MyMedR

Displaying all 6 publications

Abstract:

Sort:

Fulltext Role of cardiac MRI in detecting familial hypertrophic cardiomyopathy: review

Koshy M, Bushra Johari, Mohd Farhan Hamdan, Mohammad Hanafiah

Journal of Clinical and Health Sciences, 2016;1:44-9.

Hypertrophic cardiomyopathy (HCM) is a global disease affecting people of various ethnic origins and both genders. HCM is a genetic disorder with a wide range of symptoms, including the catastrophic presentation of sudden cardiac death. Proper diagnosis and treatment of this disorder can relieve symptoms and prolong life. Non-invasive imaging is essential in diagnosing HCM. We present a review to deliberate the potential use of cardiac magnetic resonance (CMR) imaging in HCM assessment and also identify the risk factors entailed with risk stratification of HCM based on Magnetic Resonance Imaging (MRI).
Kimura Disease: A Rare Cause of Head and Neck Tumour in Children- A Case Report

Kreah MH, Misni MN, Mumin NA

Curr Med Imaging, 2021 Oct 29.
PMID: 34719375 DOI: 10.2174/1573405617666211029163214

BACKGROUND: Kimura disease is a rare inflammatory condition classically manifested as painless subcutaneous nodules in the head and neck region and associated with regional cervical lymphadenopathy and salivary gland involvement.
OBJECTIVE: The purpose of this report is to illustrate the diagnostic difficulty due to its rarity and non-specific clinical presentation.
CASE PRESENTATION: We present a case of Kimura disease with bilateral eyelid swelling, parotid involvement, and cervical lymphadenopathy in a young boy. Computed Tomography (CT) showed ill-defined enhancing masses in both upper eyelids with lacrimal gland infiltration, multiple nodular lesions in both parotid glands, and bilateral enlargement of cervical nodes. After several multidisciplinary discussions and trials of medications, Kimura's disease was finally confirmed by histology examination.
CONCLUSION: In conclusion, a rare disease such as Kimura must be considered earlier if the patient is not responding to the treatment.
Fulltext A rare case of Tuberculous Prostatitis

Nurul Yaqeen Esa, Mohammad Hanafiah, Marymol Koshy, Hilmi Abdullah, Ahmad Izuanuddin Ismail, Mohamed Fauzi Abdul Rani

Journal of Clinical and Health Sciences, 2016;1:33-36.

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.
Fulltext Proton magnetic resonance spectroscopy (1h-mrs) in studies of glaucoma: a scoping review

Liyana,Musa,, Sabrilhakim,Sidek,, Firdaus,Yusof @ Alias,, Azlan,Azha,Musa,, Mohammad,Hanafiah,, Mazuin,Mohd,Razall,

Science Letters, 2021;15(2):136-145.
MyJurnal

ABSTRACT
Glaucoma is a disease that is chronic in nature and indistinctive at an early stage, leading to late
detection. It has become a major public health problem and a leading cause of irreversible
blindness worldwide. The proton magnetic resonance spectroscopy (1H-MRS), of late, has been
utilised to evaluate metabolites concentration in the brain, especially for detecting
neurodegenerative disease. Considering that glaucoma is a neurodegenerative disease, studies on
the concentration of metabolites using 1H-MRS in glaucoma patients could be investigated. This
scoping review aims to examine the extent, range, and nature of studies on the 1H-MRS technique
in glaucoma disease. The literature search was conducted using MEDLINE, CINAHL and
SCOPUS, dated from 2000 until 2019. Studies on glaucoma using 1H-MRS were considered. Any
processing method used to characterise the metabolite concentration generated by the 1H-MRS
protocol has also been considered. Nine full-text studies were yielded after hundreds of literature
identification, screening, and eligibility assessment. The included studies sought to determine the
feasibility, change, and comparability of metabolite concentrations in glaucoma patients using 1HMRS with more studies utilising single-voxel spectroscopy (SVS) technique. The chosen anatomy
of interest could have been influenced by several criteria, including the association between
anatomy and the research query and the volume-sizing capabilities of the 1H-MRS technique. Six
(6) metabolites were significantly identified, and quantified, including N-acetyl aspartate,
Creatine, Choline, Myo-Inositol, Lactate and Glutamate-Glutamine. This scoping review points
out the 1H-MRS application in different types and severity of glaucoma, highlighting the
information on the type of patients, the detected metabolites in the anatomy involved, the 1H-MRS
technique used and the raw data decipherment processing software. Future studies are needed to
validate existing glaucoma studies and to explore the potential of detecting incipient glaucoma.
Fulltext Acanthamoeba encephalitis in an immunocompetent child and review of the imaging features of intracranial acanthamoebic infections in immunocompetent patients

Mohammad Hanafiah, Mohd Farhan Hamdan, Azura Mohamed Mukhari Shahizon, Wong, Sau Wei, Yoganathan Kanaheswari

Neurology Asia, 2018;23(2):179-184.
MyJurnal

Granulomatous amoebic encephalitis caused by Acanthamoeba is a rare entity mainly affecting
immunocompromised patients. We reported a case of Acanthamoeba encephalitis of a 1-year-old
immunocompetent child and described the CT and MRI findings of the brain, while reviewing the
relevant literatures. The imaging findings of Acanthamoeba meningoencepalitis in immunocompetent
patients are non-specific and pose a diagnostic challenge.
Fulltext A rare case of Tuberculous Prostatitis

Nurul Yaqeen Esa, Mohammad Hanafiah, Marymol Koshy, Hilmi Abdullah, Ahmad Izuanuddin Ismail, Mohamed Fauzi Abdul Rani

Journal of Clinical and Health Sciences, 2016;1(2):33-36.
MyJurnal

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.