MyMedR

A young lady with thalamic stroke mimicking acute Miller Fisher syndrome

Hasan S, Stanslas J, Hin LP, Basri HB

Neurosciences (Riyadh), 2012 Oct;17(4):380-1.

Brain magnetic resonance image segmentation using novel improvement for expectation maximizing

Balafar MA, Ramli AR, Mashohor S

Neurosciences (Riyadh), 2011 Jul;16(3):242-7.

To improve the quality of expectation maximizing (EM) for brain image segmentation, and to evaluate the accuracy of segmentation results.

Fulltext Coexistence of CACNA1A, ATP1A2, and KCNN3 gene mutation in migraine patients with human platelet polymorphism

Bhaskar S, Abdullah JM, Ghazali MM

Neurosciences (Riyadh), 2008 Oct;13(4):356-8.

PMID: 21063360

OBJECTIVE: To look for any possible coexistence of CACNA1A, ATP1A2, and KCNN3 gene mutations in migraine patients who had human platelet HPA-1a/1b polymorphism, which is also known as PlA1/A2 polymorphism.
METHODS: The study was carried out at the Neurology Clinic, Hospital University Sains Malaysia, Kelantan, Malaysia between April 2004 and March 2005. The DNA from 4 patients who had migraine with the HPA1a/1b polymorphism were analyzed by polymerase chain reaction using the allele specific oligonucleotide technique to detect the presence of CACNA1A, ATP1A2, and KCNN3 genotypes.
RESULTS: We found that the CACNA1A gene mutation alone was present in only one patient who presented with classical migraine with aura. The gene mutations on ATP1A2 and KCNN3 were seen in none of our 4 cases with migraine.
CONCLUSION: There is no coexistence between the platelet HPA-1a/1b polymorphism and the ATP1A2 and KCNN3 gene mutations, though one classical migraine patient with HPA-1a/1b polymorphism had the CACNA1A gene mutation. Larger studies are warranted to confirm these findings.
Study site: Neurology Clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia

Human memory retention and recall processes. A review of EEG and fMRI studies

Amin H, Malik AS

Neurosciences (Riyadh), 2013 Oct;18(4):330-44.

PMID: 24141456

Human memory is an important concept in cognitive psychology and neuroscience. Our brain is actively engaged in functions of learning and memorization. Generally, human memory has been classified into 2 groups: short-term/working memory, and long-term memory. Using different memory paradigms and brain mapping techniques, psychologists and neuroscientists have identified 3 memory processes: encoding, retention, and recall. These processes have been studied using EEG and functional MRI (fMRI) in cognitive and neuroscience research. This study reviews previous research reported for human memory processes, particularly brain behavior in memory retention and recall processes with the use of EEG and fMRI. We discuss issues and challenges related to memory research with EEG and fMRI techniques.

Fulltext Patient-reported side effects of lamotrigine during routine clinic visits

Daud NA, Ab-Rahman A

Neurosciences (Riyadh), 2012 Jul;17(3):269-70.

PMID: 22772938

Fulltext Platelet alloantigen polymorphism and migraine headaches

Bhaskar S, Abdullah JM

Neurosciences (Riyadh), 2013 Apr;18(2):185-6.

PMID: 23545624

Postural sway changes during static standing with concurrent task in children with traumatic brain injury

Abdul Rahman RA, Hanapiah FA, Nikmat AW, Ismail NA, Manaf H

Neurosciences (Riyadh), 2019 01;24(1):29-35.

PMID: 30842397 DOI: 10.17712/nsj.2019.1.20180195

OBJECTIVE: To investigate the effects of concurrent tasks (motor and cognitive) on postural control performance in children with traumatic brain injury (TBI) compared to typically developing (TD) control subjects.

METHODS: Sixteen children with TBI (aged 11.63+/-1.89 years) and 22 TD controls (aged 11.41+/-2.24 years) participated in this case-control study. This study was conducted between May 2016 and March 2017. Each child performed static standing under 3 different conditions: single, concurrent motor, and concurrent cognitive task. Postural control performance measure includes sway area, anterior-posterior (AP) sway velocity, medio-lateral (ML) sway velocity, AP sway distance and ML sway distance as measured using the APDM Mobility Lab (Oregon, Portland). A repeated-measure analysis of variance was used to analyse the data.

RESULTS: We found that children with TBI showed significantly more deterioration in postural control performance than TD children (p<0.05). Both concurrent tasks (motor and cognitive) significantly decreased postural control performance in both groups with more pronounced changes in children with TBI than that of the TD controls.

CONCLUSION: The results demonstrated that, performing concurrent tasks (motor and cognitive) during upright standing resulted in deterioration of postural control performance. The existence of cognitive and balance impairment in children with TBI will possibly cause concurrent tasks to be more complex and demands greater attention compared to single task.

Displaying all 7 publications