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  1. Hawley WA, Reiter P, Copeland RS, Pumpuni CB, Craig GB
    Science, 1987 May 29;236(4805):1114-6.
    PMID: 3576225
    North American strains of Aedes albopictus, an Asian mosquito recently introduced into the Western Hemisphere, exhibit photoperiodic sensitivity and cold-hardiness characteristics similar to strains originating from temperate zone Asia. Trade statistics for used tire imports, the most likely mode of introduction, also indicate a north Asian origin. Aedes albopictus, an important vector of dengue and a potential vector of many other arboviral diseases, may therefore have the capability of infesting much of temperate North America.
  2. Ong T, Copeland R, Thiam CN, Cerda Mas G, Marshall L, Sahota O
    Osteoporos Int, 2021 May;32(5):921-926.
    PMID: 33170309 DOI: 10.1007/s00198-020-05710-8
    Integration of a vertebral fracture identification service into a Fracture Liaison Service is possible. Almost one-fifth of computerised tomography scans performed identified an individual with a fracture. This increase in workload needs to be considered by any FLS that wants to utilise such a service.

    INTRODUCTION: This service improvement project aimed to improve detection of incidental vertebral fractures on routine imaging. It embedded a vertebral fracture identification service (Optasia Medical, OM) on routine computerised tomography (CT) scans performed in this hospital as part of its Fracture Liaison Service (FLS).

    METHODS: The service was integrated into the hospital's CT workstream. Scans of patients aged ≥ 50 years for 3 months were prospectively retrieved, alongside their clinical history and the CT report. Fractures were identified via OM's machine learning algorithm and cross-checked by the OM radiologist. Fractures identified were then added as an addendum to the original CT report and the hospital FLS informed. The FLS made recommendations based on an agreed algorithm.

    RESULTS: In total, 4461 patients with CT scans were retrieved over the 3-month period of which 850 patients had vertebra fractures identified (19.1%). Only 49% had the fractures described on hospital radiology report. On average, 61 patients were identified each week with a median of two fractures. Thirty-six percent were identified by the FLS for further action and recommendations were made to either primary care or the community osteoporosis team within 3 months of fracture detection. Of the 64% not identified for further action, almost half was because the CT was part of cancer assessment or treatment. The remaining were due to a combination of only ≤ 2 mild fractures; already known to a bone health specialist; in the terminal stages of any chronic illness; significant dependency for activities of daily living; or a life expectancy of less than 12 months CONCLUSION: It was feasible to integrate a commercial vertebral fracture identification service into the daily working of a FLS. There was a significant increase in workload which needs to be considered by any future FLS planning to incorporate such a service into their clinical practice.

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