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MyMedR (Malaysian Medical Repository) is an open access collection of Malaysian health and biomedical research. The materials are imported from PubMed and MyJurnal. We gratefully acknowledge the permission to reuse the materials from the National Library of Medicine of the United States and the Malaysian Citation Centre. This project is funded by Academy of Family Physicians of Malaysia. The project team members are: CL Teng, CJ Ng, EM Khoo, Mastura Ismail, Abrizah Abdullah, TK Chiew, Thanaletchumi Dharmalingam.

Please note that some citations are non-Malaysian publications. Common reasons are: (1) One or more authors had a Malaysian affiliation; (2) The article abstract mentioned Malaysia; (3) The study subjects included Malay ethnic group.

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  1. Kumaran Gengatharan, Azali Rahmat
    MyJurnal
    Kajian ini bertujuan untuk membangunkan modul pentaksiran Pendidikan Kesihatan dalam Pentaksiran Bilik Darjah (PBD) untuk guru tahap Satu. Objektif kajian adalah untuk mengenal pasti keperluan modul pentaksiran Pendidikan Kesihatan dalam pentaksiran bilik darjah dalam pengajaran guru tahap satu. Reka bentuk yang digunakan dalam kajian ini adalah reka bentuk dan pembangunan (RBP) yang mempunyai tiga fasa. Fasa pertama ialah analisis keperluan, fasa kedua ialah reka bentuk dan pembangunan dan manakala fasa ketiga ialah fasa pelaksanaan dan penilaian. Instrumen yang digunakan dalam kajian ini ialah soal selidik untuk mengetahui keperluan bahan pentaksiran iaitu modul pentaksiran untuk guru Pendidikan Kesihatan yang mengajar murid tahap satu dalam pelaksanaan PBD. Dapatan kajian menunjukkan memang terdapat keperluan untuk membangunkan modul pentaksiran bagi subjek Pendidikan Kesihatan untuk guru tahap satu dalam pelaksanaan PBD.
  2. Nabilah Yaakub, Norsaleha Mohd Ariffin, Nelfianty Mohd Rasyid
    MyJurnal
    Kajian ini bertujuan untuk mengkaji hubungan antara orientasi matlamat dan keseronokan dalam kalangan atlet hoki UPSI. Kajian tinjauan ini dijalankan dalam kalangan 30 orang altet yang mewakili UPSI dalam kejohanan hoki peringkat Universiti (lelaki, n=17; perempuan, n=13). Instrumen soal selidik Task and Ego Orientation Sport Questionnaire (TEOSQ) dan Physical Activity Enjoyment Scale (PACES) digunakan untuk mengukur orientasi matlamat dan tahap keseronokan. Analisis deskriptif min dan sisihan piawai; analisis inferens Ujian-t sampel tidak bersandar serta korelasi digunakan untuk mengenalpasti orientasi matlamat dan tahap keseronokan atlet serta perkaitan antara kedua-duanya. Dapatan kajian menunjukkan atlet hoki UPSI lebih berorientasikan tugasan berbanding ego dan mempunyai tahap keseronokan yang sederhana. Hasil keputusan inferens korelasi turut menunjukkan terdapat perkaitan yang signifikan (p = 0.001, p
  3. Nik Nabil Safwan Nik Anuay, Tajul Arifin Muhamad
    MyJurnal
    Kajian ini bertujuan untuk mengkaji tiga tujuan utama iaitu: (1) mengenal pasti tahap tret personaliti di kalangan pegawai sukan di UKM; (2) untuk mengenal pasti tahap prestasi kerja di kalangan pegawai sukan di UKM; (3) untuk mengkaji hubungan antara tret personaliti dan prestasi kerja di kalangan pegawai sukan di UKM. 44 item Questionnaire Inventori Besar Lima (BFI) diadaptasi daripada John dan Srivastava (1999) yang mempunyai lima dimensi, iaitu Ekstraversi, Kesedaran, Keterbukaan fikiran, Kesetujuan dan Neurotisme. Prestasi kerja diukur dengan menggunakan markah daripada Sistem Penilaian Prestasi (SPPP). Soal selidik ini melibatkan responden daripada kalangan pegawai sukan (N = 36) di UKM. Hasilnya menunjukkan bahawa min tertinggi bagi tret personaliti adalah Keterbukaan fikiran dengan nilai min (M = 3.70) dan tahap prestasi kerja adalah sangat tinggi (M = 92.98). Di samping itu, hasil analisis korelasi menunjukkan terdapat hubungan yang signifikan antara tret personaliti dan prestasi kerja di kalangan pegawai sukan di UKM (sig = 0.010, p < 0.05). Kesimpulannya, tret personaliti iaitu keterbukaan fikiran dalam kalangan pegawai sukan amat penting dalam membentuk pekerja agar lebih meningkatkan prestasi dari semasa ke semasa.
