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  1. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2018;78(4):291.
    PMID: 31007582 DOI: 10.1140/epjc/s10052-018-5740-1
    A search for new physics in events with a Z boson produced in association with large missing transverse momentum at the LHC is presented. The search is based on the 2016 data sample of proton-proton collisions recorded with the CMS experiment at


    s

    =
    13

    TeV

    , corresponding to an integrated luminosity of 35.9



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    -
    1



    . The results of this search are interpreted in terms of a simplified model of dark matter production via spin-0 or spin-1 mediators, a scenario with a standard-model-like Higgs boson produced in association with the Z boson and decaying invisibly, a model of unparticle production, and a model with large extra spatial dimensions. No significant deviations from the background expectations are found, and limits are set on relevant model parameters, significantly extending the results previously achieved in this channel.
  2. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(1):20.
    PMID: 30872964 DOI: 10.1140/epjc/s10052-018-6482-9
    Measurements of inclusive isolated-photon and photon+jet production in proton-proton collisions at


    s

    =
    13

    TeV

    are presented. The analysis uses data collected by the CMS experiment in 2015, corresponding to an integrated luminosity of 2.26



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    1



    . The cross section for inclusive isolated photon production is measured as a function of the photon transverse energy in a fiducial region. The cross section for photon+jet production is measured as a function of the photon transverse energy in the same fiducial region with identical photon requirements and with the highest transverse momentum jet. All measurements are in agreement with predictions from next-to-leading-order perturbative QCD.
  3. Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Bergauer T, Dragicevic M, et al.
    Eur Phys J C Part Fields, 2015;75(5):212.
    PMID: 25999783
    Properties of the Higgs boson with mass near 125[Formula: see text] are measured in proton-proton collisions with the CMS experiment at the LHC. Comprehensive sets of production and decay measurements are combined. The decay channels include [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] pairs. The data samples were collected in 2011 and 2012 and correspond to integrated luminosities of up to 5.1[Formula: see text] at 7[Formula: see text] and up to 19.7[Formula: see text] at 8[Formula: see text]. From the high-resolution [Formula: see text] and [Formula: see text] channels, the mass of the Higgs boson is determined to be [Formula: see text]. For this mass value, the event yields obtained in the different analyses tagging specific decay channels and production mechanisms are consistent with those expected for the standard model Higgs boson. The combined best-fit signal relative to the standard model expectation is [Formula: see text] at the measured mass. The couplings of the Higgs boson are probed for deviations in magnitude from the standard model predictions in multiple ways, including searches for invisible and undetected decays. No significant deviations are found.
  4. Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Bergauer T, Dragicevic M, et al.
    Eur Phys J C Part Fields, 2015;75(5):235.
    PMID: 26069461
    Results are presented from a search for particle dark matter (DM), extra dimensions, and unparticles using events containing a jet and an imbalance in transverse momentum. The data were collected by the CMS detector in proton-proton collisions at the LHC and correspond to an integrated luminosity of 19.7[Formula: see text]at a centre-of-mass energy of 8[Formula: see text]. The number of observed events is found to be consistent with the standard model prediction. Limits are placed on the DM-nucleon scattering cross section as a function of the DM particle mass for spin-dependent and spin-independent interactions. Limits are also placed on the scale parameter [Formula: see text] in the Arkani-Hamed, Dimopoulos, and Dvali (ADD) model of large extra dimensions, and on the unparticle model parameter [Formula: see text]. The constraints on ADD models and unparticles are the most stringent limits in this channel and those on the DM-nucleon scattering cross section are an improvement over previous collider results.
  5. Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2017;77(5):294.
    PMID: 28579921 DOI: 10.1140/epjc/s10052-017-4787-8
    A search for new phenomena is performed in final states containing one or more jets and an imbalance in transverse momentum in pp collisions at a centre-of-mass energy of 13[Formula: see text]. The analysed data sample, recorded with the CMS detector at the CERN LHC, corresponds to an integrated luminosity of 2.3[Formula: see text]. Several kinematic variables are employed to suppress the dominant background, multijet production, as well as to discriminate between other standard model and new physics processes. The search provides sensitivity to a broad range of new-physics models that yield a stable weakly interacting massive particle. The number of observed candidate events is found to agree with the expected contributions from standard model processes, and the result is interpreted in the mass parameter space of fourteen simplified supersymmetric models that assume the pair production of gluinos or squarks and a range of decay modes. For models that assume gluino pair production, masses up to 1575 and 975[Formula: see text] are excluded for gluinos and neutralinos, respectively. For models involving the pair production of top squarks and compressed mass spectra, top squark masses up to 400[Formula: see text] are excluded.
  6. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2018;78(9):789.
    PMID: 30956565 DOI: 10.1140/epjc/s10052-018-6242-x
    A search is presented for physics beyond the standard model, based on measurements of dijet angular distributions in proton-proton collisions at


    s

    =
    13
    TeV

    . The data collected with the CMS detector at the LHC correspond to an integrated luminosity of 35.9



