of cooking traditional Malay foods have been tainted with modern culinary techniques due to a lack of exposure and knowledge in traditional Malay cuisine. In general, traditional cooking methods are viewed as outdated, obsolete and not in accordance to modernisation. By conforming to the style of cooking with modern equipment and technology, this has indirectly altered the prevailing practices of the traditional food preparation in hotels.
    Matched MeSH terms: Qualitative Research
  13. NURUL HIDAYAH ZULKIPLI, SURIA BABA
    MyJurnal
    The problem in analysing qualitative study is regularly highlighted when it comes to data analysis process. Unlike quantitative data that deals with numerical and statistical issues, analysing qualitative data requires the researcher to deal with understanding human experiences and interpreting the data. Therefore, validity and reliability of the analysis are often questioned and becomes a challenge in analysing data from qualitative research. The objective of this writing is to highlight some of the challenges and strengths in the qualitative research process. Validity, reliability, and credibility are among the challenges in analysing qualitative study. Rigor in conducting data collection helps in overcoming the problem in validity, reliability and credibility. In addition, in-depth understanding and triangulation techniques such as interview, document analysis and observation used in qualitative researches are among the strengths for qualitative study.
    Matched MeSH terms: Qualitative Research
  14. Ling TW, Khuan L, Baharom A, Arshad MM
    Nephrol Nurs J, 2021 3 9;48(1):31-48.
    PMID: 33683842
    The purpose of this literature review was to explore the qualitative evidence on coping strategies used by patients with end stage kidney disease (ESKD) to manage the challenges and outcomes associated with the condition. A systematic review design following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines was used, and a thematic analysis was used to analyze the data. Four themes were identified from the 14 selected studies: external support, emotion management strategies, reliance on faith or spirituality, and self-care practices. Implications of these findings are discussed. Further primary qualitative studies using interviews and focus groups are needed to gain additional in-depth evidence of ESKD-related coping strategies.
    Matched MeSH terms: Qualitative Research
  15. Juliasih NN, Soedarsono, Sari RM
    Infect Dis Rep, 2020 07 07;12(Suppl 1):8728.
    PMID: 32874460 DOI: 10.4081/idr.2020.8728
    Background: This study discusses the analysis of Tuberculosis (TB) program management at the Perak Timur Primary Health Care (PHC) and the Sawahan PHC in Surabaya. Early detection and adequate treatment can prevent transmission and improve control programs.

    Objective: This study aims to analyze management of the tuberculosis program at PHCs in Surabaya.

    Methods: The research method used is qualitative research. Data collection was done by interviewing tuberculosis officers about TB program and carrying out observations at the PHCs.

    Results: The study showed that case finding in the Perak Timur PHC and the Sawahan PHC was passive-active. The Perak Timur PHC has facilities for rapid molecular testing, while the Sawahan PHC have to go to a center for Health Laboratory if rapid molecular testing is needed. In terms of treatment, patients at the Perak Timur PHC would come according to an agreement with TB officer, while at the Sawahan PHC, patients have to come every Monday. Officer at the Perak Timur PHC tended to accommodate the needs of TB patients compared to officer at the Sawahan PHC. The level of adherence to taking medication in two PHCs is good but there are a number of patients who have not really understood the frequency of taking medication.

    Conclusion: Generally, both PHCs have good TB program management but the Perak Timur PHC tends to be more flexible towards patients while the Sawahan PHC tends to be stricter towards patients.

    Matched MeSH terms: Qualitative Research
  16. Mairami FF, Warren N, Allotey PA, Reidpath DD
    Disabil Rehabil, 2020 11;42(22):3189-3198.
    PMID: 30950658 DOI: 10.1080/09638288.2019.1588399
    Purpose: A stroke is a sudden event which may leave individuals and their families ill-prepared to deal with the resultant disability. Several contextual factors can influence the recovery process. These factors, internal and external, exist interactively in the lived experiences of the survivors. The limited availability of rehabilitation centres that are located in urban centres meant that recovery predominately occurred outside of the biomedical health and instead relied upon the resources available to individuals and their families.Methods: A qualitative approach with data from in-depth interviews and observations were used to identify contextual factors that shaped recovery following stroke in a community. Twenty-seven individuals with stroke were drawn from a health and demographic surveillance system in Malaysia.Results: Hope and optimism, coping strategies, motivation and support from family and friends, and the use of alternative and complementary medicine shaped the process of recovery within a context where infrastructure is extremely limited.Conclusion: The identification of factors that facilitate the recovery process provides a background in which health care providers can utilise to improve their understanding of the stroke experience. Such understanding could be instrumental in aiding health professionals to offer the most effective help to their clients.Implications for rehabilitationIdentification of contextual factors provides a background for the understanding of the stroke experience.Incorporation of religion into rehabilitation could support and maintain hope in recovery for the survivors and aid acceptance.A collaboration of healthcare professionals with traditional medicine therapists may prove beneficial for the rehabilitation of stroke survivors in Malaysia.
    Matched MeSH terms: Qualitative Research
  17. MONICA LIAW KAH PEI, MARY FATIMAH SUBET
    MyJurnal
    In the Chinese community, patriotism had been a strong sentiment, but this sentiment had not been shown openly among the Chinese. Thus, this article aimed to identify the patrotic sentiments of the Chinese community in the Malay poems by applying relevance theory pioneered by Sperber and Wilson (1986). This is a qualitative study. Three poems written by Lim Swee Tin (LST), a famous Malaysian poet were analysed. Poetic lines in the poems that manifested the patriotic sentiments were identified from corpora and they were further analysed with relevance theory. Findings of the study showed that data consisting the patriotic sentiments practised by the Chinese were identified in LST’s poems. The results also showed that there were implicit meanings behind the data analysed and the implied meanings and messages had been found to be in relevance with the values and cultures practised in the Chinese community. Not only that, the study also highlighted the importance of relevance theory in analysing the data as results obtained were more theoretical, academic and of high validity. Thus, the results obtained were not only undisputed, but it also an add-on to the existing facts, understanding and knowledge to the Chinese community particularly on the culture of Chinese community.
    Matched MeSH terms: Qualitative Research
  18. RUSSEL DUNDANG ANAK JEFFREY, MARY FATIMAH SUBET
    MyJurnal
    The use of proverbs in Iban community illustrates that the community exercise language politeness in giving reproach, advice or insinuation to others. The elements used in the proverbs also reflect and describe the culture of this community by applying their experiences and observations to the environment. This study is conducted to analyze the natural elements in Ibans’ proverbs using inquisitive semantic analysis. This research is based on two objectives, namely listing and identifying Ibans’ proverbs (jaku' sempama) which contain elements of nature in the creation and to analyzing the mind and philosophy of Iban community in the creation of proverbs (jaku' sempama) by using inquisitive semantics as the theoretical framework. The natural elements identified are divided into 4 domains, namely animals, plants, resources or energy, and the universe. This is a qualitative research. Corpus data is gathered and two informants were interviewed. The meanings of the proverbs, the cognitive and the philosophy behind the creation of the proverbs plus the intellects of the Iban community are incorporated to reveal the Iban ingenuity behind the creation of a particular proverb. This study also incorporated knowledge from other areas in giving answers on the use of the natural elements identified in the Iban proverbs. Findings show that there are hidden philosophy behind the creations of the proverbs and this philosophy can be attributed to the culture of the community that behold the proverbs.
    Matched MeSH terms: Qualitative Research
  19. Paskins Z, Crawford-Manning F, Cottrell E, Corp N, Wright J, Jinks C, et al.
    BMJ Open, 2020 11 03;10(11):e040634.
    PMID: 33148763 DOI: 10.1136/bmjopen-2020-040634
    OBJECTIVE: To explore the acceptability of different bisphosphonate regimens for the treatment of osteoporosis among patients, clinicians and managers, payers and academics.

