Displaying publications 41 - 60 of 614 in total

Abstract:
Sort:
  1. Fulltext A review on the accuracy of bladder cancer detection methods
    Zhu CZ, Ting HN, Ng KH, Ong TA
    J Cancer, 2019;10(17):4038-4044.
    PMID: 31417648 DOI: 10.7150/jca.28989
    Background and purpose: Bladder cancer is the most common malignant tumour in the urinary system, with a high incidence and recurrence rate. While the incidence of bladder cancer has been rising in recent years, the prevalence of bladder carcinoma is showing an increasing tendency in the younger age group. There are several methods to detect bladder cancer, but different methods have varying degrees of accuracy which intrinsically depends on the method's sensitivity and specificity. Our aim was to comprehensively summarize the current detection methods for bladder cancer based on the available literature, and at the same time, to find the best combination of different effective methods which can produce a high degree of accuracy in detecting the presence of cancerous cells in the bladder. Materials and Methods: We used key word retrieval method for searching related references in English that had been indexed in PubMed and Medline. Results and Discussion: This paper discussed the different detection methods and their sensitivities/specificities as well as the advantages and disadvantages. We summarized the best identified cancer cell detection methods with higher sensitivity/specificity. Conclusion: The results of this review can positively help to identify accurate methods for detecting bladder cancer and highlight areas to be further improved for future research work.
    Matched MeSH terms: Neoplasm Recurrence, Local
  2. Effect of regional anaesthesia only versus general anaesthesia on cancer recurrence rate: A systematic review and meta-analysis with trial sequential analysis
    Ang E, Ng KT, Lee ZX, Ti LK, Chaw SH, Wang CY
    J Clin Anesth, 2020 Dec;67:110023.
    PMID: 32805685 DOI: 10.1016/j.jclinane.2020.110023
    OBJECTIVES: There is growing evidence on the influence of general anaesthesia (GA) in promoting the proliferation of cancer cells. The benefits of regional anaesthesia (RA) on cancer recurrence rate in cancer surgery remains unclear in the literature. The primary objective of this review was to examine the effect of RA on the incidence of post-operative cancer recurrence rate in cancer resection surgery.

    DESIGN: Systematic review and meta-analysis with trial sequential analysis.

    DATA SOURCES: Medline, EMBASE and CENTRAL were systematically searched from its inception until April 2020.

    ELIGIBILITY CRITERIA: All randomized control trials and observational studies comparing RA only versus GA in cancer resection surgery were included. Case report, case series and editorials were excluded.

    RESULTS: Ten retrospective observational studies (n = 9708; 4567 GA vs 5141 RA) were included for qualitative and quantitative meta-analysis. In comparison to GA, RA was not significantly associated with a lower cancer recurrence rate in cancer resection surgery (odds ratio 1.01, 95% CI 0.67 to 1.53, p = 0.95, certainty of evidence = very low). However, the trial sequential analysis for cancer recurrence rate was inconclusive. Our analysis demonstrated no significant difference between the RA and GA groups in the overall survival rate (odds ratio 1.51, 95% CI 0.65 to 3.51, p = 0.34, certainty of evidence = very low), time to cancer recurrence (mean difference 1.45 months, 95% CI -8.69 to 11.59, p = 0.78, certainty of evidence = very low), cancer-related mortality (odds ratio 1.79, 95% CI 0.57 to 5.62, p = 0.32, certainty of evidence = very low).

    CONCLUSIONS: Given the low level of evidence and underpowered trial sequential analysis, our review neither support nor oppose that the use of RA was associated with lower incidence of cancer recurrence rate than GA in cancer resection surgery.

    TRIAL REGISTRATION: CRD42020163780.

    Matched MeSH terms: Recurrence
  3. Fulltext An Unusual Presentation and Behaviour of Endometrial Stromal Sarcoma
    Adibah, I., Wan Abu Bakar, W.Y., Nik Mohamed Zaki, N.M., Nik Hazlina, N.H., Venkatesh, R.N.
    International Medical Journal Malaysia, 2006;5(2):1-4.
    MyJurnal
    Endometrial stromal sarcoma is a rare tumour of the uterus. We reported a case of a young lady with endometrial stromal sarcoma. She became pregnant while having the disease and delivered a healthy baby, her sixth, without any complication. A total abdominal hysterectomy with bilateral oopherectomy was performed subsequently. She refused any added treatment after the operation. To date, she is free of any recurrence.
