Displaying all 10 publications

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  1. Chiun KC, Tang IP, Tharumalingam V, Nurshaline Pauline HK
    Med J Malaysia, 2012 Feb;67(1):131-2.
    PMID: 22582569 MyJurnal
    To report an unusual location of infrasellar craniopharyngioma in a peadiatric patient.
    Matched MeSH terms: Pituitary Neoplasms/surgery
  2. Mallina S, Harvinder S, Rosalind S, Philip R, Gurdeep S, Anil S
    Med J Malaysia, 2006 Aug;61(3):320-2.
    PMID: 17240583 MyJurnal
    Eight patients with pituitary tumors were operated via the transseptal transsphenoidal approach from April to November 2004 at Hospital Ipoh. Seven patients presented with visual disturbances while three also had endocrine abnormalities. The post-operative follow-up period was between six months to a year. There was no mortality in this series. There were no complications related to the approach i.e. nasal or septal related. All patients with visual impairment showed improvement. Only one patient had hormonal irregularities. The endoscopic assisted transseptal approach to the sphenoid sinus for pituitary surgery was found to be easy and without sinonasal or labial complications often found with the sublabial approach.
    Matched MeSH terms: Pituitary Neoplasms/surgery
  3. Tang IP, Chai CK, Kumar G, Prepageran N, Waran V
    Br J Neurosurg, 2014 Jun;28(3):390-2.
    PMID: 23875880 DOI: 10.3109/02688697.2013.817535
    Isolated intrasellar pituitary mucocele following transsphenoidal sinus surgery is extremely rare. The clinical features resemble a pituitary tumor, therefore careful radiological interpretation is crucial to reach the correct diagnosis. We report a case of intrasellar mucocele who had transsphenoidal sinus surgery performed 15 years prior.
    Matched MeSH terms: Pituitary Neoplasms/surgery
  4. Sand MS, Gendeh BS, Husain S
    Med J Malaysia, 2011 Dec;66(5):443-6.
    PMID: 22390098 MyJurnal
    The purpose of this retrospective joint rhino-neurosurgical study from January 1998 until September 2009 is to document the demographic data, clinical presentations, radiological findings, approaches and incidence of residual tumour. Forty-seven patients with pituitary adenoma underwent trans-sphenoidal hypophysectomy of which 25 patients with complete medical and radiological data were included in the study. The medical and radiological data were analyzed. There were 12 males and 13 females with age ranging from 17 to 76 years old (mean 49.2). Fourteen of the patients were Chinese, eight Malays and three Indians. Twelve of the patients had functioning tumour of which five each presented with acromegaly and Cushing disease respectively and two with amenorrhoea. The rest of 13 patients had non functioning tumour presenting with visual disturbances. Sixteen of the patients had pituitary macroadenomas and the rest 9 microadenomas. Eighteen patients had undergone transcollumellar trans-sphenoidal hypophysectomy and the rest 7 patients had undergone transnasal transsphenoidal hypophysectomy. About 68.8% of pituitary macroadenomas had residual tumour, compared to only 22.2% of patient with pituitary microadenomas. Radiologically, about 45.5% of residual macroadenoma had suprasellar extension and the majority had spread to suprasellar cistern and carvenous sinus (54.5%). About 16.6% of patients had undergone post operative radiotherapy. In conclusion, this study showed that patient with pituitary macroadenomas had higher incidence of residual tumour compared to pituitary microadenomas.
    Matched MeSH terms: Pituitary Neoplasms/surgery*
  5. Aboud SK, Yunus MR, Gendeh BS
    Otolaryngol Head Neck Surg, 2011 Jun;144(6):1005-6.
    PMID: 21493376 DOI: 10.1177/0194599810390899
    Matched MeSH terms: Pituitary Neoplasms/surgery*
  6. Gendeh BS, Sakina MS, Selladurai BM, Jegan T, Misiran K
    Med J Malaysia, 2006 Aug;61(3):349-54.
    PMID: 17240588
    A retrospective review was performed on 11 patients who had undergone the transcolumellar transsphenoidal hypophysectomy in our center. There were eight females and three males with age ranging from 17 to 72 years (mean 50 years). Ten patients had pituitary macroadenomas and one had suprasellar cyst. The mean follow up duration for these 11 patients post surgery was 7.2 months. Complications included two cerebrospinal leaks, one postoperative sphenopalatine bleed, one septal perforation and one patient developed numbness of the tip of the nose. We found that this approach is a preferred alternative technique especially in smaller Oriental noses with lower complication rate and better aesthetic result.