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    -
    1



    . The observed distributions, corrected to particle level, are found to be in agreement with predictions from perturbative quantum chromodynamics that include electroweak corrections. Constraints are placed on models containing quark contact interactions, extra spatial dimensions, quantum black holes, or dark matter, using the detector-level distributions. In a benchmark model where only left-handed quarks participate, contact interactions are excluded at the 95% confidence level up to a scale of 12.8 or 17.5TeV, for destructive or constructive interference, respectively. The most stringent lower limits to date are set on the ultraviolet cutoff in the Arkani-Hamed-Dimopoulos-Dvali model of extra dimensions. In the Giudice-Rattazzi-Wells convention, the cutoff scale is excluded up to 10.1TeV. The production of quantum black holes is excluded for masses below 5.9 and 8.2TeV, depending on the model. For the first time, lower limits between 2.0 and 4.6TeVare set on the mass of a dark matter mediator for (axial-)vector mediators, for the universal quark coupling


    g
    q

    =
    1.0

    .
  7. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2018;78(11):965.
    PMID: 30881214 DOI: 10.1140/epjc/s10052-018-6373-0
    The production of a
    Z
    boson, decaying to two charged leptons, in association with jets in proton-proton collisions at a centre-of-mass energy of 13


    TeV

    is measured. Data recorded with the CMS detector at the LHC are used that correspond to an integrated luminosity of 2.19



    fb
    -1


    . The cross section is measured as a function of the jet multiplicity and its dependence on the transverse momentum of the
    Z
    boson, the jet kinematic variables (transverse momentum and rapidity), the scalar sum of the jet momenta, which quantifies the hadronic activity, and the balance in transverse momentum between the reconstructed jet recoil and the
    Z
    boson. The measurements are compared with predictions from four different calculations. The first two merge matrix elements with different parton multiplicities in the final state and parton showering, one of which includes one-loop corrections. The third is a fixed-order calculation with next-to-next-to-leading order accuracy for the process with a
    Z
    boson and one parton in the final state. The fourth combines the fully differential next-to-next-to-leading order calculation of the process with no parton in the final state with next-to-next-to-leading logarithm resummation and parton showering.
  8. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(5):444.
    PMID: 31265003 DOI: 10.1140/epjc/s10052-019-6926-x
    A search for supersymmetry is presented based on events with at least one photon, jets, and large missing transverse momentum produced in proton-proton collisions at a center-of-mass energy of 13



    Te



    . The data correspond to an integrated luminosity of 35.9



    fb

    -
    1



    and were recorded at the LHC with the CMS detector in 2016. The analysis characterizes signal-like events by categorizing the data into various signal regions based on the number of jets, the number of
    b
    -tagged jets, and the missing transverse momentum. No significant excess of events is observed with respect to the expectations from standard model processes. Limits are placed on the gluino and top squark pair production cross sections using several simplified models of supersymmetric particle production with gauge-mediated supersymmetry breaking. Depending on the model and the mass of the next-to-lightest supersymmetric particle, the production of gluinos with masses as large as 2120



    Ge



    and the production of top squarks with masses as large as 1230



    Ge



    are excluded at 95% confidence level.
  9. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(7):564.
    PMID: 31397444 DOI: 10.1140/epjc/s10052-019-7058-z
    A search is presented for a heavy pseudoscalar boson
    A
    decaying to a Z  boson and a Higgs boson with mass of 125


    GeV

    . In the final state considered, the Higgs boson decays to a bottom quark and antiquark, and the Z  boson decays either into a pair of electrons, muons, or neutrinos. The analysis is performed using a data sample corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    collected in 2016 by the CMS experiment at the LHC from proton-proton collisions at a center-of-mass energy of 13



    Te



    . The data are found to be consistent with the background expectations. Exclusion limits are set in the context of two-Higgs-doublet models in the
    A
    boson mass range between 225 and 1000


