Displaying publications 1 - 20 of 49 in total

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  1. Noraini T, Ruzi A, Nadiah N, Nisa R, Maideen H, Solihani S
    Sains Malaysiana, 2012;41:53-62.
    Kajian anatomi stip telah dijalankan ke atas tujuh spesies Davallia, iaitu D. denticulata, D. divaricata, D. trichomanioides var. trichomanioides, D. trichomanioides var. lorrainii, D. corniculata, D. repens dan D. solida var. solida di Malaysia. Kajian ini melibatkan keratan rentas bahagian stip menggunakan mikrotom gelongsor. Hasil kajian menunjukkan ciri anatomi stip seperti bentuk luaran stip, corak kehadiran sel sklerenkima di bawah epidermis, jenis dan bentuk stel, bilangan berkas vaskular, bilangan lapisan sel parenkima dan juga kehadiran cuping pada keratan rentas stip boleh digunakan untuk pengecaman dan pembezaan spesies. Ciri sepunya bagi genus Davallia ialah kehadiran sel sklerenkima mengelilingi stel dan di bawah lapisan sel epidermis, serta kehadiran sel parenkima berdinding tebal. Banyak ciri diagnostik ditemui dalam kajian ini dan antaranya ialah kehadiran satu cuping pada keratan stip tengah ditemui hanya pada D. trichomanioides var. lorrainii, corak 4 kehadiran sel sklerenkima di bawah epidermis ditemui hanya pada D. repens, corak 3 hanya ditemui pada D. solida var. solida, corak 5 dan 7 hanya ditemui pada D. corniculata, stel jenis dorsiventral protostel bagi D. divaricata dan bagi D. trichomanioides var. trichomanioides pula, kehadiran stel bentuk arka pada stip atas, stip tengah dan juga bawah merupakan ciri diagnostik yang baik untuk pengecaman spesies ini. Hasil kajian ini menunjukkan bahawa ciri anatomi stip mempunyai nilai taksonomi dalam genus Davallia dan boleh digunakan sebagai data sokongan untuk tujuan pengecaman dan pembezaan spesies.
    Matched MeSH terms: Epidermis
  2. Maideen H, Nik Norhazrina N, Nur-aliah M, Noraini T, Nur Farhanim I, Syazwani B
    Sains Malaysiana, 2018;47:645-649.
    Kajian anatomi rizom dan stip telah dijalankan ke atas empat spesies Pleocnemia yang terdapat di Semenanjung Malaysia
    iaitu P. irregularis, P. conjugata, P. hemiteliiformis dan P. olivacea untuk mengkaji variasi ciri yang terdapat pada rizom
    dan stip ini. Kajian ini melibatkan keratan rentas stip dan rizom dengan menggunakan mikrotom gelongsor. Ciri anatomi
    stip seperti bentuk luaran, corak kehadiran sel sklerenkima di bawah epidermis, jenis dan bentuk stel dan ciri anatomi
    rizom seperti kehadiran sel rembes tanin dan kehadiran serta jenis trikom pada sesetengah spesies boleh digunakan untuk
    pengecaman spesies. Ciri sepunya bagi spesies Pleocnemia yang dikaji ialah kehadiran sel sklerenkima mengelilingi stel
    dan di bawah lapisan sel epidermis, stel jenis kompleks serta stel bagi kesemua spesies kajian berbentuk protostel primitif
    (bulat). Antara ciri diagnosis yang ditemui dalam kajian ini ialah bentuk luaran stip, bilangan lapisan skelerenkima
    di bawah epidermis, kehadiran sel rembes tanin bagi spesies P. irregularis dan P. hemiteliiformis serta kehadiran jenis
    trikom yang berbeza dalam keempat-empat spesies. Ciri diagnosis ini adalah ciri yang baik untuk pengecaman spesies
    kajian. Keputusan kajian ini menunjukkan bahawa ciri anatomi stip dan rizom mempunyai nilai taksonomi dalam genus
    Pleocnemia dan boleh digunakan sebagai data sokongan untuk pengecaman dan pembezaan spesies.