  4. Norsaleha Mohd Ariffin, Muhamusyarrifa Hashim, Jeffrey Low Fook Lee
    MyJurnal
  5. M. Adli Mohd Sidi, Muhammad Syakir Sulaiman, Mohd Salihin Hafizi Mohd Fauzi, Julia Mazlan
    MyJurnal
    Kajian ini bertujuan untuk mengenal pasti dan membandingkan tahap kesedaran dan tingkah laku risiko yang "altruistik".antara jantina selain meninjau hubungan antara keduanya dalam kegiatan rekreasi dalam Program Pembangunan Masyarakat Guru (BIG). Satu set soalan yang ditanyakan telah digunakan berbanding 81 pelajar tahun akhir Fakulti Pendidikan, KUIS di Raub, Pahang. Persoalan penyelidikan terdiri daripada dua perubahan, iaitu kesadaran terhadap risiko dan tingkah laku keselamatan. Hasil kajian menunjukkan kesedaran yang tinggi tentang risiko semasa aktiviti rekreasi. Analisis ujian T menunjukkan bahawa tidak terdapat perbezaan yang signifikan dalam kesedaran terhadap risiko dan kelakuan keselamatan antara wanita. Analisis korelasi Pearson menunjukkan bahawa terdapat hubungan positif yang signifikan antara kesedaran risiko (peraturan keselamatan) dan tingkah laku keselamatan "altruistic". Implikasi kajian ini ialah rekreasi dan pentadbir universiti perlu mengambil kira pelbagai jenis risiko dalam merekabentuk aktiviti rekreasi luar. Tahap kesadaran risiko yang tinggi dapat membantu pelajar dengan tingkah laku yang baik dalam aktiviti rekreasi luar yang mereka berminat.
  6. Wan Firdaus Wan Chik, NUR KHAIRUNISA ABU TALIP, Cliston Siricord
    MyJurnal
    Futsal is a high intensity team sport game that demands a high physical, technical and tactical ability. The elements of kicking and jumping demands a strong lower body, in which quadriceps act as the primary muscles, whereas the hamstring act as the balancer of the knee joint. The aim of the study was to investigate the effect of eccentric strength training and static stretch on hamstring flexibility among futsal players. 10 recreative male futsal players (n=10) recruited from Universiti Teknologi MARA (UiTM) Samarahan for the study. Subjects were randomly assigned into two groups comprised of eccentric strength training group and static stretching group. Eccentric strength training performed the Nordic hamstring exercise while, static stretch group performed static stretching exercise. All participants went through a 4 weeks program respectively to the set group, with 3 sessions each week. Sit and reach flexibility test was measured. Both groups showed a significant difference between pre and post-test, F = 22.478, p = .001 (p
