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  1. Fulltext Recent updates on metabolite composition and medicinal benefits of mangosteen plant
    Aizat WM, Jamil IN, Ahmad-Hashim FH, Noor NM
    PeerJ, 2019;7:e6324.
    PMID: 30755827 DOI: 10.7717/peerj.6324
    BACKGROUND: Mangosteen (Garcinia mangostana L.) fruit has a unique sweet-sour taste and is rich in beneficial compounds such as xanthones. Mangosteen originally been used in various folk medicines to treat diarrhea, wounds, and fever. More recently, it had been used as a major component in health supplement products for weight loss and for promoting general health. This is perhaps due to its known medicinal benefits, including as anti-oxidant and anti-inflammation. Interestingly, publications related to mangosteen have surged in recent years, suggesting its popularity and usefulness in research laboratories. However, there are still no updated reviews (up to 2018) in this booming research area, particularly on its metabolite composition and medicinal benefits.

    METHOD: In this review, we have covered recent articles within the years of 2016 to 2018 which focus on several aspects including the latest findings on the compound composition of mangosteen fruit as well as its medicinal usages.

    RESULT: Mangosteen has been vastly used in medicinal areas including in anti-cancer, anti-microbial, and anti-diabetes treatments. Furthermore, we have also described the benefits of mangosteen extract in protecting various human organs such as liver, skin, joint, eye, neuron, bowel, and cardiovascular tissues against disorders and diseases.

    CONCLUSION: All in all, this review describes the numerous manipulations of mangosteen extracted compounds in medicinal areas and highlights the current trend of its research. This will be important for future directed research and may allow researchers to tackle the next big challenge in mangosteen study: drug development and human applications.

  2. Fulltext Valorization of mangosteen, "The Queen of Fruits," and new advances in postharvest and in food and engineering applications: A review
    Aizat WM, Ahmad-Hashim FH, Syed Jaafar SN
    J Adv Res, 2019 Nov;20:61-70.
    PMID: 31210985 DOI: 10.1016/j.jare.2019.05.005
    One of the most prolific plants utilized in various applications is mangosteen (Garcinia mangostana L.). Rich in potent bioactive compounds, such as xanthones, mangosteen is known to possess pharmacologically important anti-inflammatory and anti-tumor properties. However, most previous reviews have only discussed the application of mangosteen in medicinal areas, yet more recent studies have diverged and valorized its usage in other scientific fields. In this review, the utilization of this exotic fruit in postharvest biology (phytohormone roles, metabolite profiling, bioactive compounds, isolation method optimization, chemical contaminant identification, and management of pests and fruit disorders), food science (food products, animal feed supplementation, and food shelf-life determination), and engineering fields (fabric and solar cell dyes, carbon dots, activated carbon, and biomedical advanced materials) is presented in detail. Research papers published from 2016 onward were selected and reviewed to show the recent research trends in these areas. In conclusion, mangosteen has been utilized for various purposes, ranging from usage in industrially important products to applications in advanced technologies and biomedical innovation.
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