Displaying publications 1 - 20 of 249 in total

  1. Musa RH, Muhamad NA, Hassan A, Ayob Y, Yusoff NM
    Asian J Transfus Sci, 2015 Jan-Jun;9(1):48-54.
    PMID: 25722573 DOI: 10.4103/0973-6247.150951
    Rh molecular studies have been previously mainly conducted in Caucasians and African population. There is a limited data on the molecular basis for Rh genotypes among Asians.
    Matched MeSH terms: European Continental Ancestry Group
  2. Black K
    Malayan Medical Journal, 1932;7:99-107.
    Matched MeSH terms: European Continental Ancestry Group
  3. Scott GW
    Matched MeSH terms: European Continental Ancestry Group
    J R Army Med Corps, 1963;109:223-7.
    PMID: 14078072
    Matched MeSH terms: European Continental Ancestry Group*
  5. Wardahanisah Razali, Rusmadiah Anwar
    It is hard to identify the local Malay identity in a design context compared to other cultural oriented design in several countries. This paper tries to uncover how designers interpret local identity embodied agent based on local items influences and understood and the influence of incremental, radical design that changes respective to preceding designs. A descriptive study through the literature reviews focusses on a type of artefact initiated through cultural-oriented design. Based on the preliminary study, a sampling taken from the Chinese, Indian, Japanese or European consistently apply the same fundamental understanding in regards to the culture-oriented design. From the same point of view, teapot seems to be used as one of the dominant artefact indicating the design preferences. This research will benefit both the academia and the industry and identify significant identity based on the local context and become an embodied agent to give impact in establishing the state-of-the-art of brand, the identity of local design, establish new trademark towards generating domestic, international economy and promote the nation worldwide throughout design platform.
    Matched MeSH terms: European Continental Ancestry Group
  6. Ang KC, Ngu MS, Reid KP, Teh MS, Aida ZS, Koh DX, et al.
    PLoS ONE, 2012;7(8):e42752.
    PMID: 22912732 DOI: 10.1371/journal.pone.0042752
    Pigmentation is a readily scorable and quantitative human phenotype, making it an excellent model for studying multifactorial traits and diseases. Convergent human evolution from the ancestral state, darker skin, towards lighter skin colors involved divergent genetic mechanisms in people of European vs. East Asian ancestry. It is striking that the European mechanisms result in a 10-20-fold increase in skin cancer susceptibility while the East Asian mechanisms do not. Towards the mapping of genes that contribute to East Asian pigmentation there is need for one or more populations that are admixed for ancestral and East Asian ancestry, but with minimal European contribution. This requirement is fulfilled by the Senoi, one of three indigenous tribes of Peninsular Malaysia collectively known as the Orang Asli. The Senoi are thought to be an admixture of the Negrito, an ancestral dark-skinned population representing the second of three Orang Asli tribes, and regional Mongoloid populations of Indo-China such as the Proto-Malay, the third Orang Asli tribe. We have calculated skin reflectance-based melanin indices in 492 Orang Asli, which ranged from 28 (lightest) to 75 (darkest); both extremes were represented in the Senoi. Population averages were 56 for Negrito, 42 for Proto-Malay, and 46 for Senoi. The derived allele frequencies for SLC24A5 and SLC45A2 in the Senoi were 0.04 and 0.02, respectively, consistent with greater South Asian than European admixture. Females and individuals with the A111T mutation had significantly lighter skin (p = 0.001 and 0.0039, respectively). Individuals with these derived alleles were found across the spectrum of skin color, indicating an overriding effect of strong skin lightening alleles of East Asian origin. These results suggest that the Senoi are suitable for mapping East Asian skin color genes.
    Matched MeSH terms: European Continental Ancestry Group/ethnology; European Continental Ancestry Group/genetics
  7. Thambu J
    Med J Malaya, 1966 Sep;21(1):49-52.
    PMID: 4224878
    Matched MeSH terms: European Continental Ancestry Group
  8. Tan DS
    Med J Malaya, 1967 Jun;21(4):358-61.
    PMID: 4230504
    Matched MeSH terms: European Continental Ancestry Group
  9. Suzy Aziziyana Saili, Rosila Bee Mohd Hussain, Khairulnizam Mat Karim
    A plural society existence due to economic policy is an outcome of foreign colonization. Due to the
    British economic policy, Malaya saw the influx two foreign ethnic; Chinese and Indian, working in tin
    mining and rubber estates respectively. Early conflict involving the Malays and these foreign workers
    is inevitable which is evident during both the Japanese intervention and the British colonization. The
    objective of this paper is to review the role and responsibilities of Communities Liaison Committee in
    pioneering social cohesion between the three main ethnics in Malaya during the crucial time of
    Japanese intervention, British colonization, communist threat and the declaration of emergency. Before
    CLC, a cooperation was initiated by AMCJA-PUTERA coalition but was short lived due to the absence
    of support from the British and lack of bargaining between Malays and Non-Malays. CLC received a
    full patronage of the British as the pioneer of social cohesion in Malaya, especially when it was able to call upon the three main ethnic in its discussion of bargaining and negotiation or what is widely known
    as the social contract, as well as practicing political power sharing.
    Matched MeSH terms: European Continental Ancestry Group
  10. Chen SL
    Matched MeSH terms: European Continental Ancestry Group
  11. Tan KW, Stephen ID
    Front Psychol, 2019;10:1352.
