Displaying all 11 publications

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  1. Haridas G
    Matched MeSH terms: Thiamine Deficiency
  2. Hor ESL, Singh GP, Omar NA, Russell V
    BMJ Case Rep, 2021 Aug 05;14(8).
    PMID: 34353834 DOI: 10.1136/bcr-2021-244082
    We report the case of a middle-aged woman with a history of bipolar disorder, in the absence of alcohol or substance misuse. The patient had been maintained on fluphenazine decanoate depot and now presented acutely with cognitive dysfunction and rigidity. Laboratory tests revealed elevated creatine kinase, acute kidney injury with metabolic acidosis and transaminitis, leading to a provisional diagnosis of neuroleptic malignant syndrome (NMS). Neuroleptics were withheld; dialysis was commenced; and blood biochemistry parameters improved in tandem. However, mental status changes persisted, and re-evaluation revealed multidirectional nystagmus with bilateral past-pointing. MRI confirmed the diagnosis of Wernicke's encephalopathy (WE). Prompt recovery followed treatment with high-dose intravenous thiamine. We discuss the co-occurrence of NMS and non-alcoholic WE-highlighting the need for a high index of suspicion for these relatively rare neuropsychiatric diagnoses which are often missed in those with atypical presentations.
    Matched MeSH terms: Thiamine Deficiency*
  3. Eijkman C
    Ned Tijdschr Geneeskd, 1990 Aug 25;134(34):1654-7.
    PMID: 2215709
    Matched MeSH terms: Thiamine Deficiency/history
  4. Ghaffar ZA, Chong SE, Tan KL, Appalanaido GK, Musa MY, Hussin HB, et al.
    J Contemp Brachytherapy, 2018 Dec;10(6):573-576.
    PMID: 30662482 DOI: 10.5114/jcb.2018.79856
    The practice of brachytherapy in unresectable tongue carcinoma is gaining popularity. However, this procedure poses specific anesthetic challenges, particularly challenges of airway sharing and a higher rate of difficult airway. We report a 74-year-old chronic smoker, chronic alcoholic with history of stroke, who had undergone brachytherapy for tongue carcinoma. Apart from a huge tongue tumor, he had an epiglottic mass but refused elective tracheostomy. This had led to a few critical states throughout the process of treatment, including a metabolic crisis due to thiamine deficiency and difficult airway crisis. To our best knowledge, there have been no reported case on a patient with vocal cord mass undergoing tongue brachytherapy. We hope sharing of this experience may aid the management of similar patients in future.
    Matched MeSH terms: Thiamine Deficiency
  5. Matched MeSH terms: Thiamine Deficiency
  6. Chong YH, Ho GS
    Am J Clin Nutr, 1970 Mar;23(3):261-6.
    PMID: 5436634 DOI: 10.1093/ajcn/23.3.261
    Matched MeSH terms: Thiamine Deficiency/diagnosis; Thiamine Deficiency/drug therapy; Thiamine Deficiency/enzymology
  7. Fozi K, Azmi H, Kamariah H, Azwa MS
    Med J Malaysia, 2006 Dec;61(5):519-25.
    PMID: 17623950 MyJurnal
    A possible outbreak of beriberi occurred at a drug detention and rehabilitation centre, Pusat Serenti Bukit Cabang, Perlis, Malaysia in February 2004. This outbreak was identified following the presentation of a large number of inmates at a health centre with signs and symptoms of ankle oedema and shortness of breath. Further investigations revealed the death of three inmates at the General Hospital with similar clinical presentations during the period from October 2003 till February 2004. A cross sectional comparative study was carried out at the rehabilitation centre to find out the prevalence of thiamine deficiency among the inmates both symptomatic and asymptomatic. A total of 154 inmates were examined (57 symptomatic and 97 asymptomatic cases). It was found that 74% from the sample study (114 cases) had thiamine deficiency (44 symptomatic and 70 asymptomatic). Further statistical analysis showed that ankle oedema is consistent with the diagnosis of thiamine deficiency but lack sensitivity (p < 0.05, sensitivity 24.6%, specificity 95%). This outbreak could have been triggered by poor diet intake of thiamine by the inmates coupled with possible intake of certain thiamine antagonists in their diet.
    Matched MeSH terms: Thiamine Deficiency/epidemiology*
  8. Jeyakumar D
    Med J Malaysia, 1995 Mar;50(1):17-20.
    PMID: 7752970
    Twenty-seven inmates from a detention centre in Perak were evaluated for possible causes of their ankle oedema. Physical examination and biochemical evaluation did not show any evidence of renal or hepatic dysfunction. The cardiac origin of their problem was suggested by the presence of other signs of heart failure in three of them and by radiological evidence of cardiomegaly in 40% of them. All the patients who returned for review demonstrated a prompt clinical response to thiamine replacement therapy.
    Matched MeSH terms: Thiamine Deficiency/complications
  9. THARMARATNAM A
    Med J Malaysia, 1963 Sep;18:52-8.
    PMID: 14064299
    Matched MeSH terms: Thiamine Deficiency*
  10. Kandiah N, Boo LJ
    Med J Malaysia, 1977 Jun;31(4):270-6.
    PMID: 412038
    Matched MeSH terms: Thiamine Deficiency/epidemiology
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