    Matched MeSH terms: Epidermis
  3. Goh CF, Hadgraft J, Lane ME
    Int J Pharm, 2022 Feb 25;614:121447.
    PMID: 34998922 DOI: 10.1016/j.ijpharm.2021.121447
    For effective topical and transdermal drug delivery, it is necessary for most actives to penetrate and permeate through the stratum corneum (SC). Extensive investigation of the thermal behaviour of mammalian SC has been performed to understand the barrier function of the skin. However, little attention has been paid to the related experimental variables in thermal analysis of the SC using differential scanning calorimetry that may influence the results obtained from such studies. In this review, we provide a comprehensive overview of the thermal transitions of the SC of both porcine and human skin. More importantly, the selection and impact of the experimental and instrumental parameters used in thermal analysis of the SC are critically evaluated. New opportunities for the use of thermal analysis of mammalian SC in advancing skin research, particularly for elucidation of the actions of excipients employed in topical and transdermal formulations on the skin are also highlighted.
    Matched MeSH terms: Epidermis*
  4. Amirul-Aiman Ahmad Juhari, Noraini Talip, Siti Khaulah Abdul Razak, Nurul-Syahirah Mansur, Amalia Rusydi, Ruzi Abdul Rahman, et al.
    Trop Life Sci Res, 2019;30(2):1-20.
    MyJurnal
    Acanthaceae merupakan famili tumbuhan berbunga di bawah order Lamiales dan terdiri daripada sekurang-kurangnya 4,000 spesies di kawasan tropika dan juga kawasan subtropika dengan genus Justicia merupakan genus terbesar. Kajian mikromorfologi petal dan sepal telah dijalankan ke atas ke atas enam spesies iaitu Justicia betonica L., J. carnea Lindl., J. comata (L.) Lam., J. gendarussa Burm.f., J. procumbens L. dan J. ptychostoma Nees. Kaedah kajian termasuklah penetapan bunga di dalam larutan penetap, siri dehidrasi, titik pengeringan genting dan cerapan di bawah mikroskop imbasan elektron. Hasil kajian menunjukkan kesemua enam spesies mempunyai variasi dan perbezaan mikromorfologi pada permukaan epidermis petal dan sepal. Kutikel lilin boleh ditemui pada kedua-dua permukaan epidermis petal dan sepal kesemua spesies yang dikaji. Kutikel lilin butir merupakan satu-satunya jenis kutikel lilin yang ditemui pada kesemua permukaan petal dan sepal spesies kajian. Terdapat lapan jenis trikom ditemui pada permukaan epidermis sepal dan juga lapan jenis trikom pada permukaan epidermis petal. Justicia betonica boleh dibezakan secara langsung dengan kehadiran stomata amfidiasitik pada permukaan epidermis petal dan stomata tidak hadir pada permukaan petal spesies yang lain. Kesimpulannya, hasil kajian ini membuktikan ciri mikromorfologi petal dan sepal mempunyai kesignifikan sistematik dan boleh digunakan sebagai data sokongan bagi pembezaan dan pengenalpastian spesies dalam genus Justicia.