    Matched MeSH terms: Neoplasm Recurrence, Local
  4. Fulltext An Unusual Presentation of a Thyroid Malignancy: A Case Report
    Irfan, M., Baharuddin, A., Ananda Dorai, A.
    International Medical Journal Malaysia, 2010;9(1):55-57.
    MyJurnal
    Patient with thyroid mass rarely presents in emergency situation. It is because the nature of the mass is that it usually increases slowly in size. Thus, any surgical intervention can be planned electively. The most common condition that necessitates urgent intervention, is upper airway compromise due to sudden rapid increase in size of the swelling. This can be due to intralesional bleeding or superimposed infection on the enlarged gland. We report a case of urgent completion thyroidectomy performed to a patient with fungating recurrent papillary carcinoma who present with bleeding from the mass externally.
    Matched MeSH terms: Neoplasm Recurrence, Local
  5. Fulltext Pattern of Presentation and Outcome of Short-term Treatment for Idiopathic Clubfoot / CTEV with Ponseti Method
    Gunalan R, Mazelan A, Lee Y, Saw A
    Malays Orthop J, 2016 Nov;10(3):21-25.
    PMID: 28553443 MyJurnal DOI: 10.5704/MOJ.1611.009
    Introduction: Congenital Talipes Equinovarus (CTEV) is a common congenital foot deformity that is associated with long term disability. Treatment with Ponseti method has been successful especially for children who present early. We conducted this study to investigate the age of presentation of children and report the early outcome. Materials: This is a retrospective study from a single institution. We included 31 patients with 45 idiopathic clubfeet and investigated problems and success rate at the end of serial casting. Results: Mean age at presentation was 4.9 months. The mean number of casting was 6 and mean duration of casting was 2.7 months. The initial success rate of 91.1%, with four feet (8.8%) diagnosed as resistant clubfoot and eventually required soft tissue surgery. With mean follow up of 14.1 months, four other feet (8.8%) developed relapse but were treated with repeat Ponseti method. Conclusion: Many CTEV patients present late for treatment. However, the Ponseti method remained effective with high initial success rate of 91.1%. Relapsed CTEV can still be treated successfully with repeat casting using the Ponseti method.
    Matched MeSH terms: Recurrence
  6. Fulltext Classification, Epidemiology And Aetiology Of Oral Recurrent Aphtous Ulceration / Stomatitis
    Zain, R.B.
    Ann Dent, 1999;6(1):-.
    MyJurnal
    The most prevalent oral mucosal lesions are aphthous ulcerations commonly referred to as canker sores. The clinical characteristic of oral recurrent aphthous ulceration/stomatitis(ORAS) is well defined and can be partly described as an oval or rounded ulcer covered by a grey-white or yellowish fibrinous exudate and surrounded by an erythematous halo. There is intense or moderate pain and the ulcers heal in about 10 - 14 days for the more common type and more than 2 weeks for the severe type. Recurrence of the ulcers occurs at intervals within a year or over several years. Variations of ORAS described above have made studies on aetiology and treatment difficult to interpret due to differing descriptions of differing diseases with similar clinical signs and symptoms and possibly differing aetiologies. A classification that was considered useful as a working model for ORAS was formulated in 1978. While the classification of ORAS had been widely accepted since 1978, the cause for ORAS is still unknown and its aetiology in general remains unclear. However, its immunopathogenesis is now becoming more clearly defined.
    Matched MeSH terms: Recurrence
  7. Fulltext Odontogenic Keratocysts in a Malaysian Population: Clinical, Radiological and Histological Considerations
    Ong, Siew Tin, Chong, Huat Siar
    Ann Dent, 1995;2(1):-.
    MyJurnal
    This paper represents a study of35casesofodontogenic keratocyst (OKC) diagnosed in a Malaysian population. The clinical, radiological and histopathological features, treatment modalities and recurrence of this lesion were analysed. There was a higher prevalence rate among Malaysian Chinese (51.42 percent), while the Malays and Indians accounted for22.86 percent and 25.72 percent respectively. The male to female ratio was 16 : 19.Age at presentation ranged from nine to 71 year,with about 70percent occurring between ages ten to 39 years. A total of40cysts were analysed. Of these, 67.5 percent occurred in the mandible and 32.5 percent in the maxilla. About 88percent of OKC presented as unilocular radiolucencies and 42.0 percent were associated with unerupted or impacted teeth. Histologically, the parakeratinized OKC was the predominant variant found (75.8 percent). The majority of caseswere treated by enucleation (85 percent), and a recurrence rate of20percent was recorded.