    GeV

    .
  10. Ramli ZAC, Kamarudin SK
    Nanoscale Res Lett, 2018 Dec 22;13(1):410.
    PMID: 30578446 DOI: 10.1186/s11671-018-2799-4
    Platinum (Pt)-based nanoparticle metals have received a substantial amount of attention and are the most popular catalysts for direct methanol fuel cell (DMFC). However, the high cost of Pt catalysts, slow kinetic oxidation, and the formation of CO intermediate molecules during the methanol oxidation reaction (MOR) are major challenges associate with single-metal Pt catalysts. Recent studies are focusing on using either Pt alloys, such as Fe, Ni, Co, Rh, Ru, Co, and Sn metals, or carbon support materials to enhance the catalytic performance of Pt. In recent years, Pt and Pt alloy catalysts supported on great potential of carbon materials such as MWCNT, CNF, CNT, CNC, CMS, CNT, CB, and graphene have received remarkable interests due to their significant properties that can contribute to the excellent MOR and DMFC performance. This review paper summaries the development of the above alloys and support materials related to reduce the usage of Pt, improve stability, and better electrocatalytic performance of Pt in DMFC. Finally, discussion of each catalyst and support in terms of morphology, electrocatalytic activity, structural characteristics, and its fuel cell performance are presented.
  11. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(2):90.
    PMID: 30814908 DOI: 10.1140/epjc/s10052-019-6556-3
    A search is presented for the single production of vector-like quarks in proton-proton collisions at


    s

    =
    13

    TeV

    . The data, corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    , were recorded with the CMS experiment at the LHC. The analysis focuses on the vector-like quark decay into a top quark and a
    W
    boson, with one muon or electron in the final state. The mass of the vector-like quark candidate is reconstructed from hadronic jets, the lepton, and the missing transverse momentum. Methods for the identification of
    b
    quarks and of highly Lorentz boosted hadronically decaying top quarks and
    W
    bosons are exploited in this search. No significant deviation from the standard model background expectation is observed. Exclusion limits at 95% confidence level are set on the product of the production cross section and branching fraction as a function of the vector-like quark mass, which range from 0.3 to 0.03


    pb

    for vector-like quark masses of 700 to 2000


    GeV

    . Mass exclusion limits up to 1660


    GeV

    are obtained, depending on the vector-like quark type, coupling, and decay width. These represent the most stringent exclusion limits for the single production of vector-like quarks in this channel.
  12. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(2):123.
    PMID: 30863200 DOI: 10.1140/epjc/s10052-019-6620-z
    Measurements of normalized differential cross sections as functions of the multiplicity and kinematic variables of charged-particle tracks from the underlying event in top quark and antiquark pair production are presented. The measurements are performed in proton-proton collisions at a center-of-mass energy of 13



    Te



    , and are based on data collected by the CMS experiment at the LHC in 2016 corresponding to an integrated luminosity of 35.9



    fb

    -
    1



    . Events containing one electron, one muon, and two jets from the hadronization and fragmentation of
    b
    quarks are used. These measurements characterize, for the first time, properties of the underlying event in top quark pair production and show no deviation from the universality hypothesis at energy scales typically above twice the top quark mass.
  13. Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, et al.
    Eur Phys J C Part Fields, 2019;79(3):280.
    PMID: 31007587 DOI: 10.1140/epjc/s10052-019-6730-7
    A search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks is performed in proton-proton collisions at a center-of-mass energy of 13



    Te



    collected with the CMS detector at the LHC. The analyzed data sample corresponds to an integrated luminosity of 35.9



    fb

    -
    1



    . The signal is characterized by a large missing transverse momentum recoiling against a bottom quark-antiquark system that has a large Lorentz boost. The number of events observed in the data is consistent with the standard model background prediction. Results are interpreted in terms of limits both on parameters of the type-2 two-Higgs doublet model extended by an additional light pseudoscalar boson
    a
    (2HDM+
    a
    ) and on parameters of a baryonic


    Z

    '

    simplified model. The 2HDM+
    a
    model is tested experimentally for the first time. For the baryonic


    Z

    '

    model, the presented results constitute the most stringent constraints to date.
  14. Deris ZZ
    Malays J Med Sci, 2015 Sep;22(5):1-6.
    PMID: 28239263
    The global emergence and dissemination of multidrug-resistant Gram-negative superbugs, particularly carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae, lead to the limited effectiveness of antibiotics for treating nosocomial infections. In most cases, polymyxins are the last resort therapy, and these antibiotics must be used intelligently to prolong their efficacy in clinical practice. Polymyxin B and colistin (polymyxin E) were introduced prior to modern drug regulation, and the majority of the 'old' drug information is unreliable. Recent pharmacokinetic data do not support the renal dose adjustment of intravenous (IV) polymyxin B as suggested by the manufacturer, and this drug must be scaled by the total body weight. Whereas IV colistin is formulated as an inactive prodrug, colistin methanesulfonate (CMS) has different pharmacokinetic profiles than polymyxin B. To achieve maximum efficacy, CMS should be administered as a loading dose scaled to body weight and a maintenance dose according to the renal profiles. Polymyxin combination therapy is suggested due to a sub-therapeutic plasma concentration in a significant proportion of patients and a high incidence of polymyxin hetero-resistance among Gram-negative superbugs. In conclusion, polymyxins must be reserved as a last resort and should be wisely used when truly indicated.
  15. Raihan R, Tabassum S, Al-Mahtab M, Nessa A, Jahan M, Shamim Kabir CM, et al.
    Euroasian J Hepatogastroenterol, 2015 Jan-Jun;5(1):7-10.
    PMID: 29201677 DOI: 10.5005/jp-journals-10018-1120
    Background: Hepatitis B virus (HBV) infection has many faces. Precore and core promoter mutants resemble inactive carrier status. The identification of hepatitis B core antigen (HBcAg) in hepatocytes may have variable clinical significance. The present study was undertaken to detect HBcAg in chronic hepatitis B (CHB) patients and to assess the efficacy of detection system by indirect immunofluorescence (IIF) and indirect immunoperoxidase (IIP).