    Matched MeSH terms: Epidermis
  5. Solihani S, Noraini T, Ruzi A, Chung R
    Kajian anatomi perbandingan daun dilakukan ke atas tiga spesies daripada genus Coelostegia (C. griffithii, C. borneensis dan C. chartacea) dan juga Ceiba pentandra Gaertn. (Bombacaceae) sebagai spesies perbandingan dalam famili yang sama. Kajian yang dilakukan melibatkan keratan rentas lamina dan tepi daun menggunakan mikrotom gelongsor. Penjernihan daun dilakukan menggunakan larutan 1% Basic Fuchsin di dalam 10% KOH. Hasil kajian menunjukkan ciri sepunya semua spesies Coelostegia yang dikaji iaitu kehadiran sel lendir, jenis trikom, jenis dan taburan hablur, kehadiran sel sklerenkima dan jenis peruratan tengah lamina. Ciri unik yang dikongsi oleh semua spesies genus Coelostegia ialah kehadiran satu hablur tunggal di atas berkas vaskular lamina yang menyambungkannya ke bahagian adaksial epidermis dan seakan-akan membentuk tiang serabut. Manakala variasi interspesies dalam Coelostegia yang boleh digunakan untuk membezakan spesies dalam genus ini ialah bentuk luaran tepi daun, peruratan tepi daun dan taburan trikom. Dalam kajian ini, terdapat tujuh ciri yang boleh membezakan antara Coelostegia dan Ceiba pentandra. Ciri tersebut adalah kehadiran trakeid membengkak yang dapat dilihat pada peruratan lamina, corak berkas vaskular pada tulang daun dan petiol, kehadiran dan jenis hablur, kehadiran dan jenis trikom, sel lendir, sklerenkima pada lamina, hipodermis, sklerenkima pada berkas vaskular petiol dan kehadiran kolenkima. Kajian ini membuktikan bahawa gabungan beberapa ciri anatomi daun mempunyai nilai taksonomi yang boleh digunakan untuk membezakan spesies.
    Matched MeSH terms: Epidermis
  6. Noorma Wati Haron, Nordiyanah Anuar, Rubashiny Veeramohan
    Sains Malaysiana, 2015;44:643-650.
    A comparative leaf micromorphological study of Melastoma malabathricum, M. malabathricum var. alba and M.
    sanguineum (Melastomataceae) was carried out by scanning electron microscope. Characters such as epidermal cell
    shape, trichomes and stomatal type and distribution were observed. Non-glandular trichomes are present in all species
    examined. The stomata are all of paracytic type and dispersed randomly over the whole abaxial surface. The patterns of
    surface sculpturing and outer stomatal rim are unique in all the species examined. Leaf micromorphology has significant
    taxonomic value in the genus Melastoma and the present study has added some new taxonomic information for the genus
    Melastoma.
    Matched MeSH terms: Plant Epidermis
  7. Amirul-aiman A, Noraini T, Nurul-aini C
    Sains Malaysiana, 2017;46:1679-1685.
    Acanthaceae merupakan famili tumbuhan angiosperma di bawah order Lamiales yang terdiri daripada sekurang-kurangnya 4000 spesies sama ada spesies tropika atau subtropika. Spesies daripada famili ini ditemui di pelbagai habitat dan mempunyai pelbagai morfologi serta corak taburan geografi. Walau bagaimanapun, maklumat mengenai ciri anatomi bagi Acanthaceae masih dangkal sehingga ke hari ini. Objektif kajian ini ialah untuk mengenal pasti jenis trikom yang hadir pada permukaan epidermis adaksial dan abaksial sepal dan juga petal bunga bagi beberapa spesies terpilih daripada Acanthaceae di Semenanjung Malaysia. Kajian ini melibatkan pengumpulan sampel di lapangan, penyediaan spesimen baucer, teknik kajian epidermis petal, cerapan di bawah mikroskop cahaya dan juga cerapan di bawah mikroskop imbasan elektron. Tiga puluh jenis trikom dicerap dalam kajian ini dan daripada jumlah tersebut, 23 jenis trikom dicerap hadir pada permukaan epidermis petal manakala 17 jenis trikom dicerap hadir pada permukaan epidermis sepal. Jenis trikom yang direkodkan ialah trikom ringkas unisel dan ringkas multisel, trikom kelenjar kapitat dan kelenjar peltat serta juga trikom berlengan. Keputusan kajian ini menunjukkan kehadiran dan jenis trikom pada permukaan sepal dan petal mempunyai nilai taksonomi yang berguna untuk tujuan pembezaan dan pengecaman spesies. Maklumat ciri morfologi trikom yang diperoleh daripada kajian ini merupakan maklumat baharu ciri anatomi bunga bagi Acanthaceae.