  7. Yenchitsomanus PT, Sawasdee N, Paemanee A, Keskanokwong T, Vasuvattakul S, Bejrachandra S, et al.
    J. Hum. Genet., 2003;48(9):451-456.
    PMID: 12938018 DOI: 10.1007/s10038-003-0059-6
    We have previously demonstrated that compound heterozygous (SAO/G701D) and homozygous (G701D/G701D) mutations of the anion exchanger 1 (AE1) gene, encoding erythroid and kidney AE1 proteins, cause autosomal recessive distal renal tubular acidosis (AR dRTA) in Thai patients. It is thus of interest to examine the prevalence of these mutations in the Thai population. The SAO and G701D mutations were examined in 844 individuals from north, northeast, central, and south Thailand. Other reported mutations including R602H, DeltaV850, and A858D were also examined in some groups of subjects. The SAO mutation was common in the southern Thai population; its heterozygote frequency was 7/206 and estimated allele frequency 1.70%. However, this mutation was not observed in populations of three other regions of Thailand. In contrast, the G701D mutation was not found in the southern population but was observed in the northern, northeastern, and central populations, with heterozygote frequencies of 1/216, 3/205, and 1/217, and estimated allele frequencies of 0.23%, 0.73%, and 0.23%, respectively. The higher allele frequency of the G701D mutation in the northeastern Thai population corresponds to our previous finding that all Thai patients with AR dRTA attributable to homozygous G701D mutation originate from this population. This suggests that the G701D allele that is observed in this region might arise in northeastern Thailand. The presence of patients with compound heterozygous SAO/G701D in southern Thailand and Malaysia and their apparently absence in northeastern Thailand indicate that the G701D allele may have migrated to the southern peninsular region where SAO is common, resulting in pathogenic allelic interaction.
    MeSH terms: Acidosis, Renal Tubular/genetics*; Acidosis, Renal Tubular/epidemiology; Anion Exchange Protein 1, Erythrocyte/genetics*; DNA Mutational Analysis; Gene Frequency; Genes, Recessive/genetics; Genetic Testing/methods; Heterozygote Detection; Homozygote; Humans; Malaysia/epidemiology; Mutation/genetics*; Thailand/epidemiology; Polymerase Chain Reaction; DNA Primers/chemistry
  8. Siti Nur Atika Mohd Sanif, Justin Vijay Gnanou, Brinnell Annette Caszo, Harbindarjeet Singh
    MyJurnal
    Leptin affects insulin secretion and action through either a central or peripheral mechanism. It increases glucose metabolism and energy expenditure. Though overweight and obese individuals have been reported to have high circulating leptin levels, these effects of leptin are not evident. Exercise, on the other hand, has been found to increase glucose uptake in these individuals. This study examined the effect of chronic leptin treatment and exercise on body weight, glucose homeostasis and insulin sensitivity in Sprague-Dawley rats. Eight-week old rats were treated with either intraperitoneal injection of normal saline (Control; n=8), or leptin (60 μg/kg body weight/day; Leptin; n=8), or leptin and exercise (60 μg/kg body weight/day plus running on a treadmill every other day for 30 minutes at a speed of 30 m/min with 10° inclinations; Leptin-exercise; n=8) or exercise only (running every other day for 30 minutes at a speed of 30 m/min with 10° inclinations on a treadmill; Exercise; n=8) for six weeks. Following six weeks of treatment, glucose challenge was performed by intravenous infusion of 100 mg/ml of glucose for 5 minutes. During the protocol, blood was drawn at 0, 5, 10, 15, 20, 25 and 30-min for blood glucose, serum glucose, and serum insulin levels determination. Data were analyzed using One Way ANOVA with post-hoc analysis and expressed as mean ± standard error of mean (SEM). Despite no different in body weight between the groups, leptin group had a slightly higher trend of mean body weight compared to other groups. Glucose clearance was delayed in the leptin group. This delay in glucose clearance might be associated with lower insulin level and action in leptin group. More importantly, exercise reversed the leptin effects by promoting glucose clearance despite a significantly lower insulin peak, indicating increase in insulin sensitivity. In conclusion, six weeks of daily leptin administration resulted in delayed glucose clearance, but concurrent exercise however prevented these effects of leptin by promoting glucose clearance and increasing insulin sensitivity.
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