    Materials and methods: The study was done in 70 chronic HBV-infected patients. Out of 70 patients, eight (11.4%) were hepatitis B e antigen (HBeAg) positive and 62 (88.57%) were HBeAg negative. Hepatitis B core antigen was detected by indirect immunofluorescence (IIF) and indirect immunoperoxidase (IIP) methods in liver tissue.

    Results: All HBeAg positive patients expressed HBcAg by both IIF and IIP methods. Out of 62 patients with HBeAg-negative CHB, HBcAg was detected by IIF in 55 (88.7%) patients and by IIP in 51 (82.26%) patients. A positive relation among viral load and HBcAg detection was also found. This was more evident in the case of HBeAg negative patients and showed a positive relation with HBV DNA levels.

    Conclusion: Hepatitis B core antigen can be detected using the IIF from formalin fixed paraffin block preparation and also by IIP method. This seems to reflect the magnitudes of HBV replication in CHB.

    How to cite this article: Raihan R, Tabassum S, Al-Mahtab M, Nessa A, Jahan M, Kabir CMS, Kamal M, Aguilar JC. Hepatitis B Core Antigen in Hepatocytes of Chronic Hepatitis B: Comparison between Indirect Immunofluorescence and Immunoperoxidase Method. Euroasian J Hepato-Gastroenterol 2015;5(1):7-10.
  16. Almahdi EM, Zaidan AA, Zaidan BB, Alsalem MA, Albahri OS, Albahri AS
    J Med Syst, 2019 Jun 06;43(7):219.
    PMID: 31172296 DOI: 10.1007/s10916-019-1339-9
    This study presents a prioritisation framework for mobile patient monitoring systems (MPMSs) based on multicriteria analysis in architectural components. This framework selects the most appropriate system amongst available MPMSs for the telemedicine environment. Prioritisation of MPMSs is a challenging task due to (a) multiple evaluation criteria, (b) importance of criteria, (c) data variation and (d) unmeasurable values. The secondary data presented as the decision evaluation matrix include six systems (namely, Yale-National Aeronautics and Space Administration (NASA), advanced health and disaster aid network, personalised health monitoring, CMS, MobiHealth and NTU) as alternatives and 13 criteria (namely, supported number of sensors, sensor front-end (SFE) communication, SFE to mobile base unit (MBU) communications, display of biosignals on the MBU, storage of biosignals on the MBU, intra-body area network (BAN) communication problems, extra-BAN communication problems, extra-BAN communication technology, extra-BAN communication protocols, back-end system communication technology, intended geographic area of use, end-to-end security and reported trial problems) based on the architectural components of MPMSs. These criteria are adopted from the most relevant studies and are found to be applicable to this study. The prioritisation framework is developed in three stages. (1) The unmeasurable values of the MPMS evaluation criteria in the adopted decision evaluation matrix based on expert opinion are represented by using the best-worst method (BWM). (2) The importance of the evaluation criteria based on the architectural components of the MPMS is determined by using the BWM. (3) The VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) method is utilised to rank the MPMSs according to the determined importance of the evaluation criteria and the adopted decision matrix. For validation, mean ± standard deviation is used to verify the similarity of systematic prioritisations objectively. The following results are obtained. (1) The BWM represents the unmeasurable values of the MPMS evaluation criteria. (2) The BWM is suitable for weighing the evaluation criteria based on the architectural components of the MPMS. (3) VIKOR is suitable for solving the MPMS prioritisation problem. Moreover, the internal and external VIKOR group decision making are approximately the same, with the best MPMS being 'Yale-NASA' and the worst MPMS being 'NTU'. (4) For the objective validation, remarkable differences are observed between the group scores, which indicate the similarity of internal and external prioritisation results.
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