    Matched MeSH terms: Epidermis
  8. Baleg SM, Bidin N, Suan LP, Ahmad MF, Krishnan G, Johari AR, et al.
    J Cosmet Dermatol, 2015 Sep;14(3):246-53.
    PMID: 25817596 DOI: 10.1111/jocd.12142
    The aim of this study was to evaluate the effects of multiple pulses on the depth of injury caused by CO2 laser in an in vivo rat model.
    Matched MeSH terms: Epidermis/radiation effects
  9. Goh CF, Moffat JG, Craig DQM, Hadgraft J, Lane ME
    Mol Pharm, 2019 01 07;16(1):359-370.
    PMID: 30525649 DOI: 10.1021/acs.molpharmaceut.8b01027
    Drug crystallization on and in the skin has been reported following application of topical or transdermal formulations. This study explored novel probe-based approaches including localized nanothermal analysis (nano-TA) and photothermal microspectroscopy (PTMS) to investigate and locate drug crystals in the stratum corneum (SC) of porcine skin following application of simple ibuprofen (IBU) formulations. We also conducted in vitro skin permeation studies and tape stripping. The detection of drug crystals in the SC on tape strips was confirmed using localized nano-TA, based on the melting temperature of IBU. The melting of IBU was also evident as indicated by a double transition and confirmed the presence of drug crystals in the SC. The single point scans of PTMS on the tape strips allowed collection of the photothermal FTIR spectra of IBU, confirming the existence of drug crystals in the skin. The combined methods also indicated that drug crystallized in the SC at a depth of ∼4-7 μm. Future studies will examine the potential of these techniques to probe crystallization of other commonly used actives in topical and transdermal formulations.
    Matched MeSH terms: Epidermis/metabolism*
  10. Hanifi N, Halim AS, Aleas CF, Singh J, Marzuki M, Win TT, et al.
    Exp Clin Transplant, 2015 Jun;13(3):273-8.
    PMID: 26086837
    Skin grafting has been evolving as an important application in reconstructive surgery. Mixed reports about the survival of allogeneic and xenogeneic keratinocytes require further substantiation to determine the role of these cells in wound healing.
    Matched MeSH terms: Epidermis/pathology; Epidermis/physiopathology; Epidermis/transplantation*
  11. Nurhanim M, Noraini T, Chung R, Nurul-Aini, Ruzi A
    Sains Malaysiana, 2014;43:331-338.
    Kajian anatomi dan mikromorfologi daun telah dijalankan ke atas lima takson dalam genus Schoutenia Korth. (Malvaceae subfam. Brownlowioideae). Lima takson yang dipilih dalam kajian ini ialah S. kunstleri, S. leprosula, S. accrescens subsp. accrescens, S. accrescens subsp. borneensis dan S. accrescens subsp. stellata. Kajian anatomi melibatkan kaedah hirisan dengan mikrotom gelongsor pada bahagian petiol, lamina, tulang daun dan tepi daun, kaedah penjernihan lamina dan kaedah siatan epidermis daun, penjernihan dengan larutan peluntur, pewarnaan dengan Safranin dan Alcian Blue, pelekapan Canada Balsam dan cerapan bawah mikroskop cahaya. Kajian mikromorfologi melibatkan kaedah pendehidratan, titik pengeringan kritikal, saduran emas dan cerapan bawah mikroskop imbasan elektron. Objektif kajian ialah untuk melihat nilai taksonomi ciri anatomi dan mikromorfologi daun dalam genus yang dikaji. Hasil kajian menunjukkan terdapat sembilan ciri sepunya, tujuh ciri variasi yang boleh digunakan untuk pembezaan spesies dan dua ciri diagnostik yang boleh digunakan untuk pengecaman spesies. Ciri tersebut ialah corak hiasan kutikel pada S. kunstleri dan juga kehadiran sel kolenkima lamela pada S. accrescens subsp. stellata. Hasil kajian menunjukkan ciri anatomi serta mikromorfologi daun dalam genus Schoutenia mempunyai nilai taksonomi terutama dalam pembezaan dan pengecaman pada peringkat spesies dan subspesies.
