Displaying publications 1 - 20 of 378 in total

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  1. Loong SC
    Family Physician, 1989;1:19-21.
    Matched MeSH terms: Peripheral Nervous System Diseases
  2. Highet HC
    Matched MeSH terms: Peripheral Nervous System Diseases
  3. Pillay AC
    JUMMEC, 1998;3:22-46.
    Senescent-decliue in the nervous-system functions is very frequently atbibuted to age-related neurone-loss. Processes and mechanisms involved in neuro- degeneration form part of the structural frame-work for interpreting the functional consequences. The literature concerning this matter are confusing and contradicting. The behaviour of cranial nerve ganglia was studied using neuro-histological techniques. On the evidence available in the present study, the dark cells are considered as active ones; the light cells are considered as those which have failed to establish functional projections, inactive, dying, dead or degenerating ones. Probably it is during the me- dium-sized stage of cell growth, the peripheral and central processes (of axons) begin to grow from the cell body and attempt to get established in their projection fields. The light cells have appeared among the very-small cells just on the day of hatching. This probably signifies the possible attempt to elinlinate the growing cells since they are no longer needed to replace larger categories of cells which have already well- developed neuronat connections at this stage. It is assumed that the time of appear- ance of light cells might be indirectly related to the onset of establishment of active functional connections of neurones and to the functional importance of the organs which it supplies. KEYWORDS: Neurone-Loss and Ageing, Dark and Light Neurones, Sensory and Autonomic Ganglia
    Matched MeSH terms: Autonomic Nervous System; Nervous System
  4. Mohd Syukran Abdul Khadir
    MyJurnal
    Otot memainkan
    peranan penting dalam setiap pergerakan utama manusia seperti berjalan, bernafas,
    mengangkat barang dan sebagainya. Harris dan Watkins (1993) mentakrifkan kekuatan otot
    sebagai keupayaan otot rangka untuk membangunkan daya untuk tujuan memberikan
    kestabilan dan mobiliti di dalam sistem otot, fungsi pergerakan boleh berlaku. Kekuatan otot
    berbeza mengikut umur dan jantina. Terdapat pelbagai kajian yang dilakukan untuk mengukur
    kekuatan otot bagi golongan dewasa. Namun demikian, masih kurang penyelidikan telah
    dijalankan ke atas kekuatan otot bagi kanak-kanak yang bersekolah di peringkat taska atau pra
    sekolah. Kanak-kanak yang belajar di peringkat taska atau pra sekolah adalah kanak-kanak
    yang berumur dari 4 hingga 6 tahun. Kajian ulasan ringkas ini mengupas beberapa faktor
    yang mempengaruhi kekuatan otot dalam kalangan kanak-kanak pra sekolah. Kajian-kajian
    yang dipilih telah menepati kriteria-kriteria yang telah di tetapkan iaitu: a) hasil dapatan
    menunjukkan kaitan antara kekuatan otot dan pelajar pra sekolah dan b) faktor mempengaruhi
    kekuatan otot di kalangan kanak-kanak.
    Matched MeSH terms: Autonomic Nervous System Diseases
  5. Goh T, Ghani Rafek A, Hariri Arifin M
    Sains Malaysiana, 2014;43:751-756.
    Kekasaran permukaan satah ketakselanjaran adalah parameter penting untuk penilaian kestabilan struktur pengorekan dalam jasad batuan kerana ia mempengaruhi tingkah-laku ricihan dan nilai sudut geseran puncak satah tersebut. Beberapa kaedah boleh digunakan untuk menentukan kekasaran permukaan ketakselanjaran. Kertas ini memperkenalkan satu pendekatan yang mudah dalam bentuk tiga (3) persamaan polinominal untuk mengkorelasikan sudut geseran puncak ketakselanjaran (fp) batuan granit segar, terluluhawa sedikit dan terluluhawa sederhana dengan pekali kekasaran kekar, (JRC). Persamaan polinominal ketakselanjaran batuan granit segar ialah fp1 = -0.071JRC2 + 3.56JRC + 35.6. Persamaan polinominal ketakselanjaran batuan granit terluluhawa sedikit dan terluluhawa sederhana masing-masing ialah fp2 = -0.087JRC2 + 4.32JRC + 34.1 dan fp3 = -0.133JRC2 + 5.08JRC + 29. Hasil kajian ini memberikan satu kaedah alternatif penganggaran nilai fp satah ketakselanjaran daripada penentuan nilai PKK pada permukaan ketakselanjaran batuan granit di lapangan.
    Matched MeSH terms: Autonomic Nervous System Diseases
  6. Mohd Raihan Taha, Mohammad Khajehzadeh, Ahmed El-Shafie
    Sains Malaysiana, 2012;41:847-854.