    PMID: 31275195 DOI: 10.3389/fpsyg.2019.01352
    Facial skin color influences the perceived health and attractiveness of Caucasian faces, and has been proposed as a valid cue to aspects of physiological health. Similar preferences for skin color have previously been found in African participants, while different preferences have been found among mainland Chinese participants. Here, we asked Malaysian Chinese participants (ethnic Chinese living in an Asian country with high levels of exposure to Western culture) to manipulate the skin color of Malaysian Chinese, Caucasian, and African faces to make them "look as healthy as possible." Participants chose to increase skin yellowness to a greater extent than to increase skin redness to optimize healthy appearance. The slight reduction in skin lightness chosen was not statistically significant after correction for multiple comparisons. While broadly in line with the preferences of Caucasian and African participants from previous studies, this differs from mainland Chinese participants. There may be a role for culture in skin color preferences, though methodological differences mean that further research is necessary to identify the cause of these differences in preferences.
    Matched MeSH terms: European Continental Ancestry Group
  12. Li H, Teo YY, Tan EK
    Mov. Disord., 2015 Sep;30(10):1335-42.
    PMID: 25758099 DOI: 10.1002/mds.26176
    Reproducing genomewide association studies findings in different populations is challenging, because the reproducibility fundamentally relies on the similar patterns of linkage disequilibrium between the unknown causal variants and the genotyped single-nucleotide polymorphisms (SNPs).
    Matched MeSH terms: European Continental Ancestry Group/genetics*
  13. Hawkins R
    Clin. Chim. Acta, 2011 May 12;412(11-12):1167.
    PMID: 21396354 DOI: 10.1016/j.cca.2011.03.003
    Matched MeSH terms: European Continental Ancestry Group*
  14. Hawkins RC
    Clin. Chim. Acta, 2010 Sep 6;411(17-18):1393.
    PMID: 20580697 DOI: 10.1016/j.cca.2010.05.027
    Matched MeSH terms: European Continental Ancestry Group*
  15. Ismail R
    J Postgrad Med, 2006 Oct-Dec;52(4):245.
    PMID: 17243206
    Matched MeSH terms: European Continental Ancestry Group/genetics*
  16. Chang YM, Perumal R, Keat PY, Yong RY, Kuehn DL, Burgoyne L
    Forensic Sci. Int., 2007 Mar 2;166(2-3):115-20.
    PMID: 16765004
    The use of STR multiplexes with the incorporated gender marker Amelogenin is common practice in forensic DNA analysis. However, when a known male sample shows a dropout of the Amelogenin Y-allele, the STR system falsely genotypes it as a female. To date, our laboratory has observed 18 such cases: 12 from our Y-STR database and six from casework. A study on 980 male individuals in the Malaysian population using the AmpFlSTR Y-filer has revealed a distinct Y-chromosome haplotype associated with the Amelogenin nulls. Our results showed that whilst the Amelogenin nulls were noticeably absent among the Chinese, both the Indians and Malays exhibited such mutations at 3.2 and 0.6%, respectively. It was also found that the Amelogenin negative individuals predominantly belonged to the J2e lineage, suggesting the possibility of a common ancestor for at least some of these chromosomes. The null frequencies showed concordance with the data published in Chang et al. [Higher failures of Amelogenin sex test in an Indian population group, J. Forensic Sci. 48 (2003) 1309-1313] on a smaller Malaysian population of 338 males which used a Y-STR triplex. In the current study, apart from the absence of the Amelogenin Y-locus, a complete absence of the DYS458 locus in all the nulls was also observed. This study together with the 2003 study has indicated a similar deletion region exists on the Y(p)11.2 band in all the 18 Y-chromosomes. Using bioinformatics, this deletion has been mapped to a region of at least 1.13 Mb on the Y(p)11.2 encompassing the Amelogenin, MSY1 minisatellite and DYS458 locus. Further, the Y-filer haplotypes revealed an additional null at Y-GATA H4 in two of the Indian males presented here.
    Matched MeSH terms: European Continental Ancestry Group/genetics
  17. Zainuddin Z, Teh LK, Suhaimi AW, Ismail R
    J Clin Pharm Ther, 2006 Apr;31(2):187-91.
    PMID: 16635054
    CYP2C9 is one of the major drug metabolizing enzymes for many drugs including warfarin, NSAIDs and losartan. It is polymorphic in many populations. Data on the distribution of CYP2C9 and the implication of CYP2C9 polymorphism in the Malaysian population is lacking. Our objectives were therefore to investigate the prevalence of CYP2C9 variants among unrelated healthy volunteers of Malays, Chinese and Indians in Malaysia.
    Matched MeSH terms: European Continental Ancestry Group/genetics
  18. Loh HC, Tang PY, Tee SF, Chow TJ, Choong CY, Lim SY, et al.
    Psychiatry Res, 2013 Jul 30;208(2):186-8.
    PMID: 23489597 DOI: 10.1016/j.psychres.2013.01.022
    Neuregulin-1 is widely investigated due to its hypothesised association with schizophrenia. Single-nucleotide polymorphisms rs764059, rs2954041 and rs3924999 were investigated (417 patients with schizophrenia and 429 controls). We failed to demonstrate a significant association between rs2954041 and rs3924999 with schizophrenia in the three ethnic groups studied (Malay, Chinese, and Indian), while rs764059 was found to be monomorphic.
    Matched MeSH terms: European Continental Ancestry Group/genetics
  19. Ismail R, Teh LK
    Eur. J. Clin. Pharmacol., 2001 Oct;57(8):617-8.
    PMID: 11758642
    Matched MeSH terms: European Continental Ancestry Group/genetics*
  20. Kwon S, Bower C, English D
    PMID: 14565623
    Birth defects in infants born to non-Caucasian, non-Indigenous mothers in Australia have not been described in detail previously.
    Matched MeSH terms: European Continental Ancestry Group/statistics & numerical data*
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