MyMedR

Pacemaker infection secondary to burkholderia pseudomallei

Zainal Abidin I, Syed Tamin S, Huat Tan L, Chong WP, Azman W

Pacing Clin Electrophysiol, 2007 Nov;30(11):1420-2.

Infection is a relatively rare but devastating complication of intracardiac device implantation. Burkholderia pseudomallei is the organism which causes melioidosis, an endemic and lethal infection in the tropics. We describe a case of pacemaker infection secondary to Burkholderia pseudomallei, which was treated by explantation of the device and appropriate antimicrobial therapy.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Successful placement of left ventricular pacing lead despite coronary sinus perforation into the pericardial space with an obstructive flap

Tamin SS, Hussin A, Za I, Halmey N, Azman W

Pacing Clin Electrophysiol, 2007 Feb;30(2):276-9.

PMID: 17338728

Coronary sinus perforation is a relatively uncommon but much feared complication that may occur during the placement of left ventricular pacing lead. Coronary sinus perforation, especially in the presence of an obstructive flap, usually indicates the need to abandon the implantation attempt, as there are difficulties in crossing the obstructive flap as well as uncertainty of whether the lead is in the true lumen or into the pericardial space. We describe our experience in successfully placing the left ventricular lead safely despite the problems arising from these circumstances.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Right Ventricular Perforation Caused by a Pacing Catheter Two Weeks After Insertion in a Neonate With Congenital Atrioventricular Block

Ota N, Suzuki R, Latiff HA, Sivalingam S

Ann Thorac Surg, 2015 Oct;100(4):1471.

PMID: 26434454 DOI: 10.1016/j.athoracsur.2015.06.084

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Fulltext Complications of temporary transvenous pacing

Chin K, Singham KT, Anuar M

Med J Malaysia, 1985 Mar;40(1):28-30.

PMID: 3831729

The complications of temporary transvenous endocardial pacing as performed in the University Hospital Kuala Lumpur, from 1971 to 1979 were reviewed. 125 temporary pacings were performed in 111 patients. Different routes of temporary pacing
were used: namely percutaneous subclavian vein and femoral vein puncture and acutecubital vein cutdown. The latter route was associated with a higher incidence of dislodgement and infection. Other common complications encountered were ventricular arrhythymia and generator failure.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Fulltext Long-term performance of a transcatheter pacing system: 12-Month results from the Micra Transcatheter Pacing Study

Duray GZ, Ritter P, El-Chami M, Narasimhan C, Omar R, Tolosana JM, et al.

Heart Rhythm, 2017 05;14(5):702-709.

PMID: 28192207 DOI: 10.1016/j.hrthm.2017.01.035

BACKGROUND: Early performance of the Micra transcatheter pacemaker from the global clinical trial reported a 99.2% implant success rate, low and stable pacing capture thresholds, and a low (4.0%) rate of major complications up to 6 months.

OBJECTIVE: The purpose of this report was to describe the prespecified long-term safety objective of Micra at 12 months and electrical performance through 24 months.

METHODS: The Micra Transcatheter Pacing Study was a prospective single-arm study designed to assess the safety and efficacy of the Micra VVIR leadless/intracardiac pacemaker. Enrolled patients met class I or II guideline recommendations for de novo ventricular pacing. The long-term safety objective was freedom from a system- or procedure-related major complication at 12 months. A predefined historical control group of 2667 patients with transvenous pacemakers was used to compare major complication rates.

RESULTS: The long-term safety objective was achieved with a freedom from major complication rate of 96.0% at 12 months (95% confidence interval 94.2%-97.2%; P < .0001 vs performance goal). The risk of major complications for patients with Micra (N = 726) was 48% lower than that for patients with transvenous systems through 12 months postimplant (hazard ratio 0.52; 95% confidence interval 0.35-0.77; P = .001). Across subgroups of age, sex, and comorbidities, Micra reduced the risk of major complications compared to transvenous systems. Electrical performance was excellent through 24 months, with a projected battery longevity of 12.1 years.