    Objektif kajian ini adalah untuk menunjukkan pembangunan kaedah berangka untuk menilai keboleharapan cerun tanah dan menentukan kebarangkalian permukaan gelonsoran genting. Fungsi prestasi dirumuskan menggunakan kaedah had keseimbangan Bishop mudah untuk mengira indeks keboleharapan. Indeks keboleharapan yang ditakrifkan oleh Hasofer dan Lind digunakan sebagai indeks ukuran keselamatan. Pencarian permukaan gelonsoran genting secara kebarangkaliannya yang berkaitan dengan indeks keboleharapan terendah dirumuskan sebagai masalah pengoptimuman.
    Seterusnya pengoptimuman kelompok zarah digunakan untuk mengira indeks keboleharapan Hasofer dan Lind dan kebarangkalian permukaan kegagalan genting. Penggunaan algorithma ini ditunjukkan melalui tiga contoh berangka daripada kajian terdahulu. Keputusan menunjukkan bahawa kaedah yang dicadangkan berupaya untuk memberikan penyelesaian yang lebih baik bagi analisis keboleharapan cerun tanah berbanding dengan kaedah yang dilaporkan dalam kajian-kajian terdahulu.
    Matched MeSH terms: Autonomic Nervous System Diseases
  7. Mahadev V
    Med J Malaya, 1970 Jun;24(4):290-6.
    PMID: 4248350
    Matched MeSH terms: Nervous System Diseases/diagnosis*
  8. Heyneman D
    Med J Malaya, 1966 Sep;21(1):84-9.
    PMID: 4224884
    Matched MeSH terms: Central Nervous System Diseases/etiology*
  9. Viswanathan S, Hung SKY, Goyal V, Apiwattanakul M, Thirugnanam UN, Abdullah S, et al.
    J Clin Apher, 2018 Oct;33(5):559-568.
    PMID: 29626354 DOI: 10.1002/jca.21630
    In December 2017, 79 delegates attended the 2nd regional plasmapheresis conference and workshop for Southeast Asia (SEA) on the immunomodulatory role of plasma exchange in central and peripheral nervous system disorders in Kuala Lumpur, Malaysia. This meeting featured 6 plenary lectures, interactive sessions dedicated for experience sharing, case presentations, and a practical session for paramedics. Clinical experts and researchers from 7 SEA countries and India shared experience and challenges in treating autoimmune neurological disorders. While the spectrum of diseases and neurology practice remained largely similar, there was great disparities in accessibility of therapeutic plasma exchange (TPE) within SEA countries and between urban or rural settings. Costs, human resources, and healthcare policies are common challenges in providing sustainable TPE services. Novel techniques and innovative ideas in performing TPE were explored. A working consortium comprising of key opinion leaders was proposed to improve standards of TPE and enhance future research.
    Matched MeSH terms: Central Nervous System Diseases/immunology; Central Nervous System Diseases/therapy; Peripheral Nervous System Diseases/immunology; Peripheral Nervous System Diseases/therapy
  10. Zakaria MA, Abdullah JM, George JP, Mutum SS, Lee NN
    Med J Malaysia, 2006 Jun;61(2):229-32.
    PMID: 16898318 MyJurnal
    Third ventricular cavernous angiomas are rare vascular malformations of the brain. We report an eight-year old boy with a rare third ventricular cavernous angioma that hemorrhaged presenting with symptoms of acute hydrocephalus. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) showed a heterogenous ill-defined, solid and cystic intraventricular mass in the third ventricle which was mildly enhanced with contrast and there was associated hydrocephalus. The mass was removed with success and follow up after two years revealed no neurological abnormalities.
    Matched MeSH terms: Central Nervous System Neoplasms/diagnosis*; Central Nervous System Neoplasms/surgery; Hemangioma, Cavernous, Central Nervous System/diagnosis*; Hemangioma, Cavernous, Central Nervous System/surgery
  11. Dang YL, Hor JY, Chia YK, Lim TT, Eow GB
    Acta Neurol Belg, 2014 Sep;114(3):239-41.
    PMID: 23757110 DOI: 10.1007/s13760-013-0217-3
    Matched MeSH terms: Central Nervous System Neoplasms/pathology; Central Nervous System Neoplasms/physiopathology*; Tuberculosis, Central Nervous System/physiopathology*
  12. Deuchars SA, Lall VK, Clancy J, Mahadi M, Murray A, Peers L, et al.
    Exp Physiol, 2018 03 01;103(3):326-331.
    PMID: 29205954 DOI: 10.1113/EP086433
    NEW FINDINGS: What is the topic of this review? This review briefly considers what modulates sympathetic nerve activity and how it may change as we age or in pathological conditions. It then focuses on transcutaneous vagus nerve stimulation, a method of neuromodulation in autonomic cardiovascular control. What advances does it highlight? The review considers the pathways involved in eliciting the changes in autonomic balance seen with transcutaneous vagus nerve stimulation in relationship to other neuromodulatory techniques. The autonomic nervous system, consisting of the sympathetic and parasympathetic branches, is a major contributor to the maintenance of cardiovascular variables within homeostatic limits. As we age or in certain pathological conditions, the balance between the two branches changes such that sympathetic activity is more dominant, and this change in dominance is negatively correlated with prognosis in conditions such as heart failure. We have shown that non-invasive stimulation of the tragus of the ear increases parasympathetic activity and reduces sympathetic activity and that the extent of this effect is correlated with the baseline cardiovascular parameters of different subjects. The effects could be attributable to activation of the afferent branch of the vagus and, potentially, other sensory nerves in that region. This indicates that tragus stimulation may be a viable treatment in disorders where autonomic activity to the heart is compromised.
