Laser cutting is a non-contact machining employed for producing small, intricate shapes. The acrylic materials are widely used in many applications. The parametric and heat affected zone study of acrylic materials by using CO2 laser machining is attempted in this research to evaluate the process variables, laser scanning speed, current, and nozzle-work material gap.•Research result indicate that the higher the current and the higher the cutting speed, result in higher the material removal rate•Other parameter such as current and nozzle, work material gap are also significant impact on the cutting process of the acrylic material.•In addition, heat affect zone increase with laser scanning speed.