CONCLUSION: Long-term performance of the Micra transcatheter pacemaker remains consistent with previously reported data. Few patients experienced major complications through 12 months of follow-up, and all patient subgroups benefited as compared to transvenous pacemaker historical control group.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Techniques for successful early retrieval of the Micra transcatheter pacing system: A worldwide experience

Afzal MR, Daoud EG, Cunnane R, Mulpuru SK, Koay A, Hussain A, et al.

Heart Rhythm, 2018 06;15(6):841-846.

PMID: 29427820 DOI: 10.1016/j.hrthm.2018.02.008

BACKGROUND: Experience with retrieval of the Micra transcatheter pacing system (TPS) is limited because of its relatively newer technology. Although abandonment of the TPS at end of life is recommended, certain situations such as endovascular infection or device embolization warrant retrieval.

OBJECTIVE: The purpose of this study was to report the worldwide experience with successful retrieval of the Micra TPS.

METHODS: A list of all successful retrievals of the currently available leadless pacemakers (LPs) was obtained from the manufacturer of Micra TPS. Pertinent details of retrieval, such as indication, days postimplantation, equipment used, complications, and postretrieval management, were obtained from the database collected by the manufacturer. Other procedural details were obtained directly from the operators at each participating site.

RESULTS: Data from the manufacturer consisted of 40 successful retrievals of the Micra TPS. Operators for 29 retrievals (73%) provided the consent and procedural details. Of the 29 retrievals, 11 patients underwent retrieval during the initial procedure (immediate retrieval); the other 18 patients underwent retrieval during a separate procedure (delayed retrieval). Median duration before delayed retrieval was 46 days (range 1-95 days). The most common reason for immediate retrieval was elevated pacing threshold after tether removal. The most common reasons for delayed retrieval included elevated pacing threshold at follow-up, endovascular infection, and need for transvenous device. Mean procedure duration was 63.11 ± 56 minutes. All retrievals involved snaring via a Micra TPS delivery catheter or steerable sheath. No serious complications occurred during the reported retrievals.

CONCLUSION: Early retrieval of the Micra TPS is feasible and safe.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

Fulltext Splenic amyloidosis: a rare cause of spontaneous splenic rupture

Chan RS, Abdul Aziz YF, Chandran P, Ng EK

Singapore Med J, 2011 Nov;52(11):e232-5.

PMID: 22173263

A 62 year-old woman who presented with an atraumatic acute abdomen was discovered to have haemoperitoneum with splenic rupture on urgent computed tomography and was immediately referred for life-saving emergency splenectomy. Histopathological examination revealed secondary splenic amyloidosis. The patient was later found to be suffering from infective endocarditis secondary to her permanent cardiac pacemaker. This report describes a patient who could have suffered from a long-standing infected vegetation on a permanent cardiac pacemaker, which led to splenic amyloidosis and spontaneous splenic rupture.

Matched MeSH terms: Pacemaker, Artificial/adverse effects

Bilateral central vein stenosis in a dialysis patient with a pacemaker

Yew KL, Anderson S, Farah R, Lim SH

Asian Cardiovasc Thorac Ann, 2014 Oct;22(8):979-80.

PMID: 24887840 DOI: 10.1177/0218492313491583

Central vein stenosis is not uncommon in hemodialysis-dependent patients as a result of mechanical damage to the vessel walls from prior cannulation. It can cause ipsilateral upper limb swelling and pain, resulting in suboptimal hemodialysis. It is unfortunate for bilateral central vein stenosis to develop concomitantly, and rare in the setting of an in-situ pacemaker. This case illustrates the successful ligation of a nondependent left arteriovenous fistula and stenting of the right subclavian vein with functioning ipsilateral arteriovenous fistula, to overcome the problem of symptomatic bilateral upper limb swelling.

Matched MeSH terms: Pacemaker, Artificial/adverse effects*

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