Displaying all 16 publications

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  1. Chaubal T, Bapat R, Wadkar P
    QJM, 2017 Aug 01;110(8):527.
    PMID: 28453856 DOI: 10.1093/qjmed/hcx090
  2. Chaubal T, Bapat R
    Am J Med, 2018 09;131(9):e371-e372.
    PMID: 29730363 DOI: 10.1016/j.amjmed.2018.04.020
  3. Chaubal T, Bapat R
    Am J Med, 2017 Dec;130(12):e533-e534.
    PMID: 28716459 DOI: 10.1016/j.amjmed.2017.06.016
  4. Chaubal T, Bapat R
    Am J Med, 2017 Nov;130(11):e493-e494.
    PMID: 28602875 DOI: 10.1016/j.amjmed.2017.05.020
  5. Chaubal T, Bapat R, Wadkar P
    QJM, 2017 Dec 01;110(12):841-842.
    PMID: 29025105 DOI: 10.1093/qjmed/hcx164
  6. Sadaphule R, Chaubal T, Bapat R, Wadkar P
    QJM, 2017 Oct 01;110(10):685.
    PMID: 29087529 DOI: 10.1093/qjmed/hcx132
  7. Chaubal TV, Bapat R
    Am J Med, 2021 04;134(4):e270.
    PMID: 32997980 DOI: 10.1016/j.amjmed.2020.08.031
  8. Kanneppady SK, Kanneppady SS, Chaubal T, Bapat R
    QJM, 2018 Oct 01;111(10):753-754.
    PMID: 29788120 DOI: 10.1093/qjmed/hcy100
  9. Chaubal TV, Bapat R, Poonja K
    Am J Med, 2017 10;130(10):e451.
    PMID: 28528920 DOI: 10.1016/j.amjmed.2017.04.026
  10. Wei SSK, Bapat R, Chaubal T
    Am J Med, 2019 10;132(10):e737.
    PMID: 31103649 DOI: 10.1016/j.amjmed.2019.04.039
  11. Kanneppady SS, Kanneppady SK, Chaubal T, Bapat R, Pandurangappa R, Oo AM, et al.
    Am J Med, 2019 04;132(4):e538-e539.
    PMID: 30503886 DOI: 10.1016/j.amjmed.2018.11.019
  12. Tan WY, Ng JZL, Ajit Bapat R, Vijaykumar Chaubal T, Kishor Kanneppedy S
    J Prosthet Dent, 2021 May;125(5):766.e1-766.e8.
    PMID: 33752904 DOI: 10.1016/j.prosdent.2021.02.018
    STATEMENT OF PROBLEM: Lingual plate perforation can be life-threatening when vital structures are damaged during implant placement. Knowledge of the anatomy of lingual concavities is imperative for safe implant surgery.

    PURPOSE: The purpose of this clinical study was to determine the prevalence of type of posterior mandibular ridge morphology in a Malaysian population and to evaluate the buccolingual width of the alveolar ridge (Wb and Wc); alveolar ridge height (Vcb); and concavity angle, length, and depth for both left and right first and second molars in different age groups and sexes by using cone beam computed tomography (CBCT).

    MATERIAL AND METHODS: Bilateral posterior mandibular lingual concavities at the first and second molars were retrospectively studied in cross-sectional views of 150 CBCT scans (n=600 sites evaluated). The sample size was calculated at a power of 80%, confidence interval of 95%, and margin of error of .05. The buccolingual width from the base and crest of the ridge and the ridge height were measured to determine the type of ridge. For the U-shaped ridge, the concavity angle, length, and depth were assessed. The independent t test was used to compare mean values of CBCT measurements between sexes and tooth type, while the ANOVA and Pearson chi-squared test were used to determine the correlations with age groups and types of ridge morphology, respectively. To compare the left and right readings for first and second molars in the same patient, the paired t test was performed (α=.05 for all tests).

    RESULTS: The Pearson correlation showed a strong agreement between the 2 examiners with an interobserver reliability of 87.3%. Significant difference was noted in all dimensional measurements when comparing right and left first and second molars (P

  13. Lim JTS, Kang WJ, Ajit Bapat R, Kanneppady SK, Pandurangappa R
    J Maxillofac Oral Surg, 2019 Dec;18(4):596-603.
    PMID: 31624443 DOI: 10.1007/s12663-018-1168-2
    Objectives: The risk of damaging the mandibular incisive canal (MIC) during surgery in the anterior mandible should not be overlooked. Hence, preoperative radiographic assessment is essential to avoid complications. This study was aimed to estimate the length of the MIC in the interforaminal safe zone, to analyse its course in relation to the lingual and the buccal cortical plates of the mandible using cone beam computed tomography (CBCT) scans and to relate the above findings to age, gender, dental status and Malaysian races.

    Methods: Retrospective analysis of 100 CBCT scans (n = 200) was performed on both sides of the mandible. Cross-sectional and panoramic images were reconstructed. The length of the MIC and the horizontal distances between the MIC and the buccal and the lingual cortical plates were measured at the three different points (starting, mid-, end points). Independent samples t-test and one-way ANOVA test were used to analyse the variation in the length and course of the MIC in gender, age, dental status and Malaysian races.

