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Evolving trends in stem cell therapy: an emerging and promising approach against various diseases

Abusalah MAH, Priyanka, Abd Rahman ENSE, Choudhary OP

Int J Surg, 2024 Nov 01;110(11):6862-6868.
PMID: 39699861 DOI: 10.1097/JS9.0000000000001948
A prognostic insight of the mRNA vaccine against antibiotic-resistant bacteria

Abusalah MAH, Choudhary P, Bargui H, Ahmed N, Abusalah MAH, Choudhary OP

Ann Med Surg (Lond), 2024 Jul;86(7):3801-3805.
PMID: 38989193 DOI: 10.1097/MS9.0000000000001970
The Epigenesis of Salivary Glands Carcinoma: From Field Cancerization to Carcinogenesis

Mat Lazim N, Yousaf A, Abusalah MAH, Sulong S, Mohd Ismail ZI, Mohamud R, et al.

Cancers (Basel), 2023 Mar 31;15(7).
PMID: 37046772 DOI: 10.3390/cancers15072111

Salivary gland carcinomas (SGCs) are a diverse collection of malignant tumors with marked differences in biological activity, clinical presentation and microscopic appearance. Although the etiology is varied, secondary radiation, oncogenic viruses as well as chromosomal rearrangements have all been linked to the formation of SGCs. Epigenetic modifications may also contribute to the genesis and progression of SGCs. Epigenetic modifications are any heritable changes in gene expression that are not caused by changes in DNA sequence. It is now widely accepted that epigenetics plays an important role in SGCs development. A basic epigenetic process that has been linked to a variety of pathological as well as physiological conditions including cancer formation, is DNA methylation. Transcriptional repression is caused by CpG islands hypermethylation at gene promoters, whereas hypomethylation causes overexpression of a gene. Epigenetic changes in SGCs have been identified, and they have been linked to the genesis, progression as well as prognosis of these neoplasms. Thus, we conduct a thorough evaluation of the currently known evidence on the involvement of epigenetic processes in SGCs.
Fulltext The association between breast cancer and consumption of dairy products: a systematic review

Arafat HM, Omar J, Shafii N, Naser IA, Al Laham NA, Muhamad R, et al.

Ann Med, 2023 Dec;55(1):2198256.
PMID: 37078247 DOI: 10.1080/07853890.2023.2198256

BACKGROUND: Among the world, the most frequently discovered and fatal cancer in women is breast cancer (BC). From the perspective of public health, estimating the BC risk linked to dairy intake may aid in comprehensive management. In epidemiological research data on the association between eating dairy foods and the risk of BC are conflicting. Therefore, we sought to assess the link between dairy food consumption and the development of BC.
MAIN TEXT: To summarize and quantify the most recent findings on consuming milk or other dairy foods and the development of BC, we performed a systematic literature review. We checked through several databases for relevant publications published in English up to January 2022. Of the 82 articles identified, only 18 met the inclusion criteria and were analyzed. Nine Prospective, seven Retrospective and two Cross-Sectional studies were finally identified.
CONCLUSIONS: Overall, dairy consumption was inversely associated with the risk of developing breast cancer. Future studies will help elucidate the role of dairy products in human health, and their use within a balanced diet should be considered.KEY MESSAGESThe effect of different types of dairy products, and possible dose-response relationships on BC risk remains unknown.Estimating BC risk associated with dairy consumption may help to take the decision-making of physicians and public health policy in developing preventive strategies to reduce its occurrence.This systematic review was conducted to assess dairy consumption and BC risk.Overall, inverse associations were found when looking at dairy consumption and BC risk.