Considering the limitation of fossil fuel resources and their environmental effects, the use of renewable energies is increasing. In the current research, a combined cooling and power production (CCPP) system is investigated, the energy source of which is solar energy. Solar energy absorbs by solar flat plate collectors (SFPC). The system produces power with the help of an organic Rankine cycle (ORC). An ejector refrigeration cycle (ERC) system is considered to provide cooling capacity. The motive flow is supplied from the expander extraction in the ERC system. Various working fluids have been applied so far for the ORC-ERC cogeneration system. This research investigates the effect of using two working fluids R-11 and R-2545fa, and the zeotropic mixtures obtained by mixing these two fluids. A multiobjective optimization process is considered to select the appropriate working fluid. In the optimization design process, the goal is to minimize the total cost rate (TCR) and maximize the exergy efficiency of the system. The design variables are the quantity of SFPC, heat recovery vapor generator (HRVG) pressure, ejector motive flow pressure, evaporator pressure, condenser pressure, and entertainment ratio. Finally, it is observed that using zeotropic mixtures obtained from these two refrigerants has a better result than using pure refrigerants. Finally, it is observed that the best performance is achieved when R-11 and R245fa are mixed with a ratio of 80 to 20%, respectively and led to 8.5% improvement in exergy efficiency, while the increase in TCR is only 1.5%.
Clinacanthus nutans, an herbal shrub belonging to the Acanthaceae family, is traditionally used as a functional food to treat various ailments in Malaysia and Indonesia. Although the polar fraction of this plant shows non-toxic effect, the toxicity of the non-polar extract is not reported so far. The present study aimed to assess the toxic effect and determine the lethal concentration of this non-polar fraction using zebrafish embryos. The n-hexane fraction was partitioned from the crude extract of C. nutans obtained using 80% methanolic solution. After spawning of the adult male and female zebrafish, the eggs were collected, transferred into a 96-well plate and incubated with the n-hexane fraction at concentrations of 15.63 μg/ml, 31.25 μg/ml, 62.5 μg/ml, 125 μg/ml, 250 μg/ml and 500 μg/ml in 2% DMSO. The survival and sublethal endpoint were assessed, the mortality and hatchability rates were calculated based on microscopic observation, while the heartbeat rate was measured using DanioScope software. The median lethal concentration (LC50) of the C. nutans n-hexane fraction, which was determined using probit analysis, was calculated to be 75.49 μg/mL, which is harmful. Moreover, gas chromatography-mass spectrometry (GC-MS) analysis revealed the presence of palmitic acid, phytol, hexadecanoic acid, 1-monopalmitin, stigmast-5-ene, pentadecanoic acid, heptadecanoic acid, 1-linolenoylglycerol and stigmasterol in the n-hexane fraction.