    DESIGN: A systematic review of primary qualitative studies. Seven databases were searched from inception to July 2019. Screening, data extraction and quality assessment of full-articles selected for inclusion were performed independently by two authors. A framework synthesis was applied to extracted data based on the theoretical framework of acceptability (TFA). The TFA includes seven domains relating to sense-making, emotions, opportunity costs, burden, perceived effectiveness, ethicality and self-efficacy. Confidence in synthesis findings was assessed.

    SETTING: Any developed country healthcare setting.

    PARTICIPANTS: Patients, healthcare professionals, managers, payers and academics.

    INTERVENTION: Experiences and views of oral and intravenous bisphosphonates.

    RESULTS: Twenty-five studies were included, mostly describing perceptions of oral bisphosphonates. We identified, with high confidence, how patients and healthcare professionals make sense (coherence) of bisphosphonates by balancing perceptions of need against concerns, how uncertainty prevails about bisphosphonate perceived effectiveness and a number of individual and service factors that have potential to increase self-efficacy in recommending and adhering to bisphosphonates. We identified, with moderate confidence, that bisphosphonate taking induces concern, but has the potential to engender reassurance, and that both side effects and special instructions for taking oral bisphosphonates can result in treatment burden. Finally, we identified with low confidence that multimorbidity plays a role in people's perception of bisphosphonate acceptability.

    CONCLUSION: By using the lens of acceptability, our findings demonstrate with high confidence that a theoretically informed, whole-system approach is necessary to both understand and improve adherence. Clinicians and patients need supporting to understand the need for bisphosphonates, and clinicians need to clarify to patients what constitutes bisphosphonate treatment success. Further research is needed to explore perspectives of male patients and those with multimorbidity receiving bisphosphonates, and patients receiving intravenous treatment.

    PROSPERO REGISTRATION NUMBER: CRD42019143526.

    Matched MeSH terms: Qualitative Research
  20. Awaluddin SM, Ismail N, Yasin SM, Zakaria Y, Mohamed Zainudin N, Kusnin F, et al.
    Front Public Health, 2020;8:577407.
    PMID: 33384977 DOI: 10.3389/fpubh.2020.577407
    Introduction: The trends of tuberculosis (TB) treatment success rate among children in Malaysia plateaued at 90% from 2014 to 2017. Malaysia sets a higher treatment success target of 95% to be achieved in line with an affordable, accessible, and holistic approach in managing TB among children. Objective: This study aims to explore the parents' experiences and perspectives toward achieving treatment success among children who were diagnosed with TB in two districts in Selangor state, Malaysia. Methods: The study was conducted using phenomenology study design via an in-depth interview of 15 mothers who were purposively sampled from the list of pediatric TB cases in the MyTB version 2.1 database in Klang and Petaling Districts of Selangor state. The R-based qualitative data analysis package of R version 0.2-8 was used to perform the thematic analysis. Results: Two main themes were identified from this study. The first theme was trust toward the healthcare services with the subthemes of acceptance, self-efficacy, holistic care, and perceived benefits. The second theme was the motivation to take or continue medication. The subthemes were support from family, healthcare workers' (HCWs') support, the convenience of healthcare services, community support, personal strength, and child's character. Conclusion: TB treatment success for children can be achieved when parents develop trust in healthcare services and have strong motivational factors to remain steadfast in achieving a successful treatment goal. Psychosocial support should be provided to the primary caregiver who faced any difficulty, while good relationships between parents and HCWs should be maintained. These results will inform the TB program managers to strengthen the holistic approach and identify the motivational factors among parents of children with TB disease.
    Matched MeSH terms: Qualitative Research
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