    Matched MeSH terms: Neoplasm Recurrence, Local
  8. Fulltext The Incidence of Malignant Infiltration in the Biopsy Tract of Osteosarcoma
    Mohana, R., Faisham, W.I., Zulmi, W., Nawfar, A.S., Effat, O., alzihan M.S.
    Malays Orthop J, 2007;1(2):7-10.
    MyJurnal
    Biopsy is a crucial step in the management of musculoskeletal sarcoma. The surgical approach to the biopsy site is important, as the tract must be removed en bloc with the tumour during limb sparing surgery so as to reduce the risk of local recurrence. The biopsy tracts of 26 osteosarcoma patients were evaluated histologically for tumour infiltration. Horizontal sections of 1 mm thickness with 2 cm radius from were evaluated from each excised biopsy tract. Five out of 26 cases (19.2%) showed positive tumour infiltration. One case (3.85%) had tumour infiltration in the pseudocapsule, two cases (7.69%) had tumour infiltration into the muscle and two other cases (7.69%) had tumour infiltration into the subcutaneous tissue. None had skin infiltration. We conclude that resection of the entire biopsy tract is indeed mandatory for surgical treatment of osteosarcoma.
    Matched MeSH terms: Neoplasm Recurrence, Local
  9. Fulltext Management of large mandibular ameloblastoma - a case report and literature reviews
    Kahairi, A., Ahmad, R.L., Wan Islah, L., Norra, H.
    Archives of Orofacial Sciences, 2008;3(2):52-55.
    MyJurnal
    Ameloblastoma is a slow growing benign tumour of the jaw and patients usually present late after the tumour achieved considerable size to cause facial disfigurement. Diagnosis mainly from tissue biopsy and characteristic findings on plain X-rays does assist in differentiating between types of ameloblastoma. The challenges in the management of this tumour are to provide complete excision as recurrence may occur in incomplete removal and also to reconstruct the bony defect in order to give reasonable cosmetic and functional outcome to the patient.
    Matched MeSH terms: Neoplasm Recurrence, Local
  10. Fulltext External factor of relapse among male drug addicts in Cure and Care Service Centre, Kuala Pilah
    Muhd Dhamir Audi Azizul, Azlina Mohd Khir, Wan Munira Wan Jaafar
    Malaysian Journal of Social Sciences and Humanities, 2018;3(2):159-168.
    MyJurnal
    Relapse is a common phenomenon among former addicts who has undergone a preventive and rehabilitation treatment program. Relaps is a condition of using drugs more than one times after stopping them for a certain period of time depending on one's resistance to a drug withdrawal syndrome. There are various factors that affect the former drug addicts became relaps. Hence, the focus of this study is to explain the external factors of relaps among adult male drug addicts in Cure and Care Service Centre, Kuala Pilah, Negeri Sembilan. This study is a qualitative research that has been using a phenomenology approach using face-to-face interviews and further observation among eight drug addicts who are undergoing rehabilitation programs at CCSC Kuala Pilah. Sample selection was done through purposive sampling techniques and data were analyzed using thematic analysis through an inductive approach that focused on coding to obtain some key themes. The result of the study indicates the external factors such as family, peer and environmental factors play a great role in influencing of relapse. In conclusion, these identified factors illustrate the external influences that cause drug addicts to relapse. Therefore, the researcher proposes a post-rehabilitation module or program done by the responsible agencies after the addicts completed the rehabilitation program as guidance for them to the right direction for efficient recovery.
    Matched MeSH terms: Recurrence
  11. Fulltext Societal conflict among relapsing male drug addicts in Cure and Care Service Centre, Kuala Pilah, Negeri Sembilan
    Muhammad Dhamir Audi Azizul, Wan Munira Wan Jaafar, Azlina Mohd Khir
    Malaysian Journal of Social Sciences and Humanities, 2018;3(3):80-91.
    MyJurnal
    This social psychology study sought to understand how the inability of former drug addicts controlling
    interpersonal conflict that occurs in the community resulted in relapse or back to their addiction. A
    qualitative phenomenological approach was taken to conduct interviews with former drug addicts that
    are participating in a rehab program in Cure and Care Service Centre, Kuala Pilah, Negeri Sembilan,
    Malaysia. Eight informants were consented and interviewed. Purposive sampling was used and
    responses were analyzed thematically. These themes included the issue of labeling drug addicts as
    convicts, isolation from the community and restricted from participating in community-based
    programs. Researcher suggests related agencies to work with rehabilitation officers in restructuring the
    rehabilitation learning module and improve the interpersonal conflict management module. Therefore,
    it is hoped that in the future, former drug addicts would be capable to manage interpersonal conflict
    and simultaneously avoid from recidivism in addiction.