    Matched MeSH terms: Epidermis
  12. Strout G, Russell SD, Pulsifer DP, Erten S, Lakhtakia A, Lee DW
    Ann Bot, 2013 Oct;112(6):1141-8.
    PMID: 23960046 DOI: 10.1093/aob/mct172
    BACKGROUND AND AIMS: Blue-green iridescence in the tropical rainforest understorey sedge Mapania caudata creates structural coloration in its leaves through a novel photonic mechanism. Known structures in plants producing iridescent blues consist of altered cellulose layering within cell walls and in special bodies, and thylakoid membranes in specialized plastids. This study was undertaken in order to determine the origin of leaf iridescence in this plant with particular attention to nano-scale components contributing to this coloration.

    METHODS: Adaxial walls of leaf epidermal cells were characterized using high-pressure-frozen freeze-substituted specimens, which retain their native dimensions during observations using transmission and scanning microscopy, accompanied by energy-dispersive X-ray spectroscopy to identify the role of biogenic silica in wall-based iridescence. Biogenic silica was experimentally removed using aqueous Na2CO3 and optical properties were compared using spectral reflectance.

    KEY RESULTS AND CONCLUSIONS: Blue iridescence is produced in the adaxial epidermal cell wall, which contains helicoid lamellae. The blue iridescence from cell surfaces is left-circularly polarized. The position of the silica granules is entrained by the helicoid microfibrillar layers, and granules accumulate at a uniform position within the helicoids, contributing to the structure that produces the blue iridescence, as part of the unit cell responsible for 2 ° Bragg scatter. Removal of silica from the walls eliminated the blue colour. Addition of silica nanoparticles on existing cellulosic lamellae is a novel mechanism for adding structural colour in organisms.

    Matched MeSH terms: Plant Epidermis/metabolism; Plant Epidermis/ultrastructure; Plant Epidermis/chemistry
  13. Nugroho H, Ahmad Fadzil MH, Shamsudin N, Hussein SH
    Skin Res Technol, 2013 Feb;19(1):e72-7.
    PMID: 22233154 DOI: 10.1111/j.1600-0846.2011.00610.x
    Vitiligo is a cutaneous pigmentary disorder characterized by depigmented macules and patches that result from loss of epidermal melanocytes. Physician evaluates the efficacy of treatment by comparing the extent of vitiligo lesions before and after treatment based on the overall visual impression of the treatment response. This method is called the physician's global assessment (PGA) which is subjective. In this article, we present an innovative digital image processing method to determine vitiligo lesion area in an objective manner.
    Matched MeSH terms: Epidermis/metabolism; Epidermis/pathology*
  14. Saleem MZ, Akhtar R, Aslam A, Rashid MI
    Trop Biomed, 2019 Dec 01;36(4):1081-1086.
    PMID: 33597477
    Ticks are important ectoparasites which transmit many disease pathogen to animals; these are labelled tick borne diseases (TBD). Tick induced damage to skin and hides has not received attention. Skin and hides are important for the leather product industry, particularly in Pakistan. Due to economic importance and financial loss by ticks in leather industry, the present study was designed to investigate skin and hides damage due to ticks at microscopic level. Naturally tick infested tissue samples of hides and skin were collected from slaughter houses. Primary lesions at tick feeding sites showed epidermal edema with adjacent dermal edema. Histopathological examination revealed degeneration of epidermal layer down to the basal layer. Epidermal and sub dermal layers often displayed focal necrosis infiltrated with neutrophils and mononuclear cells at tick bite sites. Hyperplasia of keratinocytes was also seen at sites of ruptured epidermis. Quality of leather depends upon the grain (Outer) surface skin/hides. Ticks infestation damages the outer surface, due to bites, inflammatory responses, and secondary bacterial infections that often become established at feeding sites. Control of ticks should be given consideration to reduce infestation induced losses in the leather industry in Pakistan.