    Matched MeSH terms: Pituitary Neoplasms/surgery*
  7. Gendeh BS, Doi M, Selladurai BM, Khalid BA, Jegan T, Misiran K
    Med J Malaysia, 2006 Aug;61(3):343-8.
    PMID: 17240587
    Surgery for pituitary tumours at our institution was performed by rhinosurgical route by combined procedure by otolaryngologist and neurosurgeons. A retrospective review of case records of patients who had endonasal endoscopic transphenoidal approach for pituitary tumours from September 1998 to December 2004 was performed. A total of 81 trans-sphenoidal surgeries were performed during this study period. Only 68 case records with adequate information were available for review, 56 patients were included in the study and 12 were excluded. There were 24 males (42%) and 32 females (58%). The ethnic distribution, were 29 Malays, 24 Chinese, 2 Indian and 1 others. The age ranged from 16 years to 76 years, with a mean of 46 years. The majority of our patients presented with visual symptoms (38), headache (28), menstrual cycle disturbance or impotence (14) and acromegalic features (16). Forty patients had macroadenoma (71%) and 16 had microadenomas (29%). Thirty-six patients out of 40 macro-adenomas had suprasellar extensions (90%). Only eleven patients had lumbar drain inserted prior to commencement of the surgery and the majority of these were macroadenomas. The common complications encountered were diabetes insipidus (4), cerebrospinal fluid leak (2), meningitis (3), epistaxis (2), septal perforation (2), intercavernous sinus haemorrhage (3) and anterior pituitary insufficiency (2). Our study reveals that endonasal trans-sphenoidal approach is a safe and effective method of management of pituitary adenomas.
    Matched MeSH terms: Pituitary Neoplasms/surgery
  8. Said H, Cheah F, Mohamed AS, Hadi AR
    Med J Malaysia, 1993 Jun;48(2):222-4.
    PMID: 8350800
    The transseptal transsphenoidal hypophysectomy has become a relatively frequent procedure in recent years. We performed 20 such procedures between January 1984 and December 1987 for various pituitary disorders. Significant complications such as CSF rhinorrhea, meningitis, diabetes insipidus, haemorrhage and septal perforation are discussed. The mortality rate for the series was 5%. In analysing the data, we feel that this technique of hypophysectomy is a safe procedure.
    Matched MeSH terms: Pituitary Neoplasms/surgery*
  9. Waran V, Tang IP, Karuppiah R, Abd Kadir KA, Chandran H, Muthusamy KA, et al.
    Br J Neurosurg, 2013 Dec;27(6):742-6.
    PMID: 23647078 DOI: 10.3109/02688697.2013.791667
    Abstract The endoscopic transnasal, transsphenoidal surgical technique for pituitary tumour excision has generally been regarded as a less invasive technique, ranging from single nostril to dual nostril techniques. We propose a single nostril technique using a modified nasal speculum as a preferred technique. We initially reviewed 25 patients who underwent pituitary tumour excision, via endoscopic transnasal transsphenoidal surgery, using this new modified speculum-guided single nostril technique. The results show shorter operation time with reduced intra- and post-operative nasal soft tissue injuries and complications.
    Matched MeSH terms: Pituitary Neoplasms/surgery
  10. Norlela S, Azmi KN, Khalid BA
    Singapore Med J, 2006 Jan;47(1):75-6.
    PMID: 16397727
    A 53-year-old acromegalic woman had cerebrospinal fluid rhinorrhoea following transphenoidal surgery for a pituitary microadenoma. A continuous lumbar spinal fluid drainage catheter was inserted and on the sixth postoperative day, she developed hyponatremia with features of syndrome of inappropriate antidiuretic hormone (SIADH) requiring hypertonic saline administration. Over-drainage is potentially hazardous and close biochemical monitoring is required. To our knowledge, this is the first reported case of SIADH caused by continuous lumbar drainage in an adult.
    Matched MeSH terms: Pituitary Neoplasms/surgery
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