    Matched MeSH terms: Recurrence
  12. A clinical comparison of atebrin-musonate with quinine bihydrochloride. (A preliminary report based on the treatment of 286 cases of acute Malaria)
    Field JW, Niven JC
    Trans R Soc Trop Med Hyg, 1936;29:647-658.
    A comparison is made between atebrin-musonate and quinine bihydrochloride in the treatment of acute malaria. 286 cases of acute malaria due to Malayan strains of P. falciparum, P. vivax, and P. malariae, were treated in alternating sequence with one or other of these drugs. The rates at which the atebrin-musonate and the quinine case groups became trophozoite-free and fever-free are contrasted in a series of graphs. It is shown that there was a tendency for trophozoites to disappear from the peripheral blood and for temperatures to fall to normal somewhat earlier among cases treated with atebrin-musonate. No toxic effects of any importance were observed (but see footnote p. 657). Evidence is recorded which suggests that the minimal effective daily dose for an adult is 0·375 gramme (= atebrin 0·3 gramme). This dose when given either intramuscularly or intravenously on two successive days effected a rapid disappearance of parasites and fever. Intramuscular administration is regarded as the method of choice. It is noted that absorption of the drug from the muscles is very rapid, and that atebrin may be demonstrated in the urine within 10 minutes of an intramuscular injection of 0·3 gramme. A method of testing for the presence of atebrin in the urine which is sensitive to over one in a million is described. It was not possible to obtain precise data regarding the permanency of cure but an analysis of cases returning to hospital within 10 weeks of discharge suggests that relapses after atebrin-musonate treatment are probably fairly common.
    Matched MeSH terms: Recurrence
  13. Primary fungal laryngitis mimicking recurrent laryngeal carcinoma
    Thomas RA, Kew TY, Mat Baki M
    BMJ Case Rep, 2022 Feb 09;15(2).
    PMID: 35140081 DOI: 10.1136/bcr-2021-245678
    A 79-year-old smoker with a background history of a treated glottic carcinoma and chronic obstructive pulmonary disease presented with progressive hoarseness, symptoms of aspiration and shortness of breath for 6 months. Examination revealed an ulcero-fungating mass over the posterior commissure of the larynx. A tracheostomy, direct laryngoscopy and biopsy of the mass was performed to secure his airway and to exclude recurrent glottic carcinoma. Reassuringly, a histopathological examination of the mass revealed numerous fungal yeast bodies. He was then treated with itraconazole for 4 weeks and was followed up as and outpatient with complete resolution and no recurrence of the disease.
    Matched MeSH terms: Neoplasm Recurrence, Local
  14. A case of tinea nigra in Britain
    Chadfield HW, Campbell CK
    Br J Dermatol, 1972 Nov;87(5):505-8.
    PMID: 4647125
    Matched MeSH terms: Recurrence
  15. Fulltext Relationship of expressed emotion with relapse of schizophrenia patients in Kelantan
    Azhar MZ, Varma SL
    Singapore Med J, 1996 Feb;37(1):82-5.
    PMID: 8783920
    The families of 83 schizophrenic patients were studied to find out the level of expressed emotion in them leading to the relapse of these patients. The patients were having more than two episodes of schizophrenia (DSM-III-R). The most salient finding was the virtual absence of high level of expressed emotion as the cause of relapse. It was found that the majority of the families (72.3%) had low expressed emotion while only 25.3% had high expressed emotion and only 2.4% families were equivocal in this respect. This finding is in contrast with various other findings in this area. The most likely explanation for this disagreement is the cultural differences between Malaysian patients and Western patients.
    Matched MeSH terms: Recurrence
  16. Fulltext Postcricoid haemangioma with laryngomalacia in infancy
    Khamalrudin N, Goh BS
    BMJ Case Rep, 2021 Apr 19;14(4).
    PMID: 33875496 DOI: 10.1136/bcr-2020-235936
    Infantile haemangioma represents a congenital vascular anomaly commonly observed in the head and neck region. Such an occurrence over the postcricoid region, however, is rather unusual. Herein, the authors report a case of a synchronous postcricoid haemangioma in a 7-week-old newborn diagnosed with severe laryngomalacia. In addition to the floppy redundant arytenoid mucosa, flexible laryngoscopy revealed a lobulated bluish mass at the postcricoid. The lesion was hyperintense on T1-weighted sequence and was enhanced with contrast, supporting the diagnosis of a haemangioma. She underwent surgical excision of the haemangioma with intralesional steroid injection. Surveillance at 6-month postoperation did not show disease recurrence.