    Matched MeSH terms: Epidermis/parasitology; Epidermis/pathology
  15. Chong K, Joshi S, Jin LT, Shu-Chien AC
    Proteomics, 2006 Apr;6(7):2251-8.
    PMID: 16385477
    The discus fish (Symphysodon aequifasciata) is a cichlid demonstrating advanced mode of parental care towards fry. Both male and female fish utilized epidermal mucus secreted from specialized epidermal cells to feed developing fry. We utilized proteomics to compare protein profile from parental and nonparental fish. Gel analysis revealed a total of 35 spots that were up-regulated in parental mucus. In tandem, another 18 spots were uniquely expressed in parental mucus. MS analysis of these spots identified proteins such as fructose biphosphate aldolase, nucleoside diphosphate kinase, and heat shock proteins, which are essential to support energy provision, cell repair and proliferation, stress mediation, and defense mechanism in parental fish during parental-care period. Concurrently, the detection of several antioxidant-related proteins such as thioredoxin peroxidase and hemopexin suggests a need to overcome oxidative stress during hypermucosal production in parental-care behavior. A C-type lectin was also found to be uniquely expressed in parental mucus and could have important role in providing antimicrobial defense to both parental fish and fry. In summary, our study shows that discus mucus proteome undergoes changes in protein expression during parental-care period.
    Matched MeSH terms: Epidermis/metabolism*; Epidermis/secretion*
  16. Lau P, Bidin N, Krishnan G, AnaybBaleg SM, Sum MB, Bakhtiar H, et al.
    PMID: 26313856 DOI: 10.1016/j.jphotobiol.2015.08.009
    The photobiostimulation effects of near infrared 808 nm diode laser irradiance on diabetic wound were investigated. 120 rats were induced with diabetes by streptozotocin injection. Full thickness punch wounds of 6mm diameter were created on the dorsal part of the rats. All rats were randomly distributed into four groups; one group served as control group, whereas three groups were stimulated daily with unchanged energy density dose of 5 J/cm(2) with different power density, which were 0.1 W/cm(2), 0.2 W/cm(2) and 0.3 W/cm(2) with different exposure duration of 50s, 25s and 17s, respectively. Ten rats from each group were sacrificed on day 3, 6 and 9, respectively. Skin tissues were removed for histological purpose. The contraction of wound was found optimized after exposure with 0.1 W/cm(2). Based on the histological evidence, laser therapy has shown able to promote wound repair through enhanced epithelialization and collagen fiber synthesis. Generally, irradiated groups were advanced in terms of healing than non-irradiated group.
    Matched MeSH terms: Epidermis/pathology; Epidermis/radiation effects
  17. Phyu WK, Ong KC, Kong CK, Alizan AK, Ramanujam TM, Wong KT
    Sci Rep, 2017 03 21;7:45069.
    PMID: 28322333 DOI: 10.1038/srep45069
    Hand-foot-and-mouth disease is a self-limiting paediatric infectious disease commonly caused by Enterovirus A71 (Genus: Enterovirus, Family: Picornaviridae). Typical lesions in and around the hands, feet, oral cavity and other places may rarely be complicated by acute flaccid paralysis and acute encephalomyelitis. Although virus is readily cultured from skin vesicles and oral secretions, the cellular target/s of Enterovirus A71 in human skin and oral mucosa are unknown. In Enterovirus A71-infected human skin and oral mucosa organotypic cultures derived from the prepuce and lip biopsies, focal viral antigens and viral RNA were localized to cytoplasm of epidermal and mucosal squamous cells as early as 2 days post-infection. Viral antigens/RNA were associated with cytoplasmic vacuolation and cellular necrosis. Infected primary prepuce epidermal keratinocyte cultures showed cytopathic effects with concomitant detection of viral antigens from 2 days post-infection. Supernatant and/or tissue homogenates from prepuce skin organotypic cultures and primary prepuce keratinocyte cultures showed viral titres consistent with active viral replication. Our data strongly support Enterovirus A71 squamous epitheliotropism in the human epidermis and oral mucosa, and suggest that these organs are important primary and/or secondary viral replication sites that contribute significantly to oral and cutaneous viral shedding resulting in person-to-person transmission, and viraemia, which could lead to neuroinvasion.
