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  1. Fulltext Self-Medication Among King Khalid University Students, Saudi Arabia
    Alshahrani SM, Alavudeen SS, Alakhali KM, Al-Worafi YM, Bahamdan AK, Vigneshwaran E
    Risk Manag Healthc Policy, 2019;12:243-249.
    PMID: 31814786 DOI: 10.2147/RMHP.S230257
    Purpose: This study objective was to explore the pattern of self-medications among King Khalid University students, Saudi Arabia.

    Patients and methods: A cross-sectional study was conducted over five months among King Khalid University students, Abha, Saudi Arabia.

    Results: Among all the study participants, nearly 98.7% were practicing self-medication. Headache (75.9%), cough and cold (52.5%), and fever (35.6%) and body pain (24.6%) were the most reported symptoms. Use of painkillers (91.6%) was significantly predominant among the medical students, whereas non-medical students used antibiotics (35.4%).Time saving (64.2%), mild symptom (51.7%) and quick relief (36.9%) were the reasons behind seeking self-medication in this study.

    Conclusion: Self-medications was common in King Khalid University. Educational programs are highly recommended.

  2. Levosimendan: mechanistic insight and its diverse future aspects in cardiac care
    Akhtar MS, Hassan MQ, Siddiqui A, Alavudeen SS, Afzal O, Altamimi ASA, et al.
    Acta Cardiol, 2023 Apr;78(2):170-187.
    PMID: 36222590 DOI: 10.1080/00015385.2022.2115761
    Inotropic agents are generally recommended to use in patients with acute decompensated heart failure (HF) with reduced ejection fraction (HFrEF) concurrent to end-organ dysfunction. However, due to certain pharmacological limitations like developing life threatening arrhythmia and tolerance, cannot be employed as much as needed. Meanwhile, Calcium ion (Ca2+) sensitisers exhibits their inotropic action by increasing the sensitivity of the cardiomyocyte to intracellular Ca2+ ion and have been reported as emerging therapeutic alternative in HF cases. Levosimendan (LEVO) is an inodilator and with its unique pharmacology justifying its use in a wide range of cardiac alterations in HF particularly in undergoing cardiac surgery. It is also reported to be better than classical inotropes in maintaining cardiac mechanical efficacy and reducing congestion in acute HF with hypotension. This review paper was designed to compile various evidence about basic pharmacology and potential clinical aspects of LEVO in cardiac surgery and other HF associated alterations. This will benefit directly to the researcher in initiating research and to fill the gaps in the area of thrust.
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