    Matched MeSH terms: Autonomic Nervous System Diseases/physiopathology*; Sympathetic Nervous System/physiology*; Sympathetic Nervous System/physiopathology
  13. Shabab T, Khanabdali R, Moghadamtousi SZ, Kadir HA, Mohan G
    Int. J. Neurosci., 2017 Jul;127(7):624-633.
    PMID: 27412492 DOI: 10.1080/00207454.2016.1212854
    Activated microglial cells play an important role in immune and inflammatory responses in central nervous system and neurodegenerative diseases. Many pro-apoptotic pathways are mediated by signaling molecules that are produced during neuroinflammation. In glial cells, NF-κB, a transcription factor, initiates and regulates the expression of several inflammatory processes during inflammation which are attributed to the pathology of the several neurodegenerative diseases. In this review, we discuss the most important neuroinflammatory mediators with their pathways. Attenuating cytokines production and controlling microglial inflammatory response, which are the result of understanding neuroinflammation pathways, are considered therapeutic strategies for treating neurodegenerative diseases with an inflammatory component.
    Matched MeSH terms: Nervous System/immunology*; Nervous System/metabolism*
  14. Wong KH, Ng CC, Kanagasabapathy G, Yow YY, Sabaratnam V
    Int J Med Mushrooms, 2017;19(3):191-202.
    PMID: 28605334 DOI: 10.1615/IntJMedMushrooms.v19.i3.10
    Culinary and medicinal mushrooms have been appreciated since prehistoric times as valuable resources for food and medicine. Edible mushrooms represent an untapped source of nutraceuticals and valuable palatable food. Long considered tonics, they are now treasured as functional foods that can improve human health and quality of life. Numerous studies have provided insights into the neuroprotective effects of edible mushrooms, which are attributed to their antioxidant, antineuroinflammatory, and cholinesterase inhibitory properties, and their ability to prevent neuronal death. Here we review the recent literature on the role of culinary and medicinal mushrooms in the management of neurodegenerative diseases and neurotrauma. We highlight some of the molecular mechanisms for how these alternative medicines provide health benefits that could help us to harness their neuroprotective effects.
    Matched MeSH terms: Nervous System; Trauma, Nervous System/therapy*
  15. Viswanathan S, Appiwatanakul M, Nayak A, Islam B, Khatri B, Pangeran D, et al.
    Ther Apher Dial, 2019 Jun;23(3):289-297.
    PMID: 30927331 DOI: 10.1111/1744-9987.12806
    In conjunction with the third regional Southeast Asian (SEA) therapeutic plasma exchange (TPE) conference in Kuala Lumpur, Malaysia, 25 clinicians and researchers from SEA and South Asian countries attended the inaugural strategy meeting for the establishment of a regional TPE consortium for neurological disorders. The primary objective was to establish regional collaboration to improve delivery of TPE services in SEA. A pre-meeting survey was conducted to gather insights on disease spectrum, contextual practice challenges, and the need for a regional TPE consensus. Challenges identified include limited healthcare funding in support of diagnostic workup, TPE therapy, as well as development of clinical infrastructure and expertise capacity building. There was favorable interest in developing a working plan contextualized to this region. Strategies to overcome challenges were discussed. This included the need for a comprehensive referral system and network of regional TPE centers suited to local needs, supported by innovative TPE delivery programs.
    Matched MeSH terms: Nervous System Diseases/diagnosis; Nervous System Diseases/therapy*
  16. Tee TY, Khoo CS, Ibrahim NM, Osman SS
    Neurol India, 2019 3 13;67(1):297-299.
    PMID: 30860142 DOI: 10.4103/0028-3886.253620
    Matched MeSH terms: Nervous System/pathology; Central Nervous System Neoplasms/diagnosis; Central Nervous System Neoplasms/drug therapy*; Central Nervous System Neoplasms/pathology*
  17. Lim CY, Low TH, Sivanoli R, Teh KK, Thuraisingham R
    ANZ J Surg, 2014 Jan-Feb;84(1-2):93-4.
    PMID: 24165375 DOI: 10.1111/ans.12231
    Matched MeSH terms: Peripheral Nervous System Neoplasms/diagnosis*
  18. Choo KE
    Med J Malaysia, 1983 Jun;38(2):167-9.
    PMID: 6621451
    Two cases of Hypomelanosis of Ito are described; presenting with depigmented whorl-like, zig-zag, bizzare cutaneous manifestations associated with central nervous system disorders.
    Matched MeSH terms: Central Nervous System Diseases*
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