    Matched MeSH terms: Epidermis/pathology; Epidermis/virology*
  18. Uddin S, Chowdhury MR, Wakabayashi R, Kamiya N, Moniruzzaman M, Goto M
    Chem Commun (Camb), 2020 Oct 19.
    PMID: 33073787 DOI: 10.1039/d0cc04491a
    We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1,2-dimyristoyl-sn-glycero-3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. These materials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.
    Matched MeSH terms: Epidermis
  19. Muslim A, Hyakumachi M, Kageyama K, Suwandi S
    Trop Life Sci Res, 2019 Jan;30(1):109-122.
    PMID: 30847036 DOI: 10.21315/tlsr2019.30.1.7
    Treatment with hypovirulent binucleate Rhizoctonia (HBNR) isolates induced systemic resistance against anthracnose infected by Colletotrichum orbiculare in cucumber, as there were no direct interaction between HBNR and C. orbiculare. This is because of the different distances between HBNR and C. orbiculare, where the root was treated with HBNR isolate and C. orbiculare was challenged and inoculated in leaves or first true leaves were treated with HBNR isolate and C. orbiculare was challenged and inoculated in second true leaves. The use of barley grain inocula and culture filtrates of HBNR significantly reduced the lesion diameter compared to the control (p = 0.05). The total lesion diameter reduction by applying barley grain inoculum of HBNR L2, W1, W7, and Rhv7 was 28%, 44%, 39%, and 40%, respectively. Similar results was also observed in treatment using culture filtrate, and the reduction of total lesion diameter by culture filtrate of HBNR L2, W1, W7, and Rhv7 was 45%, 46%, 42%, and 48%, respectively. When cucumber root was treated with culture filtrates of HBNR, the lignin was enhanced at the pathogen penetration, which is spread along the epidermis tissue of cucumber hypocotyls. Peroxidase activity in hypocotyls in the treated cucumber plant with culture filtrates of HBNR significantly increased before and after inoculation of pathogens as compared to the control. Significant enhancement was also observed in the fast-moving anodic peroxidase isozymes in the treated plants with culture filtrates of HBNR. The results showed the elicitor(s) contained in culture filtrates in HBNR. The lignin deposition as well as the peroxidase activity is an important step to prevent systemically immunised plants from pathogen infection.
    Matched MeSH terms: Epidermis
  20. Ooi PS, Draman N, Yusoff SSM, Zain WZW, Ganasagaran D, Chua HH
    Korean J Fam Med, 2019 Jul;40(4):269-272.
    PMID: 30486607 DOI: 10.4082/kjfm.17.0143
    Mammary Paget's disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget's disease is relatively unknown; nonetheless, there are two popular theories that support the underlying carcinoma and de novo carcinogenesis. For the attending medical practitioner, mammary Paget's disease poses a diagnostic and therapeutic dilemma, especially in the absence of a clinically palpable breast mass. We report a rare case of a 48-year-old Malay woman who presented at Hospital Universiti Sains Malaysia, Kelantan, Malaysia with the symptom of skin erosion on the left nipple and unresponsiveness to multiple topical treatments. A full evaluation and assessment of the patient were conducted, and mammary Paget's disease was diagnosed.
    Matched MeSH terms: Epidermis
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