The preliminary discussion of this short essay focuses on some of Islām’s intellectual and civilisational contributions in a historical region of Central Asia called Khurāsān. As a starting point, it mentions a number of hadīths (sayings from the Prophet Muḥammad) and athār (sayings of the Holy Prophet’s Companions and their followers) that impute to this region some eschatological importance as well as matters pertaining to the legal aspect of the religion, especially from Muslim Sunnī perspective. As a preliminary discussion and in a non-exhaustive manner, the writing highlights and evaluates a number of important Muslim figures that have emerged from that region along with their respective intellectual and cultural contributions to human civilisation as materialisation of the religion’s aspirations arising from collective understanding of its worldview.