    Results: The mean length of the MIC was 11.31 ± 2.65 mm, with the Malays having the longest MIC, followed by the Chinese and the Indians (p 

  14. Khanna D, Chaubal T, Bapat R, Abdulla AM, Philip ST, Arora S
    Afr Health Sci, 2019 Dec;19(4):3253-3263.
    PMID: 32127904 DOI: 10.4314/ahs.v19i4.50
    Background: Carcinoma ex pleomorphic adenoma (CA-ex-PA) is extremely unusual in minor salivary glands of oral cavity. CAex-PA is a carcinomatous change as a primary or as a recurrence of pleomorphic adenoma.

    Objective: Due to resemblance of clinical symptoms of Ca ex PA and benign pleomorphic adenoma, it is mandatory for surgeons to keep high degree of clinical alertness, considering the peculiarity of this tumor.

    Case Report: 54-year-old male presented with swelling on left side in the pre-auricular region from the middle of zygomatic arch to mastoid process and from tragus of the ear up to angle of mandible. Fine needle aspiration cytology revealed a mixture of benign and malignant components. Total left parotidectomy with left radical neck dissection followed by reconstruction with cervicodeltopectoral flap was performed. Combination of chemotherapy and radiotherapy were given to patient. Histologic examination and pre-operative fine needle aspiration cytology confirmed the diagnosis of Carcinoma ex pleomorphic adenoma (CA-ex-PA). Two-year follow-up of patient showed no recurrence of the lesion.

    Conclusion: Due to the similarity in the clinical symptoms of CA-ex-PA and benign pleomorphic adenoma, it is vital that clinicians maintain a high degree of clinical vigilance, considering the oddity of this malignancy.

  15. Joshi C, Bapat R, Anderson W, Dawson D, Hijazi K, Cherukara G
    Trends Cardiovasc Med, 2021 01;31(1):69-82.
    PMID: 31983534 DOI: 10.1016/j.tcm.2019.12.005
    BACKGROUND: Microbial translocation from inflamed periodontal pockets into coronary atheroma via systemic circulation is one of the proposed pathways that links periodontitis and myocardial infarction (MI). The purpose of this systematic review is to determine the reported prevalence of periodontal microorganisms in coronary atheroma and/or aspirated clot samples collected from MI patients with periodontal disease.

    METHODOLOGY: The "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA) guidelines were followed. Six databases were systematically searched using Medical Subject Headings/Index and Entree terms. After a thorough screening, fourteen publications spanning over ten years (2007-2017) were eligible for this systematic review and meta-analysis.

    RESULTS: Out of 14 included studies, 12 reported presence of periodontal bacterial DNA in coronary atherosclerotic plaque specimens. Overall, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were the most frequently detected periodontal bacterial species. Meta-analysis revealed that the prevalence of P. gingivalis was significantly higher than A. actinomycetemcomitans in coronary atheromatous plaque samples. Apart from periodontal microbes, DNA from a variety of other microbes e.g. Pseudomonas fluorescens, Streptococcus species, Chlamydia pneumoniae were also recovered from the collected samples.

    CONCLUSION: Consistent detection of periodontal bacterial DNA in coronary atheroma suggests their systemic dissemination from periodontal sites. It should further be investigated whether they are merely bystanders or induce any structural changes within coronary arterial walls.

  16. Joshi C, Bapat R, Anderson W, Dawson D, Cherukara G, Hijazi K
    J Clin Periodontol, 2021 Dec;48(12):1570-1586.
    PMID: 34545592 DOI: 10.1111/jcpe.13550
    AIM: The present systematic review and meta-analysis assessed the strength of a reported association between elevated serum anti-periodontal bacterial antibody responses and coronary heart disease (CHD).

    MATERIALS AND METHODS: Twenty original studies were identified after systematically searching five databases. The majority (n = 11) compared serum anti-Porphyromonas gingivalis (Pg) and/or anti-Aggregatibacter actinomycetemcomitans (Aa) IgG antibody responses between CHD patients and control participants. The strength of the association between serum anti-Pg antibodies and CHD (n = 10) and serum anti-Aa antibodies and CHD (n = 6) was investigated using a meta-analysis approach separately.

    RESULTS: Most studies (61%) reported that the serum IgG antibody responses were elevated in CHD patients than in controls. The meta-analyses showed a significant association between elevated serum IgG antibody responses (anti-Pg and anti-Aa) and CHD, with pooled odds ratios of 1.23 [95% confidence interval (CI): 1.09-1.38, p = .001] and 1.25 (95% CI: 1.04-1.47, p = .0004), respectively.

    CONCLUSIONS: A modest increase of CHD events in individuals with higher serum anti-Pg and anti-Aa IgG antibody responses may support their use as potential biomarkers to detect and monitor at-risk populations. However, the observed inconsistencies with the design and interpretation of immunoassays warrant standardization of the immunoassays assessing antibody responses against periodontal bacteria.

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