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  1. Fulltext Lung Mass With Crazy-Paving: An Unusual Initial Presentation of Acute Myeloid Leukaemia
    Woo FB, Tan HL, Maria Dass RD, Sivandan S
    Respirol Case Rep, 2025 Feb;13(2):e70128.
    PMID: 39975980 DOI: 10.1002/rcr2.70128
    Acute myeloid leukaemia is known to present non-specifically and more commonly with B symptoms. We report an interesting presentation of acute myeloid leukaemia as a lung mass which initially raised clinical suspicion of primary lung cancer. A gentleman in his 50s who is an active smoker presented with chronic cough, lethargy, and giddiness for 2 months. Physical examination revealed pallor, cervical lymphadenopathy, and bronchial breathing over the right middle zone on auscultation. CT thorax showed a spiculated solid mass with a crazy-paving pattern, suggestive of lung cancer. However, blood workup showed pancytopenia with a full blood picture showing 60% blast cells. Subsequent bone marrow examination confirmed the diagnosis of AML. The patient received 2-weekly venetoclax-based chemotherapy. Serial follow-up CT showed resolution of lung changes and the patient remained in remission.
  2. Fulltext Clinical role of intrarenal venous flow patterns in decompensated heart failure with worsening renal function
    Poh KW, Ngan CH, Tan SN, Burhan AA, Wong JY, Er CK, et al.
    Ultrasound, 2023 May;31(2):119-125.
    PMID: 37144225 DOI: 10.1177/1742271X221124467
    INTRODUCTION: The clinical implication of intrarenal venous flow patterns in decompensated heart failure with worsening renal function is unknown. We aimed to study the relationship between intrarenal venous flow patterns, inferior vena cava volume status, caval index, clinical degree of congestion and the renal outcome in patients with decompensated heart failure and worsening renal function. Secondary objectives were to study the combined endpoint of readmission and mortality rate within 30 days (after the last scan) among intrarenal venous flow patterns and the effect of congestion status on the renal outcome.

    METHODS: Twenty-three patients admitted for decompensated heart failure (ejection fraction ⩽40%) with worsening renal function (absolute increase in serum creatinine of 26.5 µmol/L or ⩾1.5-fold increment from baseline) were enrolled in this study. A total of 64 scans were performed. Patients were visited on day 0, 2, 4 and 7 (or earlier if discharged). Patients were called 30 days after discharge to evaluate readmission or mortality. Intrarenal venous flow patterns were ranked from continuous, interrupted, biphasic, to monophasic. Clinical congestion was scored from 0 to 7.

    RESULTS: Intrarenal venous flow patterns had statistically significant positive correlations with inferior vena cava volume status (Spearman's ρ, 0.51; p 

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