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Osseous choristoma of the tongue

Wei Cheong Ngeow, Chin Boon Lian, Shanmahasuntharam P

J Nihon Univ Sch Dent, 1996 Mar;38(1):49-51.
PMID: 8648411

The term "choristoma" is used to describe a mass of histologically normal tissue presenting in an aberrant site. A rare case of osseous choristoma of the tongue is presented and the literature is briefly reviewed.

Matched MeSH terms: Ossification, Heterotopic/pathology*
Heterotopic ossification in skeletal muscle metastasis from colonic adenocarcinoma--a case report

Naik VR, Jaafar H, Mutum SS

Malays J Pathol, 2005 Dec;27(2):119-21.
PMID: 17191396

Colonic adenocarcinoma metastasising to the skeletal muscle is rare. A-56-yr-old Malay man was diagnosed to have adenocarcinoma of the right colon [Dukes B] for which a right hemicolectomy was performed, followed by radiotherapy and chemotherapy. Five years later the patient presented with a mass in the rectus abdominis muscle. The serum carcinoembryonic antigen was 71 ng/Ml. The mass was resected. Gross and microscopical examination showed multiple deposits of mucin-secreting adenocarcinoma with prominent heterotopic ossification in the stroma. The exact pathogenesis and significance of heterotopic ossification is not clear, but bone morphogenetic proteins may play an important role.

Matched MeSH terms: Ossification, Heterotopic/pathology*
Fulltext Anatomical and Radiological Findings of Abnormal Calcified Structures within and around the Foramen Transversarium and Its Clinical Implications

Chakravarthi KK, Nelluri V, Reghunadhan D, Sugavasi R

Ann Afr Med, 2024 Oct 01;23(4):641-648.
PMID: 39138967 DOI: 10.4103/aam.aam_73_24

BACKGROUND: The foramen transversarium is a vital anatomical structure found in the cervical vertebrae of the spine. Typically, it serves as a passageway for important neurovascular structures, including the vertebral artery and vein, as well as the vertebral nerve. However, abnormal calcification or ossification of soft tissues in and around this area can lead to various clinical implications. Understanding the presence and implications of abnormal ossified structures in and around the foramen transversarium is crucial for clinicians involved in the diagnosis and management of cervical spine disorders.
AIMS: Accordingly, this present study was designed to evaluate the abnormal ossified structures anatomically and radiologically within and around the foramen transversarium.
MATERIALS AND METHODS: This study was conducted on 182 (26 sets of cervical vertebrae) dried human cervical vertebrae obtained from the respective departments of anatomy and on 190 (95 males and 95 females) adult patients who visited the radiology department for neck-related problems such as stiff neck, neck/shoulder pain, dizziness, vertigo, imbalance, visual disturbances, and cognitive impairment.
RESULTS: Among 182 examined cervical vertebrae, unilateral complete accessory foramen transversarium was found in 23 vertebrae (12.63%), bilateral complete in 19 (10.44%), bilateral incomplete in 6 (3.29%), unilateral complete double in 4 (2.19%), and unilateral complete absence of foramen transversarium in 3 (1.64%). Stenosis due to aberrant osteophytes was noted in 9 vertebrae (4.9%). Out of 190 patients, three males presented with cervical kyphosis, severe spinal canal stenosis, and spinal cord compression due to ossification of the posterior longitudinal ligament and osteophyte complexes at C3-C6, with the most significant compression at C5-C6.
CONCLUSION: A thorough understanding of abnormal ossifications in and around the foramen transversarium is crucial for the management of cervical spine disorders; imaging modalities such as X-ray, computed tomography, and magnetic resonance imaging are crucial for recognizing and intervening in these cases, which is essential to prevent adverse neurological outcomes associated with vertebral artery involvement.

Matched MeSH terms: Ossification, Heterotopic/pathology
Ossified lumbar pseudomeningocele: imaging findings

Al-Edrus SA, Mohamed Mukari SA, Ganesan D, Ramli N

Spine J, 2011 Aug;11(8):796-7.
PMID: 21724472 DOI: 10.1016/j.spinee.2011.05.013
Matched MeSH terms: Ossification, Heterotopic/pathology*
Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases

Zain RB, Fei YJ

Oral Surg. Oral Med. Oral Pathol., 1990 Oct;70(4):466-70.
PMID: 2120653

Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, 79.5% were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7%) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.

Matched MeSH terms: Ossification, Heterotopic/pathology
Ossification of caroticoclinoid ligament and its clinical importance in skull-based surgery

Das S, Suri R, Kapur V

Sao Paulo Med J, 2007 Nov 01;125(6):351-3.
PMID: 18317606

CONTEXT: The medial end of the posterior border of the sphenoid bone presents the anterior clinoid process (ACP), which is usually accessed for operations involving the clinoid space and the cavernous sinus. The ACP is often connected to the middle clinoid process (MCP) by a ligament known as the caroticoclinoid ligament (CCL), which may be ossified, forming the caroticoclinoid foramen (CCF). Variations in the ACP other than ossification are rare. The ossified CCL may have compressive effects on the internal carotid artery. Thus, anatomical and radiological knowledge of the ACP and the clinoid space is also important when operating on the internal carotid artery. Excision of the ACP may be required for many skull-based surgical procedures, and the presence of any anomalies such as ossified CCL may pose a problem for neurosurgeons.
CASE REPORT: We observed the presence of ossified CCL in a skull bone. A detailed radiological study of the CCL and the CCF was conducted. Morphometric measurements were recorded and photographs were taken. The ACP was connected to the MCP and was converted into a CCF. Considering the fact that standard anatomy textbooks do not provide morphological descriptions and radiological evaluations of the CCL, the present study may be important for neurosurgeons operating in the region of the ACP.

Matched MeSH terms: Ossification, Heterotopic/pathology*
Radiographic and computed tomographic assessment of the development of the antebrachia and elbow joints in Labrador Retrievers with and without medial coronoid disease

Lau SF, Hazewinkel HA, Voorhout G

Vet Comp Orthop Traumatol, 2015;28(3):186-92.
PMID: 25804656 DOI: 10.3415/VCOT-14-09-0144

To compare the development, monitored by radiography and computed tomography, of the antebrachia and elbow joints in seven Labrador Retrievers with healthy elbow joints and in seven Labrador Retrievers that developed medial coronoid disease (MCD), in order to determine whether disturbances in the development of the antebrachia and elbow joints, between the age of six and 17 weeks may lead to medial coronoid disease.

Matched MeSH terms: Ossification, Heterotopic/pathology