    Matched MeSH terms: Neoplasm Recurrence, Local
  17. Fulltext A Rare Case of Basal Cell Adenocarcinoma of Parotid Gland with Intracranial Extension
    Razali MN, Mat Baki M, Kew TY, Mohamad Yunus MR
    Indian J Otolaryngol Head Neck Surg, 2019 Oct;71(Suppl 1):93-95.
    PMID: 31741939 DOI: 10.1007/s12070-017-1116-3
    Basal cell adenocarcinoma (BCAC) is a rare tumour entity. Despite its tendency to be infiltrative and destructive tumour with propensity to recur, it rarely metastasizes and long-term outcome following surgery is favourable. This paper presents a 42-year-old male with residual BCAC of parotid gland that had extended into infratemporal fossa and intracranial. The important aspect of this case is the rarity occurrence of BCAC of parotid with intracranial extension and its surgical approaches to achieve tumour clearance.
    Matched MeSH terms: Neoplasm Recurrence, Local
  18. Cystic Meningioma Masquerading as a Metastatic Tumor: A Case Report
    Ramanathan N, Kamaruddin KA, Othman A, Mustafa F, Awang MS
    Malays J Med Sci, 2016 May;23(3):92-4.
    PMID: 27418876 MyJurnal
    Cystic meningioma is a rare form of intracranial meningioma. Meningiomas are typically solid tumors but may rarely have cystic components. The diagnosis of cystic meningioma is clinically challenging as the finding of multiple intra-axial tumors, including metastatic tumors, is relatively common. We report a case of cystic meningioma initially diagnosed as a metastatic tumor from a recurrence of acute lymphoid leukemia. However, postoperative histopathological examination demonstrated an atypical meningioma.
    Matched MeSH terms: Recurrence
  19. Fulltext Parathyroid carcinoma in a 30-year-old man: a diagnostic and management challenge
    Ng SH, Lang BH
    World J Surg Oncol, 2013;11:83.
    PMID: 23566353 DOI: 10.1186/1477-7819-11-83
    Parathyroid carcinoma is a rare endocrine malignancy, accounting for less than 1% of cases of primary hyperparathyroidism. Patient-related factors such as age and sex, as well as the biological features and management of the cancer, influence mid-term and long-term survival. We report a case of a young man with an unusual presentation of parathyroid carcinoma. The patient presented with left thigh swelling, which had been present for 6 months without other symptoms of hypercalcemia. On computed tomography scan a hypodense lesion, 30 × 20 × 20 mm in size, was seen in the posterior thyroid. There was no evidence of cervical lymphadenopathy or local infiltration. On a Sestamibi scan, a hot spot was seen in the lower pole of left thyroid lobe. Cervical neck exploration was performed. The patient subsequently underwent surgery and a parathyroid tumor was excised. The tumor was adherent to the thyroid capsule, but there was no evidence of invasion. After surgery, the patient's calcium and parathyroid hormone levels normalized, but histology confirmed parathyroid carcinoma with capsular and vascular invasion. The patient was offered reoperation, but declined, and developed recurrent parathyroid carcinoma 2 years later. In this report, we aim to present the challenges in managing parathyroid carcinoma and discuss factors that might contribute to future locoregional recurrences. This case also highlighted several issues, including the challenge of ascertaining the diagnosis before surgery and the dilemma of reoperation after simple excision.
    Matched MeSH terms: Neoplasm Recurrence, Local/diagnosis; Neoplasm Recurrence, Local/surgery*
  20. Stomal recurrence after total laryngectomy: a 10-year review in Universiti Kebangsaan Malaysia Medical Center
    bte Abdul Rashid NH, Yunus MR, bte Baki MM, bte Ami M, Athar PP
    J Pak Med Assoc, 2012 May;62(5):466-9.
    PMID: 22755311
    To determine the frequency of stomal recurrence in patients following total laryngectomy in our center and to compare the frequency of previously reported risk factors such as preoperative tracheostomy, subglottic invasion and the level of lymph node metastases, with the rest of the world.
    Matched MeSH terms: Neoplasm Recurrence, Local/epidemiology*; Recurrence
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links